Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0047 | 0 | 0.5 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0425 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0047 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0149 | 0.2688 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0149 | 0.2688 | 0.2688 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0047 | 0 | 0.5 |
Onchocerca volvulus | 0.0047 | 0 | 0.5 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0149 | 0.2688 | 1 |
Echinococcus granulosus | cathepsin b | 0.0425 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0047 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0047 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0047 | 0 | 0.5 |
Toxoplasma gondii | cathepsin B | 0.0149 | 0.2688 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0047 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0425 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0047 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0149 | 0.2688 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.0425 | 1 | 1 |
Onchocerca volvulus | 0.0047 | 0 | 0.5 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0047 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0047 | 0 | 0.5 |
Onchocerca volvulus | 0.0047 | 0 | 0.5 | |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0425 | 1 | 1 |
Plasmodium vivax | unspecified product | 0.0047 | 0 | 0.5 |
Plasmodium vivax | vivapain-3 | 0.0047 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0149 | 0.2688 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0047 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0047 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0047 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0047 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0047 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0047 | 0 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0047 | 0 | 0.5 |
Plasmodium vivax | vivapain-1 | 0.0047 | 0 | 0.5 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0149 | 0.2688 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0149 | 0.2688 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0047 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0047 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0047 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0047 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0047 | 0 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0047 | 0 | 0.5 |
Onchocerca volvulus | 0.0047 | 0 | 0.5 | |
Onchocerca volvulus | 0.0047 | 0 | 0.5 | |
Entamoeba histolytica | cysteine protease, putative | 0.0047 | 0 | 0.5 |
Loa Loa (eye worm) | cathepsin B | 0.0149 | 0.2688 | 0.2688 |
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0047 | 0 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0149 | 0.2688 | 0.2688 |
Plasmodium vivax | vivapain-2 | 0.0047 | 0 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0047 | 0 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0047 | 0 | 0.5 |
Onchocerca volvulus | 0.0047 | 0 | 0.5 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0425 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0047 | 0 | 0.5 |
Onchocerca volvulus | Cathepsin F homolog | 0.0047 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0047 | 0 | 0.5 |
Echinococcus multilocularis | cathepsin b | 0.0425 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0425 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0047 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0425 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.