Detailed information for compound 864661

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 415.552 | Formula: C21H29N5O2S
  • H donors: 1 H acceptors: 4 LogP: 3.68 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCn1c2nnc(n2c2c(c1=O)scc2)CCCC(=O)NC1CCCCCC1
  • InChi: 1S/C21H29N5O2S/c1-2-13-25-20(28)19-16(12-14-29-19)26-17(23-24-21(25)26)10-7-11-18(27)22-15-8-5-3-4-6-9-15/h12,14-15H,2-11,13H2,1H3,(H,22,27)
  • InChiKey: LNYUWITYLADGGX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Echinococcus multilocularis musashi 0.0029 0.0029 0.0029
Schistosoma mansoni opsin-like receptor 0.0057 0.0072 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0072 0.0072
Echinococcus multilocularis cysteine protease 0.2534 0.3851 0.3851
Echinococcus granulosus tm gpcr rhodopsin 0.0057 0.0072 0.0072
Schistosoma mansoni cathepsin s 0.0715 0.1077 0.1077
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2534 0.3851 0.5661
Plasmodium falciparum serine repeat antigen 4 0.0769 0.1159 0.3009
Onchocerca volvulus 0.0057 0.0072 0.0113
Entamoeba histolytica cysteine proteinase 1, putative 0.1485 0.225 0.5843
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0057 0.0072 0.0072
Brugia malayi Serotonin receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Trichomonas vaginalis CAMK family protein kinase 0.0074 0.0098 0.0144
Brugia malayi Cathepsin L-like precursor 0.1819 0.276 0.276
Entamoeba histolytica cysteine protease, putative 0.0769 0.1159 0.3009
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Schistosoma mansoni neuropeptide f receptor 76f 0.0057 0.0072 0.0072
Trypanosoma cruzi cysteine peptidase, putative 0.1485 0.225 0.225
Onchocerca volvulus 0.0057 0.0072 0.0113
Echinococcus multilocularis neuropeptides capa receptor 0.0057 0.0072 0.0072
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.6564 1 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0769 0.1159 0.1703
Toxoplasma gondii 6-phosphofructokinase 0.0023 0.002 0.003
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0769 0.1159 0.1159
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0023 0.002 0.0053
Trypanosoma cruzi cysteine proteinase, putative 0.1485 0.225 0.225
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0221 0.0323 0.0323
Giardia lamblia Cathepsin L-like protease 0.0769 0.1159 0.1703
Giardia lamblia Cathepsin L precursor 0.0769 0.1159 0.1703
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0769 0.1159 0.1703
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0029 0.0029
Echinococcus granulosus g-protein coupled receptor 0.0057 0.0072 0.0072
Plasmodium vivax SET domain protein, putative 0.0032 0.0034 0.0087
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2534 0.3851 0.5661
Echinococcus multilocularis allatostatin A receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Brugia malayi Dopamine receptor protein 1 0.0057 0.0072 0.0072
Trypanosoma cruzi cysteine proteinase, putative 0.1485 0.225 0.225
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2534 0.3851 0.5661
Schistosoma mansoni hypothetical protein 0.0057 0.0072 0.0072
Schistosoma mansoni cathepsin F (C01 family) 0.2534 0.3851 0.3851
Plasmodium vivax vivapain-1 0.1485 0.225 0.5843
Trichomonas vaginalis CAMK family protein kinase 0.0074 0.0098 0.0144
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0769 0.1159 0.3009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Brugia malayi RE15519p 0.0057 0.0072 0.0072
Onchocerca volvulus 0.2534 0.3851 1
Brugia malayi sulfakinin receptor protein 0.0057 0.0072 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0072 0.0072
Echinococcus granulosus 6 phosphofructokinase 0.0085 0.0115 0.0115
Echinococcus granulosus peptide allatostatin:somatostatin 0.0057 0.0072 0.0072
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.2534 0.3851 0.3851
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0769 0.1159 0.3009
Trypanosoma brucei polo-like protein kinase 0.0074 0.0098 0.0126
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0009 0.0009
Echinococcus granulosus neuropeptide FF receptor 2 0.0057 0.0072 0.0072
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0057 0.0072 0.0072
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0769 0.1159 0.1159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2534 0.3851 0.5661
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2534 0.3851 0.5661
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0769 0.1159 0.1703
Loa Loa (eye worm) hypothetical protein 0.1819 0.276 0.276
Trichomonas vaginalis CAMK family protein kinase 0.0037 0.0041 0.006
Echinococcus granulosus allatostatin A receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Entamoeba histolytica cysteine proteinase, putative 0.2534 0.3851 1
Entamoeba histolytica cysteine protease, putative 0.1485 0.225 0.5843
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Plasmodium vivax vivapain-2 0.2534 0.3851 1
Toxoplasma gondii cathepsin B 0.4469 0.6803 1
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0769 0.1159 0.3009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2534 0.3851 0.5661
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2534 0.3851 0.5661
Schistosoma mansoni lamin 0.0029 0.0029 0.0029
