Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0123 | 0.0611 | 0.9086 |
Loa Loa (eye worm) | hypothetical protein | 0.1305 | 0.7688 | 1 |
Plasmodium falciparum | phosphodiesterase gamma, putative | 0.0035 | 0.0084 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.0071 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0071 | 0.0092 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0116 | 0.0569 | 0.0958 |
Mycobacterium tuberculosis | Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) (PBP1): penicillin-insensitive transglycosylase | 0.0246 | 0.1348 | 0.2289 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0035 | 0.0084 | 0.0257 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0035 | 0.0084 | 0.0257 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0084 | 0.1136 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding lipoprotein | 0.0311 | 0.1736 | 0.2953 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0116 | 0.0569 | 0.0635 |
Brugia malayi | Animal haem peroxidase family protein | 0.0027 | 0.0042 | 0.0054 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0149 | 0.2218 |
Brugia malayi | Animal haem peroxidase family protein | 0.0027 | 0.0042 | 0.0054 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0304 | 0.1697 | 0.3575 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0035 | 0.0084 | 0.1247 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0108 | 0.0522 | 0.0679 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0133 | 0.0673 | 0.2058 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0071 | 0.0216 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0027 | 0.0042 | 0.0054 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0149 | 0.0456 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0116 | 0.0569 | 0.8451 |
Chlamydia trachomatis | transglycolase/transpeptidase | 0.077 | 0.4486 | 0.4473 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0035 | 0.0084 | 0.0447 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0304 | 0.1697 | 0.3575 |
Plasmodium vivax | phosphodiesterase gamma, putative | 0.0035 | 0.0084 | 1 |
Treponema pallidum | penicillin-binding protein (pbp-2) | 0.0788 | 0.4595 | 0.4583 |
Onchocerca volvulus | 0.0032 | 0.0071 | 0.05 | |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0116 | 0.0569 | 0.074 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0027 | 0.0042 | 0.0054 |
Onchocerca volvulus | 0.0027 | 0.0042 | 0.0294 | |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0149 | 0.0194 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0024 | 0.0023 | 0.2721 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0035 | 0.0084 | 0.1136 |
Brugia malayi | Animal haem peroxidase family protein | 0.0027 | 0.0042 | 0.0054 |
Trypanosoma brucei | cAMP-specific phosphodiesterase, putative | 0.0035 | 0.0084 | 0.1136 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0086 | 0.0395 | 0.1207 |
Plasmodium falciparum | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0035 | 0.0084 | 1 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative | 0.0035 | 0.0084 | 0.0109 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0148 | 0.0766 | 0.1273 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0304 | 0.1697 | 0.3575 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0064 | 0.0944 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0043 | 0.0133 | 0.0832 |
Plasmodium falciparum | cGMP-specific phosphodiesterase | 0.0035 | 0.0084 | 1 |
Trypanosoma brucei | 3', 5'-cyclic nucleotide phosphodiesterase, putative | 0.0035 | 0.0084 | 0.1136 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0043 | 0.0133 | 0.1873 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0116 | 0.0569 | 0.0635 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0149 | 0.0456 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Schistosoma mansoni | ets-related | 0.0238 | 0.1301 | 0.3979 |
Plasmodium falciparum | phosphodiesterase delta, putative | 0.0035 | 0.0084 | 1 |
Mycobacterium ulcerans | penicillin-binding protein PbpA | 0.0999 | 0.5859 | 0.6784 |
Treponema pallidum | penicillin-binding protein (pbp-3) | 0.1462 | 0.8626 | 0.8623 |
Trypanosoma brucei | cAMP phosphodiesterase A, putative | 0.0035 | 0.0084 | 0.1136 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0148 | 0.0766 | 0.0864 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0304 | 0.1697 | 0.3575 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0071 | 0.0092 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0035 | 0.0084 | 0.0257 |
