TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 394.49 | Formula: C21H22N4O2S
H donors: 1 H acceptors: 2 LogP: 3.62 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: CCC(n1nc(C)n2c(c1=O)cc1c2ccs1)C(=O)NCc1ccc(cc1)C
InChi: 1S/C21H22N4O2S/c1-4-16(20(26)22-12-15-7-5-13(2)6-8-15)25-21(27)18-11-19-17(9-10-28-19)24(18)14(3)23-25/h5-11,16H,4,12H2,1-3H3,(H,22,26)
InChiKey: BUFCMKDVBYTHPV-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Entamoeba histolytica	cysteine proteinase, putative	0.0464	0.2008	0.9207
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.058	0.2569	0.7261
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0489	0.2129	0.5237
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0172	0.0608	0.0608
Loa Loa (eye worm)	hypothetical protein	0.0172	0.0608	0.0608
Brugia malayi	Papain family cysteine protease containing protein	0.0197	0.0728	0.0728
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0489	0.2129	0.5237
Echinococcus multilocularis	tar DNA binding protein	0.0063	0.0084	0.0018
Entamoeba histolytica	cysteine protease, putative	0.0197	0.0728	0.0793
Schistosoma mansoni	hypothetical protein	0.0304	0.1242	0.1183
Brugia malayi	Cathepsin L-like precursor	0.0489	0.2129	0.2129
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.058	0.2569	0.7261
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0304	0.1242	0.1242
Brugia malayi	TAR-binding protein	0.0063	0.0084	0.0084
Brugia malayi	cahepsin L-like non-peptiedase homolog	0.0172	0.0608	0.0608
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.058	0.2569	0.7261
Echinococcus multilocularis	cathepsin b	0.2129	1	1
Onchocerca volvulus		0.0489	0.2129	1
Onchocerca volvulus	Dipeptidyl peptidase family member 1 homolog	0.0175	0.0624	0.0109
Entamoeba histolytica	cysteine protease, putative	0.0197	0.0728	0.0793
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0464	0.2008	0.4822
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0489	0.2129	0.2076
Echinococcus granulosus	cathepsin b	0.2129	1	1
Loa Loa (eye worm)	hypothetical protein	0.0172	0.0608	0.0608
Trypanosoma cruzi	cysteine peptidase, putative	0.058	0.2569	0.2519
Echinococcus granulosus	dipeptidyl aminopeptidaseprotein	0.0175	0.0624	0.0561
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0197	0.0728	0.192
Trypanosoma cruzi	cysteine proteinase, putative	0.0197	0.0728	0.0666
Loa Loa (eye worm)	hypothetical protein	0.0464	0.2008	0.2008
Schistosoma mansoni	cathepsin S (C01 family)	0.0172	0.0608	0.0545
Entamoeba histolytica	cysteine proteinase, putative	0.0197	0.0728	0.0793
Brugia malayi	cathepsin L-like precursor	0.0464	0.2008	0.2008
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0777	0.3513	1
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0489	0.2129	1
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0555	0.2448	0.2397
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.0777	0.3513	1
Toxoplasma gondii	preprocathepsin c precursor, putative	0.0172	0.0608	0.157
Brugia malayi	Papain family cysteine protease containing protein	0.0172	0.0608	0.0608
Brugia malayi	cathepsin F-like cysteine proteinase	0.0172	0.0608	0.0608
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0489	0.2129	0.5237
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0172	0.0608	0.0545
Brugia malayi	Cathepsin L-like precursor	0.0489	0.2129	0.2129
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0489	0.2129	0.5237
Brugia malayi	Cathepsin L-like precursor	0.0489	0.2129	0.2129
Toxoplasma gondii	cathepsin CPC2	0.0172	0.0608	0.157
Entamoeba histolytica	cysteine protease, putative	0.0197	0.0728	0.0793
Loa Loa (eye worm)	TAR-binding protein	0.0063	0.0084	0.0084
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0489	0.2129	0.5237
Brugia malayi	fibroinase precursor	0.0172	0.0608	0.0608
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.058	0.2569	0.7261
Brugia malayi	RNA, U transporter 1	0.0081	0.0172	0.0172
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0172	0.0608	0.0545
