Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.3824 | 0.8726 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.3824 | 0.8726 |
Echinococcus granulosus | cathepsin l1 | 0.0119 | 0.0951 | 0.0951 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0119 | 0.0951 | 0.0951 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0557 | 1 | 1 |
Onchocerca volvulus | 0.0119 | 0.0951 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0557 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0088 | 0.0303 | 0.0691 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.3824 | 0.8726 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Echinococcus multilocularis | cathepsin b | 0.0557 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0119 | 0.0951 | 0.0951 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.3824 | 0.8726 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Echinococcus granulosus | cathepsin l1 | 0.0088 | 0.0303 | 0.0303 |
Brugia malayi | Cathepsin L-like precursor | 0.0119 | 0.0951 | 0.0951 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0285 | 0.4382 | 0.4382 |
Onchocerca volvulus | 0.0119 | 0.0951 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Plasmodium vivax | vivapain-2 | 0.0119 | 0.0951 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0119 | 0.0951 | 0.0951 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0119 | 0.0951 | 0.0669 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0119 | 0.0951 | 0.0669 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0258 | 0.3824 | 0.3824 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0119 | 0.0951 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Onchocerca volvulus | 0.0119 | 0.0951 | 1 | |
Brugia malayi | cathepsin L-like precursor | 0.0088 | 0.0303 | 0.0303 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Leishmania major | cathepsin L-like protease | 0.0258 | 0.3824 | 0.8373 |
Brugia malayi | Cathepsin L-like precursor | 0.0088 | 0.0303 | 0.0303 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.3824 | 0.8726 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0285 | 0.4382 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0181 | 0.2224 | 0.2224 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0951 | 0.0669 |
Onchocerca volvulus | 0.0119 | 0.0951 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0119 | 0.0951 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0088 | 0.0303 | 0.0303 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0119 | 0.0951 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Loa Loa (eye worm) | fibroinase | 0.0119 | 0.0951 | 0.0669 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Onchocerca volvulus | 0.0119 | 0.0951 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Echinococcus granulosus | cathepsin b | 0.0557 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0285 | 0.4382 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0088 | 0.0303 | 0.0303 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0285 | 0.4382 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.3824 | 0.8726 |
Onchocerca volvulus | Cathepsin L homolog | 0.0119 | 0.0951 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0088 | 0.0303 | 0.0303 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0119 | 0.0951 | 1 |
Onchocerca volvulus | 0.0119 | 0.0951 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.3824 | 0.8726 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0088 | 0.0303 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0119 | 0.0951 | 0.0951 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Leishmania major | cathepsin L-like protease | 0.0258 | 0.3824 | 0.8373 |
Echinococcus multilocularis | cysteine protease | 0.0119 | 0.0951 | 0.0951 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0285 | 0.4382 | 0.4382 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Entamoeba histolytica | cysteine protease, putative | 0.0119 | 0.0951 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Giardia lamblia | Cathepsin B precursor | 0.0285 | 0.4382 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0119 | 0.0951 | 0.0951 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0119 | 0.0951 | 0.0951 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0557 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0557 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0119 | 0.0951 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.3824 | 0.8726 |
Onchocerca volvulus | Cathepsin F homolog | 0.0119 | 0.0951 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0119 | 0.0951 | 0.0951 |
Brugia malayi | Cathepsin L-like precursor | 0.0119 | 0.0951 | 0.0951 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Echinococcus multilocularis | cysteine protease | 0.0119 | 0.0951 | 0.0951 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.3824 | 0.8726 |
Loa Loa (eye worm) | cysteine protease | 0.0119 | 0.0951 | 0.0669 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.3824 | 0.8726 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0258 | 0.3824 | 0.3824 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0227 | 0.3175 | 0.3175 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Toxoplasma gondii | cathepsin B | 0.0285 | 0.4382 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0285 | 0.4382 | 0.5 |
Loa Loa (eye worm) | cathepsin B | 0.0285 | 0.4382 | 0.4207 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0557 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0119 | 0.0951 | 0.0951 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0258 | 0.3824 | 0.8726 |
Brugia malayi | Cathepsin L-like precursor | 0.0119 | 0.0951 | 0.0951 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0557 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0119 | 0.0951 | 1 |
Plasmodium vivax | vivapain-2 | 0.0119 | 0.0951 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0119 | 0.0951 | 0.0951 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0119 | 0.0951 | 0.0951 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0258 | 0.3824 | 0.3824 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Brugia malayi | Cathepsin L-like precursor | 0.0119 | 0.0951 | 0.0951 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Giardia lamblia | Cathepsin B precursor | 0.0285 | 0.4382 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0258 | 0.3824 | 0.8373 |
Brugia malayi | Cathepsin L-like precursor | 0.0119 | 0.0951 | 0.0951 |
Echinococcus granulosus | cathepsin b | 0.0557 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0119 | 0.0951 | 0.0669 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0088 | 0.0303 | 0.0691 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0258 | 0.3824 | 0.3824 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0119 | 0.0951 | 0.0951 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0557 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0119 | 0.0951 | 0.2171 |
Onchocerca volvulus | 0.0119 | 0.0951 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.