Detailed information for compound 899493

Basic information

Technical information
  • TDR Targets ID: 899493
  • Name: 3-phenyl-3-[(4-propan-2-ylphenyl)sulfonylamin o]propanoic acid
  • MW: 347.429 | Formula: C18H21NO4S
  • H donors: 2 H acceptors: 4 LogP: 3.04 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(c1ccc(cc1)S(=O)(=O)NC(c1ccccc1)CC(=O)O)C
  • InChi: 1S/C18H21NO4S/c1-13(2)14-8-10-16(11-9-14)24(22,23)19-17(12-18(20)21)15-6-4-3-5-7-15/h3-11,13,17,19H,12H2,1-2H3,(H,20,21)
  • InChiKey: DBSRXZMTMQLHQG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[(4-isopropylphenyl)sulfonylamino]-3-phenyl-propanoic acid
  • 3-[(4-isopropylphenyl)sulfonylamino]-3-phenylpropanoic acid
  • 3-[(4-isopropylphenyl)sulfonylamino]-3-phenyl-propionic acid
  • AQ-390/42132976

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus cathepsin l cysteine peptidase 0.0845 0.2549 0.2548
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0018 0.0039
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0027 0.0016 0.0046
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0046 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Onchocerca volvulus 0.003 0.0026 0.0076
Loa Loa (eye worm) steroid hormone receptor 0.0195 0.0536 0.0535
Loa Loa (eye worm) hypothetical protein 0.0232 0.0651 0.065
Echinococcus granulosus chromobox protein 1 0.0073 0.0159 0.0157
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Echinococcus multilocularis cysteine protease 0.0845 0.2549 0.2548
Echinococcus granulosus beta LACTamase domain containing family member 0.0062 0.0123 0.0122
Loa Loa (eye worm) hypothetical protein 0.0597 0.178 0.1779
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0232 0.0651 0.1837
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0042 0.0063 0.0162
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0044
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0176 0.0478 0.0477
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0232 0.0651 0.065
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0024 0.0006 0.0007
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0558 0.1658 0.1657
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0028 0.0018 0.0049
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0024
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0027 0.0016 0.0014
Treponema pallidum fructose-bisphosphate aldolase 0.0948 0.2867 1
Plasmodium falciparum serine repeat antigen 9 0.0232 0.0651 0.2542
Entamoeba histolytica hypothetical protein 0.0036 0.0044 0.014
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0119 0.0842
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0042 0.0063 0.0167
Onchocerca volvulus 0.0232 0.0651 0.2535
Plasmodium vivax thioredoxin reductase, putative 0.0078 0.0173 0.0664
Trypanosoma cruzi hypothetical protein, conserved 0.0062 0.0123 0.0123
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0491 0.1385
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.003 0.0025 0.0025
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0046 0.0074 0.0243
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0006 0.0016
Plasmodium vivax ataxin-2 like protein, putative 0.0043 0.0065 0.0239
Trichomonas vaginalis CAMK family protein kinase 0.0036 0.0043 0.012
Loa Loa (eye worm) hypothetical protein 0.0123 0.0313 0.0311
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0062 0.0123 0.0877
Brugia malayi chromobox protein homolog 3 0.0041 0.0059 0.0058
Schistosoma mansoni nuclear hormone receptor 0.0195 0.0536 0.0535
Brugia malayi CXXC zinc finger family protein 0.0097 0.0232 0.0231
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0028 0.0018 0.0039
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Trypanosoma cruzi cysteine protease, putative 0.0481 0.1421 0.1421
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0036 0.0042 0.0134
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0027 0.0015 0.0014
Schistosoma mansoni alpha glucosidase 0.0045 0.0071 0.007
Brugia malayi Latrophilin receptor protein 2 0.0176 0.0478 0.0477
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.024 0.0675 0.0674
Toxoplasma gondii PHD-finger domain-containing protein 0.0024 0.0006 0.0007
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0027 0.0016 0.0033
Plasmodium vivax unspecified product 0.0232 0.0651 0.2542
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0948 0.2867 1
Entamoeba histolytica cysteine proteinase, putative 0.0845 0.2549 0.8891
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0481 0.1421 0.1419
Toxoplasma gondii thioredoxin reductase 0.0078 0.0173 0.0478
Schistosoma mansoni lamin 0.0024 0.0006 0.0005
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1166 0.3542 0.3542
Onchocerca volvulus 0.0845 0.2549 1
Brugia malayi beta-NAC-like protein 0.0026 0.0013 0.0012
Brugia malayi mbt repeat family protein 0.008 0.0179 0.0178
Schistosoma mansoni tsg101-related 0.0044 0.0067 0.0066
Brugia malayi PHD-finger family protein 0.0073 0.0159 0.0158
Schistosoma mansoni loxhd1 0.003 0.0026 0.0024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Schistosoma mansoni tyrosine kinase 0.0591 0.1763 0.1762
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.009 0.0212 0.021
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0011
Onchocerca volvulus 0.0195 0.0536 0.2082
Schistosoma mansoni coup transcription factor 0.0195 0.0536 0.0535
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0232 0.0651 0.1824
Schistosoma mansoni Smad4 0.0027 0.0015 0.0014
Trypanosoma cruzi cysteine peptidase, putative 0.0481 0.1421 0.1421
Mycobacterium tuberculosis Probable oxidoreductase 0.0197 0.0543 0.3957
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0042 0.0063 0.0435
Schistosoma mansoni lipoxygenase 0.0131 0.0339 0.0338
Schistosoma mansoni hypothetical protein 0.0231 0.0649 0.0648
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0092 0.0217 0.0216
Plasmodium vivax vivapain-3 0.0481 0.1421 0.5565
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Mycobacterium tuberculosis Probable esterase LipL 0.0062 0.0123 0.0877
Brugia malayi latrophilin 2 splice variant baaae 0.0381 0.1112 0.1111
Plasmodium falciparum cysteine proteinase falcipain 1 0.0481 0.1421 0.5565
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0062 0.0123 0.0122
Echinococcus multilocularis polycomb protein SCMH1 0.008 0.0179 0.0178
Trichomonas vaginalis sucrase-isomaltase, putative 0.0045 0.0071 0.0199
Onchocerca volvulus 0.0845 0.2549 1
Loa Loa (eye worm) ctsf protein 0.0845 0.2549 0.2548
Giardia lamblia Cathepsin L precursor 0.0232 0.0651 0.1824
Giardia lamblia Cathepsin B precursor 0.0232 0.0651 0.1824
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0176 0.0478 0.0477
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0092 0.0258
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Echinococcus granulosus smad 0.0027 0.0015 0.0014
Schistosoma mansoni tyrosine kinase 0.0591 0.1763 0.1762
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0024 0.0006 0.0007
Echinococcus granulosus TGF beta signal transducer SmadC 0.0027 0.0015 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.0195 0.0536 0.0535
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.3252 1 1
Echinococcus granulosus histone acetyltransferase MYST2 0.0091 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0202 0.0556 0.0555
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0059 0.0208
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Brugia malayi F/Y-rich N-terminus family protein 0.0061 0.0122 0.012
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0323 0.0932 0.0931
Brugia malayi Intermediate filament tail domain containing protein 0.0024 0.0006 0.0005
Toxoplasma gondii cathepsin CPL 0.0845 0.2549 0.7193
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0092 0.0217 0.0216
Giardia lamblia Encystation-specific protease 0.0232 0.0651 0.1824
Brugia malayi Bromodomain containing protein 0.0096 0.023 0.0229
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Entamoeba histolytica hypothetical protein 0.0036 0.0044 0.014
Trichomonas vaginalis esterase, putative 0.0062 0.0123 0.0348
Trypanosoma brucei trypanothione reductase 0.0078 0.0173 0.0478
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0018 0.0018
Plasmodium falciparum LCCL domain-containing protein 0.003 0.0026 0.0085
Echinococcus multilocularis neuropeptide receptor A26 0.0917 0.2771 0.277
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0232 0.0651 0.065
Echinococcus multilocularis epidermal growth factor receptor 0.1112 0.3375 0.3374
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Trypanosoma cruzi PAB1-binding protein , putative 0.0043 0.0065 0.0065
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0154 0.0433
Plasmodium vivax basic transcription factor 3b, putative 0.0026 0.0013 0.0037
Schistosoma mansoni zinc finger protein 0.0092 0.0217 0.0216
Trichomonas vaginalis hypothetical protein 0.0025 0.0011 0.0031
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0103 0.0251 0.025
Schistosoma mansoni hypothetical protein 0.0036 0.0044 0.0043
Entamoeba histolytica cysteine proteinase, putative 0.0845 0.2549 0.8891
Trypanosoma brucei PAB1-binding protein , putative 0.0043 0.0065 0.0172
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0027 0.0016 0.0046
Schistosoma mansoni tyrosine kinase 0.0591 0.1763 0.1762
Onchocerca volvulus 0.0097 0.0232 0.0888
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0051 0.0092 0.009
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0046 0.0074 0.0072
Onchocerca volvulus Cathepsin L homolog 0.0845 0.2549 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0232 0.0651 0.1837
Echinococcus multilocularis lysosomal alpha glucosidase 0.0202 0.0556 0.0555
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0521 0.147
Plasmodium vivax multidomain scavenger receptor, putative 0.003 0.0026 0.0085
Loa Loa (eye worm) latrophilin receptor protein 2 0.0176 0.0478 0.0477
