Detailed information for compound 830046

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 407.345 | Formula: C20H27BrN2O2
  • H donors: 0 H acceptors: 1 LogP: 3.64 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC12CN3CC(C2=O)(CN(C1)C3c1cc(Br)ccc1OCC)C
  • InChi: 1S/C20H27BrN2O2/c1-4-8-20-12-22-10-19(3,18(20)24)11-23(13-20)17(22)15-9-14(21)6-7-16(15)25-5-2/h6-7,9,17H,4-5,8,10-13H2,1-3H3
  • InChiKey: ICBWIRQAQBSERU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) ceramide glucosyltransferase 0.0737 0.3089 0.3089
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0522 0.2147 0.5599
Onchocerca volvulus 0.0104 0.0314 0.0218
Trichomonas vaginalis alpha-glucosidase, putative 0.0553 0.2284 0.3799
Loa Loa (eye worm) hypothetical protein 0.0093 0.0268 0.0268
Trichomonas vaginalis mannosyl-oligosaccharide alpha-1,2-mannosidase, putative 0.0094 0.0272 0.0452
Schistosoma mansoni phosphorylase B kinase beta kpbb 0.0069 0.0164 0.0088
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.1403 0.6012 0.5981
Trichomonas vaginalis conserved hypothetical protein 0.016 0.0559 0.093
Brugia malayi Glycosyl hydrolases family 31 protein 0.0553 0.2284 0.2225
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0002 0.0003
Trichomonas vaginalis endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative 0.0094 0.0272 0.0452
Trichomonas vaginalis alpha-mannosidase, putative 0.014 0.0475 0.0789
Echinococcus granulosus endoplasmic reticulum mannosyl oligosaccharide 0.0094 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0057 0.0109 0.0109
Brugia malayi Glycosyl hydrolases family 31 protein 0.027 0.1044 0.0975
Trichomonas vaginalis glucosylceramidase, putative 0.0921 0.3896 0.6481
Trichomonas vaginalis glucosylceramidase, putative 0.1403 0.6012 1
Trichomonas vaginalis glucosylceramidase, putative 0.1403 0.6012 1
Echinococcus multilocularis dihydrofolate reductase 0.0882 0.3726 0.3635
Brugia malayi phosphorylase B kinase alpha regulatory chain 0.0069 0.0164 0.0089
Loa Loa (eye worm) hypothetical protein 0.0089 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.027 0.1044 0.1044
Trichomonas vaginalis glucosylceramidase, putative 0.097 0.4114 0.6842
Trichomonas vaginalis glucosylceramidase, putative 0.0921 0.3896 0.6481
Echinococcus granulosus phosphorylase b kinase regulatory 0.0069 0.0164 0.0164
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0002 0.0003
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0143 0.0143
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0002 0.0003
Loa Loa (eye worm) mannosidase 0.0094 0.0272 0.0272
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0467 0.1908 0.8273
Trypanosoma brucei lysosomal alpha-mannosidase precursor, putative 0.0125 0.0408 0.1782
Schistosoma mansoni mannosyl-oligosaccharide alpha-12-mannosidase 0.0094 0.0272 0.021
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0553 0.2284 0.3799
Schistosoma mansoni glucose transport protein 0.0105 0.0318 0.0263
Echinococcus granulosus mannosyl oligosaccharide 12 alpha mannosidase 0.0094 0.0272 0.0272
Loa Loa (eye worm) alpha-L-fucosidase 0.0415 0.1678 0.1678
Loa Loa (eye worm) hypothetical protein 0.0094 0.0272 0.0272
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0467 0.1908 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.027 0.1044 0.1736
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0182 0.0657 0.1093
Echinococcus granulosus beta galactosidase 0.0371 0.1484 0.1484
Echinococcus granulosus lysosomal alpha mannosidase 0.0125 0.0408 0.0408
Trichomonas vaginalis glucosylceramidase, putative 0.1403 0.6012 1
Trichomonas vaginalis endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative 0.0094 0.0272 0.0452
Trypanosoma cruzi lysosomal alpha-mannosidase precursor, putative 0.0125 0.0408 0.1782
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0002 0.0003
Brugia malayi manba-prov protein 0.0052 0.0086 0.0011
Trichomonas vaginalis alpha-glucosidase, putative 0.027 0.1044 0.1736
Trichomonas vaginalis endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative 0.0094 0.0272 0.0452
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0105 0.0318 0.0178
Echinococcus granulosus tar DNA binding protein 0.0065 0.0143 0.0143
Trichomonas vaginalis mannosyl-oligosaccharide alpha-1,2-mannosidase, putative 0.0094 0.0272 0.0452
Schistosoma mansoni mannosidase alpha class 2a 0.0089 0.0249 0.0185
Trichomonas vaginalis glucosylceramidase, putative 0.0921 0.3896 0.6481
