TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 414.306 | Formula: C17H17Cl2N3O3S
H donors: 1 H acceptors: 3 LogP: 2.87 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: NC(=O)C1CCN(CC1)C(=O)c1csc(n1)COc1ccc(cc1Cl)Cl
InChi: 1S/C17H17Cl2N3O3S/c18-11-1-2-14(12(19)7-11)25-8-15-21-13(9-26-15)17(24)22-5-3-10(4-6-22)16(20)23/h1-2,7,9-10H,3-6,8H2,(H2,20,23)
InChiKey: KWHJUUCZKIZAHC-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Mycobacterium ulcerans	esterase/lipase LipP	0.0077	0.0701	0.1091
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0035	0.0209	0.1203
Loa Loa (eye worm)	beta-lactamase	0.0077	0.0701	0.2254
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0135	0.1393	0.2245
Trichomonas vaginalis	esterase, putative	0.0077	0.0701	0.2193
Mycobacterium ulcerans	nitrate/nitrite response regulator protein NarL	0.0531	0.6046	1
Trypanosoma cruzi	PAB1-binding protein , putative	0.0026	0.0109	0.0953
Loa Loa (eye worm)	hypothetical protein	0.0077	0.0701	0.2254
Mycobacterium ulcerans	putative regulatory protein	0.0531	0.6046	1
Trichomonas vaginalis	glucosylceramidase, putative	0.0176	0.1868	0.6102
Echinococcus granulosus	phd:f box containing protein	0.0021	0.0048	0.0007
Echinococcus multilocularis	lysine specific demethylase 6a	0.0021	0.0048	0.0002
Trypanosoma brucei	inositol-1(or 4)-monophosphatase 1, putative	0.004	0.0266	0.3353
Toxoplasma gondii	PHD-finger domain-containing protein	0.0065	0.0566	0.3855
Loa Loa (eye worm)	MH2 domain-containing protein	0.0128	0.1303	0.4326
Mycobacterium ulcerans	hypothetical protein	0.0531	0.6046	1
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0035	0.0209	0.0826
Trichomonas vaginalis	glucosylceramidase, putative	0.0268	0.2951	0.973
Trichomonas vaginalis	conserved hypothetical protein	0.0042	0.0293	0.0825
Mycobacterium ulcerans	hypothetical protein	0.0077	0.0701	0.1091
Brugia malayi	PHD-finger family protein	0.0065	0.0566	0.1917
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0293	0.0848
Onchocerca volvulus	Alhambra homolog	0.0065	0.0566	0.1333
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0097	0.0945	0.3978
Mycobacterium tuberculosis	Probable hydrolase	0.0077	0.0701	0.1091
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0077	0.0701	0.0658
Trichomonas vaginalis	chromobox protein, putative	0.0045	0.033	0.095
Trypanosoma cruzi	JmjC domain, hydroxylase, putative	0.0021	0.0048	0.0025
Onchocerca volvulus		0.0077	0.0701	0.1809
Schistosoma mansoni	ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related	0.0021	0.0048	0.0008
Schistosoma mansoni	chromobox protein	0.0075	0.0678	0.3216
Brugia malayi	MH2 domain containing protein	0.0128	0.1303	0.4415
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0051	0.0016
Mycobacterium tuberculosis	Probable lipase LipD	0.0077	0.0701	0.1091
Trypanosoma cruzi	JmjC domain, hydroxylase, putative	0.0021	0.0048	0.0025
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0048	0.0006
Trypanosoma cruzi	PAB1-binding protein , putative	0.0026	0.0109	0.0953
Loa Loa (eye worm)	heterochromatin protein 1	0.0075	0.0678	0.2173
Plasmodium falciparum	conserved Plasmodium membrane protein, unknown function	0.0021	0.0051	0.0092
Loa Loa (eye worm)	jmjC domain-containing protein	0.0134	0.1379	0.4589
Echinococcus granulosus	peregrin	0.0065	0.0566	0.2299
Loa Loa (eye worm)	jmjC domain-containing protein	0.0021	0.0048	0.0006
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0077	0.0701	0.2376
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0135	0.1393	0.2245
Echinococcus granulosus	chromobox protein 1	0.0075	0.0678	0.2796
Mycobacterium leprae	conserved hypothetical protein	0.0077	0.0701	0.083