Echinococcus granulosus g protein coupled receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0057 0.0072 0.0072
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0023 0.002 0.003
Plasmodium falciparum serine repeat antigen 3 0.0769 0.1159 0.3009
Schistosoma mansoni amine GPCR 0.0057 0.0072 0.0072
Echinococcus granulosus neuropeptides capa receptor 0.0057 0.0072 0.0072
Leishmania major cathepsin L-like protease 0.2534 0.3851 0.4959
Onchocerca volvulus Cathepsin L homolog 0.2534 0.3851 1
Trypanosoma cruzi cysteine peptidase, putative 0.2534 0.3851 0.3851
Trichomonas vaginalis phosphofructokinase, putative 0.0085 0.0115 0.0169
Plasmodium falciparum serine repeat antigen 2 0.0769 0.1159 0.3009
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0023 0.002 0.003
Brugia malayi hypothetical protein 0.0057 0.0072 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.51 0.7766 1
Echinococcus granulosus orexin receptor type 2 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.4469 0.6803 0.6803
Echinococcus granulosus cathepsin l1 0.1819 0.276 0.276
Echinococcus granulosus cathepsin L cysteine proteinase 0.2534 0.3851 0.3851
Plasmodium vivax unspecified product 0.1485 0.225 0.5843
Brugia malayi Cathepsin L-like precursor 0.0715 0.1077 0.1077
Loa Loa (eye worm) 6-phosphofructokinase 0.0085 0.0115 0.0115
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0057 0.0072 0.0072
Echinococcus multilocularis somatostatin receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0769 0.1159 0.1159
Onchocerca volvulus 0.2534 0.3851 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Brugia malayi hypothetical protein 0.0057 0.0072 0.0072
Echinococcus multilocularis G protein coupled receptor 139 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0769 0.1159 0.1703
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0769 0.1159 0.3009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2534 0.3851 0.5661
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0029
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0057 0.0072 0.0072
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0057 0.0072 0.0072
Onchocerca volvulus 0.1819 0.276 0.7144
Echinococcus granulosus hypothetical protein 0.0057 0.0072 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.51 0.7766 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.4384 0.6675 0.6675
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0057 0.0072 0.0072
Brugia malayi Papain family cysteine protease containing protein 0.1485 0.225 0.225
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0072 0.0072
Echinococcus granulosus cathepsin l cysteine peptidase 0.2534 0.3851 0.3851
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0769 0.1159 0.1703
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0016 0.5
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.1485 0.225 0.225
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0074 0.0098 0.0098
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Entamoeba histolytica cysteine protease, putative 0.1485 0.225 0.5843
Schistosoma mansoni growth hormone secretagogue receptor 0.0057 0.0072 0.0072
Plasmodium falciparum serine repeat antigen 1 0.0769 0.1159 0.3009
Giardia lamblia Cysteine protease 0.0769 0.1159 0.1703
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0769 0.1159 0.1703
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2534 0.3851 0.5661
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0072 0.0072
Entamoeba histolytica cysteine proteinase, putative 0.1485 0.225 0.5843
Leishmania major cathepsin L-like protease 0.51 0.7766 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.51 0.7766 1
Onchocerca volvulus 0.0057 0.0072 0.0113
Echinococcus multilocularis neuropeptides capa receptor 0.0057 0.0072 0.0072
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0016 0.0023
Echinococcus granulosus g protein coupled receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0715 0.1077 0.1077
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0057 0.0072 0.0072
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0769 0.1159 0.1159
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0057 0.0072 0.0072
Loa Loa (eye worm) 6-phosphofructokinase 0.0085 0.0115 0.0115
Echinococcus multilocularis cathepsin l cysteine peptidase 0.2534 0.3851 0.3851
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0769 0.1159 0.3009
Loa Loa (eye worm) ctsf protein 0.2534 0.3851 0.3851
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0085 0.0115 0.0148
Echinococcus multilocularis neuropeptide receptor A26 0.0057 0.0072 0.0072
Echinococcus granulosus 7TM GPCR rhodopsin 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.2534 0.3851 0.5661
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0016 0.0023
Loa Loa (eye worm) hypothetical protein 0.0769 0.1159 0.1159
Echinococcus granulosus cathepsin l1 0.2534 0.3851 0.3851
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0054 0.008
Schistosoma mansoni neuropeptide receptor 0.0057 0.0072 0.0072
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0016 0.0016
Giardia lamblia Cathepsin B precursor 0.0769 0.1159 0.1703
Giardia lamblia Cathepsin B precursor 0.4469 0.6803 1
Entamoeba histolytica cysteine protease, putative 0.1485 0.225 0.5843
