Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.028 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0031 | 0 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0031 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.028 | 1 | 1 |
Onchocerca volvulus | 0.0031 | 0 | 0.5 | |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0031 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0098 | 0.2688 | 1 |
Onchocerca volvulus | 0.0031 | 0 | 0.5 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0098 | 0.2688 | 0.2688 |
Giardia lamblia | Cathepsin B precursor | 0.0098 | 0.2688 | 0.5 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.028 | 1 | 1 |
Onchocerca volvulus | 0.0031 | 0 | 0.5 | |
Plasmodium vivax | vivapain-3 | 0.0031 | 0 | 0.5 |
Plasmodium vivax | unspecified product | 0.0031 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0031 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.028 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0 | 0.5 |
Toxoplasma gondii | cathepsin B | 0.0098 | 0.2688 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0031 | 0 | 0.5 |
Onchocerca volvulus | 0.0031 | 0 | 0.5 | |
Giardia lamblia | Cathepsin B precursor | 0.0098 | 0.2688 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.028 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0031 | 0 | 0.5 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0098 | 0.2688 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0 | 0.5 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0098 | 0.2688 | 1 |
Plasmodium vivax | vivapain-2 | 0.0031 | 0 | 0.5 |
Plasmodium vivax | vivapain-1 | 0.0031 | 0 | 0.5 |
Onchocerca volvulus | 0.0031 | 0 | 0.5 | |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0 | 0.5 |
Onchocerca volvulus | 0.0031 | 0 | 0.5 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0031 | 0 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0031 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0031 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0098 | 0.2688 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0031 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.028 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0 | 0.5 |
Echinococcus multilocularis | cathepsin b | 0.028 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.028 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0031 | 0 | 0.5 |
Onchocerca volvulus | Cathepsin F homolog | 0.0031 | 0 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0098 | 0.2688 | 0.2688 |
Plasmodium vivax | vivapain-2 | 0.0031 | 0 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0031 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 1 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0098 | 0.2688 | 0.2688 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.028 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0031 | 0 | 0.5 |
Onchocerca volvulus | 0.0031 | 0 | 0.5 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0031 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.