Detailed information for compound 778276

Basic information

Technical information
  • TDR Targets ID: 778276
  • Name: N-(4-chlorophenyl)-1-oxoisochroman-3-carboxam ide
  • MW: 301.724 | Formula: C16H12ClNO3
  • H donors: 1 H acceptors: 2 LogP: 3.37 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C1OC(=O)c2c(C1)cccc2)Nc1ccc(cc1)Cl
  • InChi: 1S/C16H12ClNO3/c17-11-5-7-12(8-6-11)18-15(19)14-9-10-3-1-2-4-13(10)16(20)21-14/h1-8,14H,9H2,(H,18,19)
  • InChiKey: RPFDBBIEIYYIBH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(4-chlorophenyl)-1-oxo-isochroman-3-carboxamide
  • N-(4-chlorophenyl)-1-oxo-3-isochromancarboxamide
  • N-(4-chlorophenyl)-1-keto-isochroman-3-carboxamide
  • A3199/0135604
  • EU-0048830

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Giardia lamblia Cathepsin L precursor 0.0163 0.0681 0.2259
Plasmodium vivax serine-repeat antigen (SERA) 0.0163 0.0681 0.2912
Loa Loa (eye worm) hypothetical protein 0.0163 0.0681 0.0681
Brugia malayi Papain family cysteine protease containing protein 0.0515 0.2275 0.2271
Giardia lamblia Cathepsin L-like protease 0.0163 0.0681 0.2259
Plasmodium vivax serine-repeat antigen (SERA) 0.0163 0.0681 0.2912
Brugia malayi Papain family cysteine protease containing protein 0.0163 0.0681 0.0675
Onchocerca volvulus 0.0163 0.0681 0.2974
Brugia malayi Cathepsin L-like precursor 0.0515 0.2275 0.2271
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0681 0.087
Echinococcus multilocularis cathepsin L 0.0163 0.0681 0.0877
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0145 0.012
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0163 0.0681 0.2259
Brugia malayi RNA binding protein 0.0065 0.0236 0.023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0041 0.0041
Echinococcus granulosus geminin 0.0677 0.3009 0.3876
Loa Loa (eye worm) hypothetical protein 0.0163 0.0681 0.0681
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0515 0.2275 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0051 0.0026
Loa Loa (eye worm) hypothetical protein 0.1728 0.7762 0.7762
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0681 0.087
Giardia lamblia Cathepsin B precursor 0.0647 0.2871 1
Echinococcus granulosus caspase 2 0.0126 0.0513 0.0661
Echinococcus granulosus tissue type plasminogen activator 0.0018 0.0026 0.0033
Brugia malayi fibroinase precursor 0.0163 0.0681 0.0675
Schistosoma mansoni hypothetical protein 0.0396 0.1737 0.2232
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Loa Loa (eye worm) ctsf protein 0.0515 0.2275 0.2275
Giardia lamblia Cathepsin L-like protease 0.0163 0.0681 0.2259
Echinococcus granulosus smad 0.0016 0.0015 0.002
Trypanosoma cruzi cysteine peptidase, putative 0.0702 0.3119 0.3102
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0163 0.0681 0.2259
Echinococcus granulosus intermediate filament protein 0.0026 0.0061 0.0079
Onchocerca volvulus Cathepsin L homolog 0.0163 0.0681 0.2974
Entamoeba histolytica cysteine protease, putative 0.0163 0.0681 0.2862
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0163 0.0681 0.2912
Brugia malayi MH2 domain containing protein 0.0016 0.0015 0.001
Giardia lamblia Cysteine protease 0.0163 0.0681 0.2259
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Plasmodium falciparum serine repeat antigen 3 0.0163 0.0681 0.2912
Schistosoma mansoni histone deacetylase hda2 0.0045 0.0145 0.018
Echinococcus multilocularis cathepsin b 0.1728 0.7762 1
Echinococcus granulosus cathepsin L 0.0163 0.0681 0.0877
Echinococcus multilocularis snurportin 1 0.0316 0.1371 0.1766
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0354 0.0354
Leishmania major cathepsin L-like protease 0.0515 0.2275 0.2255
Leishmania major cysteine peptidase A (CPA) 0.0515 0.2275 0.2255
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0163 0.0681 0.2259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Entamoeba histolytica cysteine proteinase, putative 0.0214 0.0912 0.3899
Giardia lamblia Cathepsin B precursor 0.0163 0.0681 0.2259
Brugia malayi Histone deacetylase family protein 0.0045 0.0145 0.014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0354 0.0449