Echinococcus multilocularis endoplasmic reticulum mannosyl oligosaccharide 0.0094 0.0272 0.013
Echinococcus multilocularis beta galactosidase 0.0371 0.1484 0.1361
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0105 0.0318 0.0318
Trichomonas vaginalis alpha-glucosidase, putative 0.0553 0.2284 0.3799
Echinococcus multilocularis lysosomal alpha glucosidase 0.2313 1 1
Trichomonas vaginalis alpha-glucosidase, putative 0.027 0.1044 0.1736
Schistosoma mansoni alpha-l-fucosidase 0.0415 0.1678 0.1806
Onchocerca volvulus 0.0089 0.0249 0.0124
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.027 0.1044 0.1736
Echinococcus granulosus lysosomal alpha glucosidase 0.2313 1 1
Onchocerca volvulus Ceramide glucosyltransferase homolog 0.0737 0.3089 0.4239
Mycobacterium ulcerans alpha-mannosidase 0.014 0.0475 0.0872
Schistosoma mansoni alpha-glucosidase 0.2061 0.8897 1
Leishmania major alpha glucosidase II subunit, putative 0.0553 0.2284 1
Echinococcus multilocularis phosphorylase b kinase regulatory 0.0069 0.0164 0.0021
Loa Loa (eye worm) beta-glucuronidase 0.0052 0.0086 0.0086
Trichomonas vaginalis mannosyl-oligosaccharide alpha-1,2-mannosidase, putative 0.0094 0.0272 0.0452
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0143 0.0064
Loa Loa (eye worm) glycosyl hydrolase family 38 protein 0.014 0.0475 0.0475
Brugia malayi RNA binding protein 0.0065 0.0143 0.0068
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0182 0.0657 0.1093
Brugia malayi Sugar transporter family protein 0.0105 0.0318 0.0244
Trichomonas vaginalis alpha-glucosidase, putative 0.0553 0.2284 0.3799
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0318 0.0529
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0105 0.0318 0.0178
Trichomonas vaginalis mannosyl-oligosaccharide alpha-1,2-mannosidase, putative 0.0094 0.0272 0.0452
Trichomonas vaginalis glycoside hydrolases, putative 0.0128 0.0422 0.0701
Trypanosoma cruzi hypothetical protein, conserved 0.0553 0.2284 1
Trichomonas vaginalis alpha-mannosidase 2c1, putative 0.014 0.0475 0.0789
Echinococcus multilocularis neutral alpha glucosidase AB 0.0553 0.2284 0.2172
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0143 0.0143
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0105 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0081 0.0215 0.0215
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0143 0.0064
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0113 0.0356 0.0236
Trichomonas vaginalis glycoside hydrolase, putative 0.0255 0.0977 0.1625
Trypanosoma brucei glucosidase, putative 0.0553 0.2284 1
Toxoplasma gondii facilitative glucose transporter GT1 0.0105 0.0318 0.0987
Trichomonas vaginalis beta-glucosidase, putative 0.0128 0.0422 0.0701
Brugia malayi Glycosyl hydrolases family 2, sugar binding domain containing protein 0.0056 0.0105 0.003
Trichomonas vaginalis beta-mannosidase, putative 0.0052 0.0086 0.0143
Onchocerca volvulus Glucosylceramidase homolog 0.0921 0.3896 0.5408
Echinococcus granulosus fucosidase alpha L 1 tissue 0.0415 0.1678 0.1678
Echinococcus granulosus neutral alpha glucosidase AB 0.0553 0.2284 0.2284
Echinococcus granulosus phosphorylase b kinase regulatory 0.0069 0.0164 0.0164
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0143 0.0068
Loa Loa (eye worm) hypothetical protein 0.0281 0.1089 0.1089
Brugia malayi hypothetical protein 0.0069 0.0164 0.0089
Echinococcus multilocularis General substrate transporter 0.009 0.0254 0.0112
Schistosoma mansoni ceramide glucosyltransferase 0.0737 0.3089 0.3408
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.027 0.1044 0.4565
Brugia malayi Ceramide glucosyltransferase 0.0737 0.3089 0.3037
Trichomonas vaginalis beta-galactosidase, putative 0.016 0.0559 0.093
Trichomonas vaginalis glucosylceramidase, putative 0.0921 0.3896 0.6481
Brugia malayi dihydrofolate reductase family protein 0.0882 0.3726 0.3678
Loa Loa (eye worm) RNA binding protein 0.0065 0.0143 0.0143
Schistosoma mansoni glucose transport protein 0.0105 0.0318 0.0263
Trichomonas vaginalis glucosylceramidase, putative 0.097 0.4114 0.6842
Echinococcus granulosus non lysosomal glucosylceramidase 0.0416 0.1682 0.1682
Echinococcus multilocularis phosphorylase b kinase regulatory 0.0069 0.0164 0.0021
Trichomonas vaginalis alpha-glucosidase, putative 0.0553 0.2284 0.3799
Schistosoma mansoni bile acid beta-glucosidase-related 0.0416 0.1682 0.1811
Echinococcus multilocularis lysosomal alpha glucosidase 0.2313 1 1