Onchocerca volvulus		0.0077	0.0701	0.1809
Trichomonas vaginalis	glucosylceramidase, putative	0.0176	0.1868	0.6102
Brugia malayi	Pre-SET motif family protein	0.0241	0.264	0.8944
Brugia malayi	follicle stimulating hormone receptor	0.0248	0.2714	0.9198
Brugia malayi	beta-lactamase	0.0077	0.0701	0.2376
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0079	0.0727	0.3465
Trypanosoma cruzi	hypothetical protein, conserved	0.0077	0.0701	1
Plasmodium falciparum	ataxin-2 like protein, putative	0.0026	0.0109	0.1202
Toxoplasma gondii	aldehyde dehydrogenase	0.0135	0.1393	1
Leishmania major	hypothetical protein, conserved	0.0021	0.0048	0.0012
Plasmodium falciparum	phd finger protein, putative	0.0065	0.0566	1
Trichomonas vaginalis	glucosylceramidase, putative	0.0268	0.2951	0.973
Echinococcus granulosus	jumonji domain containing 1A	0.0021	0.0048	0.0007
Brugia malayi	O-Glycosyl hydrolase family 30 protein	0.0268	0.2951	1
Mycobacterium tuberculosis	Probable esterase/lipase LipP	0.0077	0.0701	0.1091
Plasmodium falciparum	ataxin-2 like protein, putative	0.0026	0.0109	0.1202
Trichomonas vaginalis	glucosylceramidase, putative	0.0176	0.1868	0.6102
Mycobacterium tuberculosis	Inositol-1-monophosphatase SuhB	0.0035	0.0217	0.0285
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.0135	0.1393	0.1353
Schistosoma mansoni	phd/f-box containing protein	0.0021	0.0048	0.0008
Toxoplasma gondii	WD domain, G-beta repeat-containing protein	0.0021	0.0051	0.0035
Loa Loa (eye worm)	hypothetical protein	0.0077	0.0701	0.2254
Schistosoma mansoni	protein phosphatase 2C	0.0021	0.0048	0.0008
Mycobacterium leprae	PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN	0.0531	0.6046	1
Brugia malayi	Pre-SET motif family protein	0.0035	0.0209	0.0707
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0209	0.0558
Mycobacterium leprae	Probable lipase LipE	0.0077	0.0701	0.083
Onchocerca volvulus	Glucosylceramidase homolog	0.0176	0.1868	0.591
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0097	0.0945	0.3201
Trichomonas vaginalis	chromobox protein, putative	0.0045	0.033	0.095
Loa Loa (eye worm)	transcription factor SMAD2	0.0128	0.1303	0.4326
Mycobacterium tuberculosis	Possible transcriptional regulatory protein	0.0531	0.6046	1
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0035	0.0209	0.0163
Mycobacterium tuberculosis	Possible conserved lipoprotein LpqK	0.0077	0.0701	0.1091
Schistosoma mansoni	hypothetical protein	0.0188	0.2009	1
Plasmodium vivax	hypothetical protein, conserved	0.0021	0.0051	0.0073
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0097	0.0945	0.4576
Brugia malayi	jmjC domain containing protein	0.0021	0.0048	0.0163
Schistosoma mansoni	inositol monophosphatase	0.004	0.0266	0.1118
Trichomonas vaginalis	penicillin-binding protein, putative	0.0077	0.0701	0.2193
Brugia malayi	jmjC domain containing protein	0.0021	0.0048	0.0163
Mycobacterium tuberculosis	Probable transcriptional regulatory protein (probably LuxR/UhpA-family)	0.0531	0.6046	1
Loa Loa (eye worm)	O-glycosyl hydrolase family 30 protein	0.0268	0.2951	1
Mycobacterium tuberculosis	Probable esterase LipL	0.0077	0.0701	0.1091
Onchocerca volvulus	Heterochromatin protein 1 homolog	0.0042	0.0293	0.0373
Schistosoma mansoni	aldehyde dehydrogenase	0.0135	0.1393	0.6862
Echinococcus multilocularis	chromobox protein 1	0.0075	0.0678	0.0634
Trypanosoma brucei	PHD-zinc-finger like domain containing protein, putative	0.0021	0.0051	0.0073
Brugia malayi	jmjC domain containing protein	0.0021	0.0048	0.0163
Trichomonas vaginalis	glucosylceramidase, putative	0.0268	0.2951	0.973
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0248	0.2714	0.9185