Echinococcus granulosus lamin 0.0029 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0769 0.1159 0.1703
Plasmodium falciparum serine repeat antigen 5 0.0769 0.1159 0.3009
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0006
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0049 0.0071
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.6564 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1485 0.225 0.3308
Giardia lamblia Cathepsin L-like protease 0.0769 0.1159 0.1703
Loa Loa (eye worm) hypothetical protein 0.0769 0.1159 0.1159
Loa Loa (eye worm) hypothetical protein 0.2534 0.3851 0.3851
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0769 0.1159 0.3009
Toxoplasma gondii cathepsin CPL 0.2534 0.3851 0.5661
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0769 0.1159 0.1159
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.51 0.7766 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0034 0.0034
Trichomonas vaginalis phosphofructokinase, putative 0.0023 0.002 0.003
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0057 0.0072 0.0072
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0029 0.0029
Trichomonas vaginalis phosphofructokinase, putative 0.0023 0.002 0.003
Onchocerca volvulus 0.0057 0.0072 0.0113
Trichomonas vaginalis CAMK family protein kinase 0.0037 0.0041 0.006
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0054 0.008
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0057 0.0072 0.0072
Onchocerca volvulus 0.2534 0.3851 1
Brugia malayi Papain family cysteine protease containing protein 0.1485 0.225 0.225
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.4469 0.6803 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0057 0.0072 0.0072
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1485 0.225 0.225
Loa Loa (eye worm) papain family cysteine protease containing protein 0.2534 0.3851 0.3851
Echinococcus granulosus neuropeptide s receptor 0.0057 0.0072 0.0072
Entamoeba histolytica cysteine protease, putative 0.1485 0.225 0.5843
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2534 0.3851 0.5661
Onchocerca volvulus 0.0057 0.0072 0.0113
Entamoeba histolytica cysteine proteinase, putative 0.1819 0.276 0.7166
Brugia malayi acetyltransferase, GNAT family protein 0.0154 0.022 0.022
Toxoplasma gondii exonuclease III APE 0.002 0.0016 0.0023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0769 0.1159 0.1703
Echinococcus multilocularis g protein coupled receptor 0.0057 0.0072 0.0072
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0085 0.0115 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0016 0.0016
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0049 0.0126
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2534 0.3851 0.5661
Trichomonas vaginalis conserved hypothetical protein 0.0769 0.1159 0.1703
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Echinococcus multilocularis neuropeptide Y receptor 0.0057 0.0072 0.0072
Leishmania major cathepsin L-like protease 0.2534 0.3851 0.4959
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0016 0.0016
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0057 0.0072 0.0072
Giardia lamblia Cysteine protease 0.0769 0.1159 0.1703
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1485 0.225 0.3308
Entamoeba histolytica cysteine proteinase, putative 0.1485 0.225 0.5843
Schistosoma mansoni hypothetical protein 0.0057 0.0072 0.0072
Entamoeba histolytica cysteine protease, putative 0.0769 0.1159 0.3009
Schistosoma mansoni biogenic amine (5HT) receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.1819 0.276 0.276
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.6564 1 1
Schistosoma mansoni neuropeptide F-like receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0769 0.1159 0.1159
Onchocerca volvulus 0.0057 0.0072 0.0113
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0057 0.0072 0.0072
Entamoeba histolytica cysteine proteinase, putative 0.2534 0.3851 1
Trypanosoma cruzi cysteine peptidase, putative 0.51 0.7766 0.7766
Echinococcus granulosus biogenic amine 5HT receptor 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2534 0.3851 0.5661
Onchocerca volvulus 0.0057 0.0072 0.0113
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Trypanosoma brucei cysteine peptidase C (CPC) 0.4469 0.6803 0.876
Trypanosoma cruzi polo-like protein kinase, putative 0.0074 0.0098 0.0098
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0072 0.0072
Loa Loa (eye worm) neuropeptide F receptor 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2534 0.3851 0.5661
Brugia malayi hypothetical protein 0.0057 0.0072 0.0072
Echinococcus granulosus cathepsin b 0.6564 1 1
Toxoplasma gondii phosphofructokinase PFKII 0.0023 0.002 0.003
Giardia lamblia Cathepsin L precursor 0.0769 0.1159 0.1703
Plasmodium vivax serine-repeat antigen (SERA) 0.0769 0.1159 0.3009
Onchocerca volvulus 0.0057 0.0072 0.0113
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0057 0.0072 0.0072
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0006 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0028
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0057 0.0072 0.0072
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0057 0.0072 0.0072
Schistosoma mansoni ap endonuclease 0.002 0.0016 0.0016