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0491 0.1385
Leishmania major hypothetical protein, conserved 0.0038 0.0051 0.0145
Leishmania major cysteine peptidase A (CPA) 0.0845 0.2549 0.7196
Brugia malayi Heterochromatin protein 1 0.0073 0.0159 0.0157
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0232 0.0651 0.065
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0053 0.0096 0.0677
Plasmodium vivax vivapain-1 0.0481 0.1421 0.5565
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0131 0.0339 0.0338
Trypanosoma cruzi cysteine peptidase, putative 0.0249 0.0702 0.0702
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0481 0.1421 0.1421
Trypanosoma brucei ISWI complex protein 0.0038 0.0051 0.0133
Plasmodium falciparum serine repeat antigen 6 0.0232 0.0651 0.2542
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Loa Loa (eye worm) hypothetical protein 0.0333 0.0963 0.0962
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0025 0.0025
Echinococcus multilocularis chromobox protein 1 0.0073 0.0159 0.0157
Brugia malayi beta-lactamase family protein 0.0062 0.0123 0.0122
Mycobacterium ulcerans sulfatase 0.0053 0.0096 0.0677
Schistosoma mansoni nuclear receptor nhr-48 0.0092 0.0217 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0103 0.0251 0.025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0232 0.0651 0.1837
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0463 0.1366 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0845 0.2549 0.2548
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0024 0.0006 0.0005
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0051 0.0092 0.0247
Trypanosoma cruzi PAB1-binding protein , putative 0.0043 0.0065 0.0065
Brugia malayi Calcitonin receptor-like protein seb-1 0.0558 0.1658 0.1657
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0187 0.0186
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0013 0.0037
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0051 0.0092 0.0092
Brugia malayi hypothetical protein 0.0092 0.0217 0.0216
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0025 0.0009 0.0036
Schistosoma mansoni methyl-cpg binding protein mbd 0.0043 0.0065 0.0064
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0024 0.0006 0.0007
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0091 0.0214 0.0212
Echinococcus granulosus thyroid hormone receptor alpha 0.0092 0.0217 0.0216
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0177 0.0482 0.3507
Entamoeba histolytica hypothetical protein 0.0036 0.0044 0.014
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0092 0.0217 0.0216
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0006 0.0005
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0232 0.0651 0.2542
Brugia malayi RNA recognition motif domain containing protein 0.0225 0.0628 0.0626
Brugia malayi Pre-SET motif family protein 0.008 0.018 0.0179
Echinococcus multilocularis ecdysone induced protein 78C 0.0195 0.0536 0.0535
Schistosoma mansoni microtubule-associated protein tau 0.2248 0.6892 0.6891
Giardia lamblia Cathepsin B precursor 0.0232 0.0651 0.1824
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0046 0.0074 0.0072
Giardia lamblia Hypothetical protein 0.0232 0.0651 0.1824
Leishmania major trypanothione reductase 0.0078 0.0173 0.0489
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0001 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0013 0.0037
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0044 0.0043
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0024 0.0006 0.0005
Schistosoma mansoni cathepsin F (C01 family) 0.0597 0.178 0.1779
Echinococcus multilocularis cathepsin b 0.3252 1 1
Brugia malayi RNA binding protein 0.0225 0.0628 0.0626
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.003 0.0025 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0033 0.0034 0.0033
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0024 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Schistosoma mansoni rab6-interacting 0.003 0.0026 0.0024
Schistosoma mansoni hypothetical protein 0.0176 0.0478 0.0477
Giardia lamblia Cathepsin B precursor 0.0232 0.0651 0.1824
Echinococcus granulosus cysteine protease 0.0481 0.1421 0.1419
Brugia malayi T-complex protein 1, beta subunit 0.0024 0.0006 0.0005
Brugia malayi jmjC domain containing protein 0.0024 0.0005 0.0004
Echinococcus granulosus phd:f box containing protein 0.0024 0.0005 0.0004
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0028 0.0018 0.2347
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0071 0.0071
Brugia malayi RNA, U transporter 1 0.0062 0.0123 0.0122
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0119 0.0117
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0037 0.0105
Trichomonas vaginalis penicillin-binding protein, putative 0.0062 0.0123 0.0348
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.0651 0.1837
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Brugia malayi steroid hormone receptor 0.0195 0.0536 0.0535
Schistosoma mansoni jumonji/arid domain-containing protein 0.0099 0.0239 0.0237
Echinococcus granulosus transcription factor btf3 0.0026 0.0013 0.0012
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0005 0.0004
Schistosoma mansoni nuclear receptor 0.0092 0.0217 0.0216
Brugia malayi tailless protein 0.0092 0.0217 0.0216
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0103 0.0251 0.025
Loa Loa (eye worm) hypothetical protein 0.0597 0.178 0.1779
Brugia malayi Inositol-1 0.0028 0.0018 0.0017
Plasmodium falciparum glutathione reductase 0.0078 0.0173 0.0664
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0187 0.0186
Schistosoma mansoni methyl-cpg binding protein mbd 0.0043 0.0065 0.0064
Schistosoma mansoni kinase 0.0037 0.0045 0.0044
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0042 0.0063 0.0063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Schistosoma mansoni cpg binding protein 0.0097 0.0232 0.0231
Onchocerca volvulus 0.0845 0.2549 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0195 0.0536 0.0535
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Mycobacterium tuberculosis Probable sulfatase 0.0053 0.0096 0.0677
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Echinococcus granulosus microtubule associated protein 2 0.2248 0.6892 0.6891
Trichomonas vaginalis alpha-glucosidase, putative 0.0045 0.0071 0.0199
Loa Loa (eye worm) DR-78 0.0092 0.0217 0.0216
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0197 0.0542 0.054
Schistosoma mansoni ap endonuclease 0.0042 0.0063 0.0062
Schistosoma mansoni chromobox protein 0.0073 0.0159 0.0157
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.009 0.0212 0.021
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0016
Brugia malayi hypothetical protein 0.0092 0.0217 0.0216
Schistosoma mansoni hypothetical protein 0.0794 0.239 0.2389
Brugia malayi nuclear hormone receptor 0.0092 0.0217 0.0216
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0187 0.0186
Brugia malayi Thioredoxin reductase 0.0078 0.0173 0.0172
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0708 0.2125 0.2125
Mycobacterium ulcerans glutaminase 0.0206 0.0569 0.4145
Echinococcus multilocularis chromobox protein 1 0.0073 0.0159 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Brugia malayi MH1 domain containing protein 0.0027 0.0015 0.0014
Plasmodium vivax vivapain-2 0.0845 0.2549 1
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0027 0.0016 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0022 0.0062
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0123 0.0313 0.0311
Echinococcus multilocularis tar DNA binding protein 0.0225 0.0628 0.0626
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0045 0.0071 0.0199
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0063 0.0233
Giardia lamblia Hypothetical protein 0.0232 0.0651 0.1824
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.008 0.0179 0.0681
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Brugia malayi Cathepsin L-like precursor 0.0597 0.178 0.1779
Loa Loa (eye worm) fibroinase 0.0845 0.2549 0.2548
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0195 0.0536 0.2082
Brugia malayi intermediate filament protein 0.0024 0.0006 0.0005
Echinococcus multilocularis cathepsin b 0.3252 1 1
Schistosoma mansoni intermediate filament proteins 0.0024 0.0006 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0197 0.0542 0.054
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Loa Loa (eye worm) TK/EGFR protein kinase 0.1112 0.3375 0.3374
Echinococcus granulosus polycomb protein SCMH1 0.008 0.0179 0.0178
Trichomonas vaginalis alpha-glucosidase, putative 0.0045 0.0071 0.0199
Loa Loa (eye worm) runx1 0.0042 0.0062 0.006
Trichomonas vaginalis D-aminoacylase, putative 0.0062 0.0123 0.0348
Schistosoma mansoni hypothetical protein 0.0494 0.1461 0.146
Echinococcus multilocularis dnaJ subfamily B 0.0794 0.239 0.2389
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0053 0.0096 0.0271
Entamoeba histolytica cysteine protease, putative 0.0845 0.2549 0.8891
Echinococcus granulosus FTZ F1 alpha 0.0195 0.0536 0.0535
Brugia malayi jmjC domain containing protein 0.0024 0.0005 0.0004
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0024 0.0006 0.0007
Schistosoma mansoni nuclear hormone receptor 0.0092 0.0217 0.0216
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0232 0.0651 0.2542
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.008 0.018 0.0179
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0176 0.0478 0.0477
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0119 0.0117
Loa Loa (eye worm) hypothetical protein 0.0073 0.0159 0.0158
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0016
Schistosoma mansoni nuclear hormone receptor 0.0092 0.0217 0.0216
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0187 0.0186
Entamoeba histolytica cysteine proteinase 2 0.0481 0.1421 0.4948
