Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | peroxidasin | 0.0168 | 0.0239 | 0.0071 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0779 | 0.7479 | 1 |
Schistosoma mansoni | hypothetical protein | 0.019 | 0.0501 | 0.0337 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0168 | 0.0239 | 0.0239 |
Brugia malayi | Blistered cuticle protein 3 | 0.0168 | 0.0239 | 0.0239 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0162 | 0.0169 | 0.0169 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0162 | 0.0169 | 0.0169 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0162 | 0.0169 | 0.0226 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0779 | 0.7479 | 0.7479 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.0991 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Brugia malayi | Animal haem peroxidase family protein | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0538 | 0.4631 | 0.6192 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0991 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0162 | 0.0169 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0168 | 0.0239 | 0.0239 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0991 | 1 | 1 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.0628 | 0.5688 | 0.5688 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0168 | 0.0239 | 0.0239 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0162 | 0.0169 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0511 | 0.4304 | 0.5755 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0957 | 0.9598 | 0.9598 |
Schistosoma mansoni | peroxidasin | 0.0168 | 0.0239 | 0.0071 |
Echinococcus multilocularis | peroxidasin | 0.0168 | 0.0239 | 0.0239 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.0628 | 0.5688 | 0.5688 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.0628 | 0.5688 | 0.5688 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0162 | 0.0169 | 0.0169 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0162 | 0.0169 | 0.0226 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.0991 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0779 | 0.7479 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0162 | 0.0169 | 0.0226 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0779 | 0.7479 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.088 | 0.8678 | 0.8655 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0511 | 0.4304 | 0.4165 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Trypanosoma brucei | glucosidase, putative | 0.0162 | 0.0169 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0511 | 0.4304 | 0.5755 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0511 | 0.4304 | 0.5755 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0538 | 0.4631 | 0.6192 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0162 | 0.0169 | 0.5 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0162 | 0.0169 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0779 | 0.7479 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0162 | 0.0169 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0162 | 0.0169 | 0.0226 |
Echinococcus granulosus | peroxidasin | 0.0168 | 0.0239 | 0.0239 |
Schistosoma mansoni | alpha-glucosidase | 0.088 | 0.8678 | 0.8655 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0449 | 0.3575 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0511 | 0.4304 | 0.5755 |
Brugia malayi | Peroxidasin | 0.0168 | 0.0239 | 0.0239 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0628 | 0.5688 | 0.5613 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0957 | 0.9598 | 0.9598 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0957 | 0.9598 | 0.9598 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0162 | 0.0169 | 0.0226 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0162 | 0.0169 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0511 | 0.4304 | 0.5755 |
Onchocerca volvulus | 0.0591 | 0.5256 | 0.514 | |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.0991 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0511 | 0.4304 | 0.5755 |
Brugia malayi | Animal haem peroxidase family protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0424 | 0.327 | 0.327 |
Brugia malayi | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0162 | 0.0169 | 0.0169 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0162 | 0.0169 | 0.0226 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.0991 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0957 | 0.9598 | 0.9598 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0779 | 0.7479 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0957 | 0.9598 | 0.9598 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0511 | 0.4304 | 0.5755 |
Echinococcus granulosus | bile acid beta glucosidase | 0.0628 | 0.5688 | 0.5688 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0779 | 0.7479 | 1 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0162 | 0.0169 | 0.0226 |
Brugia malayi | Animal haem peroxidase family protein | 0.0168 | 0.0239 | 0.0239 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0162 | 0.0169 | 0.0226 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0162 | 0.0169 | 0.0226 |
Brugia malayi | Animal haem peroxidase family protein | 0.0168 | 0.0239 | 0.0239 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0168 | 0.0239 | 0.0239 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0779 | 0.7479 | 0.7479 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0628 | 0.5688 | 0.5613 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.