Loa Loa (eye worm)	hypothetical protein	0.0172	0.0608	0.0608
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0172	0.0608	0.0545
Schistosoma mansoni	cathepsin B (C01 family)	0.0172	0.0608	0.0545
Toxoplasma gondii	cathepsin B	0.0777	0.3513	1
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.0172	0.0608	0.0545
Entamoeba histolytica	cysteine protease, putative	0.0197	0.0728	0.0793
Trypanosoma cruzi	cysteine peptidase, putative	0.058	0.2569	0.2519
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.058	0.2569	0.7261
Echinococcus multilocularis	cathepsin L	0.0197	0.0728	0.0666
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.0084	0.0018
Loa Loa (eye worm)	cathepsin B	0.0777	0.3513	0.3513
Giardia lamblia	Cathepsin B precursor	0.0777	0.3513	1
Brugia malayi	prolyl oligopeptidase family protein	0.0175	0.0624	0.0624
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0489	0.2129	0.5237
Entamoeba histolytica	cysteine protease, putative	0.0197	0.0728	0.0793
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0172	0.0608	0.0608
Onchocerca volvulus		0.0489	0.2129	1
Schistosoma mansoni	cathepsin F (C01 family)	0.0489	0.2129	0.2076
Brugia malayi	cathepsin L precursor	0.0172	0.0608	0.0608
Plasmodium vivax	vivapain-2	0.0489	0.2129	1
Brugia malayi	Cathepsin L-like precursor	0.0489	0.2129	0.2129
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.2129	1	1
Trypanosoma cruzi	cysteine proteinase, putative	0.0197	0.0728	0.0666
Toxoplasma gondii	cathepsin CPL	0.0489	0.2129	0.5985
Leishmania major	cathepsin L-like protease	0.058	0.2569	0.7261
Echinococcus multilocularis	cathepsin L cysteine protease	0.0489	0.2129	0.2076
Trypanosoma cruzi	cysteine peptidase, putative	0.058	0.2569	0.2519
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0489	0.2129	0.5237
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0197	0.0728	0.0415
Entamoeba histolytica	cysteine proteinase 2	0.0197	0.0728	0.0793
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0489	0.2129	0.2076
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0489	0.2129	0.5237
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0197	0.0728	0.0666
Entamoeba histolytica	cysteine proteinase, putative	0.0197	0.0728	0.0793
Echinococcus multilocularis	cathepsin L	0.0172	0.0608	0.0545
Entamoeba histolytica	cysteine proteinase 1, putative	0.0197	0.0728	0.0793
Echinococcus granulosus	snurportin 1	0.0304	0.1242	0.1183
Trypanosoma cruzi	major cysteine proteinase, putative	0.0172	0.0608	0.0545
Echinococcus granulosus	cathepsin L	0.0197	0.0728	0.0666
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0489	0.2129	0.2076
Leishmania major	cathepsin L-like protease	0.058	0.2569	0.7261
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0489	0.2129	0.5237
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0489	0.2129	0.5237
Giardia lamblia	Cathepsin B precursor	0.0777	0.3513	1
Echinococcus multilocularis	cathepsin L cysteine protease	0.0489	0.2129	0.2076
Loa Loa (eye worm)	cysteine protease	0.0489	0.2129	0.2129
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0172	0.0608	0.0545
Loa Loa (eye worm)	hypothetical protein	0.0464	0.2008	0.2008
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0489	0.2129	1
Loa Loa (eye worm)	RNA binding protein	0.0063	0.0084	0.0084
Entamoeba histolytica	cysteine proteinase, putative	0.0489	0.2129	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.2129	1	1
Toxoplasma gondii	cathepsin CPC1	0.0172	0.0608	0.157
Echinococcus multilocularis	cysteine protease	0.0489	0.2129	0.2076
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.058	0.2569	0.7261
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0197	0.0728	0.0793
Echinococcus granulosus	cathepsin b	0.2129	1	1
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0172	0.0608	0.0545
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0489	0.2129	0.5237
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0197	0.0728	0.0666
