Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.004 | 0.0128 | 0.0101 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0368 | 0.3761 | 0.9484 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.005 | 0.0246 | 0.022 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0117 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0689 | 0.0664 |
Plasmodium falciparum | thioredoxin reductase | 0.0145 | 0.1295 | 0.3232 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0039 | 0.0117 | 0.0091 |
Leishmania major | NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe | 0.0385 | 0.3952 | 0.38 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0145 | 0.1295 | 0.1272 |
Leishmania major | trypanothione reductase | 0.0145 | 0.1295 | 0.1076 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0385 | 0.3952 | 0.3936 |
Schistosoma mansoni | serine/threonine protein kinase | 0.004 | 0.0128 | 0.0101 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0117 | 0.0117 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 0.291 | 0.291 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0042 | 0.0159 | 0.0132 |
Schistosoma mansoni | serine/threonine protein kinase | 0.004 | 0.0128 | 0.0101 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0368 | 0.3761 | 1 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0039 | 0.0117 | 0.0091 |
Trichomonas vaginalis | glutaminase, putative | 0.0559 | 0.5879 | 0.5879 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.0406 | 0.0381 |
Trichomonas vaginalis | glutathione reductase, putative | 0.005 | 0.0246 | 0.0246 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0266 | 0.024 |
Giardia lamblia | Transcriptional regulator, Sir2 family | 0.0385 | 0.3952 | 0.3936 |
Echinococcus multilocularis | NAD dependent deacetylase sirtuin 3 | 0.0931 | 1 | 1 |
Echinococcus granulosus | NAD dependent deacetylase sirtuin 7 | 0.0239 | 0.2341 | 0.2321 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.005 | 0.0246 | 0.022 |
Mycobacterium tuberculosis | Transcriptional regulatory protein | 0.0385 | 0.3952 | 1 |
Echinococcus granulosus | axis inhibition protein axin | 0.0039 | 0.0117 | 0.0091 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0128 | 0.0128 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0075 | 0.0525 | 0.0495 |
Leishmania major | sir2-family protein-like protein | 0.0239 | 0.2341 | 0.2148 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0655 | 0.6941 | 0.6864 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0368 | 0.3761 | 0.9484 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0931 | 1 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0037 | 0.0098 | 0.0071 |
Onchocerca volvulus | 0.009 | 0.0689 | 0.2296 | |
Onchocerca volvulus | 0.009 | 0.0689 | 0.2296 | |
Mycobacterium ulcerans | citrate lyase beta subunit, CitE_2 | 0.0075 | 0.0525 | 0.0495 |
Onchocerca volvulus | 0.009 | 0.0689 | 0.2296 | |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0145 | 0.1295 | 0.1076 |
Schistosoma mansoni | serine/threonine protein kinase | 0.004 | 0.0128 | 0.0101 |
Brugia malayi | glutathione reductase | 0.0145 | 0.1295 | 0.1272 |
Mycobacterium ulcerans | hypothetical protein | 0.0075 | 0.0525 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.0341 | 0.3466 | 0.3448 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0117 | 0.0117 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0039 | 0.0117 | 0.0091 |
Onchocerca volvulus | 0.0031 | 0.0033 | 0.0023 | |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.009 | 0.0689 | 0.0664 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.005 | 0.0246 | 0.022 |
Trypanosoma cruzi | Silent information regulator 2 related protein 1 | 0.0931 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0117 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0117 | 0.0091 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.0406 | 0.0381 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.0471 | 0.0446 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0033 | 0.0007 |
Loa Loa (eye worm) | RGS-3 protein | 0.0039 | 0.0117 | 0.0091 |
Schistosoma mansoni | regulator of G protein signaling | 0.0039 | 0.0117 | 0.0091 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0039 | 0.0117 | 0.0091 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0406 | 0.0381 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.0471 | 0.0446 |
Loa Loa (eye worm) | sirtuin 4 | 0.0239 | 0.2341 | 0.2321 |
Echinococcus multilocularis | NAD dependent deacetylase sirtuin 6 | 0.0239 | 0.2341 | 0.2321 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0039 | 0.0117 | 0.0091 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.01 | 0.0793 | 0.0769 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0406 | 0.0381 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.0406 | 0.0381 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.005 | 0.0246 | 0.0559 |
Mycobacterium ulcerans | NAD-dependent deacetylase | 0.0385 | 0.3952 | 0.6579 |
Mycobacterium ulcerans | hypothetical protein | 0.0075 | 0.0525 | 0.0495 |
Echinococcus multilocularis | chromatin regulatory protein sir2 | 0.0931 | 1 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.005 | 0.0246 | 0.0559 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0117 | 0.0117 |
Schistosoma mansoni | glutaminase | 0.0559 | 0.5879 | 0.5868 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0267 | 0.0241 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0037 | 0.0099 | 0.0072 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0039 | 0.0117 | 0.0117 |
