TDR Targets

Basic information

Technical information

TDR Targets ID: 906760
Name: (4Z)-4-[(4-methylsulfanylphenyl)methylidene]- 2-phenyl-1,3-oxazol-5-one
MW: 295.356 | Formula: C17H13NO2S
H donors: 0 H acceptors: 1 LogP: 4.07 Rotable bonds: 3
Rule of 5 violations (Lipinski): 1
SMILES: CSc1ccc(cc1)C=C1N=C(OC1=O)c1ccccc1
InChi: 1S/C17H13NO2S/c1-21-14-9-7-12(8-10-14)11-15-17(19)20-16(18-15)13-5-3-2-4-6-13/h2-11H,1H3/b15-11-
InChiKey: PXCPXPCAXFUXPM-PTNGSMBKSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

(4Z)-4-[(4-methylsulfanylphenyl)methylene]-2-phenyl-oxazol-5-one
(4Z)-4-[[4-(methylthio)phenyl]methylene]-2-phenyl-5-oxazolone
(4Z)-4-[4-(methylthio)benzylidene]-2-phenyl-oxazol-5-one
ZINC00100672

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Entamoeba histolytica	cysteine proteinase 2	0.0035	0.0554	0.4054
Giardia lamblia	Cathepsin B precursor	0.011	0.3093	1
Echinococcus granulosus	beta LACTamase domain containing family member	0.0035	0.0566	0.0566
Echinococcus multilocularis	cathepsin L cysteine protease	0.0059	0.1367	0.1367
Brugia malayi	Cathepsin L-like precursor	0.0059	0.1367	0.1367
Schistosoma mansoni	cathepsin F (C01 family)	0.0059	0.1367	0.1367
Mycobacterium ulcerans	esterase/lipase LipP	0.0035	0.0566	0.5
Entamoeba histolytica	cysteine proteinase, putative	0.0059	0.1367	1
Loa Loa (eye worm)	D-ets-4 DNA binding domain-containing protein	0.0074	0.1862	0.1862
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.011	0.3093	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.009	0.2405	0.2405
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.1367	0.4419
Trichomonas vaginalis	penicillin-binding protein, putative	0.0035	0.0566	0.1831
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0059	0.1367	0.3201
Trypanosoma cruzi	cysteine protease, putative	0.0035	0.0554	0.0554
Onchocerca volvulus		0.0035	0.0566	0.4142
Loa Loa (eye worm)	fli-1 protein	0.0223	0.6912	0.6912
Trypanosoma cruzi	hypothetical protein, conserved	0.0035	0.0566	0.0566
Trypanosoma cruzi	cysteine peptidase, putative	0.0059	0.1367	0.1367
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.1367	0.4419
Schistosoma mansoni	gabp alpha	0.0074	0.1862	0.1862
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0059	0.1367	0.4419
Echinococcus multilocularis	cysteine protease	0.0059	0.1367	0.1367
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0315	1	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0315	1	1
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0035	0.0554	0.0554
Echinococcus multilocularis	cathepsin L	0.0035	0.0554	0.0554
Entamoeba histolytica	cysteine protease, putative	0.0035	0.0554	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.1367	0.4419
Schistosoma mansoni	ets-related	0.0223	0.6912	0.6912
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0059	0.1367	0.3201
Brugia malayi	Papain family cysteine protease containing protein	0.0035	0.0554	0.0554
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0566	0.0566
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0813	0.0813
Plasmodium vivax	vivapain-2	0.0059	0.1367	1
Echinococcus granulosus	cathepsin b	0.0315	1	1
Onchocerca volvulus		0.0059	0.1367	1
Brugia malayi	Cathepsin L-like precursor	0.0042	0.0813	0.0813
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0813	0.0813
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0035	0.0554	0.1791
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0315	1	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0059	0.1367	0.1367
Brugia malayi	Papain family cysteine protease containing protein	0.0035	0.0554	0.0554
Plasmodium vivax	hypothetical protein, conserved	0.0035	0.0566	0.4142
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0059	0.1367	0.1367
Plasmodium vivax	unspecified product	0.0035	0.0554	0.4054
Toxoplasma gondii	cathepsin B	0.011	0.3093	1
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0059	0.1367	1