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.0084	0.0018
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0197	0.0728	0.0666
Loa Loa (eye worm)	hypothetical protein	0.0489	0.2129	0.2129
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.2129	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0489	0.2129	0.5237
Brugia malayi	Papain family cysteine protease containing protein	0.0172	0.0608	0.0608
Entamoeba histolytica	cysteine protease, putative	0.0197	0.0728	0.0793
Schistosoma mansoni	cathepsin C	0.0172	0.0608	0.0545
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0777	0.3513	0.3469
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0489	0.2129	0.2076
Echinococcus granulosus	cathepsin L	0.0172	0.0608	0.0545
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0464	0.2008	0.4822
Echinococcus granulosus	tar DNA binding protein	0.0063	0.0084	0.0018
Trypanosoma cruzi	major cysteine proteinase, putative	0.0263	0.1047	0.0987
Loa Loa (eye worm)	hypothetical protein	0.2129	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0197	0.0728	0.192
Onchocerca volvulus	Cathepsin L homolog	0.0489	0.2129	1
Brugia malayi	prolyl oligopeptidase family protein	0.0059	0.0067	0.0067
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0489	0.2129	0.5237
Echinococcus granulosus	cysteine protease	0.0197	0.0728	0.0666
Brugia malayi	RNA binding protein	0.0063	0.0084	0.0084
Loa Loa (eye worm)	hypothetical protein	0.0464	0.2008	0.2008
Plasmodium vivax	vivapain-2	0.0489	0.2129	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.058	0.2569	0.7261
Onchocerca volvulus		0.0489	0.2129	1
Giardia lamblia	Cathepsin B precursor	0.0777	0.3513	1
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0489	0.2129	1
Echinococcus granulosus	cathepsin L cysteine protease	0.0197	0.0728	0.0666
Brugia malayi	Papain family cysteine protease containing protein	0.0197	0.0728	0.0728
Trypanosoma cruzi	cysteine peptidase, putative	0.0489	0.2129	0.2076
Entamoeba histolytica	cysteine protease, putative	0.0197	0.0728	0.0793
Trypanosoma cruzi	cruzipain precursor, putative	0.058	0.2569	0.2519
Leishmania major	cathepsin L-like protease	0.058	0.2569	0.7261
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0489	0.2129	0.5237
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0489	0.2129	0.5237
Entamoeba histolytica	cysteine protease, putative	0.0197	0.0728	0.0793
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0489	0.2129	0.5237
Entamoeba histolytica	cysteine protease, putative	0.0197	0.0728	0.0793
Loa Loa (eye worm)	hypothetical protein	0.0172	0.0608	0.0608
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.058	0.2569	0.7261
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0489	0.2129	0.5237
Onchocerca volvulus		0.0489	0.2129	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0489	0.2129	0.5237
Onchocerca volvulus		0.0489	0.2129	1
Echinococcus multilocularis	cathepsin b	0.2129	1	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.2129	1	1
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.0084	0.0018
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0172	0.0608	0.0608
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.0084	0.0018
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0063	0.0084	0.0084
Schistosoma mansoni	cathepsin F (C01 family)	0.0464	0.2008	0.1955
Brugia malayi	Papain family cysteine protease containing protein	0.0172	0.0608	0.0608
Brugia malayi	RNA recognition motif domain containing protein	0.0063	0.0084	0.0084
Entamoeba histolytica	cysteine proteinase, putative	0.0197	0.0728	0.0793
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0777	0.3513	1
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.0172	0.0608	0.0608
Schistosoma mansoni	cathepsin F (C01 family)	0.0489	0.2129	0.2076
Loa Loa (eye worm)	ctsf protein	0.0489	0.2129	0.2129
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0489	0.2129	0.5237
Plasmodium vivax	vivapain-1	0.0197	0.0728	0.0793
