Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0286 | 1 | 1 | |
Mycobacterium ulcerans | diaminopimelate decarboxylase LysA | 0.0175 | 0.491 | 0.5 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0286 | 1 | 1 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0286 | 1 | 1 |
Toxoplasma gondii | diaminopimelate decarboxylase | 0.0175 | 0.491 | 0.5 |
Onchocerca volvulus | 0.0286 | 1 | 1 | |
Brugia malayi | Common central domain of tyrosinase family protein | 0.0286 | 1 | 1 |
Trichomonas vaginalis | diaminopimelate decarboxylase, putative | 0.0175 | 0.491 | 1 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0286 | 1 | 1 |
Onchocerca volvulus | 0.0286 | 1 | 1 | |
Trichomonas vaginalis | ornithine decarboxylase, putative | 0.0175 | 0.491 | 1 |
Schistosoma mansoni | tyrosinase precursor | 0.0286 | 1 | 0.5 |
Trichomonas vaginalis | diaminopimelate decarboxylase, putative | 0.0175 | 0.491 | 1 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0286 | 1 | 1 |
Loa Loa (eye worm) | tyrosinase 1 | 0.0286 | 1 | 1 |
Brugia malayi | Hypothetical tyrosinase-like protein F21C3.2 in chromosome I | 0.0286 | 1 | 1 |
Mycobacterium leprae | PROBABLE DIAMINOPIMELATE DECARBOXYLASE LYSA (DAP DECARBOXYLASE) | 0.0067 | 0 | 0.5 |
Plasmodium falciparum | S-adenosylmethionine decarboxylase/ornithine decarboxylase | 0.0175 | 0.491 | 0.5 |
Mycobacterium tuberculosis | Diaminopimelate decarboxylase LysA (DAP decarboxylase) | 0.0175 | 0.491 | 0.5 |
Onchocerca volvulus | 0.0286 | 1 | 1 | |
Schistosoma mansoni | tyrosinase precursor | 0.0286 | 1 | 0.5 |
Leishmania major | ornithine decarboxylase, putative | 0.0175 | 0.491 | 0.5 |
Giardia lamblia | Ornithine decarboxylase | 0.0175 | 0.491 | 0.5 |
Trypanosoma brucei | ornithine decarboxylase | 0.0175 | 0.491 | 0.5 |
Entamoeba histolytica | ornithine decarboxylase, putative | 0.0175 | 0.491 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0286 | 1 | 1 |
Plasmodium vivax | S-adenosylmethionine decarboxylase-ornithine decarboxylase, putative | 0.0175 | 0.491 | 0.5 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0286 | 1 | 1 |
Trichomonas vaginalis | ornithine decarboxylase, putative | 0.0175 | 0.491 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0286 | 1 | 1 |
Trichomonas vaginalis | pyridoxal-dependent decarboxylase, putative | 0.0175 | 0.491 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.