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Giardia lamblia Cathepsin L precursor 0.0163 0.0681 0.2259
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0236 0.023
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0077 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0214 0.0912 0.0875
Echinococcus multilocularis histone deacetylase 6 0.0045 0.0145 0.0187
Brugia malayi MH1 domain containing protein 0.0016 0.0015 0.001
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0061 0.0061
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0354 0.0456
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0236 0.0297
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0163 0.0681 0.2259
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0647 0.2871 1
Echinococcus granulosus gamma secretase subunit aph 1 0.0255 0.1095 0.1411
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0163 0.0681 0.2259
Brugia malayi cathepsin F-like cysteine proteinase 0.0163 0.0681 0.0675
Brugia malayi hypothetical protein 0.0126 0.0513 0.0508
Echinococcus granulosus p2X purinoceptor 4 0.0067 0.0246 0.0317
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0155 0.015
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0515 0.2275 0.7894
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0163 0.0681 0.0681
Echinococcus multilocularis lamin dm0 0.0026 0.0061 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0163 0.0681 0.2259
Echinococcus granulosus histone deacetylase 6 0.0045 0.0145 0.0187
Echinococcus granulosus histone deacetylase 6 0.0045 0.0145 0.0187
Echinococcus granulosus laminin 0.0014 0.0006 0.0007
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0041 0.0016
Loa Loa (eye worm) hypothetical protein 0.0163 0.0681 0.0681
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0175 0.0149
Schistosoma mansoni gamma-secretase subunit aph-1 0.0255 0.1095 0.1404
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0163 0.0681 0.087
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0014 0.0006 0.0006
Trypanosoma brucei histone deacetylase 3 0.0045 0.0145 0.0104
Trypanosoma brucei histone deacetylase, putative 0.0045 0.0145 0.0104
Leishmania major GTP-binding protein, putative 0.0022 0.0041 0.0016
Onchocerca volvulus 0.0047 0.0155 0.0658
Echinococcus multilocularis cathepsin L cysteine protease 0.0515 0.2275 0.2931
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0681 0.2259
Schistosoma mansoni lamin 0.0026 0.0061 0.0072
Giardia lamblia Cathepsin L precursor 0.0163 0.0681 0.2259
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0015 0.002
Brugia malayi Cathepsin L-like precursor 0.0464 0.2043 0.2039
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0014 0.0006 0.0006
Onchocerca volvulus Deterin homolog 0.0219 0.0932 0.4083
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0163 0.0681 0.087
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0182 0.0614
Leishmania major cathepsin L-like protease 0.0515 0.2275 0.2255
Brugia malayi Cathepsin L-like precursor 0.0515 0.2275 0.2271
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0214 0.0912 0.1169
Entamoeba histolytica cysteine protease, putative 0.0163 0.0681 0.2862
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0041 0.0053
Echinococcus granulosus Tolloid protein 1 0.0014 0.0006 0.0007
Giardia lamblia Cathepsin B precursor 0.0163 0.0681 0.2259
Echinococcus granulosus lamin 0.0026 0.0061 0.0079
Toxoplasma gondii cathepsin B 0.0647 0.2871 1
Echinococcus multilocularis smad 0.0016 0.0015 0.002
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0006 0.0006
Onchocerca volvulus 0.0515 0.2275 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0681 0.2259
Brugia malayi Papain family cysteine protease containing protein 0.0163 0.0681 0.0675
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0163 0.0681 0.087
Trypanosoma brucei C-8 sterol isomerase, putative 0.2222 1 1
Schistosoma mansoni importin beta-1 0.003 0.0077 0.0092
Plasmodium vivax histone deacetylase 2, putative 0.0045 0.0145 0.0532
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0163 0.0681 0.2912
