Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | cathepsin B | 0.1218 | 0.3093 | 0.5842 |
Entamoeba histolytica | cysteine protease, putative | 0.0968 | 0.2146 | 0.4054 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0528 | 0.0485 | 0.0485 |
Entamoeba histolytica | cysteine protease, putative | 0.0968 | 0.2146 | 0.4054 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1802 | 0.5294 | 0.5294 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1802 | 0.5294 | 0.5294 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1802 | 0.5294 | 0.5294 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.1218 | 0.3093 | 0.3006 |
Plasmodium vivax | unspecified product | 0.0569 | 0.0639 | 0.1207 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.042 | 0.0077 | 0.0077 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1802 | 0.5294 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1802 | 0.5294 | 0.5294 |
Brugia malayi | Cathepsin L-like precursor | 0.1802 | 0.5294 | 0.5294 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0569 | 0.0639 | 0.0639 |
Entamoeba histolytica | cysteine protease, putative | 0.1802 | 0.5294 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1802 | 0.5294 | 0.5294 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0968 | 0.2146 | 0.2146 |
Onchocerca volvulus | Cathepsin F homolog | 0.1802 | 0.5294 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1802 | 0.5294 | 0.5294 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.1233 | 0.3148 | 0.3148 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0968 | 0.2146 | 0.2146 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0483 | 0.0318 | 0.0318 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0968 | 0.2146 | 0.2146 |
Loa Loa (eye worm) | hypothetical protein | 0.0569 | 0.0639 | 0.0639 |
Onchocerca volvulus | 0.1802 | 0.5294 | 1 | |
Entamoeba histolytica | cysteine proteinase 2 | 0.0968 | 0.2146 | 0.4054 |
Loa Loa (eye worm) | fibroinase | 0.1802 | 0.5294 | 0.5294 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1802 | 0.5294 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1802 | 0.5294 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0569 | 0.0639 | 0.0639 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3048 | 1 | 1 |
Onchocerca volvulus | 0.1802 | 0.5294 | 1 | |
Echinococcus multilocularis | cathepsin b | 0.3048 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1802 | 0.5294 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1218 | 0.3093 | 0.3093 |
Echinococcus granulosus | cathepsin L | 0.0968 | 0.2146 | 0.2146 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0968 | 0.2146 | 0.2146 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0968 | 0.2146 | 0.2146 |
Onchocerca volvulus | 0.1802 | 0.5294 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0968 | 0.2146 | 0.4054 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0968 | 0.2146 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0968 | 0.2146 | 0.2146 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.1218 | 0.3093 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3048 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1802 | 0.5294 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.1802 | 0.5294 | 0.5294 |
Plasmodium vivax | vivapain-3 | 0.0968 | 0.2146 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.1802 | 0.5294 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1802 | 0.5294 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3048 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1802 | 0.5294 | 0.5294 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0483 | 0.0318 | 0.0318 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.1802 | 0.5294 | 0.5294 |
Trypanosoma cruzi | cysteine protease, putative | 0.0968 | 0.2146 | 0.2146 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1802 | 0.5294 | 0.5294 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0968 | 0.2146 | 0.2146 |
Onchocerca volvulus | 0.1802 | 0.5294 | 1 | |
Echinococcus multilocularis | cysteine protease | 0.1802 | 0.5294 | 0.5294 |
Loa Loa (eye worm) | hypothetical protein | 0.1233 | 0.3148 | 0.3148 |
Entamoeba histolytica | cysteine protease, putative | 0.0968 | 0.2146 | 0.4054 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.3048 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1802 | 0.5294 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1802 | 0.5294 | 0.5294 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0569 | 0.0639 | 0.0639 |
Entamoeba histolytica | cysteine protease, putative | 0.0968 | 0.2146 | 0.4054 |
Echinococcus multilocularis | cysteine protease | 0.1802 | 0.5294 | 0.5294 |
Plasmodium vivax | unspecified product | 0.0968 | 0.2146 | 0.4054 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1802 | 0.5294 | 0.5294 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Echinococcus granulosus | cysteine protease | 0.0968 | 0.2146 | 0.2146 |
Onchocerca volvulus | 0.1802 | 0.5294 | 1 | |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0452 | 0.0198 | 0.0373 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1802 | 0.5294 | 0.5294 |
Schistosoma mansoni | cathepsin s | 0.0569 | 0.0639 | 0.0639 |
Brugia malayi | Cathepsin L-like precursor | 0.1233 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1802 | 0.5294 | 0.5294 |
Echinococcus granulosus | cathepsin b | 0.3048 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.3048 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1802 | 0.5294 | 1 |
