Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1954 | 0.1273 |
Onchocerca volvulus | 0.0223 | 0.8075 | 1 | |
Trypanosoma brucei | cytochrome P450, putative | 0.0068 | 0.0781 | 0.5 |
Brugia malayi | Sema domain containing protein | 0.0093 | 0.1954 | 0.1273 |
Loa Loa (eye worm) | plexin A | 0.0264 | 1 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0052 | 0 | 0.5 |
Brugia malayi | Plexin repeat family protein | 0.0223 | 0.8075 | 0.7912 |
Echinococcus multilocularis | plexin a4 | 0.0264 | 1 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0068 | 0.0781 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1954 | 0.1273 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0068 | 0.0781 | 0.5 |
Leishmania major | cytochrome p450-like protein | 0.0068 | 0.0781 | 0.5 |
Brugia malayi | hypothetical protein | 0.0093 | 0.1954 | 0.1273 |
Brugia malayi | hypothetical protein | 0.0093 | 0.1954 | 0.1273 |
Schistosoma mansoni | plexin | 0.013 | 0.3682 | 0.2822 |
Brugia malayi | Sema domain containing protein | 0.0093 | 0.1954 | 0.1273 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1954 | 0.1273 |
Echinococcus granulosus | plexin a4 | 0.0264 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.3682 | 0.3147 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0068 | 0.0781 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1954 | 0.1273 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1954 | 0.1273 |
Loa Loa (eye worm) | hypothetical protein | 0.0223 | 0.8075 | 0.7912 |
Loa Loa (eye worm) | sema domain-containing protein | 0.0093 | 0.1954 | 0.1273 |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.3682 | 0.2822 |
Schistosoma mansoni | plexin | 0.0223 | 0.8075 | 1 |
Loa Loa (eye worm) | sema domain-containing protein | 0.0093 | 0.1954 | 0.1273 |
Entamoeba histolytica | tyrosin kinase, putative | 0.0052 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.1954 | 0.1273 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.