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0647 0.2871 0.2852
Schistosoma mansoni cpg binding protein 0.0028 0.0069 0.0082
Schistosoma mansoni cathepsin S (C01 family) 0.0163 0.0681 0.087
Schistosoma mansoni ran 0.0022 0.0041 0.0046
Schistosoma mansoni intermediate filament proteins 0.0026 0.0061 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus granulosus survival motor neuron protein 1 0.023 0.0983 0.1266
Onchocerca volvulus Cathepsin L homolog 0.0515 0.2275 1
Toxoplasma gondii preprocathepsin c precursor, putative 0.0163 0.0681 0.2356
Onchocerca volvulus Cathepsin L homolog 0.0515 0.2275 1
Echinococcus multilocularis p2X purinoceptor 4 0.0067 0.0246 0.0317
Echinococcus multilocularis p2X purinoceptor 4 0.0067 0.0246 0.0317
Schistosoma mansoni smad1 5 8 and 0.0016 0.0015 0.0013
Echinococcus granulosus cathepsin b 0.1728 0.7762 1
Trypanosoma cruzi cysteine proteinase, putative 0.0214 0.0912 0.0889
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0214 0.0912 0.1169
Toxoplasma gondii cathepsin CPL 0.0515 0.2275 0.7921
Loa Loa (eye worm) TK/ROR protein kinase 0.0018 0.0026 0.0026
Brugia malayi gamma-secretase subunit aph-1 0.0255 0.1095 0.109
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0316 0.1371 0.1371
Plasmodium vivax unspecified product 0.0163 0.0681 0.2912
Schistosoma mansoni lamin 0.0026 0.0061 0.0072
Schistosoma mansoni cathepsin B (C01 family) 0.0163 0.0681 0.087
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.0983 0.1266
Plasmodium falciparum serine repeat antigen 1 0.0163 0.0681 0.2912
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0041 0.0036
Onchocerca volvulus 0.0028 0.0069 0.0279
Trypanosoma cruzi cysteine peptidase, putative 0.0214 0.0912 0.0889
Leishmania major cathepsin L-like protease 0.0515 0.2275 0.2255
Schistosoma mansoni cathepsin F (C01 family) 0.0515 0.2275 0.2926
Brugia malayi Cathepsin L-like precursor 0.0464 0.2043 0.2039
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0051 0.0035
Loa Loa (eye worm) hypothetical protein 0.0464 0.2043 0.2043
Loa Loa (eye worm) histone deacetylase 0.0045 0.0145 0.0145
Echinococcus granulosus histone deacetylase 6 0.0045 0.0145 0.0187
Loa Loa (eye worm) hypothetical protein 0.023 0.0983 0.0983
Echinococcus multilocularis caspase 2 0.0126 0.0513 0.0661
Loa Loa (eye worm) transcription factor SMAD2 0.0235 0.1005 0.1005
Entamoeba histolytica cysteine proteinase 1, putative 0.0214 0.0912 0.3899
Schistosoma mansoni cathepsin s 0.0051 0.0175 0.0218
Schistosoma mansoni hypothetical protein 0.0677 0.3009 0.3872
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.1737 0.2237
Loa Loa (eye worm) hypothetical protein 0.003 0.0077 0.0077
Schistosoma mansoni hypothetical protein 0.0677 0.3009 0.3872
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0163 0.0681 0.2862
Schistosoma mansoni cathepsin C 0.0163 0.0681 0.087
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.021 0.0264
Echinococcus granulosus histone deacetylase 0.0045 0.0145 0.0187
Brugia malayi Cathepsin L-like precursor 0.0051 0.0175 0.0169
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0214 0.0912 0.0875
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0214 0.0912 0.3078
Loa Loa (eye worm) hypothetical protein 0.1136 0.5083 0.5083
Brugia malayi cathepsin L-like precursor 0.0464 0.2043 0.2039
Echinococcus granulosus Smad4 0.0016 0.0015 0.002
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0681 0.087
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Echinococcus granulosus apoptotic protease activating factor 1 0.0126 0.0513 0.0661
Plasmodium vivax vivapain-2 0.0515 0.2275 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0163 0.0681 0.2912
Trypanosoma cruzi cysteine peptidase, putative 0.0702 0.3119 0.3102
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0214 0.0912 0.0889
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0175 0.0175
Schistosoma mansoni hypothetical protein 0.0126 0.0513 0.0655
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0219 0.0932 0.1201
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1728 0.7762 1
