Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1202 | 0.454 | 0.3993 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1202 | 0.454 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0654 | 0.2382 | 0.4054 |
Echinococcus multilocularis | cysteine protease | 0.1202 | 0.454 | 0.3993 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0374 | 0.1279 | 0.1279 |
Onchocerca volvulus | 0.1202 | 0.454 | 1 | |
Echinococcus multilocularis | cysteine protease | 0.1202 | 0.454 | 0.3993 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.028 | 0.091 | 0.091 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2589 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0994 | 0.3721 | 0.7745 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0654 | 0.2382 | 0.1619 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1202 | 0.454 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.028 | 0.091 | 0.091 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1202 | 0.454 | 0.3993 |
Entamoeba histolytica | cysteine protease, putative | 0.0654 | 0.2382 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.028 | 0.091 | 0.091 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1202 | 0.454 | 0.3993 |
Entamoeba histolytica | cysteine protease, putative | 0.0654 | 0.2382 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0654 | 0.2382 | 0.4054 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1202 | 0.454 | 0.3993 |
Leishmania major | cathepsin L-like protease | 0.1202 | 0.454 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2589 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2589 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.091 | 0.091 |
Onchocerca volvulus | Cathepsin L homolog | 0.1202 | 0.454 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1202 | 0.454 | 0.454 |
Loa Loa (eye worm) | ctsf protein | 0.1202 | 0.454 | 0.454 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0828 | 0.3068 | 0.5946 |
Loa Loa (eye worm) | fibroinase | 0.1202 | 0.454 | 0.454 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1202 | 0.454 | 0.3993 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.028 | 0.091 | 0.091 |
Entamoeba histolytica | cysteine protease, putative | 0.0654 | 0.2382 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0654 | 0.2382 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0654 | 0.2382 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.091 | 0.091 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0654 | 0.2382 | 0.1619 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0654 | 0.2382 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.1202 | 0.454 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0374 | 0.1279 | 0.1279 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1202 | 0.454 | 0.3993 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.2589 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1202 | 0.454 | 1 |
Echinococcus multilocularis | cathepsin b | 0.2589 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0654 | 0.2382 | 0.4054 |
Echinococcus granulosus | cathepsin l1 | 0.0828 | 0.3068 | 0.2374 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.091 | 0.091 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0654 | 0.2382 | 0.1619 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0374 | 0.1279 | 0.0406 |
Onchocerca volvulus | Cathepsin L homolog | 0.1202 | 0.454 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0654 | 0.2382 | 0.1619 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1202 | 0.454 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1202 | 0.454 | 0.3993 |
Onchocerca volvulus | 0.1202 | 0.454 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0828 | 0.3068 | 0.5946 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.028 | 0.091 | 0.091 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0654 | 0.2382 | 0.1619 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.028 | 0.091 | 0.091 |
Leishmania major | cathepsin L-like protease | 0.1202 | 0.454 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1202 | 0.454 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0654 | 0.2382 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0374 | 0.1279 | 0.1279 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.091 | 0.091 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.028 | 0.091 | 0.091 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1202 | 0.454 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1202 | 0.454 | 0.454 |
Leishmania major | cathepsin L-like protease | 0.1202 | 0.454 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0828 | 0.3068 | 0.2374 |
Plasmodium vivax | vivapain-2 | 0.1202 | 0.454 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0654 | 0.2382 | 0.4054 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.028 | 0.091 | 0.091 |
Plasmodium vivax | vivapain-3 | 0.0654 | 0.2382 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0828 | 0.3068 | 0.2374 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1202 | 0.454 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1202 | 0.454 | 0.3993 |
Entamoeba histolytica | cysteine protease, putative | 0.0654 | 0.2382 | 0.4054 |
Plasmodium vivax | vivapain-1 | 0.0654 | 0.2382 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0828 | 0.3068 | 0.3068 |
Giardia lamblia | Cathepsin B precursor | 0.0994 | 0.3721 | 1 |
Plasmodium vivax | unspecified product | 0.0374 | 0.1279 | 0.1017 |
Brugia malayi | Papain family cysteine protease containing protein | 0.028 | 0.091 | 0.091 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1202 | 0.454 | 0.3993 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1202 | 0.454 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0795 | 0.2938 | 0.2231 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.1202 | 0.454 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0654 | 0.2382 | 0.4054 |
Loa Loa (eye worm) | cathepsin B | 0.0994 | 0.3721 | 0.3721 |