Leishmania major | hypothetical protein, conserved | 0.0655 | 0.6941 | 0.6864 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0239 | 0.2341 | 0.2321 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0039 | 0.0117 | 0.0091 |
Loa Loa (eye worm) | glutaminase 2 | 0.0559 | 0.5879 | 0.5868 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0581 | 0.6117 | 0.6117 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0291 | 0.291 | 0.2825 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0117 | 0.0117 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0239 | 0.2341 | 0.2341 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0117 | 0.0117 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.004 | 0.0128 | 0.0101 |
Brugia malayi | PXA domain containing protein | 0.0039 | 0.0117 | 0.0091 |
Echinococcus granulosus | axis inhibition protein axin | 0.0039 | 0.0117 | 0.0091 |
Echinococcus granulosus | NAD dependent deacetylase sirtuin 6 | 0.0239 | 0.2341 | 0.2321 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0291 | 0.291 | 0.2731 |
Brugia malayi | PXA domain containing protein | 0.0039 | 0.0117 | 0.0091 |
Trypanosoma cruzi | Silent information regulator 2 related protein 1 | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0063 | 0.0386 | 0.036 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0291 | 0.291 | 0.2731 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0331 | 0.3352 | 0.8381 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0039 | 0.0117 | 0.0091 |
Echinococcus granulosus | jumonji domain containing protein | 0.0042 | 0.0159 | 0.0132 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0291 | 0.291 | 0.2891 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0931 | 1 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0291 | 0.291 | 0.2891 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.009 | 0.0689 | 0.0664 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0039 | 0.0117 | 0.0091 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.004 | 0.0128 | 0.0351 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0098 | 0.0071 |
Brugia malayi | Hypothetical tyrosinase-like protein F21C3.2 in chromosome I | 0.009 | 0.0689 | 0.0664 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.0406 | 0.0381 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0098 | 0.0071 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0385 | 0.3952 | 0.3952 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0266 | 0.024 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.005 | 0.0246 | 0.0559 |
Echinococcus multilocularis | citrate lyase subunit beta protein | 0.0075 | 0.0525 | 0.0499 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.0471 | 0.0471 |
Giardia lamblia | Kinase, PLK | 0.0291 | 0.291 | 0.2891 |
Echinococcus granulosus | citrate lyase subunit beta protein | 0.0075 | 0.0525 | 0.0499 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0117 | 0.0091 |
Plasmodium vivax | hypothetical protein, conserved | 0.0239 | 0.2341 | 0.5896 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.0471 | 0.0471 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0039 | 0.0117 | 0.0091 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.0471 | 0.0446 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0291 | 0.291 | 0.2891 |
Plasmodium vivax | glutathione reductase, putative | 0.0145 | 0.1295 | 0.3232 |
Brugia malayi | RNA binding protein | 0.0065 | 0.0406 | 0.0381 |
Trypanosoma cruzi | Silent information regulator 2 related protein 3 | 0.0385 | 0.3952 | 0.38 |
Echinococcus granulosus | NAD dependent deacetylase sirtuin 1 | 0.0581 | 0.6117 | 0.6106 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.0471 | 0.0446 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.004 | 0.0128 | 0.0101 |
Toxoplasma gondii | thioredoxin reductase | 0.0145 | 0.1295 | 0.3232 |
Brugia malayi | ShTK domain containing protein | 0.009 | 0.0689 | 0.0664 |
Toxoplasma gondii | histone deacetylase SIR2 | 0.0385 | 0.3952 | 1 |
Schistosoma mansoni | tyrosinase precursor | 0.009 | 0.0689 | 0.0664 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0931 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.005 | 0.0246 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0128 | 0.0101 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0039 | 0.0117 | 0.0091 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0039 | 0.0117 | 0.0091 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0291 | 0.291 | 0.2891 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0039 | 0.0117 | 0.0091 |
Schistosoma mansoni | regulator of G protein signaling | 0.0039 | 0.0117 | 0.0091 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0161 | 0.0161 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0581 | 0.6117 | 0.6117 |
Leishmania major | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0075 | 0.0525 | 0.0286 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.005 | 0.0246 | 0.022 |
Brugia malayi | jmjC domain containing protein | 0.01 | 0.0793 | 0.0769 |
Brugia malayi | transcriptional regulator, Sir2 family protein | 0.0239 | 0.2341 | 0.2321 |
Mycobacterium tuberculosis | Conserved protein | 0.0075 | 0.0525 | 0.0752 |
Plasmodium falciparum | thioredoxin reductase | 0.005 | 0.0246 | 0.0559 |