Echinococcus granulosus p2X purinoceptor 4 0.0067 0.0246 0.0317
Brugia malayi CXXC zinc finger family protein 0.0028 0.0069 0.0063
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0015 0.002
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0515 0.2275 0.2275
Echinococcus multilocularis histone deacetylase 7 0.0045 0.0145 0.0187
Brugia malayi Cell death protein 3 precursor 0.0126 0.0513 0.0508
Toxoplasma gondii histone deacetylase HDAC1 0.0045 0.0145 0.0488
Entamoeba histolytica cysteine protease, putative 0.0163 0.0681 0.2862
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0015 0.0013
Brugia malayi Cathepsin L-like precursor 0.0515 0.2275 0.2271
Plasmodium falciparum serine repeat antigen 2 0.0163 0.0681 0.2912
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0236 0.0304
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0163 0.0681 0.2912
Loa Loa (eye worm) histone deacetylase 7A 0.0045 0.0145 0.0145
Loa Loa (eye worm) fibroinase 0.0515 0.2275 0.2275
Echinococcus granulosus microtubule associated protein 2 0.0699 0.3108 0.4004
Toxoplasma gondii kringle domain-containing protein 0.0018 0.0026 0.007
Onchocerca volvulus 0.0219 0.0932 0.4083
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0051 0.0175 0.0169
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Onchocerca volvulus 0.0515 0.2275 1
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0163 0.0681 0.2259
Echinococcus granulosus snurportin 1 0.0316 0.1371 0.1766
Schistosoma mansoni cathepsin F (C01 family) 0.0515 0.2275 0.2926
Schistosoma mansoni cpg binding protein 0.0029 0.0076 0.0091
Entamoeba histolytica cysteine protease, putative 0.0515 0.2275 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.0061
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0219 0.0932 0.1201
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Giardia lamblia Encystation-specific protease 0.0163 0.0681 0.2259
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0163 0.0681 0.0681
Schistosoma mansoni cathepsin F (C01 family) 0.0464 0.2043 0.2627
Onchocerca volvulus 0.0018 0.0026 0.0088
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Echinococcus multilocularis laminin 0.0014 0.0006 0.0007
Giardia lamblia Cathepsin B precursor 0.0647 0.2871 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0163 0.0681 0.2912
Brugia malayi cathepsin L precursor 0.0163 0.0681 0.0675
Giardia lamblia Cathepsin B precursor 0.0647 0.2871 1
Plasmodium falciparum serine repeat antigen 9 0.0163 0.0681 0.2912
Entamoeba histolytica hypothetical protein 0.0163 0.0681 0.2862
Echinococcus multilocularis cysteine protease 0.0515 0.2275 0.2931
Leishmania major C-8 sterol isomerase-like protein 0.2222 1 1
Schistosoma mansoni histone deacetylase 4 5 0.0045 0.0145 0.018
Giardia lamblia Cathepsin B precursor 0.0163 0.0681 0.2259
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0163 0.0681 0.087
Trypanosoma cruzi cruzipain precursor, putative 0.0702 0.3119 0.3102
Plasmodium vivax vivapain-1 0.0214 0.0912 0.3942
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0077 0.0248
Onchocerca volvulus 0.0126 0.0513 0.2238
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0651 0.2887 0.2869
Leishmania major cathepsin L-like protease 0.0702 0.3119 0.3102
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0015 0.002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0392 0.0367
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0354 0.0456
Echinococcus multilocularis gamma secretase subunit aph 1 0.0255 0.1095 0.1411
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0163 0.0681 0.2912
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0163 0.0681 0.2912
Plasmodium falciparum serine repeat antigen 8 0.0163 0.0681 0.2912
Trichomonas vaginalis conserved hypothetical protein 0.0163 0.0681 0.2259
Brugia malayi cathepsin Z-like cysteine proteinase 0.0163 0.0681 0.0675
Giardia lamblia Cysteine protease 0.0163 0.0681 0.2259
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0681 0.087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Leishmania major histone deacetylase, putative 0.0045 0.0145 0.012