Echinococcus multilocularis mannosyl oligosaccharide 1,2 alpha mannosidase 0.0094 0.0272 0.013
Loa Loa (eye worm) glycosyl hydrolase family 2 0.0056 0.0105 0.0105
Loa Loa (eye worm) thymidylate synthase 0.0104 0.0314 0.0314
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0076 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0164 0.0273
Entamoeba histolytica alpha-1,2-mannosidase, putative 0.0847 0.3573 1
Mycobacterium ulcerans alpha-L-fucosidase 0.0415 0.1678 0.4249
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0105 0.0318 0.0178
Brugia malayi Dihydrofolate reductase 0.0882 0.3726 0.3678
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0143 0.0064
Giardia lamblia Ceramide glucosyltransferase 0.0334 0.1324 0.5
Loa Loa (eye worm) dihydrofolate reductase 0.0882 0.3726 0.3726
Schistosoma mansoni hypothetical protein 0.0105 0.0318 0.0263
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0164 0.0273
Leishmania major glycosyl hydrolase-like protein 0.027 0.1044 0.4565
Mycobacterium ulcerans thymidylate synthase 0.0104 0.0314 0.0422
Brugia malayi TAR-binding protein 0.0065 0.0143 0.0068
Schistosoma mansoni ceramide glucosyltransferase 0.0737 0.3089 0.3408
Echinococcus granulosus thymidylate synthase 0.0104 0.0314 0.0314
Schistosoma mansoni lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) 0.0125 0.0408 0.0366
Brugia malayi Alpha-L-fucosidase family protein 0.0415 0.1678 0.1614
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0105 0.0318 0.0178
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0553 0.2284 1
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0164 0.0273
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0882 0.3726 1
Trichomonas vaginalis glucosylceramidase, putative 0.0921 0.3896 0.6481
Brugia malayi Glycosyl hydrolases family 38 protein 0.0089 0.0249 0.0175
Trichomonas vaginalis alpha-mannosidase 2c1, putative 0.0083 0.0225 0.0375
Echinococcus granulosus General substrate transporter 0.009 0.0254 0.0254
Echinococcus multilocularis fucosidase, alpha L 1, tissue 0.0415 0.1678 0.1557
Trichomonas vaginalis sucrase-isomaltase, putative 0.0522 0.2147 0.3571
Schistosoma mansoni bile acid beta-glucosidase-related 0.0416 0.1682 0.1811
Brugia malayi phosphorylase B kinase beta regulatory chain 0.0069 0.0164 0.0089
Chlamydia trachomatis dihydrofolate reductase 0.0882 0.3726 0.5
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0049 0.0076 0.0325
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0104 0.0314 0.0259
Brugia malayi lysosomal alpha-mannosidase 0.0089 0.0249 0.0175
Echinococcus multilocularis thymidylate synthase 0.0104 0.0314 0.0174
Loa Loa (eye worm) hypothetical protein 0.0069 0.0164 0.0164
Trichomonas vaginalis endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative 0.0094 0.0272 0.0452
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.2313 1 1
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0104 0.0314 0.0654
Trichomonas vaginalis maltase-glucoamylase, putative 0.0553 0.2284 0.3799
Trichomonas vaginalis glucosylceramidase, putative 0.0921 0.3896 0.6481
Trichomonas vaginalis glucosylceramidase, putative 0.1403 0.6012 1
Echinococcus multilocularis transfer RNA-Trp 0.0094 0.0272 0.013
Trichomonas vaginalis alpha-glucosidase, putative 0.027 0.1044 0.1736
Loa Loa (eye worm) hypothetical protein 0.0094 0.0272 0.0272
Schistosoma mansoni lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) 0.0089 0.0249 0.0185
Trichomonas vaginalis alpha-glucosidase, putative 0.027 0.1044 0.1736
Brugia malayi Beta-glucuronidase precursor 0.0052 0.0086 0.0011
Schistosoma mansoni alpha glucosidase 0.0553 0.2284 0.2495
Schistosoma mansoni glucose transport protein 0.0105 0.0318 0.0263
Brugia malayi Glycosyl hydrolases family 38 protein 0.014 0.0475 0.0402
Echinococcus granulosus ceramide glucosyltransferase 0.0737 0.3089 0.3089
Trichomonas vaginalis mannosyl-oligosaccharide alpha-1,2-mannosidase, putative 0.0094 0.0272 0.0452
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.027 0.1044 0.1274
Trichomonas vaginalis alpha-glucosidase, putative 0.027 0.1044 0.1736
Echinococcus multilocularis dnaJ subfamily B 0.0418 0.1692 0.1571
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0143 0.0064
Onchocerca volvulus 0.1644 0.7066 1
Trichomonas vaginalis endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative 0.0094 0.0272 0.0452
Trichomonas vaginalis mannosyl-oligosaccharide alpha-1,2-mannosidase, putative 0.0094 0.0272 0.0452