Loa Loa (eye worm)	cysteine protease	0.0059	0.1367	0.1367
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0566	0.0566
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0035	0.0554	0.4054
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0059	0.1367	0.4419
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.1367	0.4419
Onchocerca volvulus		0.0059	0.1367	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0813	0.0813
Trypanosoma cruzi	cysteine peptidase, putative	0.0059	0.1367	0.1367
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.009	0.2405	0.2405
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0059	0.1367	0.3201
Entamoeba histolytica	cysteine protease, putative	0.0035	0.0554	0.4054
Onchocerca volvulus		0.0059	0.1367	1
Brugia malayi	Cathepsin L-like precursor	0.0059	0.1367	0.1367
Echinococcus granulosus	cathepsin L cysteine protease	0.0035	0.0554	0.0554
Echinococcus granulosus	cathepsin L	0.0035	0.0554	0.0554
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0059	0.1367	0.4419
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.1367	0.4419
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0059	0.1367	0.1367
Trypanosoma cruzi	cysteine peptidase, putative	0.0059	0.1367	0.1367
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.009	0.2405	0.2405
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.1367	0.4419
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0042	0.0813	0.0813
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0059	0.1367	0.4419
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0059	0.1367	1
Schistosoma mansoni	cathepsin F (C01 family)	0.0042	0.0813	0.0813
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.009	0.2405	0.2405
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.1367	0.4419
Echinococcus granulosus	cathepsin b	0.0315	1	1
Entamoeba histolytica	cysteine proteinase, putative	0.0035	0.0554	0.4054
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0059	0.1367	0.3201
Loa Loa (eye worm)	ctsf protein	0.0059	0.1367	0.1367
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0566	0.0566
Mycobacterium ulcerans	hypothetical protein	0.0035	0.0566	0.5
Brugia malayi	Cathepsin L-like precursor	0.0059	0.1367	0.1367
Giardia lamblia	Cathepsin B precursor	0.011	0.3093	1
Toxoplasma gondii	ABC1 family protein	0.0035	0.0566	0.1831
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.1367	0.4419
Entamoeba histolytica	cysteine proteinase, putative	0.0035	0.0554	0.4054
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0059	0.1367	0.4419
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0042	0.0813	0.2627
Trypanosoma cruzi	hypothetical protein, conserved	0.0035	0.0566	0.0566
Toxoplasma gondii	cathepsin CPL	0.0059	0.1367	0.4419
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0059	0.1367	1
Onchocerca volvulus	Cathepsin F homolog	0.0059	0.1367	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.1367	0.4419
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0042	0.0813	0.0813
Brugia malayi	Cathepsin L-like precursor	0.0059	0.1367	0.1367
Echinococcus granulosus	cysteine protease	0.0035	0.0554	0.0554
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0059	0.1367	0.3201
Mycobacterium ulcerans	lipase LipD	0.0035	0.0566	0.5
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0059	0.1367	0.4419
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0059	0.1367	0.1367
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0035	0.0566	0.0566
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0566	0.0566
Leishmania major	cathepsin L-like protease	0.0059	0.1367	0.3168
Entamoeba histolytica	cysteine protease, putative	0.0059	0.1367	1
Loa Loa (eye worm)	cathepsin B	0.011	0.3093	0.3093
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0059	0.1367	0.3201
Echinococcus multilocularis	cathepsin L cysteine protease	0.0059	0.1367	0.1367
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0059	0.1367	0.4419
