Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.0756 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0264 | 0.2688 | 1 |
Onchocerca volvulus | 0.0084 | 0 | 0.5 | |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0084 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0264 | 0.2688 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0264 | 0.2688 | 0.2688 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0084 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0756 | 1 | 1 |
Onchocerca volvulus | 0.0084 | 0 | 0.5 | |
Plasmodium vivax | vivapain-3 | 0.0084 | 0 | 0.5 |
Plasmodium vivax | unspecified product | 0.0084 | 0 | 0.5 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0756 | 1 | 1 |
Onchocerca volvulus | 0.0084 | 0 | 0.5 | |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0084 | 0 | 0.5 |
Onchocerca volvulus | 0.0084 | 0 | 0.5 | |
Echinococcus granulosus | cathepsin b | 0.0756 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0264 | 0.2688 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0084 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0756 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Toxoplasma gondii | cathepsin B | 0.0264 | 0.2688 | 1 |
Onchocerca volvulus | 0.0084 | 0 | 0.5 | |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Onchocerca volvulus | 0.0084 | 0 | 0.5 | |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0264 | 0.2688 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0084 | 0 | 0.5 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0264 | 0.2688 | 1 |
Plasmodium vivax | vivapain-1 | 0.0084 | 0 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0264 | 0.2688 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0756 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Echinococcus multilocularis | cathepsin b | 0.0756 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0756 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0084 | 0 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0756 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0084 | 0 | 0.5 |
Onchocerca volvulus | 0.0084 | 0 | 0.5 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0084 | 0 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0084 | 0 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0264 | 0.2688 | 0.2688 |
Loa Loa (eye worm) | hypothetical protein | 0.0756 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0084 | 0 | 0.5 |
Loa Loa (eye worm) | cathepsin B | 0.0264 | 0.2688 | 0.2688 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.