Loa Loa (eye worm) | glutaminase | 0.0567 | 0.3271 | 0.4254 |
Loa Loa (eye worm) | hypothetical protein | 0.0359 | 0.2025 | 0.2634 |
Echinococcus granulosus | high affinity cAMP specific 3'5' cyclic | 0.0035 | 0.0084 | 0.1247 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0133 | 0.0673 | 1 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0123 | 0.0611 | 0.9086 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0395 | 0.0514 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0078 | 0.0346 | 0.5147 |
Echinococcus multilocularis | high affinity cAMP specific 3',5' cyclic | 0.0035 | 0.0084 | 0.1247 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0078 | 0.0346 | 0.0451 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0071 | 0.105 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0304 | 0.1697 | 0.3575 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.0071 | 0.7829 |
Giardia lamblia | Hypothetical protein | 0.0035 | 0.0084 | 0.0447 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0304 | 0.1697 | 0.3575 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0035 | 0.0084 | 0.0109 |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsI | 0.1691 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0027 | 0.0042 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0086 | 0.0395 | 0.0514 |
Echinococcus multilocularis | dna polymerase kappa | 0.0043 | 0.0133 | 0.1975 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0304 | 0.1697 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.0071 | 0.105 |
Onchocerca volvulus | Dual oxidase homolog | 0.0027 | 0.0042 | 0.0294 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0133 | 0.0673 | 0.0875 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0304 | 0.1697 | 0.1678 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0024 | 0.0023 | 0.0025 |
Schistosoma mansoni | cgmp-dependent 35-cyclic phosphodiesterase | 0.0035 | 0.0084 | 0.0257 |
Plasmodium vivax | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0035 | 0.0084 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0024 | 0.0023 | 0.0217 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.0133 | 0.1873 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0035 | 0.0084 | 0.1247 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0043 | 0.0133 | 0.0128 |
Brugia malayi | Animal haem peroxidase family protein | 0.0027 | 0.0042 | 0.0054 |
Brugia malayi | hypothetical protein | 0.0138 | 0.0701 | 0.0912 |
Onchocerca volvulus | Peroxidasin homolog | 0.0027 | 0.0042 | 0.0294 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0133 | 0.0673 | 0.0875 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0084 | 0.1136 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0043 | 0.0133 | 0.0109 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0035 | 0.0084 | 0.1247 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0035 | 0.0084 | 0.0109 |
Giardia lamblia | hypothetical protein | 0.0035 | 0.0084 | 0.0447 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0133 | 0.0673 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0027 | 0.0042 | 0.0054 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0043 | 0.0133 | 0.0832 |
Onchocerca volvulus | Peroxidase homolog | 0.0027 | 0.0042 | 0.0294 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Onchocerca volvulus | 0.0256 | 0.1412 | 1 | |
Mycobacterium ulcerans | penicillin-binding membrane protein PbpB | 0.1462 | 0.8626 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0149 | 0.0194 |
Plasmodium vivax | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0035 | 0.0084 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0225 | 0.1225 | 0.1594 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0035 | 0.0084 | 0.1247 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0078 | 0.0346 | 0.5147 |
Mycobacterium leprae | PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSEN | 0.0543 | 0.3125 | 0.5315 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0133 | 0.0673 | 1 |
Treponema pallidum | penicillin-binding protein (pbp-1) | 0.1691 | 1 | 1 |
Plasmodium falciparum | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0035 | 0.0084 | 1 |
Brugia malayi | polk-prov protein | 0.0032 | 0.0071 | 0.0092 |
Onchocerca volvulus | 0.0027 | 0.0042 | 0.0294 | |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0035 | 0.0084 | 0.1136 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Brugia malayi | Peroxidasin | 0.0027 | 0.0042 | 0.0054 |
Loa Loa (eye worm) | PDE1B protein | 0.0035 | 0.0084 | 0.0109 |