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0041 0.007
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0163 0.0681 0.0681
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0236 0.0297
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0163 0.0681 0.2912
Echinococcus granulosus cathepsin L cysteine protease 0.0214 0.0912 0.1175
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1728 0.7762 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0061 0.0061
Echinococcus multilocularis histone deacetylase 6 0.0045 0.0145 0.0187
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Schistosoma mansoni caspase-7 (C14 family) 0.0126 0.0513 0.0655
Giardia lamblia Cathepsin B precursor 0.0163 0.0681 0.2259
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0354 0.0449
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0163 0.0681 0.2259
Brugia malayi MH1 domain containing protein 0.0016 0.0015 0.001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0354 0.0449
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Echinococcus multilocularis Smad4 0.0016 0.0015 0.002
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1728 0.7762 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0354 0.0456
Schistosoma mansoni smad1 5 8 and 0.0016 0.0015 0.0013
Brugia malayi cathepsin B-like cysteine proteinase 0.1728 0.7762 0.7761
Loa Loa (eye worm) hypothetical protein 0.0126 0.0513 0.0513
Echinococcus multilocularis microtubule associated protein 2 0.0699 0.3108 0.4004
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0647 0.2871 0.3694
Echinococcus multilocularis histone deacetylase 0.0045 0.0145 0.0187
Loa Loa (eye worm) hypothetical protein 0.0045 0.0145 0.0145
Brugia malayi hypothetical protein 0.023 0.0983 0.0978
Brugia malayi MH2 domain containing protein 0.0016 0.0015 0.001
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0163 0.0681 0.2912
Echinococcus multilocularis importin subunit beta 1 0.003 0.0077 0.0099
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0163 0.0681 0.0675
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Brugia malayi TAR-binding protein 0.0065 0.0236 0.023
Echinococcus multilocularis tissue type plasminogen activator 0.0018 0.0026 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Brugia malayi intermediate filament protein 0.0026 0.0061 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0214 0.0912 0.3078
Plasmodium vivax importin-beta 2, putative 0.003 0.0077 0.0227
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0163 0.0681 0.2259
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0354 0.0349
Echinococcus multilocularis p2X purinoceptor 4 0.0067 0.0246 0.0317
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0236 0.0297
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus granulosus cathepsin L 0.0214 0.0912 0.1175
Trypanosoma cruzi cysteine proteinase, putative 0.0214 0.0912 0.0889
Giardia lamblia Cathepsin L precursor 0.0163 0.0681 0.2259
Plasmodium vivax unspecified product 0.0214 0.0912 0.3942
Entamoeba histolytica cysteine proteinase, putative 0.0214 0.0912 0.3899
Onchocerca volvulus 0.0464 0.2043 0.8979
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0163 0.0681 0.2912
Trypanosoma cruzi C-8 sterol isomerase, putative 0.2222 1 1
Echinococcus multilocularis Tolloid protein 1 0.0014 0.0006 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0077 0.0035
Giardia lamblia Cysteine protease 0.0163 0.0681 0.2259
Giardia lamblia Cathepsin L precursor 0.0163 0.0681 0.2259
Echinococcus multilocularis lamin 0.0026 0.0061 0.0079
Onchocerca volvulus Cell death protein 3 homolog 0.0126 0.0513 0.2238
Toxoplasma gondii cathepsin CPC1 0.0163 0.0681 0.2356
Loa Loa (eye worm) hypothetical protein 0.0045 0.0145 0.0145
Entamoeba histolytica cysteine protease, putative 0.0163 0.0681 0.2862
Loa Loa (eye worm) hypothetical protein 0.0464 0.2043 0.2043
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0219 0.0932 0.0927
Plasmodium vivax vivapain-3 0.0214 0.0912 0.3942
Echinococcus granulosus tar DNA binding protein 0.0065 0.0236 0.0304