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0553 0.2284 0.3799
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0882 0.3726 1
Brugia malayi Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform 1 0.0094 0.0272 0.0197
Loa Loa (eye worm) sugar transporter 0.0105 0.0318 0.0318
Schistosoma mansoni hypothetical protein 0.0151 0.0523 0.0496
Trichomonas vaginalis endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative 0.0094 0.0272 0.0452
Trichomonas vaginalis glucosylceramidase, putative 0.0921 0.3896 0.6481
Echinococcus granulosus bile acid beta glucosidase 0.0416 0.1682 0.1682
Trichomonas vaginalis endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative 0.0094 0.0272 0.0452
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.027 0.1044 0.2195
Brugia malayi thymidylate synthase 0.0104 0.0314 0.024
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0467 0.1908 0.835
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0132 0.0052
Echinococcus granulosus dihydrofolate reductase 0.0882 0.3726 0.3726
Brugia malayi hypothetical protein 0.0069 0.0164 0.0089
Schistosoma mansoni lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) 0.0057 0.0109 0.0025
Loa Loa (eye worm) hypothetical protein 0.0089 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0371 0.1484 0.1484
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0467 0.1908 1
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0002 0.0003
Trichomonas vaginalis alpha-mannosidase 2c1, putative 0.0078 0.0202 0.0336
Trichomonas vaginalis glucosylceramidase, putative 0.1403 0.6012 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.0164 0.0164
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0553 0.2284 0.6023
Plasmodium vivax hypothetical protein, conserved 0.0113 0.0356 0.0236
Echinococcus multilocularis ceramide glucosyltransferase 0.0737 0.3089 0.2989
Schistosoma mansoni phosphorylase B kinase alpha kpb1 0.0069 0.0164 0.0088
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0143 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.1403 0.6012 1
Trichomonas vaginalis maltase-glucoamylase, putative 0.027 0.1044 0.1736
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0002 0.0003
Echinococcus granulosus dnaJ subfamily B 0.0418 0.1692 0.1692
Echinococcus multilocularis non lysosomal glucosylceramidase 0.0416 0.1682 0.1561
Echinococcus multilocularis alpha mannosidase 2 0.0089 0.0249 0.0108
Trypanosoma cruzi hypothetical protein, conserved 0.0553 0.2284 1
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0553 0.2284 0.2284
Mycobacterium tuberculosis Possible conserved exported protein 0.0847 0.3573 0.9581
Echinococcus multilocularis bile acid beta glucosidase 0.0416 0.1682 0.1561
Schistosoma mansoni dihydrofolate reductase 0.0882 0.3726 0.4131
Loa Loa (eye worm) hypothetical protein 0.0069 0.0164 0.0164
Trypanosoma cruzi lysosomal alpha-mannosidase precursor, putative 0.0125 0.0408 0.1782
Schistosoma mansoni beta-galactosidase 0.0371 0.1484 0.1587
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0882 0.3726 1
Schistosoma mansoni hypothetical protein 0.0418 0.1692 0.1822
Trichomonas vaginalis alpha-glucosidase, putative 0.0553 0.2284 0.3799
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.027 0.1044 0.4565
Trypanosoma brucei glycosyl hydrolase-like protein 0.027 0.1044 0.4565
Trichomonas vaginalis conserved hypothetical protein 0.0094 0.0272 0.0452
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.1403 0.6012 0.6012
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0105 0.0318 0.0318
Mycobacterium tuberculosis Conserved protein 0.0069 0.0164 0.0242
Onchocerca volvulus 0.0089 0.0249 0.0124
Loa Loa (eye worm) hypothetical protein 0.0554 0.2289 0.2289
Trypanosoma brucei lysosomal alpha-mannosidase precursor, putative 0.0099 0.0291 0.1269
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0467 0.1908 0.835
Brugia malayi Glycosyl hydrolases family 38 protein 0.0089 0.0249 0.0175
Loa Loa (eye worm) myosin heavy chain 0.0069 0.0164 0.0164
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0105 0.0318 0.0318
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0467 0.1908 0.835
Schistosoma mansoni alpha-glucosidase 0.2061 0.8897 1
Echinococcus multilocularis lysosomal alpha mannosidase 0.0125 0.0408 0.0269
Loa Loa (eye worm) hypothetical protein 0.0069 0.0164 0.0164

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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