Plasmodium vivax	ataxin-2 like protein, putative	0.0026	0.0109	0.0953
Echinococcus granulosus	jumonji domain containing protein	0.009	0.0865	0.3625
Trichomonas vaginalis	conserved hypothetical protein	0.0042	0.0293	0.0825
Echinococcus granulosus	inositol monophosphatase 1	0.004	0.0266	0.0972
Mycobacterium tuberculosis	Probable lipase LipE	0.0077	0.0701	0.1091
Echinococcus multilocularis	JmjC domain containing protein 4	0.0021	0.0048	0.0002
Plasmodium vivax	JmjC domain containing protein	0.0021	0.0048	0.0025
Echinococcus multilocularis	chromobox protein 1	0.0075	0.0678	0.0634
Trichomonas vaginalis	myo inositol monophosphatase, putative	0.004	0.0266	0.0735
Mycobacterium ulcerans	lipase LipD	0.0077	0.0701	0.1091
Loa Loa (eye worm)	jmjC domain-containing protein	0.0021	0.0048	0.0006
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0079	0.0727	0.3465
Mycobacterium ulcerans	beta-lactamase	0.0077	0.0701	0.1091
Onchocerca volvulus		0.0077	0.0701	0.1809
Brugia malayi	beta-lactamase family protein	0.0077	0.0701	0.2376
Echinococcus multilocularis	inositol monophosphatase 1	0.004	0.0266	0.0221
Brugia malayi	chromobox protein homolog 3	0.0042	0.0293	0.0992
Mycobacterium tuberculosis	Conserved protein	0.0077	0.0701	0.1091
Brugia malayi	Inositol-1	0.004	0.0266	0.0902
Schistosoma mansoni	chromobox protein	0.0075	0.0678	0.3216
Trichomonas vaginalis	chromobox protein, putative	0.0075	0.0678	0.2115
Mycobacterium tuberculosis	Possible two component transcriptional regulatory protein (probably LuxR-family)	0.0531	0.6046	1
Trypanosoma cruzi	hypothetical protein, conserved	0.0077	0.0701	1
Mycobacterium ulcerans	extragenic suppressor protein SuhB	0.004	0.0266	0.0366
Trichomonas vaginalis	glucosylceramidase, putative	0.0268	0.2951	0.973
Loa Loa (eye worm)	jmjC domain-containing protein	0.0021	0.0048	0.0006
Echinococcus multilocularis	jumonji domain containing protein	0.009	0.0865	0.0822
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0213	0.2304	1
Trypanosoma cruzi	myo-inositol-1(or 4)-monophosphatase 1, putative	0.004	0.0266	0.3353
Echinococcus multilocularis	PHD finger protein rhinoceros	0.0065	0.0566	0.0522
Loa Loa (eye worm)	hypothetical protein	0.0077	0.0701	0.2254
Echinococcus multilocularis	lysine specific demethylase 5A	0.0079	0.0727	0.0683
Trichomonas vaginalis	D-aminoacylase, putative	0.0077	0.0701	0.2193
Toxoplasma gondii	ABC1 family protein	0.0077	0.0701	0.4862
Wolbachia endosymbiont of Brugia malayi	fructose-1,6-bisphosphatase	0.004	0.0266	1
Echinococcus granulosus	chromobox protein 1	0.0075	0.0678	0.2796
Plasmodium vivax	hypothetical protein, conserved	0.0077	0.0701	1
Schistosoma mansoni	hypothetical protein	0.0021	0.0051	0.0024
Mycobacterium tuberculosis	Probable transcriptional regulatory protein	0.0531	0.6046	1
Toxoplasma gondii	inositol(myo)-1(or 4)-monophosphatase 2, putative	0.004	0.0266	0.163
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.0135	0.1393	0.5964
Trypanosoma cruzi	myo-inositol-1(or 4)-monophosphatase 1, putative	0.004	0.0266	0.3353
Loa Loa (eye worm)	inositol-1	0.004	0.0266	0.0756
Echinococcus granulosus	geminin	0.0188	0.2009	0.8692
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0109	0.0215
Toxoplasma gondii	histone lysine demethylase JMJD6a	0.0021	0.0048	0.0012
Leishmania major	hypothetical protein, conserved	0.0026	0.0109	0.0463
Trichomonas vaginalis	set domain proteins, putative	0.0275	0.3032	1
Trichomonas vaginalis	glucosylceramidase, putative	0.0176	0.1868	0.6102
Brugia malayi	Heterochromatin protein 1	0.0075	0.0678	0.2297
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.0135	0.1393	1
Brugia malayi	hypothetical protein	0.0026	0.0109	0.0369