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0074 0.0098 0.0126
Echinococcus granulosus histone acetyltransferase KAT2B 0.015 0.0214 0.0214
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0054 0.0054
Brugia malayi cathepsin L-like precursor 0.1819 0.276 0.276
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0769 0.1159 0.1703
Plasmodium vivax unspecified product 0.0769 0.1159 0.3009
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0016 0.0041
Brugia malayi cathepsin L-like cysteine proteinase 0.0769 0.1159 0.1159
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0054 0.008
Echinococcus multilocularis cathepsin L 0.0769 0.1159 0.1159
Brugia malayi larval opioid receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) G-protein coupled receptor 0.0057 0.0072 0.0072
Plasmodium vivax serine-repeat antigen (SERA) 0.0769 0.1159 0.3009
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0769 0.1159 0.1703
Onchocerca volvulus 0.0057 0.0072 0.0113
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0769 0.1159 0.1159
Echinococcus granulosus somatostatin receptor 0.0057 0.0072 0.0072
Schistosoma mansoni kinase 0.0038 0.0043 0.0043
Loa Loa (eye worm) TYRA-2 protein 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Echinococcus granulosus neuropeptide receptor A26 0.0057 0.0072 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.0074 0.0098 0.0098
Brugia malayi AKH receptor 0.0057 0.0072 0.0072
Plasmodium falciparum cysteine proteinase falcipain 2b 0.2534 0.3851 1
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0769 0.1159 0.1703
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0769 0.1159 0.3009
Brugia malayi hypothetical protein 0.0057 0.0072 0.0072
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0769 0.1159 0.1159
Giardia lamblia Cathepsin L precursor 0.0769 0.1159 0.1703
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0016 0.0041
Toxoplasma gondii cathepsin CPC1 0.0769 0.1159 0.1703
Giardia lamblia Encystation-specific protease 0.0769 0.1159 0.1703
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1485 0.225 0.2898
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0057 0.0072 0.0113
Schistosoma mansoni neuropeptide receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.51 0.7766 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0034 0.0034
Giardia lamblia Hypothetical protein 0.0769 0.1159 0.1703
Echinococcus multilocularis sex peptide receptor 0.0057 0.0072 0.0072
Echinococcus multilocularis cysteine protease 0.2534 0.3851 0.3851
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.6564 1 1
Entamoeba histolytica cysteine protease, putative 0.0769 0.1159 0.3009
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Echinococcus multilocularis serotonin receptor 0.0057 0.0072 0.0072
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0057 0.0072 0.0072
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0769 0.1159 0.3009
Giardia lamblia Kinase, PLK 0.0074 0.0098 0.0144
Giardia lamblia Cathepsin B precursor 0.4469 0.6803 1
Schistosoma mansoni neuropeptide receptor 0.0057 0.0072 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0769 0.1159 0.1703
Brugia malayi neuropeptide F receptor 0.0057 0.0072 0.0072
Echinococcus multilocularis cathepsin b 0.6564 1 1
Schistosoma mansoni opsin-like receptor 0.0057 0.0072 0.0072
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0074 0.0098 0.0098
Schistosoma mansoni cathepsin B (C01 family) 0.0769 0.1159 0.1159
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0074 0.0098 0.0098
Schistosoma mansoni adenoreceptor 0.0057 0.0072 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.51 0.7766 1
Loa Loa (eye worm) cysteine protease 0.2534 0.3851 0.3851
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.4469 0.6803 0.6803
Brugia malayi serine/threonine-protein kinase plk-2 0.0074 0.0098 0.0098
Brugia malayi GnHR receptor homolog 0.0057 0.0072 0.0072
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0057 0.0072 0.0072
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0057 0.0072 0.0072
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0072 0.0072
Plasmodium falciparum serine repeat antigen 7 0.0769 0.1159 0.3009
Entamoeba histolytica cysteine protease, putative 0.1485 0.225 0.5843
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2534 0.3851 0.5661
Schistosoma mansoni amine GPCR 0.0057 0.0072 0.0072
Trichomonas vaginalis phosphofructokinase, putative 0.0023 0.002 0.003
Entamoeba histolytica cysteine protease, putative 0.1485 0.225 0.5843
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0057 0.0072 0.0072
Trichomonas vaginalis CAMK family protein kinase 0.0074 0.0098 0.0144
Echinococcus granulosus intermediate filament protein 0.0029 0.0029 0.0029
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0769 0.1159 0.1159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0769 0.1159 0.1703
Onchocerca volvulus 0.0252 0.037 0.0891
Giardia lamblia Cathepsin L precursor 0.0769 0.1159 0.1703
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0154 0.022 0.022
Brugia malayi cathepsin Z-like cysteine proteinase 0.0769 0.1159 0.1159
Brugia malayi Pre-SET motif family protein 0.0221 0.0323 0.0323
Brugia malayi Melatonin receptor type 1A 0.0057 0.0072 0.0072