Echinococcus granulosus mothers against decapentaplegic 5 0.0027 0.0015 0.0014
Echinococcus granulosus SAM and MBT domain containing protein 0.008 0.0179 0.0178
Echinococcus granulosus neuropeptide s receptor 0.0917 0.2771 0.277
Entamoeba histolytica cysteine protease, putative 0.0232 0.0651 0.226
Trypanosoma cruzi polo-like protein kinase, putative 0.0071 0.0154 0.0154
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0119 0.0117
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Schistosoma mansoni inositol monophosphatase 0.0028 0.0018 0.0017
Trypanosoma cruzi transcription factor btf3, putative 0.0026 0.0013 0.0013
Entamoeba histolytica hypothetical protein 0.0026 0.0013 0.0033
Schistosoma mansoni smad1 5 8 and 0.0027 0.0015 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0232 0.0651 0.1837
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0232 0.0651 0.2542
Onchocerca volvulus Cathepsin L homolog 0.0845 0.2549 1
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0042 0.0063 0.0435
Schistosoma mansoni ap endonuclease 0.0042 0.0063 0.0062
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0006 0.0005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0195 0.0536 0.0535
Loa Loa (eye worm) hypothetical protein 0.0062 0.0123 0.0122
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.0651 0.065
Trypanosoma brucei glucosidase, putative 0.0045 0.0071 0.0189
Brugia malayi nuclear hormone receptor family member odr-7 0.0092 0.0217 0.0216
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0069 0.0193
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0195 0.0536 0.0535
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0042 0.0063 0.0062
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0395 0.1154 0.8443
Echinococcus granulosus cathepsin L 0.0232 0.0651 0.065
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0232 0.0651 0.1837
Brugia malayi hypothetical protein 0.003 0.0026 0.0024
Plasmodium vivax serine-repeat antigen (SERA) 0.0232 0.0651 0.2542
Brugia malayi TAR-binding protein 0.0225 0.0628 0.0626
Loa Loa (eye worm) hypothetical protein 0.0024 0.0006 0.0005
Echinococcus multilocularis mitogen activated protein kinase 3 0.0051 0.0092 0.009
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0092 0.0217 0.0216
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3252 1 1
Echinococcus granulosus nuclear receptor nhr 48 0.0092 0.0217 0.0216
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0027 0.0016 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0037 0.0105
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0481 0.1421 0.1419
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0062 0.0123 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0176 0.0478 0.0477
Loa Loa (eye worm) hypothetical protein 0.0053 0.0096 0.0095
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.003 0.0025 0.0081
Toxoplasma gondii NAC domain-containing protein 0.0026 0.0013 0.0026
Plasmodium vivax JmjC domain containing protein 0.0024 0.0005 0.0005
Mycobacterium ulcerans hydrolase 0.0053 0.0096 0.0677
Brugia malayi Cathepsin L-like cysteine proteinase 0.0597 0.178 0.1779
Echinococcus multilocularis cathepsin L cysteine protease 0.0845 0.2549 0.2548
Onchocerca volvulus 0.0117 0.0293 0.1129
Echinococcus multilocularis ubiquitin specific protease 41 0.003 0.0025 0.0024
Echinococcus multilocularis epidermal growth factor receptor 0.0598 0.1782 0.1781
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0232 0.0651 0.065
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0159 0.0447
Trichomonas vaginalis alpha-glucosidase, putative 0.0045 0.0071 0.0199
Brugia malayi cathepsin L-like precursor 0.0597 0.178 0.1779
Schistosoma mansoni bromodomain containing protein 0.0164 0.0441 0.044
Brugia malayi Cathepsin L-like precursor 0.0845 0.2549 0.2548
Schistosoma mansoni chromobox protein 0.0073 0.0159 0.0157
Trypanosoma cruzi polo-like protein kinase, putative 0.0071 0.0154 0.0154
Brugia malayi hypothetical protein 0.0043 0.0065 0.0064
Mycobacterium ulcerans arylsulfatase AtsB 0.0053 0.0096 0.0677
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0027 0.0016 0.0014
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0045 0.0071 0.0199
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0027 0.0016 0.197
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0119 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.0651 0.1837
Brugia malayi serine/threonine-protein kinase plk-2 0.0071 0.0154 0.0152
Schistosoma mansoni glutaminase 0.0206 0.0569 0.0567
Brugia malayi jmjC domain containing protein 0.0024 0.0005 0.0004
Giardia lamblia Hypothetical protein 0.0053 0.0096 0.0255
Echinococcus granulosus dnaJ subfamily B 0.0794 0.239 0.2389
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0034 0.0037 0.0036
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0197 0.0542 0.054
Plasmodium falciparum ataxin-2 like protein, putative 0.0043 0.0065 0.0239
Brugia malayi Sulfatase family protein 0.0053 0.0096 0.0095
Brugia malayi orphan nuclear receptor NR2E1 0.0092 0.0217 0.0216
Toxoplasma gondii ABC1 family protein 0.0062 0.0123 0.0337
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0092 0.0217 0.0216
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0033 0.0034 0.0033
Brugia malayi Furin-like cysteine rich region family protein 0.1112 0.3375 0.3374
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0197 0.0542 0.054
Mycobacterium ulcerans beta-lactamase 0.0062 0.0123 0.0877
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0154 0.0433
Schistosoma mansoni phd/f-box containing protein 0.0024 0.0005 0.0004
Trypanosoma cruzi cysteine peptidase, putative 0.0957 0.2894 0.2894
Echinococcus granulosus lamin dm0 0.0024 0.0006 0.0005
Onchocerca volvulus Serine\/threonine kinase homolog 0.0071 0.0154 0.0579
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0232 0.0651 0.2542
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0481 0.1421 0.4003
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0119 0.0842
Loa Loa (eye worm) glutaminase 2 0.0206 0.0569 0.0567
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3252 1 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0123 0.0122
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0784 0.2212
Plasmodium falciparum cysteine proteinase falcipain 3 0.0845 0.2549 1
Echinococcus multilocularis GPCR, family 2 0.0176 0.0478 0.0477
Loa Loa (eye worm) TAR-binding protein 0.0225 0.0628 0.0626
Plasmodium vivax vivapain-2 0.0845 0.2549 1
Trichomonas vaginalis conserved hypothetical protein 0.0232 0.0651 0.1837
Echinococcus multilocularis zinc finger protein 0.0055 0.0102 0.01
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Brugia malayi beta-lactamase family protein 0.0062 0.0123 0.0122
Brugia malayi glutathione reductase 0.0078 0.0173 0.0172
Echinococcus multilocularis jumonji domain containing 1A 0.0024 0.0005 0.0004
Mycobacterium ulcerans arylsulfatase, AslA 0.0053 0.0096 0.0677
Brugia malayi Bromodomain containing protein 0.0194 0.0533 0.0531
Giardia lamblia Cysteine protease 0.0232 0.0651 0.1824
Giardia lamblia Cysteine protease 0.0232 0.0651 0.1824
Loa Loa (eye worm) nuclear hormone receptor 0.0092 0.0217 0.0216
Echinococcus multilocularis mitogen activated protein kinase 0.0051 0.0092 0.009
Schistosoma mansoni smad1 5 8 and 0.0027 0.0015 0.0014
Echinococcus multilocularis muscleblind protein 1 0.0243 0.0684 0.0683
Plasmodium falciparum serine repeat antigen 3 0.0232 0.0651 0.2542
Schistosoma mansoni hypothetical protein 0.0381 0.1112 0.1111
Loa Loa (eye worm) hypothetical protein 0.0558 0.1658 0.1657
Echinococcus granulosus methyl CpG binding domain protein 2 0.0043 0.0065 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0845 0.2549 0.7196
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.003 0.0025 0.0024
Brugia malayi ecdysone receptor 0.0092 0.0217 0.0216
Brugia malayi cathepsin Z-like cysteine proteinase 0.0232 0.0651 0.065
Echinococcus granulosus intermediate filament protein 0.0024 0.0006 0.0005
Brugia malayi MH1 domain containing protein 0.0027 0.0015 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0195 0.0536 0.0535
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Leishmania major cathepsin L-like protease 0.0845 0.2549 0.7196
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0028 0.0018 0.005
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0006 0.0005
Giardia lamblia PHD finger protein 15 0.0073 0.0159 0.0433
Echinococcus multilocularis musashi 0.0024 0.0006 0.0005
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0045 0.0071 0.0233
Echinococcus granulosus cathepsin l1 0.0597 0.178 0.1779
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0103 0.0251 0.025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0232 0.0651 0.1837
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0491 0.1385
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0948 0.2867 1
Schistosoma mansoni lamin 0.0024 0.0006 0.0005
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0249 0.0702 0.0701
Toxoplasma gondii PHD-finger domain-containing protein 0.0073 0.0159 0.0438
Brugia malayi nuclear receptor RXR 0.0092 0.0217 0.0216
Entamoeba histolytica serine/threonine protein kinase, putative 0.0071 0.0154 0.0522
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0481 0.1421 0.1419
Schistosoma mansoni hypothetical protein 0.0052 0.0093 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0195 0.0536 0.0535
Loa Loa (eye worm) hypothetical protein 0.0381 0.1112 0.1111
Brugia malayi Cathepsin L-like precursor 0.0845 0.2549 0.2548
Onchocerca volvulus 0.0845 0.2549 1
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0051 0.0092 0.0092
Brugia malayi Cathepsin L-like precursor 0.0845 0.2549 0.2548
Toxoplasma gondii exonuclease III APE 0.0042 0.0063 0.0167
Schistosoma mansoni cathepsin S (C01 family) 0.0232 0.0651 0.065
Brugia malayi mbt repeat family protein 0.008 0.0179 0.0178