Brugia malayi	jmjC domain containing protein	0.0021	0.0048	0.0163
Echinococcus granulosus	lysine specific demethylase 6a	0.0021	0.0048	0.0007
Trypanosoma brucei	hypothetical protein, conserved	0.0077	0.0701	1
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0035	0.0209	0.0826
Echinococcus granulosus	JmjC domain containing protein 4	0.0021	0.0048	0.0007
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0097	0.0945	0.0902
Trichomonas vaginalis	glucosylceramidase, putative	0.0176	0.1868	0.6102
Loa Loa (eye worm)	hypothetical protein	0.0077	0.0701	0.2254
Trichomonas vaginalis	glucosylceramidase, putative	0.0185	0.1979	0.6475
Trypanosoma brucei	PAB1-binding protein , putative	0.0026	0.0109	0.0953
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0135	0.1393	0.2245
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0077	0.0701	0.3336
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0077	0.0701	0.2254
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0077	0.0701	0.3336
Loa Loa (eye worm)	jmjC domain-containing protein	0.0079	0.0727	0.2341
Brugia malayi	jmjC domain containing protein	0.0213	0.2304	0.7809
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0077	0.0701	0.1091
Onchocerca volvulus		0.0275	0.3032	1
Trichomonas vaginalis	penicillin-binding protein, putative	0.0077	0.0701	0.2193
Echinococcus granulosus	lysine specific demethylase 5A	0.0079	0.0727	0.3012
Brugia malayi	AF-10 protein	0.0021	0.0051	0.0174
Trypanosoma brucei	PHD-zinc-finger like domain containing protein, putative	0.0021	0.0051	0.0073
Schistosoma mansoni	phosphatidylserine receptor	0.0021	0.0048	0.0008
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0097	0.0945	0.3092
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0035	0.0209	0.0163
Brugia malayi	jmjC domain containing protein	0.0079	0.0727	0.2462
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0097	0.0945	0.3978
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0035	0.0209	0.0826
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0097	0.0945	0.4576
Plasmodium falciparum	JmjC domain-containing protein, putative	0.0021	0.0048	0.0032
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0048	0.0006
Brugia malayi	exodeoxyribonuclease III family protein	0.0021	0.0047	0.0158
Brugia malayi	beta-lactamase family protein	0.0077	0.0701	0.2376
Brugia malayi	Bromodomain containing protein	0.0065	0.0566	0.1917
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0097	0.0945	0.0902
Mycobacterium tuberculosis	Probable transcriptional regulatory protein (LuxR-family)	0.0531	0.6046	1
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0489	0.555	0.9173
Echinococcus granulosus	PHD finger protein rhinoceros	0.0065	0.0566	0.2299
Trichomonas vaginalis	myo inositol monophosphatase, putative	0.004	0.0266	0.0735
Onchocerca volvulus	Heterochromatin protein 1 homolog	0.0045	0.033	0.0504
Plasmodium vivax	SET domain protein, putative	0.0035	0.0209	0.2475
Toxoplasma gondii	LsmAD domain-containing protein	0.0026	0.0109	0.0463
Schistosoma mansoni	jumonji domain containing protein	0.0169	0.179	0.8884
Loa Loa (eye worm)	hypothetical protein	0.0077	0.0701	0.2254
Loa Loa (eye worm)	PHD-finger family protein	0.0065	0.0566	0.1788
Trichomonas vaginalis	D-aminoacylase, putative	0.0077	0.0701	0.2193
Schistosoma mansoni	hypothetical protein	0.0188	0.2009	1
Echinococcus multilocularis	jumonji domain containing 1A	0.0021	0.0048	0.0002
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0213	0.2304	0.2268
Echinococcus granulosus	Jumonji AT rich interactive domain 1B	0.0021	0.0048	0.0007
Mycobacterium ulcerans	two component transcriptional regulator	0.0531	0.6046	1
