Detailed information for compound 905906

Basic information

Technical information
  • TDR Targets ID: 905906
  • Name: N-[(4-chlorophenyl)methylideneamino]-2-phenyl quinoline-4-carboxamide
  • MW: 385.846 | Formula: C23H16ClN3O
  • H donors: 1 H acceptors: 2 LogP: 5.39 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)C=NNC(=O)c1cc(nc2c1cccc2)c1ccccc1
  • InChi: 1S/C23H16ClN3O/c24-18-12-10-16(11-13-18)15-25-27-23(28)20-14-22(17-6-2-1-3-7-17)26-21-9-5-4-8-19(20)21/h1-15H,(H,27,28)/b25-15+
  • InChiKey: DDOJVMQCMWJWBI-MFKUBSTISA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[(4-chlorophenyl)methyleneamino]-2-phenyl-quinoline-4-carboxamide
  • N-[(4-chlorophenyl)methyleneamino]-2-phenyl-4-quinolinecarboxamide
  • N-[(4-chlorobenzylidene)amino]-2-phenyl-cinchoninamide
  • N-[(4-chlorophenyl)methylideneamino]-2-phenyl-quinoline-4-carboxamide
  • 6956-51-0
  • ZINC01692330
  • ST5045921
  • NSC65046

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0556 0.0556
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0109 0.3137 1
Entamoeba histolytica cysteine protease, putative 0.0034 0.0615 0.4054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.1422 0.3201
Echinococcus multilocularis cathepsin L cysteine protease 0.0058 0.1422 0.1367
Entamoeba histolytica cysteine protease, putative 0.0034 0.0615 0.4054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.1422 0.1664
Loa Loa (eye worm) cysteine protease 0.0058 0.1422 0.1422
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0109 0.3137 0.3137
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.1575 0.5
Onchocerca volvulus 0.0042 0.0871 0.0989
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0064 0.0064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.1422 0.1664
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0556 0.0495
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.1144 0.1087
Brugia malayi Cathepsin L-like precursor 0.0058 0.1422 0.1422
Entamoeba histolytica cysteine protease, putative 0.0058 0.1422 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.1422 0.1664
Trichomonas vaginalis set domain proteins, putative 0.0258 0.8226 1
Echinococcus granulosus cathepsin L cysteine protease 0.0034 0.0615 0.0554
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0064 0.0064
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0064 0.0064
Echinococcus granulosus cathepsin b 0.0311 1 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0311 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.1422 0.1664
Onchocerca volvulus 0.0058 0.1422 0.1664
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0018 0.0064 0.0064
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0018 0.0064 0.0451
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0034 0.0615 0.0615
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0064 0.0064
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.1144 0.1087
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0018 0.0064 0.0451
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.1422 0.1664
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0227 0.7161 0.7161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0871 0.0989
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0311 1 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0064 0.0064
Brugia malayi cathepsin L-like precursor 0.0042 0.0871 0.0871
Trypanosoma cruzi cysteine peptidase, putative 0.0034 0.0615 0.0615
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0018 0.0064 0.0451
Onchocerca volvulus 0.0058 0.1422 0.1664
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0034 0.0615 0.0615
Brugia malayi fibroinase precursor 0.0018 0.0064 0.0064
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0556 0.0556
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0615 0.4054
Onchocerca volvulus 0.0058 0.1422 0.1664
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0064 0.0064
Echinococcus multilocularis cathepsin b 0.0311 1 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0064 0.0064
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0058 0.1422 1
Trypanosoma cruzi cysteine proteinase, putative 0.0034 0.0615 0.0615
Entamoeba histolytica cysteine proteinase 2 0.0034 0.0615 0.4054
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0109 0.3137 0.3137
Brugia malayi Cathepsin L-like precursor 0.0058 0.1422 0.1422
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.1422 0.1664
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0058 0.1422 0.1664
Loa Loa (eye worm) hypothetical protein 0.0018 0.0064 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.1422 0.3201
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0063 0.1575 0.0892
Plasmodium vivax vivapain-2 0.0058 0.1422 1
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0064 0.0451
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.1144 0.1144
Onchocerca volvulus Cathepsin F homolog 0.0058 0.1422 0.1664
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0615 0.0674
Plasmodium falciparum cysteine proteinase falcipain 3 0.0058 0.1422 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.1422 0.1422
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0615 0.4054
Plasmodium vivax vivapain-1 0.0034 0.0615 0.4322
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.1422 0.1664
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.1422 0.1664
Plasmodium vivax vivapain-2 0.0058 0.1422 1
