Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | ETS transcription factor Elf 5 | 0.001 | 0.0019 | 0.0017 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0053 | 0.0653 | 0.856 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.0655 | 0.2116 |
Echinococcus granulosus | ETS domain containing protein Elk 1 | 0.001 | 0.0019 | 0.0017 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0045 | 0.0543 | 0.1757 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0157 | 0.1548 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0071 | 0.0928 | 0.0926 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.0157 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0423 | 0.6188 | 0.6181 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0157 | 0.1548 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.001 | 0.0019 | 0.0055 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0405 | 0.0387 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0157 | 0.0508 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.0806 | 0.0789 |
Loa Loa (eye worm) | fli-1 protein | 0.0216 | 0.3094 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0157 | 0.1548 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0045 | 0.0543 | 0.7789 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0114 | 0.037 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0334 | 0.0332 |
Echinococcus granulosus | dna polymerase eta | 0.0045 | 0.0543 | 0.0542 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0053 | 0.0653 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.0655 | 0.2111 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0157 | 0.1548 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0157 | 0.1548 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0114 | 0.0096 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0655 | 0.2111 |
Brugia malayi | Ets-domain containing protein | 0.001 | 0.0019 | 0.006 |
Echinococcus multilocularis | ETS transcription factor Elf 1 | 0.001 | 0.0019 | 0.0017 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0114 | 0.0113 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0374 | 0.1208 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.0308 | 0.0992 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0114 | 0.0113 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0157 | 0.0139 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0071 | 0.0928 | 0.0926 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0157 | 0.0155 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0157 | 0.1548 |
Brugia malayi | DNA-binding protein D-ETS-3 | 0.001 | 0.0019 | 0.006 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0218 | 0.02 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0334 | 0.0332 |
Echinococcus multilocularis | ets variant gene 4 | 0.001 | 0.0019 | 0.0017 |
Leishmania major | DNA polymerase eta, putative | 0.0045 | 0.0543 | 0.7789 |
Leishmania major | DNA polymerase eta, putative | 0.0032 | 0.0342 | 0.3719 |
Brugia malayi | Fli-1 protein | 0.0216 | 0.3094 | 1 |
Brugia malayi | transcription factor E74 isoform | 0.001 | 0.0019 | 0.006 |
Echinococcus granulosus | protein C ets 2 | 0.001 | 0.0019 | 0.0017 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.0157 | 0.5 |
Loa Loa (eye worm) | D-ets-2 protein | 0.001 | 0.0019 | 0.0055 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.001 | 0.0019 | 0.0017 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0114 | 0.0113 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.0308 | 0.0997 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0157 | 0.1548 |
Brugia malayi | Ets-domain containing protein | 0.0071 | 0.0928 | 0.3 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0157 | 0.1548 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0114 | 0.0113 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0157 | 0.1548 |
Echinococcus multilocularis | dna polymerase eta | 0.0045 | 0.0543 | 0.0542 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0114 | 0.0364 |
Mycobacterium tuberculosis | Arylamine N-acetyltransferase Nat (arylamine acetylase) | 0.0642 | 0.945 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0114 | 0.0096 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0053 | 0.0653 | 0.5 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0423 | 0.6188 | 0.6187 |
Echinococcus granulosus | ETS transcription factor Elf 5 | 0.001 | 0.0019 | 0.0017 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0157 | 0.0502 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0032 | 0.0342 | 0.3719 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0114 | 0.0113 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.001 | 0.0019 | 0.0017 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0157 | 0.0139 |
Echinococcus granulosus | dnaJ subfamily B | 0.0423 | 0.6188 | 0.6187 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0.0157 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0053 | 0.0653 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0334 | 0.0316 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0056 | 0.0706 | 1 |
Echinococcus granulosus | ewsr:fli fusion protein type | 0.001 | 0.0019 | 0.0017 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0679 | 1 | 1 |
Onchocerca volvulus | 0.003 | 0.0308 | 0.5 | |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0114 | 0.037 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0019 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0405 | 0.1303 |
Loa Loa (eye worm) | DNA-binding protein D-ETS-3 | 0.001 | 0.0019 | 0.0055 |
Echinococcus multilocularis | protein C ets 2 | 0.001 | 0.0019 | 0.0017 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0045 | 0.0543 | 0.8131 |
Mycobacterium ulcerans | arylamine N-acetyltransferase Nat | 0.0642 | 0.945 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0157 | 0.1548 |
Echinococcus granulosus | ETS transcription factor Elf 1 | 0.001 | 0.0019 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0114 | 0.0364 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0334 | 0.0316 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0157 | 0.0155 |
Echinococcus multilocularis | ETS domain containing protein Elk 1 | 0.001 | 0.0019 | 0.0017 |
Echinococcus granulosus | geminin | 0.0346 | 0.5039 | 0.5038 |
Schistosoma mansoni | gabp alpha | 0.0071 | 0.0928 | 0.0911 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.001 | 0.0019 | 0.0017 |
Schistosoma mansoni | hypothetical protein | 0.0346 | 0.5039 | 0.503 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0053 | 0.0653 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0405 | 0.1308 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0157 | 0.1548 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0071 | 0.0928 | 0.2996 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.0655 | 0.2116 |
Brugia malayi | Ets-domain containing protein | 0.0071 | 0.0928 | 0.3 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0053 | 0.0653 | 0.5 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0024 | 0.0218 | 0.0216 |
Loa Loa (eye worm) | ets-domain-containing protein | 0.001 | 0.0019 | 0.0055 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0157 | 0.1548 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.0157 | 0.5 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0157 | 0.0155 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0157 | 0.1548 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0114 | 0.0096 |
Schistosoma mansoni | ets-related | 0.0216 | 0.3094 | 0.3081 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0053 | 0.0653 | 1 |
Echinococcus multilocularis | ewsr:fli fusion protein type | 0.001 | 0.0019 | 0.0017 |
Schistosoma mansoni | DNA polymerase eta | 0.0045 | 0.0543 | 0.0526 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0024 | 0.0218 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0019 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0774 | 0.2497 |
Echinococcus multilocularis | geminin | 0.0346 | 0.5039 | 0.5038 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0114 | 0.0113 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0157 | 0.1548 |
Schistosoma mansoni | hypothetical protein | 0.0346 | 0.5039 | 0.503 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0653 | 0.2107 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0053 | 0.0653 | 1 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.001 | 0.0019 | 0.0017 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0114 | 0.0096 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0543 | 0.1752 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0679 | 1 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0308 | 0.029 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0157 | 0.0155 |
Brugia malayi | hypothetical protein | 0.0053 | 0.0653 | 0.2111 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.