Schistosoma mansoni	inositol monophosphatase	0.004	0.0266	0.1118
Schistosoma mansoni	hypothetical protein	0.0065	0.0566	0.2645
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0021	0.0047	0.5
Trichomonas vaginalis	glucosylceramidase, putative	0.0185	0.1979	0.6475
Echinococcus multilocularis	phd:f box containing protein	0.0021	0.0048	0.0002
Onchocerca volvulus		0.0047	0.0352	0.0581
Leishmania major	hypothetical protein, conserved	0.0077	0.0701	0.4862
Trichomonas vaginalis	glucosylceramidase, putative	0.0176	0.1868	0.6102
Echinococcus multilocularis	Jumonji, AT rich interactive domain 1B	0.0021	0.0048	0.0002
Loa Loa (eye worm)	hypothetical protein	0.0065	0.0566	0.1788
Brugia malayi	F/Y-rich N-terminus family protein	0.0023	0.0066	0.0225
Schistosoma mansoni	jumonji domain containing protein	0.0021	0.0048	0.0008
Plasmodium vivax	hypothetical protein, conserved	0.0065	0.0566	0.793
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0033	0.0194	0.0651
Echinococcus multilocularis	peregrin	0.0065	0.0566	0.0522
Toxoplasma gondii	PHD-finger domain-containing protein	0.0021	0.0051	0.0035
Echinococcus multilocularis	geminin	0.0188	0.2009	0.1972
Trypanosoma brucei	JmjC domain, hydroxylase, putative	0.0021	0.0048	0.0025
Toxoplasma gondii	histone lysine demethylase JMJC1/KDM5D/JARID1D	0.0021	0.0048	0.0012
Toxoplasma gondii	PHD-finger domain-containing protein	0.0065	0.0566	0.3855
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0047	0.0352	0.1556
Echinococcus granulosus	beta LACTamase domain containing family member	0.0077	0.0701	0.29
Trichomonas vaginalis	chromobox protein, putative	0.0075	0.0678	0.2115
Mycobacterium tuberculosis	Probable conserved lipoprotein	0.0077	0.0701	0.1091
Echinococcus granulosus	histone lysine methyltransferase setb	0.0035	0.0209	0.0718
Mycobacterium tuberculosis	Conserved protein	0.0077	0.0701	0.1091
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0097	0.0945	0.4576
Loa Loa (eye worm)	hypothetical protein	0.0111	0.1112	0.3667
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0023	0.0066	0.0101
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0241	0.264	0.8927
Trichomonas vaginalis	glucosylceramidase, putative	0.0268	0.2951	0.973
Trichomonas vaginalis	conserved hypothetical protein	0.003	0.0149	0.0344
Trichomonas vaginalis	conserved hypothetical protein	0.003	0.0149	0.0344
Leishmania major	myo-inositol-1(or 4)-monophosphatase 1, putative	0.004	0.0266	0.163
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0187	0.0482
Trichomonas vaginalis	D-aminoacylase, putative	0.0077	0.0701	0.2193
Schistosoma mansoni	aldehyde dehydrogenase	0.0135	0.1393	0.6862
Brugia malayi	PHD-finger family protein	0.0021	0.0051	0.0174
Entamoeba histolytica	myo-inositol monophosphatase, putative	0.004	0.0266	1
Loa Loa (eye worm)	hypothetical protein	0.0077	0.0701	0.2254
Trichomonas vaginalis	glucosylceramidase, putative	0.0176	0.1868	0.6102
Schistosoma mansoni	bromodomain-containing nuclear protein 1 brd1	0.0065	0.0566	0.2645
Mycobacterium tuberculosis	Conserved protein	0.0077	0.0701	0.1091
Giardia lamblia	PHD finger protein 15	0.0065	0.0566	1
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.0135	0.1393	0.2245
Trichomonas vaginalis	inositol monophosphatase, putative	0.004	0.0266	0.0735
Mycobacterium ulcerans	two component transcriptional regulatory protein DevR	0.0531	0.6046	1
Mycobacterium tuberculosis	Possible nitrate/nitrite response transcriptional regulatory protein NarL	0.0531	0.6046	1
Trichomonas vaginalis	glucosylceramidase, putative	0.0268	0.2951	0.973

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by Saint Jude

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 885199