Loa Loa (eye worm)	hypothetical protein	0.0172	0.0608	0.0608
Leishmania major	cathepsin L-like protease	0.0489	0.2129	0.5985
Schistosoma mansoni	tar DNA-binding protein	0.0063	0.0084	0.0018
Brugia malayi	Cathepsin L-like precursor	0.0464	0.2008	0.2008
Echinococcus multilocularis	dipeptidyl aminopeptidaseprotein	0.0175	0.0624	0.0561
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0172	0.0608	0.0608
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0489	0.2129	0.2129
Brugia malayi	Cathepsin L-like precursor	0.0489	0.2129	0.2129
Loa Loa (eye worm)	fibroinase	0.0489	0.2129	0.2129
Echinococcus granulosus	cathepsin l1	0.0464	0.2008	0.1955
Entamoeba histolytica	cysteine protease, putative	0.0489	0.2129	1
Leishmania major	cathepsin L-like protease	0.0489	0.2129	0.5985
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0197	0.0728	0.0415
Echinococcus multilocularis	snurportin 1	0.0304	0.1242	0.1183
Entamoeba histolytica	cysteine proteinase, putative	0.0489	0.2129	1
Entamoeba histolytica	cysteine protease, putative	0.0197	0.0728	0.0793
Leishmania major	cathepsin L-like protease	0.0489	0.2129	0.5985
Onchocerca volvulus	Cathepsin L homolog	0.0489	0.2129	1
Entamoeba histolytica	cysteine protease, putative	0.0197	0.0728	0.0793
Loa Loa (eye worm)	hypothetical protein	0.0172	0.0608	0.0608
Entamoeba histolytica	cysteine proteinase, putative	0.0197	0.0728	0.0793
Onchocerca volvulus		0.0464	0.2008	0.9207
Brugia malayi	Cathepsin L-like precursor	0.0464	0.2008	0.2008
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0777	0.3513	0.3469
Entamoeba histolytica	cysteine protease, putative	0.0197	0.0728	0.0793
Brugia malayi	cathepsin L-like cysteine proteinase	0.0172	0.0608	0.0608
Leishmania major	cysteine peptidase A (CPA)	0.0489	0.2129	0.5985
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0489	0.2129	0.5237
Onchocerca volvulus		0.0489	0.2129	1
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0489	0.2129	0.2129
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0489	0.2129	0.5237
Onchocerca volvulus	Cathepsin F homolog	0.0489	0.2129	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0197	0.0728	0.0666
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.058	0.2569	0.7261
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0489	0.2129	0.5237
Plasmodium vivax	unspecified product	0.0197	0.0728	0.0793
Leishmania major	cathepsin L-like protease	0.0489	0.2129	0.5985
Echinococcus granulosus	cathepsin l1	0.0489	0.2129	0.2076
Leishmania major	cathepsin L-like protease	0.0489	0.2129	0.5985
Brugia malayi	Cathepsin L-like precursor	0.0489	0.2129	0.2129
Echinococcus multilocularis	cysteine protease	0.0489	0.2129	0.2076
Loa Loa (eye worm)	prolyl oligopeptidase	0.0175	0.0624	0.0624
Schistosoma mansoni	subfamily S9B unassigned peptidase (S09 family)	0.0175	0.0624	0.0561
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0172	0.0608	0.0545
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.058	0.2569	0.7261
Brugia malayi	Papain family cysteine protease containing protein	0.0489	0.2129	0.2129
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0489	0.2129	0.5237
Trypanosoma cruzi	cysteine protease, putative	0.0197	0.0728	0.0666
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0489	0.2129	0.5237
Entamoeba histolytica	cysteine protease, putative	0.0197	0.0728	0.0793
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0172	0.0608	0.0545
Onchocerca volvulus		0.0489	0.2129	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.058	0.2569	0.7261
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0197	0.0728	0.0666
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.2129	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0489	0.2129	0.5237
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0464	0.2008	0.2008
Plasmodium vivax	vivapain-3	0.0197	0.0728	0.0793
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.0172	0.0608	0.0545

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 832465