Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.009 | 0.0485 | 1 |
Entamoeba histolytica | P-glycoprotein-2, putative | 0.009 | 0.0485 | 0.5 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0949 | 0.9545 | 0.9545 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.009 | 0.0485 | 1 |
Onchocerca volvulus | 0.0991 | 0.9986 | 1 | |
Loa Loa (eye worm) | multidrug resistance protein 3 | 0.009 | 0.0485 | 0.0011 |
Trichomonas vaginalis | taga, putative | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.009 | 0.0485 | 1 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.009 | 0.0485 | 1 |
Trypanosoma brucei | fatty acid desaturase, putative | 0.0992 | 1 | 0.5 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.009 | 0.0485 | 1 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0949 | 0.9545 | 0.9545 |
Trichomonas vaginalis | abcb9, putative | 0.009 | 0.0485 | 1 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.009 | 0.0485 | 1 |
Entamoeba histolytica | P-glycoprotein-2 | 0.009 | 0.0485 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0431 | 0.4076 | 0.3977 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0485 | 0.0011 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.009 | 0.0485 | 1 |
Toxoplasma gondii | ATP-binding cassette transporter ABC.B1 | 0.009 | 0.0485 | 0.5 |
Entamoeba histolytica | P-glycoprotein 5, putative | 0.009 | 0.0485 | 0.5 |
Trichomonas vaginalis | ABC transporter, putative | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.009 | 0.0485 | 1 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | abcb9, putative | 0.009 | 0.0485 | 1 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.009 | 0.0485 | 1 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.009 | 0.0485 | 1 |
Leishmania major | p-glycoprotein | 0.009 | 0.0485 | 0.0485 |
Entamoeba histolytica | P-glyco protein 6, putative | 0.009 | 0.0485 | 0.5 |
Entamoeba histolytica | P-glycoprotein-1 | 0.009 | 0.0485 | 0.5 |
Loa Loa (eye worm) | FAT-3 protein | 0.0431 | 0.4076 | 0.3977 |
Mycobacterium tuberculosis | Probable transmembrane multidrug efflux pump | 0.009 | 0.0485 | 1 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.009 | 0.0485 | 1 |
Echinococcus multilocularis | ATP binding cassette sub family B | 0.0089 | 0.0474 | 0.9639 |
Trichomonas vaginalis | ABC transporter, half transporter, putative | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.009 | 0.0485 | 1 |
Onchocerca volvulus | 0.0991 | 0.9986 | 1 | |
Brugia malayi | Delta5 fatty acid desaturase | 0.0431 | 0.4076 | 0.397 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | ABC transporter, putative | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | ABC transporter, putative | 0.009 | 0.0485 | 1 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.009 | 0.0485 | 1 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | abcb9, putative | 0.009 | 0.0485 | 1 |
Schistosoma mansoni | fatty acid desaturase | 0.0432 | 0.409 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0044 | 0 | 0.5 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | ABC transporter, half transporter, putative | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.009 | 0.0485 | 1 |
Plasmodium vivax | stearoyl-CoA desaturase (acyl-CoA desaturase, faty acid desaturase), putative | 0.0948 | 0.9531 | 1 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.009 | 0.0485 | 1 |
Toxoplasma gondii | ABC transporter transmembrane region domain-containing protein | 0.009 | 0.0485 | 0.5 |
Chlamydia trachomatis | ABC transporter ATP binding protein/permease | 0.009 | 0.0485 | 0.5 |
Leishmania major | fatty-acid desaturase, putative | 0.0992 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0485 | 0.0011 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.009 | 0.0485 | 1 |
Onchocerca volvulus | 0.0432 | 0.409 | 0.3795 | |
Plasmodium falciparum | stearoyl-CoA desaturase | 0.0948 | 0.9531 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.009 | 0.0485 | 1 |
Entamoeba histolytica | P-glycoprotein-2 | 0.009 | 0.0485 | 0.5 |
Entamoeba histolytica | P-glycoprotein-5 | 0.009 | 0.0485 | 0.5 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.009 | 0.0485 | 1 |
Echinococcus granulosus | 5'partial|ATP binding cassette sub family B | 0.0089 | 0.0474 | 0.9639 |
Leishmania major | ATP-binding cassette protein subfamily B, member 2, putative | 0.009 | 0.0485 | 0.0485 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.009 | 0.0485 | 1 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.009 | 0.0485 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.009 | 0.0485 | 1 |
Leishmania major | delta-5 fatty acid desaturase | 0.0431 | 0.4076 | 0.4076 |
Loa Loa (eye worm) | ATP-binding cassette sub-family B member 2 | 0.009 | 0.0485 | 0.0011 |
Trichomonas vaginalis | ABC transporter, putative | 0.009 | 0.0485 | 1 |
Loa Loa (eye worm) | acyl-CoA desaturase | 0.0948 | 0.9531 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0388 | 0.3621 | 0.3475 |
Brugia malayi | acyl-CoA desaturase | 0.0948 | 0.9531 | 1 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.009 | 0.0485 | 1 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.009 | 0.0485 | 1 |
Trypanosoma cruzi | fatty acid desaturase, putative | 0.0992 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.