Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0574 | 0.3673 | 0.3673 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.1328 | 1 | 1 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.1328 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0545 | 0.3424 | 0.3424 |
Echinococcus multilocularis | hormone sensitive lipase | 0.1328 | 1 | 1 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0136 | 0 | 0.5 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0574 | 0.3673 | 0.5 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0136 | 0 | 0.5 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.1328 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1328 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.