Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Carboxylesterase family protein | 0.0132 | 0.5741 | 0.5788 |
Brugia malayi | GSG2 | 0.0202 | 0.9918 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0132 | 0.5741 | 0.5788 |
Echinococcus granulosus | acetylcholinesterase | 0.0132 | 0.5741 | 0.5788 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0157 | 0.7243 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0132 | 0.5741 | 0.5788 |
Echinococcus granulosus | serine:threonine protein kinase haspin | 0.0202 | 0.9918 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase haspin | 0.0202 | 0.9918 | 1 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK2 protein kinase | 0.0157 | 0.7243 | 0.7243 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0132 | 0.5741 | 0.5741 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0157 | 0.7243 | 0.7302 |
Echinococcus multilocularis | dual specificity | 0.0157 | 0.7243 | 0.7302 |
Echinococcus granulosus | serine:threonine protein kinase haspin | 0.0202 | 0.9918 | 1 |
Echinococcus multilocularis | dual specificity | 0.0157 | 0.7243 | 0.7302 |
Echinococcus multilocularis | acetylcholinesterase | 0.0132 | 0.5741 | 0.5788 |
Trypanosoma brucei | dual specificity tyrosine-phosphorylation-regulated kinase 2, putative | 0.0157 | 0.7243 | 1 |
Echinococcus granulosus | serine:threonine protein kinase haspin | 0.0202 | 0.9918 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0157 | 0.7243 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0157 | 0.7243 | 1 |
Trypanosoma cruzi | dual specificity tyrosine-phosphorylation-regulated kinase 2, putative | 0.0157 | 0.7243 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0157 | 0.7243 | 1 |
Plasmodium vivax | serine/threonine protein kinase KIN, putative | 0.0036 | 0 | 0.5 |
Toxoplasma gondii | cell-cycle-associated protein kinase DYRK2, putative | 0.0157 | 0.7243 | 0.5 |
Loa Loa (eye worm) | haspin protein kinase | 0.0202 | 0.9918 | 0.9918 |
Loa Loa (eye worm) | haspin protein kinase | 0.0202 | 0.9918 | 0.9918 |
Brugia malayi | hypothetical protein | 0.0202 | 0.9918 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0157 | 0.7243 | 1 |
Plasmodium falciparum | MO15-related protein kinase | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0202 | 0.9918 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0157 | 0.7243 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.5741 | 0.5741 |
Echinococcus granulosus | dual specificity | 0.0157 | 0.7243 | 0.7302 |
Echinococcus granulosus | dual specificity | 0.0157 | 0.7243 | 0.7302 |
Echinococcus granulosus | dual specificity | 0.0157 | 0.7243 | 0.7302 |
Echinococcus multilocularis | serine:threonine protein kinase haspin | 0.0202 | 0.9918 | 1 |
Plasmodium vivax | cyclin dependent kinase 7 (cdk7), putative | 0.0036 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0132 | 0.5741 | 0.5788 |
Giardia lamblia | Kinase, CMGC DYRK | 0.0157 | 0.7243 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0157 | 0.7243 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0132 | 0.5741 | 0.5741 |
Brugia malayi | Dual-specificity tyrosine-phosphorylation regulated kinase 2 | 0.0157 | 0.7243 | 0.7302 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0132 | 0.5741 | 0.5788 |
Echinococcus multilocularis | acetylcholinesterase | 0.0132 | 0.5741 | 0.5788 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.5741 | 0.5741 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0157 | 0.7243 | 1 |
Echinococcus multilocularis | dual specificity | 0.0157 | 0.7243 | 0.7302 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0132 | 0.5741 | 0.5788 |
Leishmania major | protein kinase, putative,dual-specificity protein kinase, putative | 0.0157 | 0.7243 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.