Detailed information for compound 889583

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 428.333 | Formula: C18H19Cl2N3O3S
  • H donors: 1 H acceptors: 3 LogP: 3.27 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNC(=O)C1CCN(CC1)C(=O)c1csc(n1)COc1ccc(cc1Cl)Cl
  • InChi: 1S/C18H19Cl2N3O3S/c1-21-17(24)11-4-6-23(7-5-11)18(25)14-10-27-16(22-14)9-26-15-3-2-12(19)8-13(15)20/h2-3,8,10-11H,4-7,9H2,1H3,(H,21,24)
  • InChiKey: BTWOJJAFVBYQTE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0021 0.0051 0.0024
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0266 0.163
Mycobacterium tuberculosis Probable transcriptional regulatory protein 0.0531 0.6046 1
Echinococcus granulosus geminin 0.0188 0.2009 0.8692
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0135 0.1393 0.5964
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0266 0.3353
Loa Loa (eye worm) inositol-1 0.004 0.0266 0.0756
Echinococcus granulosus chromobox protein 1 0.0075 0.0678 0.2796
Plasmodium vivax hypothetical protein, conserved 0.0077 0.0701 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0266 1
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0701 0.2193
Toxoplasma gondii ABC1 family protein 0.0077 0.0701 0.4862
Echinococcus multilocularis lysine specific demethylase 5A 0.0079 0.0727 0.0683
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0266 0.3353
Echinococcus multilocularis PHD finger protein rhinoceros 0.0065 0.0566 0.0522
Loa Loa (eye worm) hypothetical protein 0.0077 0.0701 0.2254
Loa Loa (eye worm) jmjC domain-containing protein 0.0021 0.0048 0.0006
Echinococcus multilocularis jumonji domain containing protein 0.009 0.0865 0.0822
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0213 0.2304 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0266 0.0366
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2951 0.973
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0701 1
Echinococcus granulosus lysine specific demethylase 6a 0.0021 0.0048 0.0007
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.0701 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0209 0.0826
Echinococcus granulosus JmjC domain containing protein 4 0.0021 0.0048 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0945 0.0902
Brugia malayi hypothetical protein 0.0026 0.0109 0.0369
Brugia malayi jmjC domain containing protein 0.0021 0.0048 0.0163
Leishmania major hypothetical protein, conserved 0.0026 0.0109 0.0463
Trichomonas vaginalis set domain proteins, putative 0.0275 0.3032 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0135 0.1393 1
Brugia malayi Heterochromatin protein 1 0.0075 0.0678 0.2297
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1868 0.6102
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0021 0.0048 0.0012
Loa Loa (eye worm) hypothetical protein 0.0026 0.0109 0.0215
Brugia malayi jmjC domain containing protein 0.0079 0.0727 0.2462
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0209 0.0163
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0945 0.3978
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0945 0.3092
Schistosoma mansoni phosphatidylserine receptor 0.0021 0.0048 0.0008
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0021 0.0051 0.0073
Onchocerca volvulus 0.0275 0.3032 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0701 0.2193
Echinococcus granulosus lysine specific demethylase 5A 0.0079 0.0727 0.3012
Brugia malayi AF-10 protein 0.0021 0.0051 0.0174
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0701 0.3336
Loa Loa (eye worm) jmjC domain-containing protein 0.0079 0.0727 0.2341
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0077 0.0701 0.1091
Brugia malayi jmjC domain containing protein 0.0213 0.2304 0.7809
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.1393 0.2245
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0701 0.3336
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0077 0.0701 0.2254
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1868 0.6102
Loa Loa (eye worm) hypothetical protein 0.0077 0.0701 0.2254
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1979 0.6475
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0109 0.0953
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0109 0.0463
Plasmodium vivax SET domain protein, putative 0.0035 0.0209 0.2475
Schistosoma mansoni jumonji domain containing protein 0.0169 0.179 0.8884
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.033 0.0504
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0266 0.0735
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0489 0.555 0.9173
Echinococcus granulosus PHD finger protein rhinoceros 0.0065 0.0566 0.2299
Brugia malayi Bromodomain containing protein 0.0065 0.0566 0.1917
Mycobacterium tuberculosis Probable transcriptional regulatory protein (LuxR-family) 0.0531 0.6046 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0945 0.0902
Brugia malayi beta-lactamase family protein 0.0077 0.0701 0.2376
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0047 0.0158
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0945 0.4576
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0209 0.0826
Plasmodium falciparum JmjC domain-containing protein, putative 0.0021 0.0048 0.0032
Echinococcus multilocularis phd:f box containing protein 0.0021 0.0048 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.1979 0.6475
Mycobacterium ulcerans two component transcriptional regulator 0.0531 0.6046 1
Schistosoma mansoni inositol monophosphatase 0.004 0.0266 0.1118
Schistosoma mansoni hypothetical protein 0.0065 0.0566 0.2645
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0047 0.5
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0048 0.0007