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0057 0.0072 0.0072
Leishmania major cathepsin L-like protease 0.2534 0.3851 0.4959
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0769 0.1159 0.1159
Schistosoma mansoni biogenic amine receptor 0.0057 0.0072 0.0072
Entamoeba histolytica phosphofructokinase, putative 0.0085 0.0115 0.0299
Onchocerca volvulus 0.2534 0.3851 1
Giardia lamblia Cathepsin B precursor 0.0769 0.1159 0.1703
Schistosoma mansoni 6-phosphofructokinase 0.0085 0.0115 0.0115
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0769 0.1159 0.3009
Plasmodium vivax 6-phosphofructokinase, putative 0.0023 0.002 0.0053
Plasmodium falciparum serine repeat antigen 9 0.0769 0.1159 0.3009
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0769 0.1159 0.1703
Onchocerca volvulus 0.0057 0.0072 0.0113
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.6564 1 1
Brugia malayi Cathepsin L-like precursor 0.2534 0.3851 0.3851
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0049 0.0126
Echinococcus granulosus biogenic amine 5HT receptor 0.0057 0.0072 0.0072
Giardia lamblia Cathepsin B precursor 0.0769 0.1159 0.1703
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Trypanosoma cruzi cruzipain precursor, putative 0.51 0.7766 0.7766
Brugia malayi intermediate filament protein 0.0029 0.0029 0.0029
Trypanosoma cruzi cysteine peptidase, putative 0.51 0.7766 0.7766
Trypanosoma cruzi major cysteine proteinase, putative 0.3335 0.5074 0.5074
Trypanosoma cruzi polo-like protein kinase, putative 0.0074 0.0098 0.0098
Plasmodium falciparum serine repeat antigen 8 0.0769 0.1159 0.3009
Leishmania major cathepsin L-like protease 0.51 0.7766 1
Giardia lamblia Hypothetical protein 0.0769 0.1159 0.1703
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0085 0.0115 0.0115
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2534 0.3851 0.5661
Plasmodium falciparum cysteine proteinase falcipain 1 0.1485 0.225 0.5843
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0057 0.0072 0.0072
Trypanosoma cruzi cysteine protease, putative 0.1485 0.225 0.225
Brugia malayi hypothetical protein 0.0057 0.0072 0.0072
Echinococcus granulosus alpha 1A adrenergic receptor 0.0057 0.0072 0.0072
Echinococcus multilocularis cathepsin l cysteine peptidase 0.2534 0.3851 0.3851
Brugia malayi G-protein coupled receptor 0.0057 0.0072 0.0072
Schistosoma mansoni amine GPCR 0.0057 0.0072 0.0072
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0769 0.1159 0.3009
Echinococcus multilocularis lamin 0.0029 0.0029 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Entamoeba histolytica cysteine protease, putative 0.1485 0.225 0.5843
Echinococcus granulosus neuropeptide Y receptor 0.0057 0.0072 0.0072
Echinococcus multilocularis dro:myosuppressin receptor 0.0057 0.0072 0.0072
Toxoplasma gondii preprocathepsin c precursor, putative 0.0769 0.1159 0.1703
Plasmodium vivax vivapain-2 0.2534 0.3851 1
Entamoeba histolytica cysteine protease, putative 0.1485 0.225 0.5843
Plasmodium vivax unspecified product 0.0715 0.1077 0.2796
Echinococcus granulosus fmrfamide receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Leishmania major cathepsin L-like protease 0.2534 0.3851 0.4959
Echinococcus multilocularis neuropeptide receptor 0.0057 0.0072 0.0072
Schistosoma mansoni cathepsin F (C01 family) 0.2534 0.3851 0.3851
Echinococcus granulosus cathepsin L cysteine protease 0.1485 0.225 0.225
Onchocerca volvulus Serine\/threonine kinase homolog 0.0074 0.0098 0.0181
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0034 0.0049
Loa Loa (eye worm) neuropeptide F receptor 0.0057 0.0072 0.0072
Brugia malayi Pre-SET motif family protein 0.0032 0.0034 0.0034
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.6564 1 1
Loa Loa (eye worm) hypothetical protein 0.0769 0.1159 0.1159
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0057 0.0072 0.0072
Echinococcus multilocularis orexin receptor type 2 0.0057 0.0072 0.0072
Echinococcus granulosus sex peptide receptor 0.0057 0.0072 0.0072
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0016 0.0016
Onchocerca volvulus 0.0057 0.0072 0.0113
Trichomonas vaginalis CAMK family protein kinase 0.0074 0.0098 0.0144
Echinococcus multilocularis serotonin receptor 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2534 0.3851 0.5661
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0072 0.0072
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0023 0.002 0.5
Brugia malayi Papain family cysteine protease containing protein 0.0769 0.1159 0.1159
Brugia malayi Dopamine receptor 0.0057 0.0072 0.0072
Schistosoma mansoni amine GPCR 0.0057 0.0072 0.0072
Echinococcus multilocularis cathepsin L cysteine protease 0.2534 0.3851 0.3851
Giardia lamblia Cathepsin B precursor 0.4469 0.6803 1
Onchocerca volvulus 0.0057 0.0072 0.0113
Leishmania major cathepsin L-like protease 0.2534 0.3851 0.4959
Echinococcus multilocularis 6 phosphofructokinase 0.0085 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Loa Loa (eye worm) phosphofructokinase 0.0085 0.0115 0.0115
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.51 0.7766 1
Entamoeba histolytica cysteine protease, putative 0.0769 0.1159 0.3009
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1485 0.225 0.225
