Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.01 | 0.047 | 0.0462 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0106 | 0.0503 | 0.1204 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0113 | 0.0543 | 0.0738 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0106 | 0.0503 | 0.9236 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0055 | 0.086 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.01 | 0.0471 | 0.1145 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0074 | 0.018 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0309 | 0.5702 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0027 | 0.0056 | 0.0874 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0113 | 0.0543 | 0.1303 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0025 | 0.0041 | 0.0605 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0025 | 0.0041 | 0.0605 |
Plasmodium vivax | hypothetical protein, conserved | 0.0113 | 0.0543 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0037 | 0.0111 | 0.0269 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0031 | 0.0074 | 0.0159 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0055 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0055 | 0.0112 |
Giardia lamblia | Kinase, PLK | 0.0111 | 0.0534 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0543 | 0.1303 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0113 | 0.0543 | 0.0738 |
Onchocerca volvulus | 0.0151 | 0.0758 | 1 | |
Onchocerca volvulus | 0.0113 | 0.0543 | 0.6857 | |
Trichomonas vaginalis | esterase, putative | 0.0113 | 0.0543 | 1 |
Echinococcus multilocularis | peregrin | 0.0031 | 0.0074 | 0.0065 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0113 | 0.0543 | 0.0738 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.0916 | 0.2433 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0025 | 0.0041 | 0.0079 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.0309 | 0.0803 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0146 | 0.0732 | 0.0724 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.0732 | 0.194 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0106 | 0.0503 | 0.0494 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0543 | 0.1303 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0106 | 0.0503 | 0.9236 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0113 | 0.0543 | 0.1433 |
Mycobacterium tuberculosis | Arylamine N-acetyltransferase Nat (arylamine acetylase) | 0.129 | 0.7246 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0072 | 0.0309 | 0.03 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0111 | 0.0534 | 0.9834 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.0219 | 0.021 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0034 | 0.0092 | 0.1554 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0146 | 0.0732 | 0.1783 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0145 | 0.0331 |
Leishmania major | importin beta-1 subunit, putative | 0.0027 | 0.0056 | 0.0874 |
Giardia lamblia | PHD finger protein 15 | 0.0031 | 0.0074 | 0.1239 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0543 | 0.1303 |
Brugia malayi | hypothetical protein | 0.0739 | 0.4109 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0106 | 0.0503 | 0.9236 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0113 | 0.0543 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0739 | 0.4109 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0111 | 0.0534 | 0.9834 |
Schistosoma mansoni | importin beta-1 | 0.0034 | 0.0092 | 0.0223 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0111 | 0.0534 | 0.9834 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0111 | 0.0534 | 0.0526 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0543 | 0.1303 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.01 | 0.0471 | 0.1126 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0106 | 0.0503 | 0.1323 |
Leishmania major | GTP-binding protein, putative | 0.0025 | 0.0041 | 0.0605 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0055 | 0.5534 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0106 | 0.0503 | 0.9236 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.0219 | 0.029 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0025 | 0.0041 | 0.0615 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0106 | 0.0503 | 0.1204 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0113 | 0.0543 | 0.1322 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0106 | 0.0503 | 0.9236 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.02 | 0.0466 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0309 | 0.5702 |
Echinococcus granulosus | expressed conserved protein | 0.0094 | 0.0436 | 0.1042 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0102 | 0.0479 | 0.1262 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0043 | 0.0145 | 0.0331 |
Leishmania major | hypothetical protein, conserved | 0.0113 | 0.0543 | 1 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0052 | 0.0198 | 0.046 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0025 | 0.0041 | 0.0605 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0055 | 0.086 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0009 | 0.0022 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0031 | 0.0074 | 0.0065 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0146 | 0.0732 | 0.0724 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.0916 | 0.2433 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0471 | 0.1126 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0113 | 0.0543 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.01 | 0.0471 | 0.0462 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0111 | 0.0273 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0674 | 0.3738 | 0.3732 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.01 | 0.0471 | 0.8785 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0111 | 0.0534 | 0.1282 |
