Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | ceramide glucosyltransferase | 0.1751 | 1 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.1446 | 0.8068 | 0.8035 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0794 | 0.3923 | 0.5 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0274 | 0.0625 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0274 | 0.0625 | 0.5 |
Schistosoma mansoni | alpha glucosidase | 0.0274 | 0.0625 | 0.0625 |
Schistosoma mansoni | alpha-glucosidase | 0.1296 | 0.7116 | 0.7116 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1308 | 0.7188 | 0.7188 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.1446 | 0.8068 | 0.8035 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1623 | 0.9188 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0274 | 0.0625 | 0.0465 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1623 | 0.9188 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0883 | 0.4489 | 0.4395 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.1308 | 0.7188 | 0.714 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1623 | 0.9188 | 1 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.1751 | 1 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0274 | 0.0625 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1122 | 0.6008 | 0.6287 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0274 | 0.0625 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1065 | 0.5644 | 0.5862 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1065 | 0.5644 | 0.5862 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1065 | 0.5644 | 0.5862 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0274 | 0.0625 | 0.0465 |
Schistosoma mansoni | alpha-glucosidase | 0.1296 | 0.7116 | 0.7116 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1446 | 0.8068 | 0.8035 |
Schistosoma mansoni | peroxidasin | 0.0202 | 0.0168 | 0.0168 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1446 | 0.8068 | 0.8035 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1308 | 0.7188 | 0.7188 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.1446 | 0.8068 | 0.8035 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.1623 | 0.9188 | 0.9174 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1065 | 0.5644 | 0.5862 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0274 | 0.0625 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0274 | 0.0625 | 0.5 |
Onchocerca volvulus | 0.0871 | 0.4415 | 0.432 | |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.1623 | 0.9188 | 0.9174 |
Echinococcus granulosus | bile acid beta glucosidase | 0.1308 | 0.7188 | 0.714 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1623 | 0.9188 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1122 | 0.6008 | 0.6287 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.1751 | 1 | 1 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0274 | 0.0625 | 0.0465 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0274 | 0.0625 | 0.0465 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.1751 | 1 | 1 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.1065 | 0.5644 | 0.557 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1065 | 0.5644 | 0.5862 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.1308 | 0.7188 | 0.714 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1623 | 0.9188 | 1 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.1308 | 0.7188 | 0.714 |
Schistosoma mansoni | peroxidasin | 0.0202 | 0.0168 | 0.0168 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1623 | 0.9188 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1065 | 0.5644 | 0.5862 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.1751 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1065 | 0.5644 | 0.5862 |
Trypanosoma brucei | glucosidase, putative | 0.0274 | 0.0625 | 0.5 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.1751 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.