Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.1674 | 0.7606 | 0.7255 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1674 | 0.7606 | 0.7606 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0416 | 0.128 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0416 | 0.128 | 1 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.215 | 1 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.1778 | 0.8131 | 0.8118 |
Trypanosoma brucei | glucosidase, putative | 0.0416 | 0.128 | 1 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0975 | 0.4089 | 0.5 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.215 | 1 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.1828 | 0.8378 | 0.8378 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.1778 | 0.8131 | 0.8118 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0416 | 0.128 | 0.1501 |
Schistosoma mansoni | alpha glucosidase | 0.0416 | 0.128 | 0.128 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.2068 | 0.9589 | 0.9586 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1778 | 0.8131 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0416 | 0.128 | 0.1501 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1167 | 0.5055 | 0.6185 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.2068 | 0.9589 | 0.9528 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1167 | 0.5055 | 0.6185 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0416 | 0.128 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1167 | 0.5055 | 0.6185 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1167 | 0.5055 | 0.6185 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.123 | 0.5371 | 0.6577 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0416 | 0.128 | 0.1501 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1778 | 0.8131 | 1 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.1674 | 0.7606 | 0.7255 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0416 | 0.128 | 0.1501 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1778 | 0.8131 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1778 | 0.8131 | 1 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.1674 | 0.7606 | 0.7255 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0416 | 0.128 | 0.1501 |
Schistosoma mansoni | alpha-glucosidase | 0.1828 | 0.8378 | 0.8378 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0416 | 0.128 | 0.1501 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0416 | 0.128 | 0.1219 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1778 | 0.8131 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1167 | 0.5055 | 0.6185 |
Loa Loa (eye worm) | hypothetical protein | 0.113 | 0.487 | 0.4834 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.2068 | 0.9589 | 0.9528 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1674 | 0.7606 | 0.7606 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0416 | 0.128 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1778 | 0.8131 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.2068 | 0.9589 | 0.9528 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0416 | 0.128 | 1 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.215 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.123 | 0.5371 | 0.6577 |
Onchocerca volvulus | 0.1228 | 0.5363 | 0.5331 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1167 | 0.5055 | 0.6185 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.215 | 1 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0416 | 0.128 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0416 | 0.128 | 0.1219 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.215 | 1 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.2068 | 0.9589 | 0.9586 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0416 | 0.128 | 0.1501 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0416 | 0.128 | 0.1501 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.1167 | 0.5055 | 0.5021 |
Echinococcus granulosus | bile acid beta glucosidase | 0.1674 | 0.7606 | 0.7255 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.215 | 1 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0416 | 0.128 | 0.1501 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1167 | 0.5055 | 0.6185 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.