Giardia lamblia Cathepsin L precursor 0.0163 0.0681 0.2259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0681 0.2259
Leishmania major cathepsin L-like protease 0.0515 0.2275 0.2255
Schistosoma mansoni Smad4 0.0016 0.0015 0.0013
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0041 0.0016
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Brugia malayi MH2 domain containing protein 0.0235 0.1005 0.1
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0236 0.0236
Echinococcus multilocularis cathepsin b 0.1728 0.7762 1
Echinococcus granulosus importin subunit beta 1 0.003 0.0077 0.0099
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0214 0.0912 0.1169
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Brugia malayi Cathepsin L-like precursor 0.0515 0.2275 0.2271
Schistosoma mansoni smad 0.0016 0.0015 0.0013
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0051 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus granulosus histone deacetylase 7 0.0045 0.0145 0.0187
Loa Loa (eye worm) hypothetical protein 0.0026 0.0059 0.0059
Schistosoma mansoni hypothetical protein 0.0018 0.0026 0.0026
Trypanosoma brucei Aph-1 protein, putative 0.0099 0.0392 0.0352
Schistosoma mansoni microtubule-associated protein tau 0.0699 0.3108 0.3999
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0163 0.0681 0.2912
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0145 0.012
Brugia malayi Cathepsin L-like precursor 0.0515 0.2275 0.2271
Echinococcus granulosus cathepsin l cysteine peptidase 0.0515 0.2275 0.2931
Brugia malayi Cytochrome P450 family protein 0.0022 0.0042 0.0037
Brugia malayi cathepsin F-like cysteine proteinase 0.0051 0.0175 0.0169
Brugia malayi cathepsin Z-like cysteine proteinase 0.0163 0.0681 0.0675
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0681 0.2259
Plasmodium falciparum serine repeat antigen 7 0.0163 0.0681 0.2912
Onchocerca volvulus 0.0515 0.2275 1
Brugia malayi Importin beta-1 subunit 0.003 0.0077 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0236 0.0297
Plasmodium vivax histone deacetylase, putative 0.0045 0.0145 0.0532
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Echinococcus granulosus dnaJ subfamily B 0.0396 0.1737 0.2237
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1728 0.7762 1
Entamoeba histolytica cysteine proteinase 2 0.0214 0.0912 0.3899
Onchocerca volvulus 0.0515 0.2275 1
Brugia malayi Protein kinase domain containing protein 0.0018 0.0026 0.002
Echinococcus multilocularis fibrillin 1 0.0014 0.0006 0.0007
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0061 0.0056
Plasmodium falciparum importin beta, putative 0.003 0.0077 0.0227
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0515 0.2275 0.2931
Leishmania major histone deacetylase, putative 0.0045 0.0145 0.012
Loa Loa (eye worm) hypothetical protein 0.0219 0.0932 0.0932
Echinococcus granulosus cathepsin l1 0.0464 0.2043 0.2632
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0515 0.2275 0.2931
Schistosoma mansoni hypothetical protein 0.0219 0.0932 0.1195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Trypanosoma cruzi cruzipain precursor, putative 0.0051 0.0175 0.0149
Loa Loa (eye worm) Smad1 0.0016 0.0015 0.0015
Trypanosoma cruzi major cysteine proteinase, putative 0.0349 0.1525 0.1503
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Entamoeba histolytica cysteine protease, putative 0.0163 0.0681 0.2862
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0681 0.2259
Giardia lamblia Hypothetical protein 0.0163 0.0681 0.2259
Trypanosoma brucei histone deacetylase 4 0.0045 0.0145 0.0104
Entamoeba histolytica cysteine proteinase, putative 0.0464 0.2043 0.8962
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1728 0.7762 0.7756
Trypanosoma cruzi cysteine protease, putative 0.0214 0.0912 0.0889
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0163 0.0681 0.2862
Entamoeba histolytica cysteine protease, putative 0.0163 0.0681 0.2862
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0163 0.0681 0.2259
Loa Loa (eye worm) hypothetical protein 0.0051 0.0175 0.0175