Trypanosoma brucei cysteine peptidase C (CPC) 0.1166 0.3542 1
Echinococcus granulosus lysosomal alpha glucosidase 0.0202 0.0556 0.0555
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0177 0.0482 0.3507
Schistosoma mansoni hypothetical protein 0.061 0.182 0.1819
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.003 0.0025 0.0071
Mycobacterium tuberculosis Probable dehydrogenase 0.0177 0.0482 0.3507
Entamoeba histolytica cysteine proteinase, putative 0.0481 0.1421 0.4948
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0025 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0037 0.0105
Giardia lamblia Hypothetical protein 0.0053 0.0096 0.0255
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.003 0.0025 0.0025
Schistosoma mansoni cpg binding protein 0.0107 0.0264 0.0263
Loa Loa (eye worm) hypothetical protein 0.0043 0.0065 0.0064
Loa Loa (eye worm) jmjC domain-containing protein 0.0099 0.0239 0.0237
Trypanosoma brucei polo-like protein kinase 0.0071 0.0154 0.0423
Plasmodium vivax glutathione reductase, putative 0.0078 0.0173 0.0664
Trichomonas vaginalis D-aminoacylase, putative 0.0062 0.0123 0.0348
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Onchocerca volvulus 0.0504 0.1494 0.585
Echinococcus granulosus inositol monophosphatase 1 0.0028 0.0018 0.0017
Schistosoma mansoni tar DNA-binding protein 0.0225 0.0628 0.0626
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0197 0.0543 0.3957
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0195 0.0536 0.0535
Onchocerca volvulus Protein ultraspiracle homolog 0.0195 0.0536 0.2082
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Giardia lamblia Kinase, CMGC MAPK 0.0051 0.0092 0.0242
Toxoplasma gondii FATC domain-containing protein 0.003 0.0025 0.006
Echinococcus granulosus transcription factor Dp 1 0.0026 0.0014 0.0013
Loa Loa (eye worm) cysteine protease 0.0845 0.2549 0.2548
Trypanosoma cruzi cruzipain precursor, putative 0.0249 0.0702 0.0702
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0042 0.0063 0.0207
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0071 0.0154 0.0152
Brugia malayi Glycosyl hydrolases family 31 protein 0.0202 0.0556 0.0555
Giardia lamblia Cathepsin L precursor 0.0232 0.0651 0.1824
Plasmodium falciparum phd finger protein, putative 0.0073 0.0159 0.0609
Trypanosoma brucei hypothetical protein, conserved 0.0062 0.0123 0.0337
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0491 0.1385
Leishmania major hypothetical protein, conserved 0.0043 0.0065 0.0183
Echinococcus granulosus insulin receptor 0.0355 0.1032 0.1031
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0062 0.0125 0.0123
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0062 0.0125 0.0123
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0027 0.0016 0.0044
Loa Loa (eye worm) intermediate filament protein 0.0024 0.0006 0.0005
Plasmodium falciparum serine repeat antigen 1 0.0232 0.0651 0.2542
Trypanosoma cruzi major cysteine proteinase, putative 0.0232 0.0651 0.0651
Loa Loa (eye worm) hypothetical protein 0.0176 0.0478 0.0477
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0046 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0102 0.0249 0.0248
Echinococcus granulosus survival motor neuron protein 1 0.025 0.0705 0.0704
Echinococcus granulosus PHD finger protein rhinoceros 0.0073 0.0159 0.0158
Echinococcus granulosus histone lysine methyltransferase setb 0.0123 0.0313 0.0311
Schistosoma mansoni cpg binding protein 0.0107 0.0264 0.0263
Echinococcus granulosus Nuclear hormone receptor HR96 0.0092 0.0217 0.0216
Brugia malayi cathepsin L-like cysteine proteinase 0.0232 0.0651 0.065
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0027 0.0016 0.0086
Loa Loa (eye worm) hypothetical protein 0.0751 0.2257 0.2256
Echinococcus multilocularis neuropeptide s receptor 0.0917 0.2771 0.277
Brugia malayi PHD-finger family protein 0.0068 0.0143 0.0142
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0051 0.009 0.0088
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0028 0.0018 0.005
Schistosoma mansoni tyrosine kinase 0.0355 0.1032 0.1031
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.0025 0.0024
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0195 0.0536 0.0535
Giardia lamblia Cathepsin B precursor 0.1166 0.3542 1
Brugia malayi nuclear receptor NHR-88 0.0092 0.0217 0.0216
Brugia malayi cathepsin L precursor 0.0232 0.0651 0.065
Schistosoma mansoni tar DNA-binding protein 0.0225 0.0628 0.0626
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Brugia malayi cathepsin F-like cysteine proteinase 0.0232 0.0651 0.065
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0232 0.0651 0.1837
Echinococcus granulosus ecdysone induced protein 78C 0.0195 0.0536 0.0535
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0062 0.0123 0.0877
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Echinococcus granulosus lipoxygenase domain containing protein 0.003 0.0026 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0013 0.0037
Echinococcus granulosus thioredoxin glutathione reductase 0.0078 0.0173 0.0172
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0845 0.2549 0.7196
Echinococcus granulosus cathepsin b 0.3252 1 1
Echinococcus granulosus Polycystic kidney disease protein 0.003 0.0026 0.0024
Trypanosoma cruzi cysteine peptidase, putative 0.0957 0.2894 0.2894
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0195 0.0536 0.0535
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0208 0.0577 0.0576
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0024 0.0005 0.0004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0195 0.0536 0.0535
Loa Loa (eye worm) ICD-1 protein 0.0026 0.0013 0.0012
Brugia malayi Bromodomain containing protein 0.0079 0.0177 0.0176
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0232 0.0651 0.2542
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.008 0.018 0.0179
Mycobacterium leprae Probable lipase LipE 0.0062 0.0123 0.0877
Loa Loa (eye worm) hypothetical protein 0.0053 0.0096 0.0095
Plasmodium vivax unspecified product 0.0249 0.0702 0.2742
Loa Loa (eye worm) hypothetical protein 0.0243 0.0684 0.0683
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0313 0.0311
Trichomonas vaginalis mercuric reductase, putative 0.0027 0.0016 0.0044
Brugia malayi nuclear hormone receptor family member nhr-6 0.0092 0.0217 0.0216
Mycobacterium ulcerans lipase LipD 0.0062 0.0123 0.0877
Plasmodium falciparum T-complex protein 1 subunit beta 0.0024 0.0006 0.0007
Trypanosoma brucei RNA helicase, putative 0.0068 0.0143 0.0393
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0197 0.0542 0.054
Echinococcus granulosus cathepsin l1 0.0845 0.2549 0.2548
Plasmodium vivax SET domain protein, putative 0.008 0.018 0.0692
Onchocerca volvulus 0.0092 0.0217 0.0829
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.003 0.0025 0.0071
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Trypanosoma cruzi ISWI complex protein 0.0038 0.0051 0.0051
Trichomonas vaginalis alpha-glucosidase, putative 0.0045 0.0071 0.0199
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0845 0.2549 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Echinococcus multilocularis geminin 0.061 0.182 0.1819
Echinococcus granulosus cpg binding protein 0.0107 0.0264 0.0263
Loa Loa (eye worm) thioredoxin reductase 0.0078 0.0173 0.0172
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0027 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0068 0.0143 0.0142
Brugia malayi Cathepsin L-like precursor 0.0597 0.178 0.1779
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0071 0.0154 0.0152
Giardia lamblia Cathepsin B precursor 0.1166 0.3542 1
Plasmodium falciparum glutathione reductase 0.0027 0.0016 0.0046
Brugia malayi Papain family cysteine protease containing protein 0.0845 0.2549 0.2548
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Loa Loa (eye worm) heterochromatin protein 1 0.0073 0.0159 0.0157
Loa Loa (eye worm) hypothetical protein 0.0845 0.2549 0.2548
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0046 0.0074 0.0197
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0092 0.0217 0.0216
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0232 0.0651 0.2542
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0195 0.0536 0.0535
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0176 0.0478 0.0477
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0232 0.0651 0.065
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0546 0.1621 0.162
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0027 0.0016 0.0033
Schistosoma mansoni jumonji domain containing protein 0.0024 0.0005 0.0004
Onchocerca volvulus 0.0333 0.0963 0.3763
Echinococcus granulosus tar DNA binding protein 0.0225 0.0628 0.0626
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0232 0.0651 0.2542
Echinococcus granulosus geminin 0.061 0.182 0.1819
Trypanosoma brucei transcription factor BTF3, putative 0.0026 0.0013 0.0026
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0232 0.0651 0.1824
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0092 0.0258
Plasmodium vivax hypothetical protein, conserved 0.003 0.0025 0.0081
Echinococcus multilocularis muscleblind protein 0.0243 0.0684 0.0683
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.0651 0.1837
Brugia malayi exodeoxyribonuclease III family protein 0.0042 0.0063 0.0062
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0784 0.2212
Echinococcus multilocularis thioredoxin glutathione reductase 0.0078 0.0173 0.0172
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0092 0.0258
Giardia lamblia Cysteine protease 0.0232 0.0651 0.1824
Entamoeba histolytica hypothetical protein 0.0232 0.0651 0.226
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0027 0.0016 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0232 0.0651 0.1837
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.003 0.0025 0.0071