Trypanosoma cruzi cysteine proteinase, putative 0.0034 0.0615 0.0615
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.1575 0.5
Onchocerca volvulus Cathepsin L homolog 0.0058 0.1422 0.1664
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.1422 0.1422
Brugia malayi Cathepsin L-like precursor 0.0058 0.1422 0.1422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0615 0.0674
Entamoeba histolytica cysteine proteinase, putative 0.0058 0.1422 1
Echinococcus granulosus cathepsin b 0.0311 1 1
Echinococcus multilocularis cathepsin L 0.0034 0.0615 0.0554
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.1575 0.1521
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.1422 0.3201
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0064 0.0064
Entamoeba histolytica cysteine proteinase 1, putative 0.0034 0.0615 0.4054
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.1144 0.1144
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0058 0.1422 0.1367
Schistosoma mansoni cathepsin F (C01 family) 0.0058 0.1422 0.1422
Toxoplasma gondii cathepsin CPL 0.0058 0.1422 0.4419
Schistosoma mansoni cathepsin C 0.0018 0.0064 0.0064
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0063 0.1575 0.1575
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0064 0.0064
Echinococcus granulosus cathepsin l1 0.0058 0.1422 0.1367
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0615 0.4054
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0615 0.0615
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.1422 0.3201
Brugia malayi Papain family cysteine protease containing protein 0.0058 0.1422 0.1422
Brugia malayi Cathepsin L-like precursor 0.0058 0.1422 0.1422
Echinococcus multilocularis cysteine protease 0.0058 0.1422 0.1367
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0018 0.0064 0.0451
Echinococcus granulosus cathepsin l1 0.0042 0.0871 0.0813
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0058 0.1422 0.1422
Entamoeba histolytica cysteine protease, putative 0.0034 0.0615 0.4054
Echinococcus granulosus cathepsin L cysteine proteinase 0.0058 0.1422 0.1367
Brugia malayi Cathepsin L-like precursor 0.0058 0.1422 0.1422
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.1422 0.3201
Loa Loa (eye worm) hypothetical protein 0.0018 0.0064 0.0064
Entamoeba histolytica cysteine protease, putative 0.0034 0.0615 0.4054
Loa Loa (eye worm) hypothetical protein 0.0033 0.0556 0.0556
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.1422 0.3201
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0042 0.0871 0.0989
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0064 0.0064
Onchocerca volvulus 0.0058 0.1422 0.1664
Onchocerca volvulus 0.0058 0.1422 0.1664
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0034 0.0615 0.0615
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0058 0.1422 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0556 0.1599
Toxoplasma gondii cathepsin B 0.0109 0.3137 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.1144 0.1144
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.1422 0.3201
Entamoeba histolytica cysteine protease, putative 0.0034 0.0615 0.4054
Onchocerca volvulus Cathepsin L homolog 0.0058 0.1422 0.1664
Brugia malayi Cathepsin L-like precursor 0.0042 0.0871 0.0871
Loa Loa (eye worm) hypothetical protein 0.0042 0.0871 0.0871
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0018 0.0064 0.0451
Entamoeba histolytica cysteine protease, putative 0.0034 0.0615 0.4054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.1422 0.1664
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0058 0.1422 0.1367
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0556 0.0556
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0556 0.0556
Plasmodium vivax unspecified product 0.0018 0.0064 0.0451
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.1422 0.1664
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0058 0.1422 0.1422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.1422 0.1664
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0064 0.0064
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0064 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.1422 0.3201
Entamoeba histolytica cysteine protease, putative 0.0034 0.0615 0.4054
Entamoeba histolytica cysteine protease, putative 0.0034 0.0615 0.4054
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0042 0.0871 0.0871
Giardia lamblia Cathepsin B precursor 0.0109 0.3137 1
Brugia malayi Pre-SET motif family protein 0.0227 0.7161 0.7161
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.3873 0.3873
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.1422 0.1664
Trypanosoma cruzi cruzipain precursor, putative 0.0058 0.1422 0.1422
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.1144 0.1087
Entamoeba histolytica cysteine protease, putative 0.0034 0.0615 0.4054
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0063 0.1575 0.1575
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.1432 0.1432
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0556 0.0495
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0064 0.0064
Loa Loa (eye worm) transcription factor SMAD2 0.013 0.3873 0.3873
Brugia malayi Cathepsin L-like precursor 0.0042 0.0871 0.0871
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0064 0.0064
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0064 0.0064
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0064 0.0451
