Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PROBABLE CYTOCHROME C OXIDASE POLYPEPTIDE I CTAD (CYTOCHROME AA3 SUBUNIT 1) | 0.0167 | 0.2692 | 1 |
Schistosoma mansoni | cytochrome c oxidase subunit II | 0.0383 | 0.7936 | 1 |
Schistosoma mansoni | cytochrome-c oxidase | 0.0141 | 0.2064 | 0.2318 |
Wolbachia endosymbiont of Brugia malayi | cytochrome c oxidase, subunit 2 | 0.0467 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0308 | 0.6126 | 0.7632 |
Loa Loa (eye worm) | cytochrome oxidase subunit 2 | 0.0085 | 0.0689 | 0.1124 |
Brugia malayi | Animal haem peroxidase family protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0308 | 0.6126 | 1 |
Schistosoma mansoni | cytochrome oxidase subunit | 0.0167 | 0.2692 | 0.314 |
Onchocerca volvulus | 0.0308 | 0.6126 | 1 | |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0308 | 0.6126 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0308 | 0.6126 | 1 |
Schistosoma mansoni | peroxidasin | 0.0308 | 0.6126 | 0.7632 |
Brugia malayi | Animal haem peroxidase family protein | 0.0308 | 0.6126 | 1 |
Schistosoma mansoni | cytochrome oxidase subunit | 0.0167 | 0.2692 | 0.314 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0308 | 0.6126 | 1 |
Brugia malayi | cytochrome c oxidase subunit I | 0.0068 | 0.0292 | 0.0476 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0308 | 0.6126 | 1 |
Mycobacterium ulcerans | cytochrome C oxidase polypeptide I CtaD | 0.0167 | 0.2692 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Onchocerca volvulus | 0.0308 | 0.6126 | 1 | |
Onchocerca volvulus | Dual oxidase homolog | 0.0308 | 0.6126 | 1 |
Toxoplasma gondii | cytochrome C oxidase subunit IIb, putative | 0.0141 | 0.2064 | 0.5 |
Plasmodium falciparum | cytochrome c oxidase subunit 1 | 0.0167 | 0.2692 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | cytochrome c oxidase subunit I | 0.0068 | 0.0292 | 0.0476 |
Schistosoma mansoni | cytochrome oxidase subunit | 0.0167 | 0.2692 | 0.314 |
Brugia malayi | Peroxidasin | 0.0308 | 0.6126 | 1 |
Brugia malayi | hypothetical protein | 0.0308 | 0.6126 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0308 | 0.6126 | 1 |
Plasmodium vivax | cytochrome c oxidase subunit I | 0.0167 | 0.2692 | 0.1398 |
Brugia malayi | Animal haem peroxidase family protein | 0.0308 | 0.6126 | 1 |
Mycobacterium ulcerans | cytochrome C oxidase polypeptide I CtaD | 0.0167 | 0.2692 | 1 |
Plasmodium vivax | conserved Plasmodium protein, unknown function | 0.0326 | 0.6561 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0308 | 0.6126 | 1 |
Echinococcus granulosus | peroxidasin | 0.0308 | 0.6126 | 0.4699 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Onchocerca volvulus | Cytochrome c oxidase subunit 1 homolog | 0.0167 | 0.2692 | 0.1547 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Schistosoma mansoni | cytochrome oxidase subunit | 0.0167 | 0.2692 | 0.314 |
Onchocerca volvulus | 0.0308 | 0.6126 | 1 | |
Echinococcus multilocularis | peroxidasin | 0.0308 | 0.6126 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Mycobacterium tuberculosis | Probable cytochrome C oxidase polypeptide I CtaD (cytochrome AA3 subunit 1) | 0.0167 | 0.2692 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0308 | 0.6126 | 1 |
Onchocerca volvulus | 0.0167 | 0.2692 | 0.1547 | |
Onchocerca volvulus | Peroxidase homolog | 0.0308 | 0.6126 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.6126 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.