Entamoeba histolytica | cysteine protease, putative | 0.0654 | 0.2382 | 0.4054 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0654 | 0.2382 | 0.1619 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1202 | 0.454 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0654 | 0.2382 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0828 | 0.3068 | 0.3068 |
Brugia malayi | cathepsin L-like precursor | 0.0828 | 0.3068 | 0.3068 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1202 | 0.454 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0654 | 0.2382 | 0.4054 |
Brugia malayi | Papain family cysteine protease containing protein | 0.028 | 0.091 | 0.091 |
Onchocerca volvulus | 0.1202 | 0.454 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.1202 | 0.454 | 0.454 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.028 | 0.091 | 0.091 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0828 | 0.3068 | 0.3068 |
Brugia malayi | Cathepsin L-like precursor | 0.0374 | 0.1279 | 0.1279 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0994 | 0.3721 | 0.3093 |
Echinococcus granulosus | cysteine protease | 0.0654 | 0.2382 | 0.1619 |
Echinococcus granulosus | cathepsin b | 0.2589 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1202 | 0.454 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.1202 | 0.454 | 0.3993 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0654 | 0.2382 | 0.4054 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1202 | 0.454 | 0.454 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0828 | 0.3068 | 0.5946 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1202 | 0.454 | 1 |
Toxoplasma gondii | cathepsin B | 0.0994 | 0.3721 | 0.7745 |
Echinococcus multilocularis | cathepsin L | 0.0654 | 0.2382 | 0.1619 |
Entamoeba histolytica | cysteine protease, putative | 0.0654 | 0.2382 | 0.4054 |
Onchocerca volvulus | Cathepsin F homolog | 0.1202 | 0.454 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0994 | 0.3721 | 0.6208 |
Leishmania major | cathepsin L-like protease | 0.1202 | 0.454 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1202 | 0.454 | 0.3993 |
Loa Loa (eye worm) | hypothetical protein | 0.0374 | 0.1279 | 0.1279 |
Brugia malayi | Cathepsin L-like precursor | 0.1202 | 0.454 | 0.454 |
Loa Loa (eye worm) | hypothetical protein | 0.0374 | 0.1279 | 0.1279 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1202 | 0.454 | 0.454 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0654 | 0.2382 | 0.2382 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1202 | 0.454 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.1202 | 0.454 | 1 |
Echinococcus granulosus | cathepsin L | 0.0654 | 0.2382 | 0.1619 |
Onchocerca volvulus | 0.0828 | 0.3068 | 0.5946 | |
Onchocerca volvulus | 0.1202 | 0.454 | 1 | |
Plasmodium vivax | unspecified product | 0.0654 | 0.2382 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0654 | 0.2382 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.1202 | 0.454 | 0.454 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1202 | 0.454 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1202 | 0.454 | 0.454 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1202 | 0.454 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0828 | 0.3068 | 0.3068 |
Giardia lamblia | Cathepsin B precursor | 0.0994 | 0.3721 | 1 |
Onchocerca volvulus | 0.1202 | 0.454 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0654 | 0.2382 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.1202 | 0.454 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0828 | 0.3068 | 0.3068 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1202 | 0.454 | 0.3993 |
Loa Loa (eye worm) | hypothetical protein | 0.2589 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0654 | 0.2382 | 0.1619 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0654 | 0.2382 | 0.4054 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0654 | 0.2382 | 0.1619 |
Leishmania major | cathepsin L-like protease | 0.1202 | 0.454 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0654 | 0.2382 | 0.1619 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0374 | 0.1279 | 0.0406 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1202 | 0.454 | 0.454 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.091 | 0.091 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1202 | 0.454 | 1 |
Echinococcus multilocularis | cathepsin b | 0.2589 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0828 | 0.3068 | 0.3068 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.091 | 0.091 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1202 | 0.454 | 0.3993 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0994 | 0.3721 | 0.3093 |
Onchocerca volvulus | 0.1202 | 0.454 | 1 | |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0374 | 0.1279 | 0.1279 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.2589 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.2589 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1202 | 0.454 | 0.454 |
Leishmania major | cathepsin L-like protease | 0.1202 | 0.454 | 1 |
Brugia malayi | fibroinase precursor | 0.028 | 0.091 | 0.091 |
Schistosoma mansoni | cathepsin s | 0.0374 | 0.1279 | 0.0406 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Brugia malayi | cathepsin L precursor | 0.028 | 0.091 | 0.091 |
Giardia lamblia | Cathepsin B precursor | 0.0994 | 0.3721 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.1202 | 0.454 | 0.454 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1202 | 0.454 | 1 |
Plasmodium vivax | vivapain-2 | 0.1202 | 0.454 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1202 | 0.454 | 0.3993 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0654 | 0.2382 | 0.2382 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1202 | 0.454 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0654 | 0.2382 | 0.4054 |
Onchocerca volvulus | 0.1202 | 0.454 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.