Brugia malayi cathepsin Z-like cysteine proteinase 0.0769 0.1159 0.1159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0769 0.1159 0.1703
Schistosoma mansoni neuropeptide receptor 0.0057 0.0072 0.0072
Schistosoma mansoni ap endonuclease 0.002 0.0016 0.0016
Mycobacterium ulcerans 6-phosphofructokinase 0.0085 0.0115 1
Schistosoma mansoni lamin 0.0029 0.0029 0.0029
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0034 0.0034
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0009 0.0009
Brugia malayi Papain family cysteine protease containing protein 0.0769 0.1159 0.1159
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0016 0.002
Onchocerca volvulus 0.2534 0.3851 1
Trichomonas vaginalis CAMK family protein kinase 0.0074 0.0098 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2534 0.3851 0.5661
Echinococcus multilocularis neuropeptide receptor 0.0057 0.0072 0.0072
Giardia lamblia Cathepsin L precursor 0.0769 0.1159 0.1703
Trypanosoma cruzi cysteine peptidase, putative 0.51 0.7766 0.7766
Brugia malayi 6-phosphofructokinase 0.0085 0.0115 0.0115
Plasmodium vivax vivapain-3 0.1485 0.225 0.5843
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.3837 0.5839 0.5839
Echinococcus multilocularis g protein coupled receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Brugia malayi Serotonin receptor 0.0057 0.0072 0.0072
Echinococcus granulosus tm gpcr rhodopsin 0.3837 0.5839 0.5839
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0054 0.008
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0769 0.1159 0.1703
Trypanosoma cruzi cruzipain precursor, putative 0.0715 0.1077 0.1077
Brugia malayi fibroinase precursor 0.0769 0.1159 0.1159
Echinococcus multilocularis fmrfamide receptor 0.0057 0.0072 0.0072
Onchocerca volvulus Neuropeptide F receptor homolog 0.0057 0.0072 0.0113
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Trichomonas vaginalis phosphofructokinase, putative 0.0085 0.0115 0.0169
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Echinococcus multilocularis cathepsin L 0.1485 0.225 0.225
Brugia malayi Tachykinin-like peptides receptor 99D 0.0057 0.0072 0.0072
Schistosoma mansoni cathepsin C 0.0769 0.1159 0.1159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2534 0.3851 0.5661
Brugia malayi hypothetical protein 0.0057 0.0072 0.0072
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0085 0.0115 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Schistosoma mansoni alpha-1 adrenergic receptor 0.0057 0.0072 0.0072
Brugia malayi Cathepsin L-like precursor 0.2534 0.3851 0.3851
Onchocerca volvulus Cathepsin L homolog 0.0769 0.1159 0.2956
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1819 0.276 0.4056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0034 0.0034
Brugia malayi hypothetical protein 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Entamoeba histolytica cysteine protease, putative 0.1485 0.225 0.5843
Entamoeba histolytica cysteine protease, putative 0.1485 0.225 0.5843
Echinococcus multilocularis fmrfamide receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) G-protein coupled receptor 0.0057 0.0072 0.0072
Echinococcus granulosus tm gpcr rhodopsin 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1819 0.276 0.4056
Schistosoma mansoni cathepsin S (C01 family) 0.0769 0.1159 0.1159
Entamoeba histolytica cysteine proteinase, putative 0.1485 0.225 0.5843
Trichomonas vaginalis phosphofructokinase, putative 0.0085 0.0115 0.0169
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0057 0.0072 0.0072
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0057 0.0072 0.0072
Entamoeba histolytica cysteine protease, putative 0.1485 0.225 0.5843
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.2534 0.3851 0.5661
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2534 0.3851 0.5661
Brugia malayi G-protein coupled receptor 0.0057 0.0072 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.51 0.7766 1
Loa Loa (eye worm) hypothetical protein 0.1819 0.276 0.276
Schistosoma mansoni 6-phosphofructokinase 0.0085 0.0115 0.0115
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2534 0.3851 0.5661
Schistosoma mansoni opsin-like receptor 0.0057 0.0072 0.0072
Schistosoma mansoni biogenic amine (5HT) receptor 0.0057 0.0072 0.0072
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0054 0.0141
Trichomonas vaginalis phosphofructokinase, putative 0.0023 0.002 0.003
Brugia malayi cathepsin F-like cysteine proteinase 0.0769 0.1159 0.1159
Schistosoma mansoni intermediate filament proteins 0.0029 0.0029 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.51 0.7766 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0057 0.0072 0.0072
Loa Loa (eye worm) fibroinase 0.2534 0.3851 0.3851
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0769 0.1159 0.1159
Echinococcus multilocularis cathepsin L cysteine protease 0.2534 0.3851 0.3851
Entamoeba histolytica cysteine protease, putative 0.1485 0.225 0.5843
Echinococcus granulosus cysteine protease 0.1485 0.225 0.225
Brugia malayi G protein-coupled receptor 0.0057 0.0072 0.0072
Brugia malayi Cathepsin L-like precursor 0.2534 0.3851 0.3851
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0013 0.0006 0.0006
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0057 0.0072 0.0072
