Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | P-glycoprotein-2 | 0.0034 | 0.0146 | 0.5 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0034 | 0.0146 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0146 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.2796 | 0.2784 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0034 | 0.0146 | 1 |
Toxoplasma gondii | ATP-binding cassette transporter ABC.B1 | 0.0034 | 0.0146 | 0.5 |
Trichomonas vaginalis | taga, putative | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0034 | 0.0146 | 1 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0723 | 0.9688 | 0.9688 |
Entamoeba histolytica | P-glycoprotein-2, putative | 0.0034 | 0.0146 | 0.5 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0034 | 0.0146 | 1 |
Loa Loa (eye worm) | multidrug resistance protein 3 | 0.0034 | 0.0146 | 0.0005 |
Leishmania major | fatty-acid desaturase, putative | 0.0745 | 1 | 1 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0034 | 0.0146 | 1 |
Onchocerca volvulus | 0.0745 | 0.999 | 1 | |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0034 | 0.0146 | 1 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0723 | 0.9688 | 0.9688 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | abcb9, putative | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | ABC transporter, putative | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | ABC transporter, putative | 0.0034 | 0.0146 | 1 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | ABC transporter, half transporter, putative | 0.0034 | 0.0146 | 1 |
Echinococcus multilocularis | ATP binding cassette sub family B | 0.0033 | 0.0141 | 0.9639 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0034 | 0.0146 | 1 |
Brugia malayi | Delta5 fatty acid desaturase | 0.0225 | 0.2796 | 0.278 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0745 | 1 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0034 | 0.0146 | 1 |
Schistosoma mansoni | fatty acid desaturase | 0.0226 | 0.2806 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0 | 0.5 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | abcb9, putative | 0.0034 | 0.0146 | 1 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0034 | 0.0146 | 1 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.0034 | 0.0146 | 1 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | abcb9, putative | 0.0034 | 0.0146 | 1 |
Entamoeba histolytica | P-glycoprotein 5, putative | 0.0034 | 0.0146 | 0.5 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | ABC transporter, putative | 0.0034 | 0.0146 | 1 |
Mycobacterium tuberculosis | Probable transmembrane multidrug efflux pump | 0.0034 | 0.0146 | 1 |
Loa Loa (eye worm) | FAT-3 protein | 0.0225 | 0.2796 | 0.2784 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0034 | 0.0146 | 1 |
Leishmania major | p-glycoprotein | 0.0034 | 0.0146 | 0.0146 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0034 | 0.0146 | 1 |
Entamoeba histolytica | P-glycoprotein-1 | 0.0034 | 0.0146 | 0.5 |
Entamoeba histolytica | P-glyco protein 6, putative | 0.0034 | 0.0146 | 0.5 |
Onchocerca volvulus | 0.0226 | 0.2806 | 0.2702 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0146 | 0.0005 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.0034 | 0.0146 | 1 |
Entamoeba histolytica | P-glycoprotein-2 | 0.0034 | 0.0146 | 0.5 |
Plasmodium falciparum | stearoyl-CoA desaturase | 0.0722 | 0.9678 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0034 | 0.0146 | 1 |
Plasmodium vivax | stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative | 0.0722 | 0.9678 | 1 |
Trichomonas vaginalis | ABC transporter, half transporter, putative | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0034 | 0.0146 | 1 |
Chlamydia trachomatis | ABC transporter ATP binding protein/permease | 0.0034 | 0.0146 | 0.5 |
Onchocerca volvulus | 0.0745 | 0.999 | 1 | |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0034 | 0.0146 | 1 |
Toxoplasma gondii | ABC transporter transmembrane region domain-containing protein | 0.0034 | 0.0146 | 0.5 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | ABC transporter, putative | 0.0034 | 0.0146 | 1 |
Loa Loa (eye worm) | ATP-binding cassette sub-family B member 2 | 0.0034 | 0.0146 | 0.0005 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0034 | 0.0146 | 1 |
Trypanosoma brucei | fatty acid desaturase, putative | 0.0745 | 1 | 0.5 |
Loa Loa (eye worm) | acyl-CoA desaturase | 0.0722 | 0.9678 | 1 |
Brugia malayi | acyl-CoA desaturase | 0.0722 | 0.9678 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0203 | 0.2484 | 0.2457 |
Entamoeba histolytica | P-glycoprotein-5 | 0.0034 | 0.0146 | 0.5 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0034 | 0.0146 | 1 |
Leishmania major | delta-5 fatty acid desaturase | 0.0225 | 0.2796 | 0.2796 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0034 | 0.0146 | 1 |
Echinococcus granulosus | 5'partial|ATP binding cassette sub family B | 0.0033 | 0.0141 | 0.9639 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0034 | 0.0146 | 1 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0034 | 0.0146 | 1 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0034 | 0.0146 | 1 |
Leishmania major | ATP-binding cassette protein subfamily B, member 2, putative | 0.0034 | 0.0146 | 0.0146 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.