Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cathepsin b | 0.2388 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.117 | 0.3976 | 1 |
Leishmania major | cathepsin L-like protease | 0.117 | 0.3976 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.117 | 0.3976 | 0.3976 |
Plasmodium vivax | vivapain-3 | 0.0634 | 0.1331 | 0.3347 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2388 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.117 | 0.3976 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0805 | 0.2173 | 0.2173 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.117 | 0.3976 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0925 | 0.2766 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0805 | 0.2173 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.117 | 0.3976 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.117 | 0.3976 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.117 | 0.3976 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Leishmania major | cathepsin L-like protease | 0.117 | 0.3976 | 1 |
Onchocerca volvulus | 0.117 | 0.3976 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0634 | 0.1331 | 0.1331 |
Onchocerca volvulus | 0.117 | 0.3976 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.117 | 0.3976 | 0.3052 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.117 | 0.3976 | 0.3976 |
Loa Loa (eye worm) | cathepsin B | 0.0925 | 0.2766 | 0.2766 |
Entamoeba histolytica | cysteine proteinase, putative | 0.117 | 0.3976 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.117 | 0.3976 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.117 | 0.3976 | 0.3976 |
Loa Loa (eye worm) | hypothetical protein | 0.2388 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.2388 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0925 | 0.2766 | 0.2766 |
Onchocerca volvulus | Cathepsin F homolog | 0.117 | 0.3976 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.117 | 0.3976 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0805 | 0.2173 | 0.2173 |
Giardia lamblia | Cathepsin B precursor | 0.0925 | 0.2766 | 0.5 |
Brugia malayi | cathepsin L-like precursor | 0.0805 | 0.2173 | 0.2173 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.117 | 0.3976 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.117 | 0.3976 | 0.3052 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.117 | 0.3976 | 0.3976 |
Loa Loa (eye worm) | fibroinase | 0.117 | 0.3976 | 0.3976 |
Loa Loa (eye worm) | hypothetical protein | 0.0805 | 0.2173 | 0.2173 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0805 | 0.2173 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.117 | 0.3976 | 0.3976 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0634 | 0.1331 | 0.1331 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0925 | 0.2766 | 0.2766 |
Brugia malayi | Cathepsin L-like precursor | 0.117 | 0.3976 | 0.3976 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0634 | 0.1331 | 0.1331 |
Brugia malayi | Cathepsin L-like precursor | 0.117 | 0.3976 | 0.3976 |
Plasmodium vivax | vivapain-2 | 0.117 | 0.3976 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0805 | 0.2173 | 0.2173 |
Echinococcus granulosus | cathepsin l1 | 0.0805 | 0.2173 | 0.0971 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0634 | 0.1331 | 0.1331 |
Onchocerca volvulus | Cathepsin L homolog | 0.117 | 0.3976 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0805 | 0.2173 | 0.2173 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.117 | 0.3976 | 0.3976 |
Toxoplasma gondii | cathepsin CPL | 0.117 | 0.3976 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.117 | 0.3976 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.117 | 0.3976 | 1 |
Leishmania major | cathepsin L-like protease | 0.117 | 0.3976 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.117 | 0.3976 | 0.3976 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0925 | 0.2766 | 0.5425 |
Onchocerca volvulus | 0.117 | 0.3976 | 1 | |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0925 | 0.2766 | 0.5425 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0805 | 0.2173 | 0.2173 |
Onchocerca volvulus | 0.117 | 0.3976 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.117 | 0.3976 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.2388 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0805 | 0.2173 | 0.2173 |
Echinococcus multilocularis | cysteine protease | 0.117 | 0.3976 | 0.3052 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.117 | 0.3976 | 0.3976 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.117 | 0.3976 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0634 | 0.1331 | 0.1331 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.117 | 0.3976 | 0.3052 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0634 | 0.1331 | 0.1331 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0805 | 0.2173 | 0.3182 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2388 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.117 | 0.3976 | 1 |
Echinococcus multilocularis | cathepsin b | 0.2388 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.117 | 0.3976 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.117 | 0.3976 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.117 | 0.3976 | 0.3976 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.117 | 0.3976 | 0.3052 |
Plasmodium vivax | unspecified product | 0.0634 | 0.1331 | 0.3347 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.117 | 0.3976 | 0.3052 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0805 | 0.2173 | 0.2173 |
Leishmania major | cathepsin L-like protease | 0.117 | 0.3976 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.117 | 0.3976 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.117 | 0.3976 | 0.3976 |
Loa Loa (eye worm) | hypothetical protein | 0.117 | 0.3976 | 0.3976 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0634 | 0.1331 | 0.1331 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Leishmania major | cathepsin L-like protease | 0.117 | 0.3976 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.117 | 0.3976 | 0.3052 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.117 | 0.3976 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.117 | 0.3976 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0634 | 0.1331 | 0.1331 |
Loa Loa (eye worm) | ctsf protein | 0.117 | 0.3976 | 0.3976 |
Brugia malayi | Papain family cysteine protease containing protein | 0.117 | 0.3976 | 0.3976 |
Giardia lamblia | Cathepsin B precursor | 0.0925 | 0.2766 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2388 | 1 | 1 |
Onchocerca volvulus | 0.117 | 0.3976 | 1 | |
Onchocerca volvulus | 0.117 | 0.3976 | 1 | |
Onchocerca volvulus | 0.117 | 0.3976 | 1 | |
Loa Loa (eye worm) | cysteine protease | 0.117 | 0.3976 | 0.3976 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.117 | 0.3976 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.117 | 0.3976 | 0.3052 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Plasmodium vivax | vivapain-1 | 0.0634 | 0.1331 | 0.3347 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0634 | 0.1331 | 0.1331 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.117 | 0.3976 | 0.3976 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.117 | 0.3976 | 0.3976 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.117 | 0.3976 | 0.3976 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0634 | 0.1331 | 0.1331 |
Echinococcus multilocularis | cysteine protease | 0.117 | 0.3976 | 0.3052 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Plasmodium vivax | vivapain-2 | 0.117 | 0.3976 | 1 |
Echinococcus granulosus | cathepsin b | 0.2388 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.2388 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.117 | 0.3976 | 1 |
Leishmania major | cathepsin L-like protease | 0.117 | 0.3976 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.