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0213 0.2304 0.2268
Echinococcus multilocularis jumonji domain containing 1A 0.0021 0.0048 0.0002
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0701 0.2193
Schistosoma mansoni hypothetical protein 0.0188 0.2009 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0701 0.2254
Loa Loa (eye worm) PHD-finger family protein 0.0065 0.0566 0.1788
Schistosoma mansoni jumonji domain containing protein 0.0021 0.0048 0.0008
Brugia malayi F/Y-rich N-terminus family protein 0.0023 0.0066 0.0225
Loa Loa (eye worm) hypothetical protein 0.0065 0.0566 0.1788
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0048 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1868 0.6102
Leishmania major hypothetical protein, conserved 0.0077 0.0701 0.4862
Onchocerca volvulus 0.0047 0.0352 0.0581
Loa Loa (eye worm) hypothetical protein 0.0111 0.1112 0.3667
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0066 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0149 0.0344
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0241 0.264 0.8927
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0149 0.0344
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2951 0.973
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0077 0.0701 0.1091
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0209 0.0718
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0945 0.4576
Mycobacterium tuberculosis Conserved protein 0.0077 0.0701 0.1091
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0047 0.0352 0.1556
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0678 0.2115
Echinococcus granulosus beta LACTamase domain containing family member 0.0077 0.0701 0.29
Toxoplasma gondii PHD-finger domain-containing protein 0.0065 0.0566 0.3855
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0021 0.0048 0.0012
Echinococcus multilocularis geminin 0.0188 0.2009 0.1972
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.0051 0.0035
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0021 0.0048 0.0025
Plasmodium vivax hypothetical protein, conserved 0.0065 0.0566 0.793
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0194 0.0651
Echinococcus multilocularis peregrin 0.0065 0.0566 0.0522
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2951 0.973
Mycobacterium tuberculosis Possible nitrate/nitrite response transcriptional regulatory protein NarL 0.0531 0.6046 1
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0266 0.0735
Mycobacterium ulcerans two component transcriptional regulatory protein DevR 0.0531 0.6046 1
Giardia lamblia PHD finger protein 15 0.0065 0.0566 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0135 0.1393 0.2245
Mycobacterium tuberculosis Conserved protein 0.0077 0.0701 0.1091
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0065 0.0566 0.2645
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1868 0.6102
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0266 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0701 0.2254
Loa Loa (eye worm) hypothetical protein 0.0033 0.0187 0.0482
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0266 0.163
Brugia malayi PHD-finger family protein 0.0021 0.0051 0.0174
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0701 0.2193
Schistosoma mansoni aldehyde dehydrogenase 0.0135 0.1393 0.6862
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2951 0.973
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0209 0.0826
Mycobacterium ulcerans hypothetical protein 0.0077 0.0701 0.1091
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0293 0.0825
Toxoplasma gondii PHD-finger domain-containing protein 0.0065 0.0566 0.3855
Mycobacterium ulcerans hypothetical protein 0.0531 0.6046 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0128 0.1303 0.4326
Echinococcus granulosus phd:f box containing protein 0.0021 0.0048 0.0007
Echinococcus multilocularis lysine specific demethylase 6a 0.0021 0.0048 0.0002
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0266 0.3353
Mycobacterium ulcerans putative regulatory protein 0.0531 0.6046 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0701 0.2254
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1868 0.6102
Trichomonas vaginalis esterase, putative 0.0077 0.0701 0.2193
Mycobacterium ulcerans nitrate/nitrite response regulator protein NarL 0.0531 0.6046 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.1393 0.2245
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0109 0.0953
Mycobacterium ulcerans esterase/lipase LipP 0.0077 0.0701 0.1091
Loa Loa (eye worm) beta-lactamase 0.0077 0.0701 0.2254
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0209 0.1203
Loa Loa (eye worm) hypothetical protein 0.0021 0.0051 0.0016
Mycobacterium tuberculosis Probable lipase LipD 0.0077 0.0701 0.1091
Schistosoma mansoni chromobox protein 0.0075 0.0678 0.3216
Brugia malayi MH2 domain containing protein 0.0128 0.1303 0.4415
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0021 0.0048 0.0025
Trichomonas vaginalis chromobox protein, putative 0.0045 0.033 0.095
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0021 0.0048 0.0008
Onchocerca volvulus 0.0077 0.0701 0.1809
Echinococcus multilocularis beta LACTamase domain containing family member 0.0077 0.0701 0.0658
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0945 0.3978
Mycobacterium tuberculosis Probable hydrolase 0.0077 0.0701 0.1091
Onchocerca volvulus Alhambra homolog 0.0065 0.0566 0.1333
Brugia malayi PHD-finger family protein 0.0065 0.0566 0.1917
Loa Loa (eye worm) hypothetical protein 0.0042 0.0293 0.0848
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0077 0.0701 0.2376
Mycobacterium ulcerans aldehyde dehydrogenase 0.0135 0.1393 0.2245