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0769 0.1159 0.3009
Echinococcus granulosus tachykinin peptides receptor 99D 0.0057 0.0072 0.0072
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0057 0.0072 0.0072
Plasmodium falciparum serine repeat antigen 6 0.0769 0.1159 0.3009
Brugia malayi Cathepsin L-like precursor 0.1819 0.276 0.276
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0057 0.0072 0.0072
Entamoeba histolytica cysteine protease, putative 0.0769 0.1159 0.3009
Echinococcus granulosus neuropeptide receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Echinococcus granulosus cathepsin b 0.6564 1 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0016 0.0016
Loa Loa (eye worm) acetyltransferase 0.0154 0.022 0.022
Plasmodium falciparum cysteine proteinase falcipain 2a 0.2534 0.3851 1
Echinococcus granulosus lamin dm0 0.0029 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Echinococcus multilocularis neuropeptide FF receptor 2 0.0057 0.0072 0.0072
Giardia lamblia Cathepsin B precursor 0.0769 0.1159 0.1703
Onchocerca volvulus Cathepsin L homolog 0.2534 0.3851 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0769 0.1159 0.1159
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0029 0.0029
Onchocerca volvulus 0.0057 0.0072 0.0113
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0057 0.0072 0.0072
Schistosoma mansoni myosin xvIII 0.0057 0.0072 0.0072
Brugia malayi phosphofructokinase 0.0085 0.0115 0.0115
Brugia malayi putative neuropeptide receptor 0.0057 0.0072 0.0072
Onchocerca volvulus 0.2534 0.3851 1
Echinococcus granulosus G protein coupled receptor 139 0.0057 0.0072 0.0072
Echinococcus multilocularis neuropeptide Y receptor 0.0057 0.0072 0.0072
Schistosoma mansoni hypothetical protein 0.0057 0.0072 0.0072
Toxoplasma gondii cathepsin CPC2 0.0769 0.1159 0.1703
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0769 0.1159 0.1159
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Entamoeba histolytica cysteine protease, putative 0.1485 0.225 0.5843
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Brugia malayi follicle stimulating hormone receptor 0.0057 0.0072 0.0072
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1485 0.225 0.2898
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0715 0.1077 0.1077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2534 0.3851 0.5661
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.2534 0.3851 0.5661
Loa Loa (eye worm) hypothetical protein 0.0769 0.1159 0.1159
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0769 0.1159 0.1159
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0023 0.002 0.003
Brugia malayi hypothetical protein 0.0057 0.0072 0.0072
Echinococcus multilocularis g-protein coupled receptor 0.0057 0.0072 0.0072
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0769 0.1159 0.1703
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0016 0.002
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0769 0.1159 0.3009
Echinococcus granulosus cathepsin L 0.1485 0.225 0.225
Brugia malayi Cathepsin L-like precursor 0.2534 0.3851 0.3851
Echinococcus granulosus neuropeptide receptor 0.0057 0.0072 0.0072
Giardia lamblia Cathepsin L precursor 0.0769 0.1159 0.1703
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Leishmania major ATP-dependent phosphofructokinase 0.0085 0.0115 0.0148
Trichomonas vaginalis CAMK family protein kinase 0.0074 0.0098 0.0144
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0769 0.1159 0.1703
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0769 0.1159 0.1703
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Brugia malayi Cathepsin L-like precursor 0.2534 0.3851 0.3851
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0769 0.1159 0.1703
Loa Loa (eye worm) melatonin receptor type 1A 0.0057 0.0072 0.0072
Echinococcus multilocularis neuropeptide s receptor 0.0057 0.0072 0.0072
Echinococcus multilocularis rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Entamoeba histolytica cysteine proteinase 2 0.1485 0.225 0.5843
Schistosoma mansoni neuropeptide F-like receptor 0.0057 0.0072 0.0072
Entamoeba histolytica phosphofructokinase, putative 0.0085 0.0115 0.0299
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0023 0.002 0.0458
Brugia malayi neuropeptide F receptor 0.0057 0.0072 0.0072
Entamoeba histolytica cysteine protease, putative 0.0769 0.1159 0.3009
Schistosoma mansoni amine GPCR 0.0057 0.0072 0.0072
Schistosoma mansoni cathepsin F (C01 family) 0.1819 0.276 0.276
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0769 0.1159 0.3009
Giardia lamblia Cysteine protease 0.0769 0.1159 0.1703
Plasmodium falciparum cysteine proteinase falcipain 3 0.2534 0.3851 1
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0769 0.1159 0.3009
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0016 0.0041
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Echinococcus granulosus 7tm_1 domain containing protein 0.0057 0.0072 0.0072
Entamoeba histolytica serine/threonine protein kinase, putative 0.0074 0.0098 0.0254
Echinococcus granulosus g protein coupled receptor 0.0057 0.0072 0.0072
Onchocerca volvulus 0.0057 0.0072 0.0113
Brugia malayi G protein-coupled receptor F59B2.13 0.0057 0.0072 0.0072
Trypanosoma cruzi major cysteine proteinase, putative 0.0769 0.1159 0.1159
