Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | beta hexosaminidase subunit beta | 0.0204 | 0.0759 | 0.0759 |
Schistosoma mansoni | aminopeptidase P homologue (M24 family) | 0.1138 | 1 | 1 |
Trichomonas vaginalis | beta-hexosaminidase B, putative | 0.0128 | 0 | 0.5 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0128 | 0 | 0.5 |
Echinococcus multilocularis | bifunctional protein NCOAT | 0.1138 | 1 | 1 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0128 | 0 | 0.5 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, alpha subunit | 0.0204 | 0.0759 | 0.5 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, putative | 0.0204 | 0.0759 | 0.5 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, putative | 0.0204 | 0.0759 | 0.5 |
Echinococcus granulosus | beta hexosaminidase subunit beta | 0.0204 | 0.0759 | 0.0759 |
Echinococcus granulosus | bifunctional protein NCOAT | 0.1138 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0483 | 0.3522 | 0.299 |
Loa Loa (eye worm) | hyaluronidase | 0.1138 | 1 | 1 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0128 | 0 | 0.5 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, beta subunit | 0.0204 | 0.0759 | 0.5 |
Schistosoma mansoni | Hyaluronidase | 0.1138 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.