Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | zinc-containing alcohol dehydrogenase NAD-dependent AdhB | 0.0943 | 1 | 1 |
Mycobacterium ulcerans | dehydrogenase | 0.014 | 0.0594 | 0.0594 |
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase, putative | 0.014 | 0.0594 | 0.5 |
Mycobacterium ulcerans | zinc-dependent alcohol dehydrogenase AdhE2 | 0.0943 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase FadB5 | 0.014 | 0.0594 | 0.0594 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0594 | 0.0594 |
Schistosoma mansoni | alcohol dehydrogenase | 0.0943 | 1 | 1 |
Mycobacterium ulcerans | NADP-dependent alcohol dehydrogenase Adh | 0.014 | 0.0594 | 0.0594 |
Trypanosoma brucei | oxidoreductase, putative | 0.014 | 0.0594 | 1 |
Mycobacterium leprae | Probable S-nitrosomycothiol reductase MscR | 0.0943 | 1 | 1 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.014 | 0.0594 | 1 |
Trypanosoma cruzi | oxidoreductase, putative | 0.014 | 0.0594 | 1 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.014 | 0.0594 | 1 |
Mycobacterium tuberculosis | Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) | 0.0943 | 1 | 1 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.014 | 0.0594 | 0.0594 |
Mycobacterium ulcerans | zinc-type alcohol dehydrogenase AdhD | 0.0943 | 1 | 1 |
Trypanosoma brucei | oxidoreductase, putative | 0.014 | 0.0594 | 1 |
Echinococcus granulosus | mitochondrial trans 2 enoyl coenzyme A reductase | 0.014 | 0.0594 | 0.5 |
Trypanosoma cruzi | nuclear receptor binding factor, putative | 0.014 | 0.0594 | 1 |
Mycobacterium tuberculosis | Possible zinc-containing alcohol dehydrogenase NAD dependent AdhB | 0.0804 | 0.8367 | 0.8264 |
Leishmania major | NADP-dependent alcohol dehydrogenase, putative | 0.014 | 0.0594 | 1 |
Mycobacterium ulcerans | polyketide synthase | 0.014 | 0.0594 | 0.0594 |
Trypanosoma cruzi | nuclear receptor binding factor, putative | 0.014 | 0.0594 | 1 |
Leishmania major | oxidoreductase, putative | 0.014 | 0.0594 | 1 |
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase | 0.014 | 0.0594 | 0.5 |
Mycobacterium ulcerans | zinc-containing alcohol dehydrogenase NAD dependent AdhB | 0.0943 | 1 | 1 |
Echinococcus multilocularis | mitochondrial trans 2 enoyl coenzyme A reductase | 0.014 | 0.0594 | 0.5 |
Leishmania major | d-xylulose reductase, putative | 0.014 | 0.0594 | 1 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.014 | 0.0594 | 1 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.014 | 0.0594 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0594 | 0.0594 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.014 | 0.0594 | 0.5 |
Mycobacterium ulcerans | Zn-dependent alcohol dehydrogenase, AdhX | 0.014 | 0.0594 | 0.0594 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.014 | 0.0594 | 0.0594 |
Wolbachia endosymbiont of Brugia malayi | NADPH:quinone reductase | 0.014 | 0.0594 | 0.5 |
Mycobacterium ulcerans | quinone oxidoreductase | 0.014 | 0.0594 | 0.0594 |
Mycobacterium ulcerans | NADP-dependent alcohol dehydrogenase AdhC | 0.014 | 0.0594 | 0.0594 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.014 | 0.0594 | 0.0594 |
Mycobacterium ulcerans | NADPH quinone oxidoreductase FadB4 | 0.014 | 0.0594 | 0.0594 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.014 | 0.0594 | 0.0594 |
Leishmania major | quinone oxidoreductase, putative | 0.014 | 0.0594 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.014 | 0.0594 | 0.0594 |
Mycobacterium ulcerans | quinone oxidoreductase | 0.014 | 0.0594 | 0.0594 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.014 | 0.0594 | 0.5 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.014 | 0.0594 | 1 |
Leishmania major | oxidoreductase-like protein | 0.014 | 0.0594 | 1 |
Mycobacterium ulcerans | zinc-dependent alcohol dehydrogenase | 0.0943 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0594 | 0.0594 |
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase, putative | 0.014 | 0.0594 | 0.5 |
Mycobacterium tuberculosis | Probable zinc-type alcohol dehydrogenase (E subunit) AdhE1 | 0.0804 | 0.8367 | 0.8264 |
Onchocerca volvulus | 0.014 | 0.0594 | 0.0594 | |
Toxoplasma gondii | Zn-containing alcohol dehydrogenase | 0.0943 | 1 | 1 |
Onchocerca volvulus | Putative alcohol dehydrogenase | 0.0943 | 1 | 1 |
Leishmania major | zinc binding dehydrogenase-like protein | 0.014 | 0.0594 | 1 |
Mycobacterium ulcerans | quinone reductase Qor | 0.014 | 0.0594 | 0.0594 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.014 | 0.0594 | 0.0594 |
Loa Loa (eye worm) | alcohol dehydrogenase class III | 0.0943 | 1 | 1 |
Trypanosoma cruzi | oxidoreductase, putative | 0.014 | 0.0594 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.