Brugia malayi Papain family cysteine protease containing protein 0.0232 0.0651 0.065
Mycobacterium tuberculosis Conserved protein 0.0062 0.0123 0.0877
Loa Loa (eye worm) transcription factor SMAD2 0.0393 0.1149 0.1148
Toxoplasma gondii LsmAD domain-containing protein 0.0043 0.0065 0.0172
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0177 0.0482 0.3507
Schistosoma mansoni protein phosphatase 2C 0.0024 0.0005 0.0004
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0195 0.0536 0.0535
Entamoeba histolytica hypothetical protein 0.0036 0.0044 0.014
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.0651 0.065
Onchocerca volvulus Glucosylceramidase homolog 0.018 0.0491 0.1906
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0119 0.0335
Echinococcus multilocularis cathepsin L 0.0232 0.0651 0.065
Brugia malayi Nuclear hormone receptor-like 1 0.0103 0.0251 0.025
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0784 0.2212
Loa Loa (eye worm) T-complex protein 1 0.0024 0.0006 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0195 0.0536 0.0535
Entamoeba histolytica cysteine proteinase, putative 0.0597 0.178 0.6202
Echinococcus granulosus lysine specific demethylase 5A 0.0099 0.0239 0.0237
Loa Loa (eye worm) beta-lactamase 0.0062 0.0123 0.0122
Onchocerca volvulus Cathepsin F homolog 0.0845 0.2549 1
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0491 0.1385
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0022 0.0062
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0195 0.0536 0.0535
Echinococcus multilocularis microtubule associated protein 2 0.2248 0.6892 0.6891
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0103 0.0251 0.025
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Brugia malayi MH2 domain containing protein 0.0027 0.0015 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0195 0.0536 0.0535
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Schistosoma mansoni thyroid hormone receptor 0.0195 0.0536 0.0535
Brugia malayi Cathepsin L-like precursor 0.0845 0.2549 0.2548
Echinococcus granulosus ubiquitin specific protease 41 0.003 0.0025 0.0024
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0154 0.0433
Echinococcus granulosus cathepsin L 0.0481 0.1421 0.1419
Brugia malayi Doublecortin family protein 0.003 0.0026 0.0024
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0154 0.0433
Loa Loa (eye worm) inositol-1 0.0028 0.0018 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.003 0.0025 0.0024
Onchocerca volvulus 0.0845 0.2549 1
Echinococcus granulosus epidermal growth factor receptor 0.0598 0.1782 0.1781
Echinococcus multilocularis lipoxygenase domain containing protein 0.003 0.0026 0.0024
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.0651 0.065
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0062 0.0123 0.0877
Schistosoma mansoni myelin transcription factor 1 myt1 0.0091 0.0214 0.0212
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0784 0.2212
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0004
Schistosoma mansoni lipoxygenase 0.0077 0.0171 0.017
Echinococcus granulosus epidermal growth factor receptor 0.1112 0.3375 0.3374
Schistosoma mansoni tsg101-related 0.0044 0.0067 0.0066
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0078 0.0173 0.1241
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0037 0.0105
Toxoplasma gondii PHD-finger domain-containing protein 0.0073 0.0159 0.0438
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.003 0.0025 0.0024
Schistosoma mansoni retinoic acid receptor RXR 0.0195 0.0536 0.0535
Schistosoma mansoni cathepsin F (C01 family) 0.0845 0.2549 0.2548
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.008 0.0179 0.0178
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0024 0.0005 0.0004
Schistosoma mansoni smad1 5 8 and 0.0027 0.0015 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0195 0.0536 0.0535
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0232 0.0651 0.2542
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0232 0.0651 0.065
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.0651 0.065
Loa Loa (eye worm) hypothetical protein 0.0041 0.0059 0.0058
Brugia malayi Glycosyl hydrolases family 31 protein 0.0045 0.0071 0.007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Schistosoma mansoni cathepsin s 0.0249 0.0702 0.0701
Echinococcus multilocularis transcription factor Dp 1 0.0026 0.0014 0.0013
Echinococcus granulosus zinc finger protein 0.0055 0.0102 0.01
Toxoplasma gondii cathepsin B 0.1166 0.3542 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0195 0.0536 0.0535
Plasmodium falciparum serine repeat antigen 8 0.0232 0.0651 0.2542
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0232 0.0651 0.1824
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0096 0.0231 0.0229
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0027 0.0016 0.0033
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0016
Brugia malayi jmjC domain containing protein 0.024 0.0675 0.0674
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0024 0.0006 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Giardia lamblia Cathepsin L precursor 0.0232 0.0651 0.1824
Trichomonas vaginalis set domain proteins, putative 0.0621 0.1853 0.5232
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0784 0.2212
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Mycobacterium ulcerans esterase/lipase LipP 0.0062 0.0123 0.0877
Echinococcus multilocularis lysosomal alpha glucosidase 0.0202 0.0556 0.0555
Brugia malayi hypothetical protein 0.0036 0.0044 0.0043
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0027 0.0016 1
Brugia malayi MH2 domain containing protein 0.0027 0.0015 0.0014
Schistosoma mansoni hypothetical protein 0.0051 0.009 0.0089
Onchocerca volvulus 0.0597 0.178 0.6974
Toxoplasma gondii cathepsin CPC1 0.0232 0.0651 0.1828
Brugia malayi nuclear receptor NHR-67 0.0092 0.0217 0.0216
Loa Loa (eye worm) PHD-finger family protein 0.0052 0.0093 0.0091
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0195 0.0536 0.0535
Echinococcus granulosus Nuclear hormone receptor HR96 0.0092 0.0217 0.0216
Loa Loa (eye worm) hypothetical protein 0.003 0.0025 0.0024
Loa Loa (eye worm) RNA binding protein 0.0225 0.0628 0.0626
Giardia lamblia Cysteine protease 0.0232 0.0651 0.1824
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0042 0.0063 0.0062
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0481 0.1421 0.4003
Echinococcus multilocularis PHD finger protein rhinoceros 0.0073 0.0159 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.0651 0.1837
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0195 0.0536 0.0535
Schistosoma mansoni RAR-like nuclear receptor 0.0195 0.0536 0.0535
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0195 0.0536 0.0535
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0232 0.0651 0.1837
Loa Loa (eye worm) hypothetical protein 0.0333 0.0963 0.0962
Brugia malayi beta-lactamase 0.0062 0.0123 0.0122
Echinococcus multilocularis insulin receptor 0.0355 0.1032 0.1031
Brugia malayi AF-10 protein 0.0024 0.0006 0.0005
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0042 0.0063 0.0179
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0037 0.0105
Echinococcus granulosus Smad4 0.0027 0.0015 0.0014
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0195 0.0536 0.0535
Leishmania major cathepsin L-like protease 0.0845 0.2549 0.7196
Brugia malayi fibroinase precursor 0.0232 0.0651 0.065
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0025 0.0009 0.0036
Echinococcus multilocularis cpg binding protein 0.0107 0.0264 0.0263
Echinococcus granulosus serine protein kinase ATM 0.003 0.0025 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Loa Loa (eye worm) PHD-finger family protein 0.0073 0.0159 0.0158
Echinococcus granulosus chromobox protein 1 0.0073 0.0159 0.0157
Onchocerca volvulus 0.0092 0.0217 0.0829
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Mycobacterium tuberculosis Probable lipase LipD 0.0062 0.0123 0.0877
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0275 0.0784 0.0782
Loa Loa (eye worm) hypothetical protein 0.0103 0.0251 0.025
Trypanosoma cruzi cysteine peptidase, putative 0.0957 0.2894 0.2894
Trichomonas vaginalis penicillin-binding protein, putative 0.0062 0.0123 0.0348
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Plasmodium vivax serine-repeat antigen (SERA) 0.0232 0.0651 0.2542
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0195 0.0536 0.0535
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0598 0.1782 0.1781
Loa Loa (eye worm) doublecortin family protein 0.003 0.0026 0.0024
Brugia malayi hypothetical protein 0.003 0.0026 0.0024
Mycobacterium leprae conserved hypothetical protein 0.0062 0.0123 0.0877
Plasmodium falciparum serine repeat antigen 4 0.0232 0.0651 0.2542
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Loa Loa (eye worm) hypothetical protein 0.008 0.0179 0.0178
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0063 0.0178
Echinococcus granulosus neuropeptide receptor A26 0.0917 0.2771 0.277
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0232 0.0651 0.226
Trypanosoma cruzi major cysteine proteinase, putative 0.0344 0.0996 0.0996
Trichomonas vaginalis ap endonuclease, putative 0.0042 0.0063 0.0178
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0027 0.0016 0.0033
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0197 0.0543 0.3957
Brugia malayi hypothetical protein 0.025 0.0705 0.0704
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0024 0.0006 0.0016
Schistosoma mansoni nuclear receptor 0.0092 0.0217 0.0216
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0845 0.2549 0.2548
Trypanosoma cruzi cysteine proteinase, putative 0.0481 0.1421 0.1421
Echinococcus multilocularis jumonji domain containing protein 0.0102 0.0248 0.0247
Leishmania major cathepsin L-like protease 0.0845 0.2549 0.7196
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Trichomonas vaginalis maltase-glucoamylase, putative 0.0045 0.0071 0.0199