Echinococcus granulosus chromobox protein 1 0.0075 0.0678 0.2796
Mycobacterium leprae conserved hypothetical protein 0.0077 0.0701 0.083
Loa Loa (eye worm) jmjC domain-containing protein 0.0134 0.1379 0.4589
Echinococcus granulosus peregrin 0.0065 0.0566 0.2299
Loa Loa (eye worm) jmjC domain-containing protein 0.0021 0.0048 0.0006
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0109 0.0953
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0021 0.0051 0.0092
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0678 0.2173
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0021 0.0048 0.0025
Loa Loa (eye worm) hypothetical protein 0.0021 0.0048 0.0006
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0135 0.1393 0.1353
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0021 0.0051 0.0035
Loa Loa (eye worm) hypothetical protein 0.0077 0.0701 0.2254
Schistosoma mansoni phd/f-box containing protein 0.0021 0.0048 0.0008
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0109 0.1202
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0217 0.0285
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1868 0.6102
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0077 0.0701 0.1091
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0268 0.2951 1
Echinococcus granulosus jumonji domain containing 1A 0.0021 0.0048 0.0007
Plasmodium falciparum phd finger protein, putative 0.0065 0.0566 1
Leishmania major hypothetical protein, conserved 0.0021 0.0048 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2951 0.973
Schistosoma mansoni jumonji/arid domain-containing protein 0.0079 0.0727 0.3465
Toxoplasma gondii aldehyde dehydrogenase 0.0135 0.1393 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0109 0.1202
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0701 1
Brugia malayi beta-lactamase 0.0077 0.0701 0.2376
Trichomonas vaginalis glucosylceramidase, putative 0.0176 0.1868 0.6102
Onchocerca volvulus 0.0077 0.0701 0.1809
Brugia malayi follicle stimulating hormone receptor 0.0248 0.2714 0.9198
Brugia malayi Pre-SET motif family protein 0.0241 0.264 0.8944
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0945 0.3201
Trichomonas vaginalis chromobox protein, putative 0.0045 0.033 0.095
Loa Loa (eye worm) transcription factor SMAD2 0.0128 0.1303 0.4326
Onchocerca volvulus Glucosylceramidase homolog 0.0176 0.1868 0.591
Mycobacterium leprae Probable lipase LipE 0.0077 0.0701 0.083
Loa Loa (eye worm) hypothetical protein 0.0035 0.0209 0.0558
Brugia malayi Pre-SET motif family protein 0.0035 0.0209 0.0707
Mycobacterium leprae PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN 0.0531 0.6046 1
Schistosoma mansoni protein phosphatase 2C 0.0021 0.0048 0.0008
Mycobacterium tuberculosis Probable esterase LipL 0.0077 0.0701 0.1091
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0293 0.0373
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0701 0.2193
Brugia malayi jmjC domain containing protein 0.0021 0.0048 0.0163
Mycobacterium tuberculosis Probable transcriptional regulatory protein (probably LuxR/UhpA-family) 0.0531 0.6046 1
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0268 0.2951 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0945 0.4576
Schistosoma mansoni inositol monophosphatase 0.004 0.0266 0.1118
Brugia malayi jmjC domain containing protein 0.0021 0.0048 0.0163
Schistosoma mansoni hypothetical protein 0.0188 0.2009 1
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0051 0.0073
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0209 0.0163
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0077 0.0701 0.1091
Mycobacterium tuberculosis Possible transcriptional regulatory protein 0.0531 0.6046 1
Echinococcus multilocularis JmjC domain containing protein 4 0.0021 0.0048 0.0002
Echinococcus granulosus jumonji domain containing protein 0.009 0.0865 0.3625
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0293 0.0825
Mycobacterium tuberculosis Probable lipase LipE 0.0077 0.0701 0.1091
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0266 0.0972
Trichomonas vaginalis glucosylceramidase, putative 0.0268 0.2951 0.973
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0248 0.2714 0.9185
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0109 0.0953
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0021 0.0051 0.0073
Brugia malayi jmjC domain containing protein 0.0021 0.0048 0.0163
Echinococcus multilocularis chromobox protein 1 0.0075 0.0678 0.0634
Schistosoma mansoni aldehyde dehydrogenase 0.0135 0.1393 0.6862
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0678 0.2115
Mycobacterium tuberculosis Possible two component transcriptional regulatory protein (probably LuxR-family) 0.0531 0.6046 1
Brugia malayi Inositol-1 0.004 0.0266 0.0902
Schistosoma mansoni chromobox protein 0.0075 0.0678 0.3216
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0266 0.0221
Brugia malayi chromobox protein homolog 3 0.0042 0.0293 0.0992
Mycobacterium tuberculosis Conserved protein 0.0077 0.0701 0.1091
Schistosoma mansoni jumonji/arid domain-containing protein 0.0079 0.0727 0.3465
Mycobacterium ulcerans beta-lactamase 0.0077 0.0701 0.1091
Onchocerca volvulus 0.0077 0.0701 0.1809
Brugia malayi beta-lactamase family protein 0.0077 0.0701 0.2376
Loa Loa (eye worm) jmjC domain-containing protein 0.0021 0.0048 0.0006
Mycobacterium ulcerans lipase LipD 0.0077 0.0701 0.1091
Echinococcus multilocularis chromobox protein 1 0.0075 0.0678 0.0634
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0266 0.0735
Plasmodium vivax JmjC domain containing protein 0.0021 0.0048 0.0025

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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