Brugia malayi	Cathepsin L-like precursor	0.0059	0.1367	0.1367
Trypanosoma brucei	hypothetical protein, conserved	0.0035	0.0566	0.0048
Plasmodium vivax	vivapain-3	0.0035	0.0554	0.4054
Brugia malayi	Cathepsin L-like precursor	0.0042	0.0813	0.0813
Leishmania major	cysteine peptidase A (CPA)	0.0059	0.1367	0.3168
Brugia malayi	Cathepsin L-like precursor	0.0059	0.1367	0.1367
Entamoeba histolytica	cysteine protease, putative	0.0035	0.0554	0.4054
Onchocerca volvulus		0.0059	0.1367	1
Entamoeba histolytica	cysteine protease, putative	0.0035	0.0554	0.4054
Onchocerca volvulus	Cathepsin L homolog	0.0059	0.1367	1
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0566	0.0566
Trichomonas vaginalis	D-aminoacylase, putative	0.0035	0.0566	0.1831
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.1367	0.4419
Entamoeba histolytica	cysteine protease, putative	0.0035	0.0554	0.4054
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0059	0.1367	0.1367
Mycobacterium leprae	Probable lipase LipE	0.0035	0.0566	0.5
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0059	0.1367	0.4419
Onchocerca volvulus	Cathepsin L homolog	0.0059	0.1367	1
Entamoeba histolytica	cysteine proteinase, putative	0.0042	0.0813	0.5946
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0035	0.0566	0.0566
Onchocerca volvulus		0.0042	0.0813	0.5946
Giardia lamblia	Cathepsin B precursor	0.011	0.3093	1
Trichomonas vaginalis	penicillin-binding protein, putative	0.0035	0.0566	0.1831
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0059	0.1367	0.3201
Entamoeba histolytica	cysteine protease, putative	0.0035	0.0554	0.4054
Brugia malayi	Fli-1 protein	0.0223	0.6912	0.6912
Schistosoma mansoni	hypothetical protein	0.0165	0.4951	0.4951
Brugia malayi	Ets-domain containing protein	0.0074	0.1862	0.1862
Leishmania major	cathepsin L-like protease	0.0059	0.1367	0.3168
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0059	0.1367	0.3201
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.009	0.2405	0.2405
Entamoeba histolytica	cysteine protease, putative	0.0035	0.0554	0.4054
Onchocerca volvulus		0.0059	0.1367	1
Entamoeba histolytica	cysteine proteinase, putative	0.0035	0.0554	0.4054
Entamoeba histolytica	cysteine protease, putative	0.0035	0.0554	0.4054
Loa Loa (eye worm)	beta-lactamase	0.0035	0.0566	0.0566
Mycobacterium leprae	conserved hypothetical protein	0.0035	0.0566	0.5
Brugia malayi	beta-lactamase family protein	0.0035	0.0566	0.0566
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0566	0.0566
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0059	0.1367	0.3201
Schistosoma mansoni	hypothetical protein	0.0165	0.4951	0.4951
Trichomonas vaginalis	D-aminoacylase, putative	0.0035	0.0566	0.1831
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0035	0.0554	0.0554
Entamoeba histolytica	cysteine protease, putative	0.0035	0.0554	0.4054
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0059	0.1367	0.4419
Onchocerca volvulus		0.0035	0.0566	0.4142
Leishmania major	cathepsin L-like protease	0.0059	0.1367	0.3168
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.009	0.2405	0.2405
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0059	0.1367	0.4419
Entamoeba histolytica	cysteine proteinase, putative	0.0035	0.0554	0.4054
Leishmania major	cathepsin L-like protease	0.0059	0.1367	0.3168
Leishmania major	cathepsin L-like protease	0.0059	0.1367	0.3168
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.009	0.2405	0.2405
Echinococcus multilocularis	cysteine protease	0.0059	0.1367	0.1367
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0035	0.0554	0.0554
Trypanosoma cruzi	cysteine peptidase, putative	0.0035	0.0554	0.0554
Entamoeba histolytica	cysteine protease, putative	0.0035	0.0554	0.4054
Loa Loa (eye worm)	hypothetical protein	0.0315	1	1
Trypanosoma brucei	cysteine peptidase C (CPC)	0.011	0.3093	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.1367	0.4419