Echinococcus granulosus JmjC domain containing protein 4 0.0024 0.0005 0.0004
Giardia lamblia Cathepsin B precursor 0.0232 0.0651 0.1824
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Loa Loa (eye worm) MH2 domain-containing protein 0.0027 0.0015 0.0014
Treponema pallidum NADH oxidase 0.0027 0.0016 0.0041
Brugia malayi PHD-finger family protein 0.0034 0.0038 0.0037
Loa Loa (eye worm) hypothetical protein 0.0113 0.0281 0.028
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0046 0.0074 0.0072
Trypanosoma cruzi cysteine peptidase, putative 0.0845 0.2549 0.2549
Schistosoma mansoni alpha-glucosidase 0.0174 0.0469 0.0468
Mycobacterium tuberculosis Conserved protein 0.0062 0.0123 0.0877
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0016
Echinococcus granulosus mitogen activated protein kinase 3 0.0051 0.0092 0.009
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0027 0.0015 0.0014
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.008 0.018 0.0498
Onchocerca volvulus 0.0845 0.2549 1
Brugia malayi hypothetical protein 0.0504 0.1494 0.1493
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0197 0.0542 0.054
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0062 0.0123 0.0122
Schistosoma mansoni hypothetical protein 0.0038 0.0051 0.005
Echinococcus granulosus jumonji domain containing protein 0.0102 0.0248 0.0247
Trypanosoma brucei protein kinase, putative 0.0051 0.0092 0.0247
Giardia lamblia Cathepsin L precursor 0.0232 0.0651 0.1824
Giardia lamblia Cathepsin B precursor 0.0232 0.0651 0.1824
Mycobacterium ulcerans arylsulfatase AtsD 0.0053 0.0096 0.0677
Schistosoma mansoni hypothetical protein 0.003 0.0026 0.0024
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.003 0.0025 0.0024
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0043 0.0065 0.0064
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0154 0.0433
Schistosoma mansoni hypothetical protein 0.0176 0.0478 0.0477
Loa Loa (eye worm) hypothetical protein 0.0243 0.0684 0.0683
Brugia malayi Cathepsin L-like precursor 0.0249 0.0702 0.0701
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0232 0.0651 0.1837
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.3252 1 1
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0491 0.1385
Brugia malayi Cathepsin L-like precursor 0.0845 0.2549 0.2548
Echinococcus multilocularis RUN 0.003 0.0026 0.0024
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0071 0.0154 0.0433
Loa Loa (eye worm) hypothetical protein 0.0052 0.0094 0.0093
Schistosoma mansoni tyrosine kinase 0.0355 0.1032 0.1031
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0249 0.0702 0.0701
Echinococcus multilocularis mothers against decapentaplegic 5 0.0027 0.0015 0.0014
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0197 0.0542 0.054
Onchocerca volvulus 0.0032 0.0032 0.01
Loa Loa (eye worm) mbt repeat family protein 0.008 0.0179 0.0178
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0195 0.0536 0.0535
Entamoeba histolytica cysteine protease, putative 0.0232 0.0651 0.226
Brugia malayi Nuclear hormone receptor E75 0.0092 0.0217 0.0216
Echinococcus multilocularis lysine specific demethylase 6a 0.0024 0.0005 0.0004
Loa Loa (eye worm) jmjC domain-containing protein 0.0151 0.04 0.0399
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0231 0.0649 0.0648
Echinococcus multilocularis snurportin 1 0.0231 0.0649 0.0648
Echinococcus granulosus muscleblind protein 0.0243 0.0684 0.0683
Onchocerca volvulus Bile acid receptor homolog 0.0195 0.0536 0.2082
Entamoeba histolytica cysteine proteinase, putative 0.0481 0.1421 0.4948
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0195 0.0536 0.0535
Echinococcus multilocularis survival motor neuron protein 1 0.025 0.0705 0.0704
Giardia lamblia Cathepsin L precursor 0.0232 0.0651 0.1824
Entamoeba histolytica cysteine protease, putative 0.0232 0.0651 0.226
Loa Loa (eye worm) Smad1 0.0027 0.0015 0.0014
Trichomonas vaginalis inositol monophosphatase, putative 0.0028 0.0018 0.005
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0046 0.0074 0.0072
Brugia malayi Muscleblind-like protein 0.0243 0.0684 0.0683
Schistosoma mansoni jumonji domain containing protein 0.0191 0.0522 0.0521
Echinococcus granulosus cathepsin b 0.3252 1 1
Echinococcus multilocularis phd:f box containing protein 0.0024 0.0005 0.0004
Trypanosoma cruzi trypanothione reductase, putative 0.0078 0.0173 0.0173
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0044
Brugia malayi jmjC domain containing protein 0.0024 0.0005 0.0004
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0045 0.0071 0.0189
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0018 0.0018
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0197 0.0543 0.3957
Leishmania major T-complex protein 1, beta subunit, putative 0.0024 0.0006 0.0017
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0092 0.0217 0.0216
Giardia lamblia Cathepsin B precursor 0.1166 0.3542 1
Loa Loa (eye worm) TK/INSR protein kinase 0.0355 0.1032 0.1031
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0005 0.0004
Trypanosoma cruzi trypanothione reductase, putative 0.0027 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Echinococcus granulosus peregrin 0.0079 0.0177 0.0176
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0855 0.2579 0.2578
Schistosoma mansoni tar DNA-binding protein 0.0225 0.0628 0.0626
Treponema pallidum exodeoxyribonuclease (exoA) 0.0042 0.0063 0.0207
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.003 0.0025 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0597 0.178 0.5024
Loa Loa (eye worm) hypothetical protein 0.0232 0.0651 0.065
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0059 0.0166
Echinococcus granulosus jumonji domain containing 1A 0.0024 0.0005 0.0004
Schistosoma mansoni rab6-interacting 0.003 0.0026 0.0024
Echinococcus multilocularis neutral alpha glucosidase AB 0.0045 0.0071 0.007
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0092 0.0217 0.0216
Brugia malayi Steroid receptor seven-up type 2 0.0195 0.0536 0.0535
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0045 0.0071 0.0233
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0177 0.0482 0.3507
Trichomonas vaginalis glutathione reductase, putative 0.0027 0.0016 0.0044
Echinococcus granulosus mixed lineage leukemia protein mll 0.0027 0.0016 0.0014
Onchocerca volvulus 0.008 0.0179 0.0681
Onchocerca volvulus 0.0062 0.0123 0.0461
Loa Loa (eye worm) hypothetical protein 0.3252 1 1
Plasmodium falciparum JmjC domain-containing protein, putative 0.0024 0.0005 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0027 0.0016 0.0016
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0024 0.0006 0.0005
Echinococcus granulosus cathepsin L cysteine protease 0.0481 0.1421 0.1419
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0034 0.0037 0.0036
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0027 0.0016 0.0014
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0463 0.1366 1
Loa Loa (eye worm) hypothetical protein 0.0249 0.0702 0.0701
Leishmania major cathepsin L-like protease 0.0845 0.2549 0.7196
Loa Loa (eye worm) hypothetical protein 0.0034 0.0038 0.0037
Echinococcus multilocularis Polycystic kidney disease protein 0.003 0.0026 0.0024
Echinococcus multilocularis FTZ F1 alpha 0.0195 0.0536 0.0535
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0046 0.0074 0.0074
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0092 0.009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0027 0.0016 0.0016
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0463 0.1366 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0037 0.0105
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0024 0.0006 0.0006
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0323 0.0932 0.0931
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0275 0.0784 0.0782
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0027 0.0016 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Echinococcus granulosus fetal alzheimer antigen falz 0.0062 0.0125 0.0123
Brugia malayi nuclear receptor NHR-88 0.0195 0.0536 0.0535
Schistosoma mansoni serine/threonine protein kinase 0.0071 0.0154 0.0152
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.003 0.0025 0.0024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0195 0.0536 0.0535
Trichomonas vaginalis chromobox protein, putative 0.0044 0.0069 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.0651 0.1837
Loa Loa (eye worm) hypothetical protein 0.0126 0.0321 0.032
Entamoeba histolytica cysteine proteinase 1, putative 0.0481 0.1421 0.4948
Loa Loa (eye worm) hypothetical protein 0.0024 0.0005 0.0004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0195 0.0536 0.0535
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0195 0.0536 0.0535
Brugia malayi nuclear receptor RXR 0.0103 0.0251 0.025
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0042 0.0063 0.0062
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0197 0.0542 0.054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.0651 0.1837
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0024 0.0005 0.0004
Schistosoma mansoni tar DNA-binding protein 0.0225 0.0628 0.0626
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0052 0.0094 0.0093
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0045 0.0071 0.007
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0051 0.0092 0.0247
Trichomonas vaginalis CAMK family protein kinase 0.0036 0.0043 0.012
Toxoplasma gondii cathepsin CPC2 0.0232 0.0651 0.1828
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0154 0.0433
Echinococcus multilocularis cysteine protease 0.0845 0.2549 0.2548
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0197 0.0542 0.054
Loa Loa (eye worm) hypothetical protein 0.0249 0.0702 0.0701
Schistosoma mansoni sex comb on midleg homolog 0.008 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0232 0.0651 0.065
