Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Schistosoma mansoni | aldo-keto reductase | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Trypanosoma cruzi | aldo-keto reductase | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 0 | 0.5 |
Toxoplasma gondii | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0 | 0.5 |
Mycobacterium tuberculosis | Isocitrate lyase Icl (isocitrase) (isocitratase) | 0.0554 | 1 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Leishmania major | prostaglandin f synthase, putative | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) | 0.0554 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Schistosoma mansoni | pol-related | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0033 | 0 | 0.5 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 0 | 0.5 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Mycobacterium ulcerans | isocitrate lyase AceAb | 0.0554 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 0 | 0.5 |
Trypanosoma brucei | prostaglandin f synthase | 0.0033 | 0 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0033 | 0 | 0.5 |
Mycobacterium ulcerans | isocitrate lyase Icl | 0.0554 | 1 | 1 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Schistosoma mansoni | aldo-keto reductase | 0.0033 | 0 | 0.5 |
Mycobacterium leprae | Isocitrate lyase | 0.026 | 0.4348 | 0.4348 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Onchocerca volvulus | 0.0033 | 0 | 0.5 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0033 | 0 | 0.5 |
Leishmania major | aldo-keto reductase-like protein | 0.0033 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) | 0.0554 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 0 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0033 | 0 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0033 | 0 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0033 | 0 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0033 | 0 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0033 | 0 | 0.5 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0033 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.