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0163 0.0681 0.2259
Plasmodium falciparum serine repeat antigen 4 0.0163 0.0681 0.2912
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0163 0.0681 0.2912
Giardia lamblia Cathepsin B precursor 0.0163 0.0681 0.2259
Loa Loa (eye worm) cathepsin B 0.0647 0.2871 0.2871
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0051 0.0035
Echinococcus multilocularis cpg binding protein 0.0029 0.0076 0.0098
Brugia malayi Cathepsin L-like precursor 0.0515 0.2275 0.2271
Brugia malayi Papain family cysteine protease containing protein 0.0214 0.0912 0.0907
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0219 0.0932 0.1195
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0163 0.0681 0.0681
Echinococcus multilocularis cysteine protease 0.0515 0.2275 0.2931
Schistosoma mansoni smad1 5 8 and 0.0016 0.0015 0.0013
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0354 0.0456
Schistosoma mansoni hypothetical protein 0.0316 0.1371 0.176
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0041 0.0125
Brugia malayi RNA, U transporter 1 0.0084 0.0323 0.0318
Giardia lamblia Hypothetical protein 0.0163 0.0681 0.2259
Brugia malayi Papain family cysteine protease containing protein 0.0214 0.0912 0.0907
Echinococcus granulosus cathepsin L cysteine proteinase 0.0515 0.2275 0.2931
Entamoeba histolytica cysteine protease, putative 0.0214 0.0912 0.3899
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Leishmania major cathepsin L-like protease 0.0702 0.3119 0.3102
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0042 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0464 0.2043 0.7075
Schistosoma mansoni P2X receptor subunit 0.0067 0.0246 0.031
Schistosoma mansoni P2X receptor subunit 0.0067 0.0246 0.031
Echinococcus multilocularis musashi 0.0026 0.0061 0.0079
Echinococcus multilocularis cathepsin L 0.0214 0.0912 0.1175
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0236 0.0297
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0041 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0219 0.0932 0.0927
Loa Loa (eye worm) hypothetical protein 0.0051 0.0175 0.0175
Entamoeba histolytica cysteine proteinase, putative 0.0214 0.0912 0.3899
Loa Loa (eye worm) hypothetical protein 0.0515 0.2275 0.2275
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.0026
Leishmania major importin beta-1 subunit, putative 0.0024 0.0051 0.0026
Echinococcus granulosus inhibitor of apoptosis protein 0.0219 0.0932 0.1201
Brugia malayi Kringle domain containing protein 0.0018 0.0026 0.002
Echinococcus multilocularis geminin 0.0677 0.3009 0.3876
Echinococcus granulosus cathepsin b 0.1728 0.7762 1
Schistosoma mansoni hypothetical protein 0.0047 0.0155 0.0193
Leishmania major cathepsin L-like protease 0.0515 0.2275 0.2255
Trypanosoma cruzi major cysteine proteinase, putative 0.0163 0.0681 0.0657
Trypanosoma cruzi cysteine peptidase, putative 0.0702 0.3119 0.3102
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Onchocerca volvulus 0.0026 0.0061 0.0245
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0702 0.3119 0.3091
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0647 0.2871 0.2852
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0464 0.2043 0.7075
Plasmodium falciparum serine repeat antigen 5 0.0163 0.0681 0.2912
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0163 0.0681 0.2259
Loa Loa (eye worm) MH2 domain-containing protein 0.0235 0.1005 0.1005
Schistosoma mansoni survival motor neuron protein 0.0047 0.0155 0.0193
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0015 0.0015
Echinococcus granulosus cpg binding protein 0.0029 0.0076 0.0098
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Leishmania major cathepsin L-like protease 0.0702 0.3119 0.3102
Entamoeba histolytica cysteine proteinase, putative 0.0515 0.2275 1
Plasmodium vivax unspecified product 0.0051 0.0175 0.0663
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0255 0.1095 0.1095
Plasmodium falciparum cysteine proteinase falcipain 3 0.0515 0.2275 1
Plasmodium falciparum serine repeat antigen 6 0.0163 0.0681 0.2912