Brugia malayi | Ets-domain containing protein | 0.0078 | 0.0346 | 0.0451 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.0133 | 0.1873 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0084 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Leishmania major | cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 | 0.0035 | 0.0084 | 0.1136 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Brugia malayi | glutaminase DH11.1 | 0.0567 | 0.3271 | 0.4254 |
Schistosoma mansoni | calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase | 0.0035 | 0.0084 | 0.0257 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0071 | 0.842 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0304 | 0.1697 | 0.3575 |
Schistosoma mansoni | peroxidasin | 0.0027 | 0.0042 | 0.0127 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0035 | 0.0084 | 0.0257 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0788 | 0.4595 | 1 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0024 | 0.0023 | 0.2721 |
Mycobacterium ulcerans | bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 | 0.0543 | 0.3125 | 0.3606 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0149 | 0.2218 |
Onchocerca volvulus | 0.0027 | 0.0042 | 0.0294 | |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0071 | 0.0216 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0256 | 0.1412 | 0.2943 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0036 | 0.0092 | 0.1255 |
Schistosoma mansoni | camp/cgmp cyclic nucleotide phosphodiesterase | 0.0035 | 0.0084 | 0.0257 |
Mycobacterium ulcerans | bifunctional penicillin-binding protein 1A/1B PonA1 | 0.0788 | 0.4595 | 0.5315 |
Brugia malayi | Ets-domain containing protein | 0.0078 | 0.0346 | 0.0451 |
Trypanosoma brucei | unspecified product | 0.0036 | 0.0092 | 0.1255 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0043 | 0.0133 | 0.1873 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0225 | 0.1225 | 0.1594 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0035 | 0.0084 | 0.1247 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0086 | 0.0395 | 0.5867 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0304 | 0.1697 | 1 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0133 | 0.0673 | 1 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0148 | 0.0766 | 0.1295 |
Echinococcus granulosus | dual 3'5' cyclic AMP and GMP phosphodiesterase | 0.0035 | 0.0084 | 0.1247 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0077 | 0.0338 | 0.502 |
Echinococcus granulosus | cAMP and cAMP inhibited cGMP 3'5' cyclic | 0.0035 | 0.0084 | 0.1247 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0035 | 0.0084 | 0.1247 |
Mycobacterium ulcerans | penicillin-binding lipoprotein | 0.0311 | 0.1736 | 0.1991 |
Echinococcus multilocularis | peroxidasin | 0.0027 | 0.0042 | 0.0617 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0116 | 0.0569 | 0.1739 |
Mycobacterium ulcerans | glutaminase | 0.0567 | 0.3271 | 0.3775 |
Loa Loa (eye worm) | hypothetical protein | 0.127 | 0.7481 | 0.9731 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0084 | 0.1136 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0149 | 0.2218 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0043 | 0.0133 | 0.0832 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0304 | 0.1697 | 1 |
Leishmania major | cAMP-specific phosphodiesterase, putative | 0.0035 | 0.0084 | 0.1136 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.0133 | 0.1873 |
Plasmodium vivax | cyclic nucleotide phosphodiesterase, putative | 0.0035 | 0.0084 | 1 |
Loa Loa (eye worm) | glutaminase 2 | 0.0567 | 0.3271 | 0.4254 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.0071 | 0.105 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0035 | 0.0084 | 0.0257 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0071 | 0.0216 |
Schistosoma mansoni | camp-specific cyclic nucleotide phosphodiesterase | 0.0035 | 0.0084 | 0.0257 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0084 | 0.0109 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0149 | 0.2218 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0032 | 0.0071 | 0.0938 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0035 | 0.0084 | 0.1247 |
Mycobacterium leprae | POSSIBLE PENICILLIN-BINDING LIPOPROTEIN | 0.0311 | 0.1736 | 0.2935 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0304 | 0.1697 | 0.3575 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0278 | 0.0362 |
Schistosoma mansoni | lipoxygenase | 0.0086 | 0.0391 | 0.1194 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0032 | 0.0071 | 0.0938 |