Plasmodium falciparum thioredoxin reductase 0.0027 0.0016 0.0046
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0027 0.0016 0.197
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0075 0.0165 0.0163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.024 0.0675 0.0674
Trypanosoma cruzi transcription factor btf3, putative 0.0026 0.0013 0.0013
Entamoeba histolytica cysteine proteinase, putative 0.0481 0.1421 0.4948
Loa Loa (eye worm) cathepsin B 0.1166 0.3542 0.3542
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1166 0.3542 1
Brugia malayi Papain family cysteine protease containing protein 0.0481 0.1421 0.1419
Echinococcus multilocularis lysine specific demethylase 5A 0.0089 0.0207 0.0205
Loa Loa (eye worm) hypothetical protein 0.0062 0.0123 0.0122
Loa Loa (eye worm) hypothetical protein 0.0032 0.0032 0.003
Brugia malayi MAP kinase sur-1 0.0051 0.0092 0.009
Schistosoma mansoni survival motor neuron protein 0.0051 0.009 0.0089
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0225 0.0628 0.0626
Entamoeba histolytica cysteine protease, putative 0.0232 0.0651 0.226
Loa Loa (eye worm) hypothetical protein 0.0082 0.0187 0.0186
Echinococcus granulosus snurportin 1 0.0231 0.0649 0.0648
Echinococcus granulosus cathepsin L cysteine proteinase 0.0845 0.2549 0.2548
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0092 0.0217 0.0216
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0073 0.0159 0.0158
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0042 0.0063 0.0063
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0044 0.0043
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0155 0.0414 0.0412
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0845 0.2549 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0195 0.0536 0.0535
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Echinococcus multilocularis lamin 0.0024 0.0006 0.0005
Entamoeba histolytica cysteine protease, putative 0.0232 0.0651 0.226
Onchocerca volvulus 0.003 0.0026 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0597 0.178 0.5024
Giardia lamblia Cathepsin L-like protease 0.0232 0.0651 0.1824
Brugia malayi hypothetical protein 0.0028 0.0018 0.0017
Trichomonas vaginalis chaperonin, putative 0.0024 0.0006 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0195 0.0536 0.0535
Brugia malayi nuclear hormone receptor 0.0195 0.0536 0.0535
Trichomonas vaginalis alpha-glucosidase, putative 0.0045 0.0071 0.0199
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0845 0.2549 0.2548
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Echinococcus granulosus mitogen activated protein kinase 0.0051 0.0092 0.009
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0092 0.0092
Trichomonas vaginalis glutaminase, putative 0.0206 0.0569 0.1604
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0195 0.0536 0.0535
Onchocerca volvulus 0.0845 0.2549 1
Schistosoma mansoni tar DNA-binding protein 0.0225 0.0628 0.0626
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0027 0.0016 0.0014
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0027 0.0016 0.0046
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0062 0.0123 0.0877
Plasmodium vivax unspecified product 0.0481 0.1421 0.5565
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0232 0.0651 0.226
Echinococcus multilocularis lamin dm0 0.0024 0.0006 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0195 0.0536 0.0535
Plasmodium falciparum serine repeat antigen 7 0.0232 0.0651 0.2542
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0155 0.0414 0.0412
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0037 0.0105
Toxoplasma gondii preprocathepsin c precursor, putative 0.0232 0.0651 0.1828
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0195 0.0536 0.0535
Brugia malayi photoreceptor-specific nuclear receptor 0.0195 0.0536 0.0535
Loa Loa (eye worm) hypothetical protein 0.0504 0.1494 0.1493
Echinococcus multilocularis cathepsin L 0.0481 0.1421 0.1419
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0069 0.0246
Brugia malayi Papain family cysteine protease containing protein 0.0232 0.0651 0.065
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Loa Loa (eye worm) hypothetical protein 0.0232 0.0651 0.065
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0232 0.0651 0.1837
Schistosoma mansoni hypothetical protein 0.0073 0.0159 0.0158
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Schistosoma mansoni tsg101-related 0.0036 0.0042 0.0041
Schistosoma mansoni hypothetical protein 0.0176 0.0478 0.0477
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0119 0.0842
Echinococcus multilocularis serine protein kinase ATM 0.003 0.0025 0.0024
Leishmania major cathepsin L-like protease 0.0957 0.2894 0.817
Echinococcus multilocularis transcription factor btf3 0.0026 0.0013 0.0012
Trypanosoma cruzi cysteine proteinase, putative 0.0481 0.1421 0.1421
Brugia malayi jmjC domain containing protein 0.0099 0.0239 0.0237
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.003 0.0025 0.0055
Plasmodium falciparum ataxin-2 like protein, putative 0.0043 0.0065 0.0239
Leishmania major cathepsin L-like protease 0.0957 0.2894 0.817
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1166 0.3542 1
Entamoeba histolytica cysteine protease, putative 0.0232 0.0651 0.226
Plasmodium vivax hypothetical protein, conserved 0.0062 0.0123 0.0469
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Brugia malayi MH2 domain containing protein 0.0393 0.1149 0.1148
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0092 0.0258
Loa Loa (eye worm) MBCTL1 0.0091 0.0214 0.0212
Loa Loa (eye worm) hypothetical protein 0.0249 0.0702 0.0701
Echinococcus multilocularis Smad4 0.0027 0.0015 0.0014
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0232 0.0651 0.2542
Brugia malayi cathepsin Z-like cysteine proteinase 0.0232 0.0651 0.065
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0355 0.1032 0.1031
Schistosoma mansoni smad 0.0027 0.0015 0.0014
Loa Loa (eye worm) MH1 domain-containing protein 0.0027 0.0015 0.0014
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0355 0.1032 0.1031
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0195 0.0536 0.0535
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0232 0.0651 0.065
Brugia malayi Cathepsin L-like precursor 0.0845 0.2549 0.2548
Onchocerca volvulus 0.0092 0.0217 0.0829
Schistosoma mansoni tyrosine kinase 0.0598 0.1782 0.1781
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0024 0.0005 0.0004
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0051 0.0092 0.0258
Brugia malayi Papain family cysteine protease containing protein 0.0232 0.0651 0.065
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0028 0.0018 0.0102
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0024 0.0006 0.0007
Onchocerca volvulus 0.0621 0.1853 0.7264
Brugia malayi ecdysteroid receptor 0.0195 0.0536 0.0535
Trypanosoma cruzi ISWI complex protein 0.0038 0.0051 0.0051
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0051 0.0092 0.0258
Mycobacterium tuberculosis Probable hydrolase 0.0062 0.0123 0.0877
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.003 0.0025 0.006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0062 0.0123 0.0122
Onchocerca volvulus 0.0062 0.0123 0.0461
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.003 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0103 0.0251 0.025
Loa Loa (eye worm) bromodomain containing protein 0.0044 0.007 0.0068
Loa Loa (eye worm) hypothetical protein 0.0103 0.0251 0.025
Echinococcus multilocularis JmjC domain containing protein 4 0.0024 0.0005 0.0004
Schistosoma mansoni hypothetical protein 0.0024 0.0006 0.0005
Leishmania major basic transcription factor 3a, putative 0.0026 0.0013 0.0038
Mycobacterium tuberculosis Probable reductase 0.0177 0.0482 0.3507
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0053 0.0096 0.0354
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Trichomonas vaginalis D-aminoacylase, putative 0.0062 0.0123 0.0348
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1166 0.3542 0.3542
Onchocerca volvulus Alhambra homolog 0.0073 0.0159 0.0601
Brugia malayi Smad1 0.0027 0.0015 0.0014
Echinococcus multilocularis inositol monophosphatase 1 0.0028 0.0018 0.0017
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0042 0.0063 0.0233
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Schistosoma mansoni polycystin 1-related 0.003 0.0026 0.0024
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0232 0.0651 0.2542
Echinococcus multilocularis lipoxygenase domain containing protein 0.003 0.0026 0.0024
Loa Loa (eye worm) hypothetical protein 0.0597 0.178 0.1779
Loa Loa (eye worm) hypothetical protein 0.0195 0.0536 0.0535
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0037 0.0105
Echinococcus multilocularis peregrin 0.0079 0.0177 0.0176
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0092 0.0217 0.0216
Brugia malayi hypothetical protein 0.0053 0.0096 0.0095
Schistosoma mansoni lozenge 0.0042 0.0062 0.006
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0845 0.2549 0.2548
Giardia lamblia Cathepsin L precursor 0.0232 0.0651 0.1824
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0232 0.0651 0.065
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Mycobacterium ulcerans hypothetical protein 0.0062 0.0123 0.0877
Schistosoma mansoni inositol monophosphatase 0.0028 0.0018 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0096 0.0271
Schistosoma mansoni steroid hormone receptor ad4bp 0.0195 0.0536 0.0535
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Echinococcus multilocularis nuclear receptor nhr 48 0.0092 0.0217 0.0216
Schistosoma mansoni hypothetical protein 0.0176 0.0478 0.0477
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0232 0.0651 0.065
Brugia malayi conserved hypotetical protein 0.0092 0.0217 0.0216
