Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.105 | 0.8331 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.101 | 0.7965 | 0.7886 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0198 | 0.0512 | 0.0614 |
Onchocerca volvulus | 0.0679 | 0.4924 | 0.4631 | |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Echinococcus granulosus | bile acid beta glucosidase | 0.0846 | 0.6461 | 0.6461 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.0846 | 0.6461 | 0.6461 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Brugia malayi | Animal haem peroxidase family protein | 0.0202 | 0.0545 | 0.0545 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0198 | 0.0512 | 0.0614 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0198 | 0.0512 | 0.0512 |
Brugia malayi | Blistered cuticle protein 3 | 0.0202 | 0.0545 | 0.0545 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.105 | 0.8331 | 1 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.1232 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0198 | 0.0512 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.105 | 0.8331 | 1 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0202 | 0.0545 | 0.0545 |
Brugia malayi | Peroxidasin | 0.0202 | 0.0545 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Brugia malayi | Animal haem peroxidase family protein | 0.0202 | 0.0545 | 0.0545 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0198 | 0.0512 | 0.0512 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0689 | 0.5017 | 0.6022 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0198 | 0.0512 | 0.0512 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0689 | 0.5017 | 0.6022 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0726 | 0.5357 | 0.6431 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0198 | 0.0512 | 0.0614 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0198 | 0.0512 | 1 |
Schistosoma mansoni | peroxidasin | 0.0202 | 0.0545 | 0.0179 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0198 | 0.0512 | 0.0512 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0202 | 0.0545 | 0.0545 |
Echinococcus granulosus | peroxidasin | 0.0202 | 0.0545 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0202 | 0.0545 | 0.0545 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.105 | 0.8331 | 0.8331 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0198 | 0.0512 | 0.5 |
Echinococcus multilocularis | peroxidasin | 0.0202 | 0.0545 | 0.0545 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.1232 | 1 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0198 | 0.0512 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0689 | 0.5017 | 0.6022 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1111 | 0.8893 | 0.8893 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.0846 | 0.6461 | 0.6461 |
Schistosoma mansoni | alpha glucosidase | 0.0198 | 0.0512 | 0.0144 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0198 | 0.0512 | 0.0614 |
Schistosoma mansoni | alpha-glucosidase | 0.101 | 0.7965 | 0.7886 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0689 | 0.5017 | 0.6022 |
Brugia malayi | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.1232 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0202 | 0.0545 | 0.0545 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.1232 | 1 | 1 |
Trypanosoma brucei | glucosidase, putative | 0.0198 | 0.0512 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0198 | 0.0512 | 1 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.1232 | 1 | 1 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0198 | 0.0512 | 0.0614 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1111 | 0.8893 | 0.8893 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.1111 | 0.8893 | 0.8893 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.105 | 0.8331 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0558 | 0.3819 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.105 | 0.8331 | 1 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0198 | 0.0512 | 0.0614 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.0846 | 0.6461 | 0.6461 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0198 | 0.0512 | 0.0614 |
Brugia malayi | Animal haem peroxidase family protein | 0.0202 | 0.0545 | 0.0545 |
Brugia malayi | Animal haem peroxidase family protein | 0.0202 | 0.0545 | 0.0545 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0198 | 0.0512 | 0.0614 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.105 | 0.8331 | 0.8331 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0846 | 0.6461 | 0.6324 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0202 | 0.0545 | 0.0545 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0689 | 0.5017 | 0.6022 |
Schistosoma mansoni | peroxidasin | 0.0202 | 0.0545 | 0.0179 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0846 | 0.6461 | 0.6324 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.1111 | 0.8893 | 0.8893 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.105 | 0.8331 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0571 | 0.3937 | 0.3937 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0689 | 0.5017 | 0.6022 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.1232 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0689 | 0.5017 | 0.473 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.0545 | 0.0545 |
Brugia malayi | Animal haem peroxidase family protein | 0.0202 | 0.0545 | 0.0545 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0198 | 0.0512 | 0.0614 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.1111 | 0.8893 | 0.8893 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0689 | 0.5017 | 0.6022 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0198 | 0.0512 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0726 | 0.5357 | 0.6431 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.