Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.05 | 0.2876 | 0.5085 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0284 | 0.0707 | 0.5 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.0695 | 0.4825 | 0.4553 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.05 | 0.2876 | 0.5085 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0284 | 0.0707 | 0.1033 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0263 | 0.0499 | 0.0415 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.0695 | 0.4825 | 0.8016 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0527 | 0.3146 | 0.559 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0315 | 0.1016 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0284 | 0.0707 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0763 | 0.5505 | 1 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.0695 | 0.4825 | 0.4744 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0763 | 0.5505 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1211 | 1 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0284 | 0.0707 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.05 | 0.2876 | 0.5085 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.05 | 0.2876 | 0.5085 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0763 | 0.5505 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0284 | 0.0707 | 0.1033 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0263 | 0.0499 | 0.0415 |
Loa Loa (eye worm) | hypothetical protein | 0.0361 | 0.1474 | 0.134 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0284 | 0.0707 | 0.0561 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1211 | 1 | 1 |
Echinococcus granulosus | beta galactosidase | 0.0361 | 0.1474 | 0.1026 |
Trichomonas vaginalis | beta-galactosidase, putative | 0.0316 | 0.1028 | 0.1632 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0763 | 0.5505 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0763 | 0.5505 | 1 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0695 | 0.4825 | 0.563 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0284 | 0.0707 | 0.0219 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.05 | 0.2876 | 0.5085 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0284 | 0.0707 | 0.0561 |
Schistosoma mansoni | beta-galactosidase | 0.0361 | 0.1474 | 0.159 |
Echinococcus multilocularis | beta galactosidase | 0.0361 | 0.1474 | 0.1026 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0263 | 0.0499 | 0.0415 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0284 | 0.0707 | 0.1033 |
Trypanosoma brucei | glucosidase, putative | 0.0284 | 0.0707 | 0.5 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0284 | 0.0707 | 0.1033 |
Onchocerca volvulus | 0.0743 | 0.5308 | 1 | |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.0695 | 0.4825 | 0.4553 |
Schistosoma mansoni | alpha-glucosidase | 0.1057 | 0.845 | 1 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0284 | 0.0707 | 0.0219 |
Trichomonas vaginalis | glycoside hydrolase, putative | 0.0505 | 0.2922 | 0.5172 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0527 | 0.3146 | 0.559 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0284 | 0.0707 | 0.1033 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0284 | 0.0707 | 0.5 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0284 | 0.0707 | 0.1033 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0316 | 0.1028 | 0.1632 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0695 | 0.4825 | 0.563 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0763 | 0.5505 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0284 | 0.0707 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.1211 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.05 | 0.2876 | 0.5085 |
Schistosoma mansoni | alpha-glucosidase | 0.1057 | 0.845 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0284 | 0.0707 | 0.1033 |
Brugia malayi | Ceramide glucosyltransferase | 0.0695 | 0.4825 | 0.4744 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0284 | 0.0707 | 0.1033 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.05 | 0.2876 | 0.5085 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0763 | 0.5505 | 0.5434 |
Loa Loa (eye worm) | hypothetical protein | 0.0543 | 0.3298 | 0.3192 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0284 | 0.0707 | 0.1033 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.1211 | 1 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0284 | 0.0707 | 1 |
Schistosoma mansoni | hypothetical protein | 0.03 | 0.0865 | 0.0856 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0763 | 0.5505 | 0.5434 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0263 | 0.0499 | 0.0415 |
Schistosoma mansoni | alpha glucosidase | 0.0284 | 0.0707 | 0.0666 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.