Brugia malayi | MAP kinase sur-1 | 0.0106 | 0.0503 | 0.1223 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0106 | 0.0503 | 0.0494 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0113 | 0.0543 | 0.0738 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0111 | 0.0534 | 0.9834 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0043 | 0.0145 | 0.0331 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0198 | 0.0462 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0136 | 0.0341 |
Echinococcus multilocularis | expressed conserved protein | 0.0094 | 0.0436 | 0.0427 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0111 | 0.0534 | 0.1409 |
Entamoeba histolytica | Ran family GTPase | 0.0025 | 0.0041 | 0.0615 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0009 | 0.5 |
Mycobacterium ulcerans | lipase LipD | 0.0113 | 0.0543 | 0.0738 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0056 | 0.0219 | 0.0563 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0113 | 0.0543 | 0.0738 |
Mycobacterium leprae | conserved hypothetical protein | 0.0113 | 0.0543 | 0.5 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0106 | 0.0503 | 0.9392 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.036 | 0.195 | 0.4734 |
Plasmodium falciparum | phd finger protein, putative | 0.0031 | 0.0074 | 0.7841 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0037 | 0.0111 | 0.0248 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0037 | 0.0111 | 0.0248 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0674 | 0.3738 | 0.9096 |
Schistosoma mansoni | hypothetical protein | 0.0151 | 0.0758 | 0.201 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0025 | 0.0041 | 0.0079 |
Trypanosoma brucei | polo-like protein kinase | 0.0111 | 0.0534 | 0.9834 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0056 | 0.0219 | 0.0533 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0106 | 0.0503 | 0.9236 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0025 | 0.0041 | 0.0101 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0136 | 0.0341 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0113 | 0.0543 | 0.0738 |
Trypanosoma brucei | protein kinase, putative | 0.0106 | 0.0503 | 0.9236 |
Plasmodium vivax | importin-beta 2, putative | 0.0034 | 0.0092 | 0.1554 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0074 | 0.0175 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.0564 | 0.1373 |
Echinococcus multilocularis | snurportin 1 | 0.036 | 0.195 | 0.1943 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0113 | 0.0543 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 0.0543 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0037 | 0.0111 | 0.0102 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0113 | 0.0543 | 0.0535 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 0.0543 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0009 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0111 | 0.0534 | 0.9834 |
Echinococcus granulosus | geminin | 0.0179 | 0.0916 | 0.2213 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0027 | 0.0056 | 0.0874 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0106 | 0.0503 | 0.9236 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0111 | 0.0534 | 0.1301 |
Loa Loa (eye worm) | beta-lactamase | 0.0113 | 0.0543 | 0.1303 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0111 | 0.0534 | 0.9834 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0146 | 0.0732 | 0.1765 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0543 | 0.1303 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0106 | 0.0503 | 0.9236 |
Brugia malayi | Bromodomain containing protein | 0.0031 | 0.0074 | 0.018 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.0564 | 0.1354 |
Mycobacterium ulcerans | hypothetical protein | 0.0113 | 0.0543 | 0.0738 |
Onchocerca volvulus | 0.0113 | 0.0543 | 0.6857 | |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.0219 | 0.0512 |
Brugia malayi | beta-lactamase family protein | 0.0113 | 0.0543 | 0.1322 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.0074 | 0.1218 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0034 | 0.0092 | 0.0083 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0309 | 0.5702 |
Schistosoma mansoni | patched 1 | 0.0043 | 0.0145 | 0.0364 |
Echinococcus granulosus | snurportin 1 | 0.036 | 0.195 | 0.4734 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0106 | 0.0503 | 0.9236 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0055 | 0.086 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0739 | 0.4109 | 0.4103 |
Mycobacterium tuberculosis | Conserved protein | 0.0113 | 0.0543 | 0.0738 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0309 | 0.5702 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0027 | 0.0056 | 0.0874 |
Plasmodium falciparum | importin beta, putative | 0.0034 | 0.0092 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0113 | 0.0543 | 0.0738 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0106 | 0.0503 | 0.9236 |
Brugia malayi | RNA, U transporter 1 | 0.0096 | 0.0446 | 0.1086 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0722 | 0.401 | 0.5529 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0145 | 0.2543 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0143 | 0.0715 | 0.0707 |
Echinococcus multilocularis | protein dispatched 1 | 0.0049 | 0.0179 | 0.0171 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0113 | 0.0543 | 0.1303 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0136 | 0.0341 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0056 | 0.0889 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0113 | 0.0543 | 0.0738 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0106 | 0.0503 | 0.1204 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0111 | 0.0534 | 0.6727 |