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0515 0.2275 0.7894
Echinococcus granulosus p2X purinoceptor 4 0.0067 0.0246 0.0317
Trypanosoma brucei cysteine peptidase C (CPC) 0.0647 0.2871 0.2841
Trypanosoma cruzi cysteine peptidase, putative 0.0515 0.2275 0.2255
Giardia lamblia Cysteine protease 0.0163 0.0681 0.2259
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0015 0.002
Entamoeba histolytica cysteine proteinase, putative 0.0515 0.2275 1
Loa Loa (eye worm) hypothetical protein 0.0163 0.0681 0.0681
Echinococcus multilocularis cathepsin L cysteine protease 0.0515 0.2275 0.2931
Loa Loa (eye worm) hypothetical protein 0.0219 0.0932 0.0932
Onchocerca volvulus 0.0515 0.2275 1
Loa Loa (eye worm) hypothetical protein 0.0163 0.0681 0.0681
Loa Loa (eye worm) RNA binding protein 0.0065 0.0236 0.0236
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0392 0.0367
Brugia malayi Cathepsin L-like cysteine proteinase 0.0464 0.2043 0.2039
Schistosoma mansoni histone deacetylase 4 5 0.0045 0.0145 0.018
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0014 0.0006 0.0006
Toxoplasma gondii cathepsin CPC2 0.0163 0.0681 0.2356
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0006 0.0001
Echinococcus granulosus cathepsin l1 0.0515 0.2275 0.2931
Plasmodium vivax vivapain-2 0.0515 0.2275 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0163 0.0681 0.2259
Echinococcus multilocularis apoptotic protease activating factor 1 0.0126 0.0513 0.0661
Onchocerca volvulus 0.0515 0.2275 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0163 0.0681 0.2259
Schistosoma mansoni cpg binding protein 0.0029 0.0076 0.0091
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0515 0.2275 1
Echinococcus granulosus cysteine protease 0.0214 0.0912 0.1175
Loa Loa (eye worm) cysteine protease 0.0515 0.2275 0.2275
Schistosoma mansoni inhibitor of apoptosis protein 0.0219 0.0932 0.1195
Entamoeba histolytica cysteine proteinase, putative 0.0214 0.0912 0.3899
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0163 0.0681 0.2912
Brugia malayi cathepsin L-like cysteine proteinase 0.0163 0.0681 0.0675
Plasmodium falciparum cysteine proteinase falcipain 1 0.0214 0.0912 0.3942
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0145 0.012
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0041 0.0053
Onchocerca volvulus 0.0515 0.2275 1
Plasmodium falciparum histone deacetylase, putative 0.0045 0.0145 0.0532
Brugia malayi Histone deacetylase family protein 0.0045 0.0145 0.014
Echinococcus multilocularis histone deacetylase 6 0.0045 0.0145 0.0187
Plasmodium falciparum histone deacetylase 2 0.0045 0.0145 0.0532
Brugia malayi Smad1 0.0016 0.0015 0.001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0515 0.2275 0.7894
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0015 0.0015
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0163 0.0681 0.2259
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0515 0.2275 0.2275
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0163 0.0681 0.2259
Loa Loa (eye worm) hypothetical protein 0.0464 0.2043 0.2043
Schistosoma mansoni P2X receptor subunit 0.0067 0.0246 0.031
Schistosoma mansoni ran 0.0022 0.0041 0.0046
Entamoeba histolytica hypothetical protein 0.0024 0.0051 0.0045
Onchocerca volvulus Cathepsin F homolog 0.0515 0.2275 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0513 0.0513
Brugia malayi Papain family cysteine protease containing protein 0.0163 0.0681 0.0675
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0236 0.0236
Schistosoma mansoni P2X receptor subunit 0.0067 0.0246 0.031
Loa Loa (eye worm) hypothetical protein 0.2222 1 1
Onchocerca volvulus 0.0026 0.0061 0.0245
Loa Loa (eye worm) hypothetical protein 0.0051 0.0175 0.0175
Echinococcus granulosus lamin dm0 0.0026 0.0061 0.0079
Echinococcus multilocularis inhibitor of apoptosis protein 0.0219 0.0932 0.1201
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0163 0.0681 0.087
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0163 0.0681 0.2259

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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