Loa Loa (eye worm) MH2 domain-containing protein 0.0393 0.1149 0.1148
Trichomonas vaginalis glucosylceramidase, putative 0.019 0.0521 0.147
Trichomonas vaginalis CAMK family protein kinase 0.0071 0.0154 0.0433
Loa Loa (eye worm) hypothetical protein 0.0062 0.0123 0.0122
Echinococcus granulosus lipoxygenase domain containing protein 0.003 0.0026 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0275 0.0784 0.2212
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0092 0.0217 0.0829
Entamoeba histolytica transcription factor BTF3, putative 0.0026 0.0013 0.0033
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0092 0.0217 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.0651 0.1837
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0071 0.0154 0.0152
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0005 0.0004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0092 0.0217 0.0216
Mycobacterium tuberculosis Probable lipase LipE 0.0062 0.0123 0.0877
Loa Loa (eye worm) hypothetical protein 0.0062 0.0123 0.0122
Schistosoma mansoni transcription factor btf3 0.0026 0.0013 0.0012
Loa Loa (eye worm) nuclear receptor NHR-67 0.0092 0.0217 0.0216
Entamoeba histolytica cysteine proteinase, putative 0.0481 0.1421 0.4948
Echinococcus granulosus GPCR family 2 0.0176 0.0478 0.0477
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0027 0.0016 0.0014
Schistosoma mansoni sex comb on midleg homolog 0.008 0.0179 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.025 0.0705 0.0704
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0558 0.1658 0.1657
Schistosoma mansoni cathepsin F (C01 family) 0.0845 0.2549 0.2548
Brugia malayi Nuclear hormone receptor E75 0.0092 0.0217 0.0216
Schistosoma mansoni jumonji/arid domain-containing protein 0.0099 0.0239 0.0237
Toxoplasma gondii t-complex protein beta subunit 0.0024 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0103 0.0251 0.025
Echinococcus multilocularis histone acetyltransferase MYST2 0.0091 0.0214 0.0212
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Loa Loa (eye worm) hypothetical protein 0.0091 0.0214 0.0212
Plasmodium falciparum serine repeat antigen 5 0.0232 0.0651 0.2542
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0046 0.0074 0.0208
Mycobacterium ulcerans arylsulfatase AtsD 0.0053 0.0096 0.0677
Plasmodium falciparum serine repeat antigen 2 0.0232 0.0651 0.2542
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0948 0.2867 0.8093
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0025 0.0071
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.003 0.0025 0.0074
Echinococcus multilocularis SAM and MBT domain containing protein 0.008 0.0179 0.0178
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0232 0.0651 0.2542
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0091 0.0214 0.0212
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0481 0.1421 0.401
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0059 0.0166
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0051 0.0092 0.0092
Schistosoma mansoni tyrosine kinase 0.1112 0.3375 0.3374
Schistosoma mansoni alpha-glucosidase 0.0174 0.0469 0.0468
Mycobacterium tuberculosis Possible hydrolase 0.0053 0.0096 0.0677
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0123 0.0313 0.0311
Brugia malayi cathepsin F-like cysteine proteinase 0.0249 0.0702 0.0701
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0028 0.0018 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0957 0.2894 0.8168
Schistosoma mansoni thyroid hormone receptor 0.0195 0.0536 0.0535
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0232 0.0651 0.2542
Echinococcus granulosus neutral alpha glucosidase AB 0.0045 0.0071 0.007
Brugia malayi hypothetical protein 0.0103 0.0251 0.025
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0232 0.0651 0.1824
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0119 0.0842
Loa Loa (eye worm) CXXC zinc finger family protein 0.0097 0.0232 0.0231
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0232 0.0651 0.065
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Trypanosoma cruzi cruzipain precursor, putative 0.0957 0.2894 0.2894
Brugia malayi Protein kinase domain containing protein 0.0355 0.1032 0.1031
Loa Loa (eye worm) hypothetical protein 0.0092 0.0217 0.0216
Leishmania major cathepsin L-like protease 0.0957 0.2894 0.817
Toxoplasma gondii histone lysine methyltransferase SET1 0.0192 0.0528 0.1479
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0195 0.0536 0.0535
Brugia malayi hypothetical protein 0.0103 0.0251 0.025
Plasmodium falciparum thioredoxin reductase 0.0078 0.0173 0.0664
Loa Loa (eye worm) glutathione reductase 0.0078 0.0173 0.0172
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0491 0.1385
Echinococcus multilocularis cathepsin L cysteine protease 0.0845 0.2549 0.2548
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0481 0.1421 0.401
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.009 0.0089
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.3252 1 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0024 0.0005 0.0005
Echinococcus multilocularis smad 0.0027 0.0015 0.0014
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0232 0.0651 0.2542
Plasmodium falciparum basic transcription factor 3b, putative 0.0026 0.0013 0.0037
Leishmania major hypothetical protein, conserved 0.0024 0.0005 0.0015
Echinococcus multilocularis beta LACTamase domain containing family member 0.0062 0.0123 0.0122
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0159 0.0609
Schistosoma mansoni phosphatidylserine receptor 0.0024 0.0005 0.0004
Brugia malayi hypothetical protein 0.1774 0.5425 0.5424
Brugia malayi Papain family cysteine protease containing protein 0.0481 0.1421 0.1419
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0119 0.0324
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0195 0.0536 0.0535
Schistosoma mansoni hypothetical protein 0.061 0.182 0.1819
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0131 0.0339 0.0338
Loa Loa (eye worm) histone methyltransferase 0.0033 0.0034 0.0033
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0195 0.0536 0.0535
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0195 0.0536 0.0535
Echinococcus granulosus RUN 0.003 0.0026 0.0024
Loa Loa (eye worm) hypothetical protein 0.0062 0.0123 0.0122
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0027 0.0016 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0042 0.0063 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0177 0.0482 0.3507
Schistosoma mansoni cathepsin B (C01 family) 0.0232 0.0651 0.065
Giardia lamblia Cathepsin L-like protease 0.0232 0.0651 0.1824
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0025 0.007
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0004 0.0011
Onchocerca volvulus 0.0051 0.009 0.0329
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0024 0.0006 0.0005
Brugia malayi hypothetical protein 0.0333 0.0963 0.0962
Leishmania major cathepsin L-like protease 0.0845 0.2549 0.7196
Schistosoma mansoni zinc finger protein 0.0038 0.0051 0.005
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0195 0.0536 0.0535
Brugia malayi glutaminase DH11.1 0.0206 0.0569 0.0567
Loa Loa (eye worm) hypothetical protein 0.0178 0.0482 0.0481
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0091 0.0214 0.0212
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0195 0.0536 0.0535
Loa Loa (eye worm) hypothetical protein 0.0232 0.0651 0.065
Leishmania major hypothetical protein, conserved 0.0062 0.0123 0.0349
Onchocerca volvulus 0.0062 0.0123 0.0461
Echinococcus multilocularis Protein lozenge 0.0042 0.0062 0.006
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0027 0.0016 0.0014
Trichomonas vaginalis chromobox protein, putative 0.0073 0.0159 0.0447
Brugia malayi Nuclear hormone receptor-like 1 0.0103 0.0251 0.025
Entamoeba histolytica hypothetical protein 0.003 0.0025 0.0074
Schistosoma mansoni zinc finger protein 0.0055 0.0102 0.01
Brugia malayi hypothetical protein 0.0052 0.0094 0.0093
Onchocerca volvulus 0.0082 0.0187 0.0713
Giardia lamblia Fructose-bisphosphate aldolase 0.0948 0.2867 0.8089
Giardia lamblia Kinase, PLK 0.0071 0.0154 0.0417
Schistosoma mansoni tyrosine kinase 0.0598 0.1782 0.1781
Loa Loa (eye worm) hypothetical protein 0.0103 0.0251 0.025
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0053 0.0096 0.0677
Toxoplasma gondii NADPH-glutathione reductase 0.0027 0.0016 0.0033
Schistosoma mansoni cathepsin C 0.0232 0.0651 0.065
Entamoeba histolytica cysteine protease, putative 0.0481 0.1421 0.4948
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0053 0.0096 0.0271
Echinococcus granulosus lamin 0.0024 0.0006 0.0005
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0027 0.0016 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0845 0.2549 0.7196
Brugia malayi Pre-SET motif family protein 0.0546 0.1621 0.162
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0845 0.2549 0.7196
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0092 0.0217 0.0829
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0195 0.0536 0.0535
Echinococcus granulosus lysine specific demethylase 6a 0.0024 0.0005 0.0004
Mycobacterium tuberculosis Conserved protein 0.0062 0.0123 0.0877
Loa Loa (eye worm) glutaminase 0.0206 0.0569 0.0567
Onchocerca volvulus Cathepsin L homolog 0.0232 0.0651 0.2535
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0071 0.0071
Leishmania major alpha glucosidase II subunit, putative 0.0045 0.0071 0.02
Giardia lamblia NADH oxidase lateral transfer candidate 0.0027 0.0016 0.0028
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0027 0.0016 0.0046
Echinococcus multilocularis thyroid hormone receptor alpha 0.0195 0.0536 0.0535
Echinococcus multilocularis 0.0344 0.0998 0.0997
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0052 0.0094 0.0093

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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