Echinococcus granulosus | jumonji domain containing protein | 0.0043 | 0.0142 | 0.0325 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.0732 | 0.194 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0113 | 0.0543 | 0.0738 |
Schistosoma mansoni | ran | 0.0025 | 0.0041 | 0.0087 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0056 | 0.0217 | 0.3889 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0111 | 0.0534 | 0.9834 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0043 | 0.0145 | 0.0136 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0113 | 0.0543 | 0.0738 |
Schistosoma mansoni | survival motor neuron protein | 0.0151 | 0.0758 | 0.201 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0043 | 0.0142 | 0.0133 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0113 | 0.0543 | 1 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0111 | 0.0534 | 0.9834 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0034 | 0.0092 | 0.1554 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0025 | 0.0041 | 0.0605 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0031 | 0.0074 | 0.0175 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0055 | 0.086 |
Brugia malayi | jmjC domain containing protein | 0.01 | 0.047 | 0.1144 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0113 | 0.0543 | 0.1433 |
Mycobacterium leprae | Probable lipase LipE | 0.0113 | 0.0543 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.036 | 0.195 | 0.5205 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0074 | 0.1218 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0074 | 0.0159 |
Mycobacterium tuberculosis | Conserved protein | 0.0113 | 0.0543 | 0.0738 |
Onchocerca volvulus | 0.0113 | 0.0543 | 0.6857 | |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0111 | 0.0273 |
Brugia malayi | beta-lactamase | 0.0113 | 0.0543 | 0.1322 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0151 | 0.0758 | 0.1846 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0146 | 0.0732 | 0.1765 |
Echinococcus granulosus | importin subunit beta 1 | 0.0034 | 0.0092 | 0.0203 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0034 | 0.0092 | 0.1554 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0543 | 0.1303 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0031 | 0.0074 | 0.0159 |
Schistosoma mansoni | jumonji domain containing protein | 0.008 | 0.0353 | 0.0922 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0111 | 0.0534 | 0.9834 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.01 | 0.047 | 0.1125 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0056 | 0.0219 | 0.3931 |
Trichomonas vaginalis | importin beta-1, putative | 0.0027 | 0.0056 | 0.0874 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0056 | 0.0217 | 0.3889 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.0219 | 0.029 |
Brugia malayi | Importin beta-1 subunit | 0.0034 | 0.0092 | 0.0224 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0025 | 0.0041 | 0.0032 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0055 | 0.5534 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0146 | 0.0732 | 0.1765 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0674 | 0.3738 | 1 |
Echinococcus multilocularis | geminin | 0.0179 | 0.0916 | 0.0908 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0113 | 0.0543 | 1 |
Schistosoma mansoni | kinase | 0.0057 | 0.0225 | 0.058 |
Loa Loa (eye worm) | hypothetical protein | 0.0739 | 0.4109 | 1 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0043 | 0.0145 | 0.0331 |
Toxoplasma gondii | ABC1 family protein | 0.0113 | 0.0543 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0106 | 0.0503 | 0.9236 |
Brugia malayi | hypothetical protein | 0.0072 | 0.0309 | 0.0751 |
Trichomonas vaginalis | ran, putative | 0.0025 | 0.0041 | 0.0605 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0113 | 0.0543 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0106 | 0.0503 | 0.9236 |
Echinococcus multilocularis | protein patched | 0.0043 | 0.0145 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0092 | 0.0203 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0111 | 0.0534 | 0.9834 |
Brugia malayi | CHE-14 protein | 0.0043 | 0.0145 | 0.0353 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.0564 | 0.1354 |
Echinococcus granulosus | peregrin | 0.0031 | 0.0074 | 0.0159 |
Schistosoma mansoni | ran | 0.0025 | 0.0041 | 0.0087 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0025 | 0.0041 | 0.3893 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0063 | 0.0259 | 0.0611 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0136 | 0.0341 |
Mycobacterium ulcerans | arylamine N-acetyltransferase Nat | 0.129 | 0.7246 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0143 | 0.0715 | 0.1723 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0111 | 0.0534 | 0.1282 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.0732 | 0.194 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0055 | 0.086 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0072 | 0.0309 | 0.0803 |
Brugia malayi | beta-lactamase family protein | 0.0113 | 0.0543 | 0.1322 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0074 | 0.1218 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0025 | 0.0041 | 0.0605 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0072 | 0.0309 | 0.0731 |
Mycobacterium ulcerans | beta-lactamase | 0.0113 | 0.0543 | 0.0738 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0055 | 0.086 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 0.0219 | 0.029 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0111 | 0.0534 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.