Brugia malayi | NAD-dependent deacetylase SIRT1 | 0.0581 | 0.6117 | 0.6106 |
Echinococcus multilocularis | expressed protein | 0.0752 | 0.8014 | 0.8009 |
Mycobacterium tuberculosis | Probable reductase | 0.0331 | 0.3352 | 0.8381 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 0.291 | 0.291 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0331 | 0.3352 | 0.8339 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 0.291 | 0.291 |
Loa Loa (eye worm) | transcriptional regulator | 0.0239 | 0.2341 | 0.2321 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0385 | 0.3952 | 0.3952 |
Schistosoma mansoni | axis inhibition protein axin | 0.0039 | 0.0117 | 0.0091 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.0471 | 0.0446 |
Giardia lamblia | Hypothetical protein | 0.0931 | 1 | 1 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.0471 | 0.0446 |
Trypanosoma brucei | Silent information regulator 2 related protein 3 | 0.0385 | 0.3952 | 0.38 |
Trichomonas vaginalis | Citrate lyase beta chain, putative | 0.0075 | 0.0525 | 0.0525 |
Echinococcus granulosus | NAD dependent deacetylase sirtuin 3 | 0.0931 | 1 | 1 |
Schistosoma mansoni | tyrosinase precursor | 0.009 | 0.0689 | 0.0664 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0039 | 0.0117 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0117 | 0.0091 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0128 | 0.0128 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0075 | 0.0525 | 0.0286 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0406 | 0.0381 |
Leishmania major | silent information regulator 2, putative | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | glutaminase | 0.0559 | 0.5879 | 0.5868 |
Mycobacterium tuberculosis | Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) | 0.0075 | 0.0525 | 0.0752 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.004 | 0.0128 | 0.0101 |
Mycobacterium ulcerans | glutaminase | 0.0559 | 0.5879 | 1 |
Schistosoma mansoni | regulator of G protein signaling | 0.0039 | 0.0117 | 0.0091 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0039 | 0.0117 | 0.0091 |
Loa Loa (eye worm) | tyrosinase 1 | 0.009 | 0.0689 | 0.0664 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.004 | 0.0128 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0689 | 0.0664 |
Toxoplasma gondii | histone deacetylase SIR2-like | 0.0239 | 0.2341 | 0.5896 |
Echinococcus multilocularis | NAD dependent deacetylase sirtuin 1 | 0.0581 | 0.6117 | 0.6106 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0581 | 0.6117 | 0.6117 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0084 | 0.0057 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0931 | 1 | 1 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.009 | 0.0689 | 0.0664 |
Entamoeba histolytica | Sir2 family transcriptional regulator, putative | 0.0385 | 0.3952 | 0.388 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.005 | 0.0246 | 0.022 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0291 | 0.291 | 0.2891 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0655 | 0.6941 | 0.6864 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 0.291 | 0.291 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0039 | 0.0117 | 0.0091 |
Mycobacterium ulcerans | Sir2-like regulatory protein | 0.0239 | 0.2341 | 0.3719 |
Brugia malayi | jmjC domain containing protein | 0.0037 | 0.0098 | 0.0071 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0291 | 0.291 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0084 | 0.0057 |
Brugia malayi | transcriptional regulator, Sir2 family protein | 0.0239 | 0.2341 | 0.2321 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0039 | 0.0117 | 0.0091 |
Entamoeba histolytica | Sir2 family transcriptional regulator, putative | 0.0931 | 1 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0145 | 0.1295 | 0.3232 |
Brugia malayi | Heterochromatin protein 1 | 0.0071 | 0.0471 | 0.0446 |
Schistosoma mansoni | regulator of G protein signaling | 0.0039 | 0.0117 | 0.0091 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0039 | 0.0117 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0117 | 0.0091 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0266 | 0.024 |
Brugia malayi | Thioredoxin reductase | 0.0145 | 0.1295 | 0.1272 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0331 | 0.3352 | 0.8381 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0039 | 0.0117 | 0.0091 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0145 | 0.1295 | 0.1272 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0039 | 0.0117 | 0.0091 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.009 | 0.0689 | 0.0664 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0037 | 0.0099 | 0.0072 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0385 | 0.3952 | 0.3952 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0117 | 0.0091 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0581 | 0.6117 | 0.6106 |
Brugia malayi | chromobox protein homolog 3 | 0.004 | 0.0128 | 0.0101 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0144 | 0.1284 | 0.1284 |
Trypanosoma brucei | polo-like protein kinase | 0.0291 | 0.291 | 0.2731 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0117 | 0.0091 |
Echinococcus multilocularis | NAD dependent deacetylase sirtuin 7 | 0.0239 | 0.2341 | 0.2321 |
Brugia malayi | Common central domain of tyrosinase family protein | 0.009 | 0.0689 | 0.0664 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0071 | 0.0471 | 0.0446 |