Leishmania major | cathepsin L-like protease | 0.1802 | 0.5294 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0483 | 0.0318 | 0.0318 |
Giardia lamblia | Cathepsin B precursor | 0.1218 | 0.3093 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1233 | 0.3148 | 0.5946 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1802 | 0.5294 | 0.5294 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0569 | 0.0639 | 0.0639 |
Entamoeba histolytica | cysteine protease, putative | 0.0968 | 0.2146 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0968 | 0.2146 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.1802 | 0.5294 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0569 | 0.0639 | 0.0639 |
Onchocerca volvulus | 0.1802 | 0.5294 | 1 | |
Echinococcus granulosus | cathepsin b | 0.3048 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1802 | 0.5294 | 0.5294 |
Giardia lamblia | Cathepsin B precursor | 0.1218 | 0.3093 | 1 |
Leishmania major | cathepsin L-like protease | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0968 | 0.2146 | 0.4054 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3048 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0968 | 0.2146 | 0.4054 |
Plasmodium vivax | vivapain-2 | 0.1802 | 0.5294 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1233 | 0.3148 | 0.5946 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1218 | 0.3093 | 0.3093 |
Entamoeba histolytica | cysteine protease, putative | 0.0968 | 0.2146 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1802 | 0.5294 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0968 | 0.2146 | 0.4054 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0968 | 0.2146 | 0.2146 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Plasmodium vivax | vivapain-2 | 0.1802 | 0.5294 | 1 |
Leishmania major | cathepsin L-like protease | 0.1802 | 0.5294 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0968 | 0.2146 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1802 | 0.5294 | 0.5294 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1802 | 0.5294 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1802 | 0.5294 | 1 |
Onchocerca volvulus | 0.1233 | 0.3148 | 0.5946 | |
Entamoeba histolytica | cysteine protease, putative | 0.0968 | 0.2146 | 0.4054 |
Onchocerca volvulus | 0.1802 | 0.5294 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.1233 | 0.3148 | 0.3148 |
Brugia malayi | Cathepsin L-like precursor | 0.1802 | 0.5294 | 0.5294 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0528 | 0.0485 | 0.0485 |
Brugia malayi | Cathepsin L-like precursor | 0.0569 | 0.0639 | 0.0639 |
Brugia malayi | Cathepsin L-like precursor | 0.1802 | 0.5294 | 0.5294 |
Leishmania major | cathepsin L-like protease | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1233 | 0.3148 | 0.3148 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1802 | 0.5294 | 0.5294 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0968 | 0.2146 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.1802 | 0.5294 | 0.5294 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0968 | 0.2146 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.3048 | 1 | 1 |
Plasmodium vivax | vivapain-1 | 0.0968 | 0.2146 | 0.4054 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1802 | 0.5294 | 0.5294 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1802 | 0.5294 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0968 | 0.2146 | 0.4054 |
Loa Loa (eye worm) | cathepsin B | 0.1218 | 0.3093 | 0.3093 |
Loa Loa (eye worm) | cysteine protease | 0.1802 | 0.5294 | 0.5294 |
Entamoeba histolytica | cysteine protease, putative | 0.0968 | 0.2146 | 0.4054 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1802 | 0.5294 | 0.5294 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0483 | 0.0318 | 0.0318 |
Onchocerca volvulus | Cathepsin L homolog | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.1218 | 0.3093 | 0.5842 |
Echinococcus granulosus | cathepsin l1 | 0.1233 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0569 | 0.0639 | 0.0639 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0452 | 0.0198 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.1233 | 0.3148 | 0.3148 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1233 | 0.3148 | 0.5946 |
Toxoplasma gondii | cathepsin CPL | 0.1802 | 0.5294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.1233 | 0.3148 | 0.3148 |
Entamoeba histolytica | cysteine protease, putative | 0.0968 | 0.2146 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1802 | 0.5294 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0968 | 0.2146 | 0.2146 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0968 | 0.2146 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0968 | 0.2146 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.1802 | 0.5294 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1233 | 0.3148 | 0.3148 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0968 | 0.2146 | 0.2146 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1802 | 0.5294 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1802 | 0.5294 | 0.5294 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0569 | 0.0639 | 0.0639 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.1233 | 0.3148 | 0.3148 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1802 | 0.5294 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0968 | 0.2146 | 0.2146 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.