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0034 0.0034
Trichomonas vaginalis phosphofructokinase, putative 0.0023 0.002 0.003
Onchocerca volvulus 0.0057 0.0072 0.0113
Echinococcus multilocularis g protein coupled receptor 0.0057 0.0072 0.0072
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0023 0.002 0.0053
Brugia malayi cathepsin L precursor 0.0769 0.1159 0.1159
Onchocerca volvulus 0.0057 0.0072 0.0113
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0032 0.0032
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0057 0.0072 0.0072
Brugia malayi Papain family cysteine protease containing protein 0.0769 0.1159 0.1159
Entamoeba histolytica hypothetical protein 0.0769 0.1159 0.3009
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Brugia malayi putative neuropeptide receptor NPR1 0.0057 0.0072 0.0072
Trichomonas vaginalis phosphofructokinase, putative 0.0023 0.002 0.003
Echinococcus granulosus neuropeptides capa receptor 0.0057 0.0072 0.0072
Brugia malayi 6-phosphofructokinase 0.0085 0.0115 0.0115
Loa Loa (eye worm) cathepsin B 0.4469 0.6803 0.6803
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Brugia malayi hypothetical protein 0.0057 0.0072 0.0072
Giardia lamblia Cathepsin B precursor 0.0769 0.1159 0.1703
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0057 0.0072 0.0072
Onchocerca volvulus Cathepsin F homolog 0.2534 0.3851 1
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0016 0.0023
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0085 0.0115 0.5
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0034 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.51 0.7766 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Brugia malayi Cathepsin L-like cysteine proteinase 0.1819 0.276 0.276
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Brugia malayi ORL1-like opioid receptor 0.0057 0.0072 0.0072
Brugia malayi hypothetical protein 0.0057 0.0072 0.0072
Entamoeba histolytica cysteine proteinase, putative 0.1485 0.225 0.5843
Trichomonas vaginalis phosphofructokinase, putative 0.0085 0.0115 0.0169
Echinococcus multilocularis G-protein coupled receptor, putative 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0715 0.1077 0.1077
Echinococcus granulosus neuropeptide Y receptor 0.0057 0.0072 0.0072
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.4469 0.6803 0.876
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0769 0.1159 0.3009
Loa Loa (eye worm) hypothetical protein 0.0057 0.0072 0.0072
Leishmania major cysteine peptidase A (CPA) 0.2534 0.3851 0.4959
Schistosoma mansoni biogenic amine receptor 0.0057 0.0072 0.0072
Echinococcus multilocularis cathepsin b 0.6564 1 1
Onchocerca volvulus 0.0057 0.0072 0.0113
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2534 0.3851 0.5661
Entamoeba histolytica phosphofructokinase, putative 0.0085 0.0115 0.0299
Brugia malayi Cathepsin L-like precursor 0.2534 0.3851 0.3851
Trichomonas vaginalis CAMK family protein kinase 0.0074 0.0098 0.0144
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0057 0.0072 0.0072
Schistosoma mansoni histamine h1 receptor 0.0057 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0715 0.1077 0.1077
Echinococcus granulosus serotonin receptor 0.0057 0.0072 0.0072
Brugia malayi cathepsin F-like cysteine proteinase 0.0715 0.1077 0.1077
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1485 0.225 0.225
Entamoeba histolytica cysteine protease, putative 0.2534 0.3851 1
Leishmania major cathepsin L-like protease 0.51 0.7766 1
Schistosoma mansoni biogenic amine receptor 0.0057 0.0072 0.0072
Giardia lamblia Cysteine protease 0.0769 0.1159 0.1703
Brugia malayi Dopamine receptor protein 2 0.0057 0.0072 0.0072
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0057 0.0072 0.0072
Trichomonas vaginalis set domain proteins, putative 0.0252 0.037 0.0543
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.51 0.7766 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0057 0.0072 0.0072
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0154 0.022 0.022
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0769 0.1159 0.1703
Echinococcus granulosus rhodopsin orphan GPCR 0.0057 0.0072 0.0072
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0057 0.0072 0.0072
Plasmodium vivax 6-phosphofructokinase, putative 0.0023 0.002 0.0053
Echinococcus granulosus dro:myosuppressin receptor 0.0057 0.0072 0.0072
Onchocerca volvulus 0.0769 0.1159 0.2956
Onchocerca volvulus 0.0032 0.0034 0.0012
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0023 0.002 0.0053
Echinococcus granulosus cathepsin L 0.0769 0.1159 0.1159
Onchocerca volvulus 0.2534 0.3851 1
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0023 0.002 0.5
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0769 0.1159 0.1159
Echinococcus multilocularis lamin dm0 0.0029 0.0029 0.0029
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0715 0.1077 0.1077
Brugia malayi Papain family cysteine protease containing protein 0.2534 0.3851 0.3851
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0769 0.1159 0.1703
Trypanosoma cruzi cysteine peptidase, putative 0.0715 0.1077 0.1077

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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