Onchocerca volvulus | Peroxidasin homolog | 0.0027 | 0.0042 | 0.0294 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0027 | 0.0042 | 0.0054 |
Trichomonas vaginalis | glutaminase, putative | 0.0567 | 0.3271 | 0.7064 |
Echinococcus multilocularis | high affinity cgmp specific 3' 5' cyclic | 0.0035 | 0.0084 | 0.1247 |
Brugia malayi | Fli-1 protein | 0.0238 | 0.1301 | 0.1693 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0035 | 0.0084 | 0.0257 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0086 | 0.0395 | 0.5867 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.0133 | 0.1873 |
Mycobacterium tuberculosis | Probable penicillin-binding membrane protein PbpB | 0.0459 | 0.2627 | 0.4476 |
Mycobacterium leprae | Probable penicillin-binding membrane protein PbpB | 0.0459 | 0.2627 | 0.4462 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0149 | 0.0456 |
Schistosoma mansoni | glutaminase | 0.0567 | 0.3271 | 1 |
Onchocerca volvulus | 0.0086 | 0.0395 | 0.2797 | |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0027 | 0.0042 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0084 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0071 | 0.0092 |
Echinococcus granulosus | high affinity cgmp specific 3' 5' cyclic | 0.0035 | 0.0084 | 0.1247 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0043 | 0.0133 | 0.0109 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0133 | 0.0673 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.0133 | 0.1873 |
Schistosoma mansoni | peroxidasin | 0.0027 | 0.0042 | 0.0127 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0035 | 0.0084 | 0.1247 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Brugia malayi | Animal haem peroxidase family protein | 0.0027 | 0.0042 | 0.0054 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0043 | 0.0133 | 0.0832 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.1305 | 0.7688 | 1 |
Schistosoma mansoni | gabp alpha | 0.0078 | 0.0346 | 0.1059 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.0133 | 0.1873 |
Schistosoma mansoni | high-affinity cgmp-specific 35-cyclic phosphodiesterase | 0.0035 | 0.0084 | 0.0257 |
Trypanosoma brucei | 3', 5'-cyclic nucleotide phosphodiesterase, putative | 0.0035 | 0.0084 | 0.1136 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0027 | 0.0042 | 0.0054 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.0133 | 0.1873 |
Echinococcus multilocularis | dual 3',5' cyclic AMP and GMP phosphodiesterase | 0.0035 | 0.0084 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0042 | 0.0054 |
Mycobacterium tuberculosis | Probable penicillin-binding protein PbpA | 0.0999 | 0.5859 | 1 |
Loa Loa (eye worm) | calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase | 0.0035 | 0.0084 | 0.0109 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative | 0.0035 | 0.0084 | 0.0109 |
Plasmodium falciparum | cGMP-specific phosphodiesterase | 0.0035 | 0.0084 | 1 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0077 | 0.0338 | 0.502 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.0133 | 0.1873 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0116 | 0.0569 | 0.8432 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0024 | 0.0023 | 0.0217 |
Loa Loa (eye worm) | fli-1 protein | 0.0238 | 0.1301 | 0.1693 |
Echinococcus multilocularis | cAMP and cAMP inhibited cGMP 3',5' cyclic | 0.0035 | 0.0084 | 0.1247 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0116 | 0.0569 | 0.8451 |
Mycobacterium tuberculosis | Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insen | 0.0543 | 0.3125 | 0.5326 |
Echinococcus granulosus | peroxidasin | 0.0027 | 0.0042 | 0.0617 |
Echinococcus granulosus | dna polymerase kappa | 0.0043 | 0.0133 | 0.1975 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0035 | 0.0084 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0043 | 0.0133 | 0.1873 |
Mycobacterium leprae | Probable penicillin-binding protein PbpA | 0.0999 | 0.5859 | 1 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0035 | 0.0084 | 0.0109 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0027 | 0.0042 | 0.0054 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0133 | 0.0673 | 0.3884 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0043 | 0.0133 | 0.0128 |
Mycobacterium leprae | PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE | 0.0788 | 0.4595 | 0.7834 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0133 | 0.0673 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0123 | 0.0611 | 0.1869 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.