Detailed information for compound 882365

Basic information

Technical information
  • TDR Targets ID: 882365
  • Name: 3-chloro-4-[(2-ethylphenyl)amino]-1-phenylpyr role-2,5-dione
  • MW: 326.777 | Formula: C18H15ClN2O2
  • H donors: 1 H acceptors: 2 LogP: 4.43 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccccc1NC1=C(Cl)C(=O)N(C1=O)c1ccccc1
  • InChi: 1S/C18H15ClN2O2/c1-2-12-8-6-7-11-14(12)20-16-15(19)17(22)21(18(16)23)13-9-4-3-5-10-13/h3-11,20H,2H2,1H3
  • InChiKey: RDFOXFZXDUDWNQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-chloro-4-[(2-ethylphenyl)amino]-1-phenyl-pyrrole-2,5-dione
  • 3-chloro-4-[(2-ethylphenyl)amino]-1-phenyl-3-pyrroline-2,5-quinone
  • AF-399/14183555
  • ST5189403
  • ZINC00121601

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Loa Loa (eye worm) matrixin family protein 0.0155 0.0788 0.0788
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0197 0.1167 0.1028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Schistosoma mansoni biogenic amine receptor 0.0197 0.1167 0.1028
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0078 0.0098 0.0006
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus multilocularis ceramide glucosyltransferase 0.1182 1 1
Brugia malayi hypothetical protein 0.0197 0.1167 0.1085
Loa Loa (eye worm) ceramide glucosyltransferase 0.1182 1 1
Onchocerca volvulus 0.0197 0.1167 0.0975
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0197 0.1167 0.1167
Echinococcus granulosus G protein coupled receptor 139 0.0197 0.1167 0.1085
Brugia malayi Dopamine receptor protein 2 0.0197 0.1167 0.1085
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0197 0.1167 0.1028
Onchocerca volvulus Neuropeptide F receptor homolog 0.0197 0.1167 0.0975
Echinococcus granulosus neuropeptide s receptor 0.0197 0.1167 0.1085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0197 0.1167 0.1028
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0197 0.1167 0.1085
Echinococcus multilocularis neuropeptide receptor 0.0197 0.1167 0.1085
Schistosoma mansoni neuropeptide receptor 0.0197 0.1167 0.1028
Echinococcus multilocularis allatostatin A receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus granulosus peptide allatostatin:somatostatin 0.0197 0.1167 0.1085
Brugia malayi Dopamine receptor protein 1 0.0197 0.1167 0.1085
Schistosoma mansoni amine GPCR 0.0197 0.1167 0.1028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0197 0.1167 0.1028
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0197 0.1167 0.1085
Echinococcus granulosus neuropeptide receptor A26 0.0197 0.1167 0.1085
Loa Loa (eye worm) neuropeptide F receptor 0.0197 0.1167 0.1167
Echinococcus multilocularis g protein coupled receptor 0.0197 0.1167 0.1085
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0197 0.1167 0.1085
Echinococcus granulosus tm gpcr rhodopsin 0.0197 0.1167 0.1085
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0197 0.1167 0.1085
Brugia malayi larval opioid receptor 0.0197 0.1167 0.1085
Brugia malayi hypothetical protein 0.0197 0.1167 0.1085
Echinococcus granulosus sex peptide receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus multilocularis serotonin receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus granulosus tm gpcr rhodopsin 0.0197 0.1167 0.1085
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0197 0.1167 0.1085
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Brugia malayi putative neuropeptide receptor NPR1 0.0197 0.1167 0.1085
Brugia malayi hypothetical protein 0.0197 0.1167 0.1085
Brugia malayi hypothetical protein 0.0197 0.1167 0.1085
Schistosoma mansoni neuropeptide receptor 0.0197 0.1167 0.1028
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0197 0.1167 0.1028
Onchocerca volvulus 0.0197 0.1167 0.0975
Echinococcus granulosus neuropeptides capa receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0197 0.1167 0.1167
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0197 0.1167 0.1028
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0197 0.1167 0.1028
Brugia malayi G-protein coupled receptor 0.0197 0.1167 0.1085
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0085 0.0164 0.0073