Entamoeba histolytica	cysteine protease, putative	0.0035	0.0554	0.4054
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0059	0.1367	0.3201
Trypanosoma cruzi	cysteine proteinase, putative	0.0035	0.0554	0.0554
Echinococcus multilocularis	cathepsin b	0.0315	1	1
Entamoeba histolytica	cysteine protease, putative	0.0035	0.0554	0.4054
Onchocerca volvulus		0.0059	0.1367	1
Brugia malayi	beta-lactamase family protein	0.0035	0.0566	0.0566
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.009	0.2405	0.2405
Echinococcus granulosus	cathepsin l1	0.0059	0.1367	0.1367
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0059	0.1367	0.4419
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0225	0.695	1
Brugia malayi	Papain family cysteine protease containing protein	0.0059	0.1367	0.1367
Entamoeba histolytica	cysteine proteinase 1, putative	0.0035	0.0554	0.4054
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0059	0.1367	0.3201
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.1367	0.4419
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0035	0.0566	0.0566
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.1367	0.4419
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0035	0.0554	0.0554
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0035	0.0566	0.0566
Leishmania major	cathepsin L-like protease	0.0059	0.1367	0.3168
Plasmodium vivax	vivapain-2	0.0059	0.1367	1
Entamoeba histolytica	cysteine proteinase, putative	0.0059	0.1367	1
Trypanosoma cruzi	cysteine proteinase, putative	0.0035	0.0554	0.0554
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0035	0.0566	0.5
Loa Loa (eye worm)	hypothetical protein	0.0059	0.1367	0.1367
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.009	0.2405	0.2405
Mycobacterium ulcerans	beta-lactamase	0.0035	0.0566	0.5
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0315	1	1
Trichomonas vaginalis	D-aminoacylase, putative	0.0035	0.0566	0.1831
Trichomonas vaginalis	esterase, putative	0.0035	0.0566	0.1831
Onchocerca volvulus		0.0059	0.1367	1
Leishmania major	cathepsin L-like protease	0.0059	0.1367	0.3168
Entamoeba histolytica	cysteine protease, putative	0.0035	0.0554	0.4054
Echinococcus multilocularis	cathepsin b	0.0315	1	1
Echinococcus multilocularis	geminin	0.0165	0.4951	0.4951
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0035	0.0554	0.1791
Echinococcus granulosus	geminin	0.0165	0.4951	0.4951
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.011	0.3093	1
Schistosoma mansoni	cathepsin F (C01 family)	0.0059	0.1367	0.1367
Loa Loa (eye worm)	fibroinase	0.0059	0.1367	0.1367
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0035	0.0566	0.0566
Echinococcus granulosus	cathepsin l1	0.0042	0.0813	0.0813
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0059	0.1367	0.4419
Brugia malayi	beta-lactamase	0.0035	0.0566	0.0566
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.011	0.3093	0.3093
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0059	0.1367	0.1367
Echinococcus granulosus	GA binding protein alpha chain	0.0074	0.1862	0.1862
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.011	0.3093	0.3093
Onchocerca volvulus		0.0035	0.0566	0.4142
Echinococcus multilocularis	GA binding protein alpha chain	0.0074	0.1862	0.1862
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0042	0.0813	0.2627
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0059	0.1367	0.1367
Plasmodium vivax	vivapain-1	0.0035	0.0554	0.4054
Brugia malayi	Ets-domain containing protein	0.0074	0.1862	0.1862
Loa Loa (eye worm)	hypothetical protein	0.0063	0.1502	0.1502
Leishmania major	cathepsin L-like protease	0.0059	0.1367	0.3168
Brugia malayi	cathepsin L-like precursor	0.0042	0.0813	0.0813
Trypanosoma cruzi	cruzipain precursor, putative	0.0059	0.1367	0.1367
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.0315	1	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 906760