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0064 0.0064
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0018 0.0064 0.0451
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0064 0.0064
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0064 0.0451
Plasmodium vivax vivapain-3 0.0034 0.0615 0.4322
Entamoeba histolytica cysteine proteinase, putative 0.0042 0.0871 0.5946
Echinococcus granulosus cathepsin L 0.0034 0.0615 0.0554
Entamoeba histolytica cysteine proteinase, putative 0.0058 0.1422 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0064 0.0064
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0018 0.0064 0.0451
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.1144 0.1144
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.1575 0.1521
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.1422 0.1664
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.1422 0.1664
Onchocerca volvulus 0.0058 0.1422 0.1664
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.1422 0.3201
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0034 0.0615 0.0615
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0064 0.0064
Trypanosoma cruzi cysteine protease, putative 0.0034 0.0615 0.0615
Loa Loa (eye worm) hypothetical protein 0.0018 0.0064 0.0064
Echinococcus granulosus cysteine protease 0.0034 0.0615 0.0554
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.1422 0.1664
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0311 1 1
Giardia lamblia Cathepsin B precursor 0.0109 0.3137 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0311 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.1422 0.1664
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.1422 0.3201
Entamoeba histolytica cysteine protease, putative 0.0034 0.0615 0.4054
Onchocerca volvulus 0.0033 0.0556 0.0602
Loa Loa (eye worm) ctsf protein 0.0058 0.1422 0.1422
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.1422 0.1664
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0064 0.0064
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.1144 0.1144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.1422 0.1664
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0064 0.0064
Onchocerca volvulus 0.0058 0.1422 0.1664
Onchocerca volvulus 0.0258 0.8226 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0058 0.1422 0.1664
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0515 0.0454
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.0615 0.0615
Schistosoma mansoni cathepsin F (C01 family) 0.0058 0.1422 0.1422
Entamoeba histolytica cysteine protease, putative 0.0034 0.0615 0.4054
Echinococcus multilocularis cathepsin L cysteine protease 0.0058 0.1422 0.1367
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0556 0.0495
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0615 0.4054
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.1144 0.1087
Brugia malayi Cathepsin L-like cysteine proteinase 0.0042 0.0871 0.0871
Entamoeba histolytica cysteine protease, putative 0.0034 0.0615 0.4054
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0063 0.1575 0.5
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.1422 0.1664
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0311 1 1
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0064 0.0064
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0064 0.0064
Echinococcus multilocularis cathepsin b 0.0311 1 1
Brugia malayi cathepsin L precursor 0.0018 0.0064 0.0064
Echinococcus granulosus cathepsin l cysteine peptidase 0.0058 0.1422 0.1367
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.1422 0.1422
Echinococcus multilocularis cysteine protease 0.0058 0.1422 0.1367
Entamoeba histolytica cysteine protease, putative 0.0034 0.0615 0.4054
Loa Loa (eye worm) cathepsin B 0.0109 0.3137 0.3137
Brugia malayi MH2 domain containing protein 0.013 0.3873 0.3873
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0018 0.0064 0.0451
Trypanosoma brucei cysteine peptidase C (CPC) 0.0109 0.3137 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0871 0.0871
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.1422 0.3201
Brugia malayi Pre-SET motif family protein 0.0033 0.0556 0.0556
Schistosoma mansoni cathepsin F (C01 family) 0.0042 0.0871 0.0871
Giardia lamblia Cathepsin B precursor 0.0109 0.3137 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0064 0.0451
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0109 0.3137 0.3765
Brugia malayi Cathepsin L-like precursor 0.0058 0.1422 0.1422
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0064 0.0064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.1422 0.1664
Loa Loa (eye worm) fibroinase 0.0058 0.1422 0.1422
Plasmodium vivax unspecified product 0.0034 0.0615 0.4322
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.1422 0.1664
Loa Loa (eye worm) hypothetical protein 0.0042 0.0871 0.0871
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0058 0.1422 0.1664
Plasmodium vivax SET domain protein, putative 0.0033 0.0556 0.3907
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0058 0.1422 0.1664
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.1422 0.1422
Plasmodium falciparum cysteine proteinase falcipain 1 0.0034 0.0615 0.4054
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0311 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.1422 0.1422

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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