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Brugia malayi hypothetical protein 0.0197 0.1167 0.1085
Schistosoma mansoni adenoreceptor 0.0197 0.1167 0.1028
Echinococcus granulosus orexin receptor type 2 0.0197 0.1167 0.1085
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0197 0.1167 0.1028
Brugia malayi Melatonin receptor type 1A 0.0197 0.1167 0.1085
Brugia malayi Matrixin family protein 0.0155 0.0788 0.0703
Echinococcus multilocularis G protein coupled receptor 139 0.0197 0.1167 0.1085
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0197 0.1167 0.1028
Onchocerca volvulus 0.0197 0.1167 0.0975
Onchocerca volvulus 0.0197 0.1167 0.0975
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0197 0.1167 0.1085
Schistosoma mansoni amine GPCR 0.0197 0.1167 0.1028
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0085 0.0164 0.0009
Echinococcus granulosus neuropeptides capa receptor 0.0197 0.1167 0.1085
Echinococcus granulosus somatostatin receptor 0.0197 0.1167 0.1085
Brugia malayi hypothetical protein 0.0197 0.1167 0.1085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0197 0.1167 0.1028
Echinococcus multilocularis neuropeptide receptor A26 0.0197 0.1167 0.1085
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0197 0.1167 0.1085
Echinococcus granulosus 7TM GPCR rhodopsin 0.0197 0.1167 0.1085
Schistosoma mansoni hypothetical protein 0.0197 0.1167 0.1028
Echinococcus granulosus neuropeptide Y receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Brugia malayi AKH receptor 0.0197 0.1167 0.1085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0197 0.1167 0.1085
Schistosoma mansoni biogenic amine receptor 0.0197 0.1167 0.1028
Echinococcus multilocularis orexin receptor type 2 0.0197 0.1167 0.1085
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0197 0.1167 0.1028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0197 0.1167 0.1028
Onchocerca volvulus 0.0197 0.1167 0.0975
Schistosoma mansoni opsin-like receptor 0.0197 0.1167 0.1028
Schistosoma mansoni hypothetical protein 0.0197 0.1167 0.1028
Echinococcus granulosus tm gpcr rhodopsin 0.0197 0.1167 0.1085
Schistosoma mansoni amine GPCR 0.0197 0.1167 0.1028
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Schistosoma mansoni biogenic amine (5HT) receptor 0.0197 0.1167 0.1028
Brugia malayi neuropeptide F receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus multilocularis rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0197 0.1167 0.1085
Onchocerca volvulus Matrilysin homolog 0.0142 0.0673 0.047
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0197 0.1167 0.1028
Echinococcus granulosus g protein coupled receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) neuropeptide F receptor 0.0197 0.1167 0.1167
Onchocerca volvulus 0.0197 0.1167 0.0975
Schistosoma mansoni biogenic amine (5HT) receptor 0.0197 0.1167 0.1028
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0197 0.1167 0.0975
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0197 0.1167 0.1085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Loa Loa (eye worm) TYRA-2 protein 0.0197 0.1167 0.1167
Schistosoma mansoni hypothetical protein 0.0197 0.1167 0.1028
Echinococcus multilocularis neuropeptide FF receptor 2 0.0197 0.1167 0.1085
Loa Loa (eye worm) G-protein coupled receptor 0.0197 0.1167 0.1167
Schistosoma mansoni histamine h1 receptor 0.0197 0.1167 0.1028
Onchocerca volvulus 0.0197 0.1167 0.0975
Schistosoma mansoni neuropeptide f receptor 76f 0.0197 0.1167 0.1028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0197 0.1167 0.1028
Mycobacterium leprae PROBABLE HYDROLASE 0.0078 0.0098 0.5
Brugia malayi Dopamine receptor 0.0197 0.1167 0.1085
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Brugia malayi hypothetical protein 0.0197 0.1167 0.1085
Schistosoma mansoni neuropeptide receptor 0.0197 0.1167 0.1028
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus granulosus tachykinin peptides receptor 99D 0.0197 0.1167 0.1085
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0197 0.1167 0.1028
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus granulosus ceramide glucosyltransferase 0.1182 1 1
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0085 0.0164 0.0073
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0114 0.0416 0.0328
