Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Echinococcus granulosus | dnaJ subfamily B | 0.0397 | 0.222 | 0.2204 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.0252 | 0.0224 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0138 | 0.0109 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0017 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.003 | 0.001 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.0147 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.067 | 0.0642 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0236 | 0.131 | 0.1293 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Schistosoma mansoni | Hyaluronidase | 0.1778 | 1 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.0147 | 0.0127 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0238 | 0.0209 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0017 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0397 | 0.222 | 0.2204 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0252 | 0.0249 |
Trichomonas vaginalis | helicase, putative | 0.0006 | 0.0017 | 1 |
Schistosoma mansoni | aminopeptidase P homologue (M24 family) | 0.1778 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0238 | 0.0219 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0238 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0755 | 0.4237 | 0.422 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.002 | 0.0017 |
Loa Loa (eye worm) | hyaluronidase | 0.1778 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0238 | 0.021 |
Brugia malayi | hypothetical protein | 0.0236 | 0.131 | 0.1285 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.0279 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0138 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0236 | 0.131 | 0.1284 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0397 | 0.222 | 0.2217 |
Brugia malayi | hypothetical protein | 0.0122 | 0.067 | 0.0643 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0017 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0017 | 1 |
Echinococcus granulosus | bifunctional protein NCOAT | 0.1778 | 1 | 1 |
Onchocerca volvulus | 0.0048 | 0.0252 | 0.2144 | |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0236 | 0.131 | 0.1293 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0138 | 0.0109 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0017 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.067 | 0.0642 |
Echinococcus multilocularis | bifunctional protein NCOAT | 0.1778 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0238 | 0.0235 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0238 | 0.0235 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.003 | 0.001 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0017 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0238 | 0.0235 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0059 | 0.0314 | 0.0311 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0122 | 0.067 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.0252 | 0.0249 |
Onchocerca volvulus | Huntingtin homolog | 0.0122 | 0.067 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0017 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0017 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0238 | 0.0219 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0147 | 0.0144 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0017 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0147 | 0.0144 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0238 | 0.0219 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.