Trypanosoma brucei | SIR2-like protein 4, putative | 0.0239 | 0.2341 | 0.2148 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0145 | 0.1295 | 0.1272 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0291 | 0.291 | 0.2731 |
Echinococcus granulosus | chromatin regulatory protein sir2 | 0.0931 | 1 | 1 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.01 | 0.0793 | 0.0769 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0406 | 0.0381 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0931 | 1 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0145 | 0.1295 | 0.3232 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0368 | 0.3761 | 0.9484 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0331 | 0.3352 | 0.8381 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0239 | 0.2341 | 0.2341 |
Schistosoma mansoni | axis inhibition protein axin | 0.0039 | 0.0117 | 0.0091 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.0406 | 0.0381 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0331 | 0.3352 | 0.8381 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0075 | 0.0525 | 0.0495 |
Trypanosoma brucei | trypanothione reductase | 0.0145 | 0.1295 | 0.1076 |
Entamoeba histolytica | Sir2 family transcriptional regulator, putative | 0.0931 | 1 | 1 |
Treponema pallidum | NADH oxidase | 0.005 | 0.0246 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 0.291 | 0.291 |
Brugia malayi | glutaminase DH11.1 | 0.0559 | 0.5879 | 0.5868 |
Giardia lamblia | Sirtuin type 2 | 0.0239 | 0.2341 | 0.2321 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0144 | 0.1284 | 0.1284 |
Schistosoma mansoni | kinase | 0.0148 | 0.1326 | 0.1303 |
Plasmodium falciparum | transcriptional regulatory protein sir2a | 0.0385 | 0.3952 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0331 | 0.3352 | 0.8381 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0039 | 0.0117 | 0.0091 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.005 | 0.0246 | 0.5 |
Loa Loa (eye worm) | glutathione reductase | 0.0145 | 0.1295 | 0.1272 |
Loa Loa (eye worm) | transcriptional regulator | 0.0931 | 1 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0655 | 0.6941 | 0.6864 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0084 | 0.0057 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0581 | 0.6117 | 0.6117 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0039 | 0.0117 | 0.0091 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 0.291 | 0.291 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0037 | 0.0098 | 0.0071 |
Plasmodium falciparum | transcriptional regulatory protein sir2b | 0.0239 | 0.2341 | 0.5896 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.0406 | 0.0381 |
Trypanosoma brucei | Silent information regulator 2 related protein 1 | 0.0931 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.005 | 0.0246 | 0.5 |
Trypanosoma cruzi | Silent information regulator 2 related protein 3 | 0.0385 | 0.3952 | 0.38 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0039 | 0.0117 | 0.0091 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0037 | 0.0098 | 0.0071 |
Trichomonas vaginalis | mercuric reductase, putative | 0.005 | 0.0246 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0266 | 0.024 |
Entamoeba histolytica | NAD-dependent deacetylase 1, putative | 0.0239 | 0.2341 | 0.225 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0075 | 0.0525 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0117 | 0.0091 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.0161 | 0.0161 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0039 | 0.0117 | 0.0091 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.009 | 0.0689 | 0.0664 |
Plasmodium falciparum | glutathione reductase | 0.005 | 0.0246 | 0.0559 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.005 | 0.0246 | 0.0559 |
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.0406 | 0.0381 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.0406 | 0.0381 |
Loa Loa (eye worm) | transcriptional regulator | 0.0239 | 0.2341 | 0.2321 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.005 | 0.0246 | 0.0559 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0145 | 0.1295 | 0.2831 |
Schistosoma mansoni | jumonji domain containing protein | 0.0079 | 0.0567 | 0.0541 |
Plasmodium vivax | NAD-dependent deacetylase, putative | 0.0385 | 0.3952 | 1 |
Echinococcus granulosus | expressed protein | 0.0752 | 0.8014 | 0.8009 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 0.291 | 0.291 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0039 | 0.0117 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0581 | 0.6117 | 0.6106 |
Giardia lamblia | NAD-dependent histone deacetylase Sir2 | 0.0581 | 0.6117 | 0.6106 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0239 | 0.2341 | 0.225 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0039 | 0.0117 | 0.0091 |
Schistosoma mansoni | regulator of G protein signaling | 0.0039 | 0.0117 | 0.0091 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.0161 | 0.0466 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0239 | 0.2341 | 0.2321 |
Onchocerca volvulus | 0.009 | 0.0689 | 0.2296 | |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0039 | 0.0117 | 0.0091 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.005 | 0.0246 | 0.0559 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.