Echinococcus granulosus fmrfamide receptor 0.0197 0.1167 0.1085
Schistosoma mansoni ceramide glucosyltransferase 0.1182 1 1
Brugia malayi putative neuropeptide receptor 0.0197 0.1167 0.1085
Schistosoma mansoni neuropeptide F-like receptor 0.0197 0.1167 0.1028
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Schistosoma mansoni hypothetical protein 0.0091 0.0213 0.0058
Echinococcus multilocularis neuropeptides capa receptor 0.0197 0.1167 0.1085
Echinococcus granulosus neuropeptide receptor 0.0197 0.1167 0.1085
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.0181 0.1021 0.0879
Brugia malayi Serotonin receptor 0.0197 0.1167 0.1085
Echinococcus granulosus rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Brugia malayi Serotonin receptor 0.0197 0.1167 0.1085
Echinococcus multilocularis neuropeptides capa receptor 0.0197 0.1167 0.1085
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Brugia malayi hypothetical protein 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0197 0.1167 0.1167
Echinococcus multilocularis g-protein coupled receptor 0.0197 0.1167 0.1085
Echinococcus multilocularis sex peptide receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus granulosus serotonin receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus granulosus neuropeptide Y receptor 0.0197 0.1167 0.1085
Brugia malayi G protein-coupled receptor F59B2.13 0.0197 0.1167 0.1085
Schistosoma mansoni amine GPCR 0.0197 0.1167 0.1028
Schistosoma mansoni myosin xvIII 0.0197 0.1167 0.1028
Schistosoma mansoni ceramide glucosyltransferase 0.1182 1 1
Schistosoma mansoni opsin-like receptor 0.0197 0.1167 0.1028
Echinococcus granulosus rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0233 0.1488 0.1409
Onchocerca volvulus 0.0197 0.1167 0.0975
Schistosoma mansoni neuropeptide receptor 0.0197 0.1167 0.1028
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0197 0.1167 0.1167
Echinococcus granulosus biogenic amine 5HT receptor 0.0197 0.1167 0.1085
Schistosoma mansoni opsin-like receptor 0.0197 0.1167 0.1028
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0114 0.0416 0.0328
Schistosoma mansoni neuropeptide F-like receptor 0.0197 0.1167 0.1028
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0197 0.1167 0.1028
Brugia malayi ORL1-like opioid receptor 0.0197 0.1167 0.1085
Onchocerca volvulus 0.0197 0.1167 0.0975
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0197 0.1167 0.1085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0197 0.1167 0.1028
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0197 0.1167 0.1085
Onchocerca volvulus Ceramide glucosyltransferase homolog 0.1182 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Echinococcus granulosus g protein coupled receptor 0.0197 0.1167 0.1085
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0197 0.1167 0.1085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0197 0.1167 0.1028
Echinococcus multilocularis neuropeptide s receptor 0.0197 0.1167 0.1085
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0197 0.1167 0.1085
Echinococcus granulosus neuropeptide FF receptor 2 0.0197 0.1167 0.1085
Echinococcus granulosus allatostatin A receptor 0.0197 0.1167 0.1085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0197 0.1167 0.1028
Onchocerca volvulus 0.0197 0.1167 0.0975
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0077 0.0092 0.0092
Echinococcus multilocularis serotonin receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0072 0.0046 0.5
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0197 0.1167 0.1028
Loa Loa (eye worm) G-protein coupled receptor 0.0197 0.1167 0.1167
Echinococcus multilocularis neuropeptide Y receptor 0.0197 0.1167 0.1085
Brugia malayi Tachykinin-like peptides receptor 99D 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus granulosus adam 17 protease 0.0199 0.1183 0.1101
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Brugia malayi RE15519p 0.0197 0.1167 0.1085
Echinococcus granulosus biogenic amine 5HT receptor 0.0197 0.1167 0.1085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Schistosoma mansoni amine GPCR 0.0197 0.1167 0.1028
Loa Loa (eye worm) hypothetical protein 0.038 0.2809 0.2809
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus granulosus g protein coupled receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) melatonin receptor type 1A 0.0197 0.1167 0.1167
Echinococcus multilocularis g protein coupled receptor 0.0197 0.1167 0.1085
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0078 0.0098 0.5
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus granulosus g-protein coupled receptor 0.0197 0.1167 0.1085
Schistosoma mansoni biogenic amine receptor 0.0197 0.1167 0.1028
Echinococcus granulosus hypothetical protein 0.0197 0.1167 0.1085
Echinococcus multilocularis fmrfamide receptor 0.0197 0.1167 0.1085
Onchocerca volvulus 0.0197 0.1167 0.0975
Echinococcus multilocularis G-protein coupled receptor, putative 0.0197 0.1167 0.1085
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0233 0.1488 0.1409
Brugia malayi neuropeptide F receptor 0.0197 0.1167 0.1085
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0197 0.1167 0.1028
Onchocerca volvulus 0.0197 0.1167 0.0975
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0197 0.1167 0.1085
Onchocerca volvulus 0.0197 0.1167 0.0975
Loa Loa (eye worm) hypothetical protein 0.0078 0.0098 0.0098
Schistosoma mansoni alpha-1 adrenergic receptor 0.0197 0.1167 0.1028
Giardia lamblia Ceramide glucosyltransferase 0.0536 0.4204 0.5
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0072 0.0046 0.5
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Mycobacterium ulcerans hydrolase 0.0078 0.0098 0.5
Brugia malayi hypothetical protein 0.0197 0.1167 0.1085
Brugia malayi G-protein coupled receptor 0.0197 0.1167 0.1085
Onchocerca volvulus 0.0197 0.1167 0.0975
Brugia malayi GnHR receptor homolog 0.0197 0.1167 0.1085
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0085 0.0164 0.0073
Echinococcus granulosus alpha 1A adrenergic receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Loa Loa (eye worm) matrixin family protein 0.0142 0.0673 0.0673
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Brugia malayi hypothetical protein 0.0197 0.1167 0.1085
Echinococcus multilocularis dro:myosuppressin receptor 0.0197 0.1167 0.1085
Echinococcus multilocularis neuropeptide receptor 0.0197 0.1167 0.1085
Echinococcus granulosus rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Echinococcus multilocularis somatostatin receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Brugia malayi follicle stimulating hormone receptor 0.0197 0.1167 0.1085
Echinococcus multilocularis neuropeptide Y receptor 0.0197 0.1167 0.1085
Echinococcus granulosus neuropeptide receptor 0.0197 0.1167 0.1085
Echinococcus granulosus dro:myosuppressin receptor 0.0197 0.1167 0.1085
Echinococcus granulosus rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Onchocerca volvulus Matrix metalloproteinase homolog 0.0142 0.0673 0.047
Onchocerca volvulus 0.0197 0.1167 0.0975
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0197 0.1167 0.1167
Echinococcus granulosus 7tm_1 domain containing protein 0.0197 0.1167 0.1085
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0197 0.1167 0.1085
Onchocerca volvulus 0.0197 0.1167 0.0975
Echinococcus multilocularis g protein coupled receptor 0.0197 0.1167 0.1085
Brugia malayi sulfakinin receptor protein 0.0197 0.1167 0.1085
Brugia malayi G protein-coupled receptor 0.0197 0.1167 0.1085
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0197 0.1167 0.1085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0197 0.1167 0.1028
Brugia malayi Hemopexin family protein 0.0091 0.0213 0.0122
Echinococcus multilocularis adam 17 protease 0.0181 0.1021 0.0938
Echinococcus granulosus rhodopsin orphan GPCR 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167
Schistosoma mansoni hypothetical protein 0.0197 0.1167 0.1028
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0197 0.1167 0.1085
Onchocerca volvulus 0.0197 0.1167 0.0975
Schistosoma mansoni growth hormone secretagogue receptor 0.0197 0.1167 0.1028
Echinococcus multilocularis fmrfamide receptor 0.0197 0.1167 0.1085
Loa Loa (eye worm) hypothetical protein 0.0197 0.1167 0.1167

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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