Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0086 | 0.086 | 0.086 |
Echinococcus granulosus | cathepsin l1 | 0.0086 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0086 | 0.086 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0161 | 0.2688 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Onchocerca volvulus | Cathepsin F homolog | 0.0086 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine protease, putative | 0.0086 | 0.086 | 1 |
Schistosoma mansoni | P2X receptor subunit | 0.0199 | 0.3609 | 0.3609 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0199 | 0.3609 | 0.3609 |
Loa Loa (eye worm) | cathepsin B | 0.0161 | 0.2688 | 0.2482 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Loa Loa (eye worm) | fibroinase | 0.0086 | 0.086 | 0.0603 |
Onchocerca volvulus | 0.0086 | 0.086 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0161 | 0.2688 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0274 | 0.0274 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0199 | 0.3609 | 0.3609 |
Onchocerca volvulus | 0.0086 | 0.086 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Schistosoma mansoni | P2X receptor subunit | 0.0199 | 0.3609 | 0.3609 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0086 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0086 | 0.086 | 0.086 |
Echinococcus multilocularis | cathepsin b | 0.0462 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0462 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Echinococcus granulosus | cathepsin b | 0.0462 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.086 | 0.086 |
Schistosoma mansoni | P2X receptor subunit | 0.0199 | 0.3609 | 0.3609 |
Onchocerca volvulus | Cathepsin L homolog | 0.0086 | 0.086 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0062 | 0.0274 | 0.0274 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0462 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Brugia malayi | cathepsin L-like precursor | 0.0062 | 0.0274 | 0.0274 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0086 | 0.086 | 0.0603 |
Onchocerca volvulus | 0.0086 | 0.086 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.086 | 0.0603 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0274 | 0.0274 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0462 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0086 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.086 | 0.086 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0199 | 0.3609 | 0.3609 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0086 | 0.086 | 0.086 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0462 | 1 | 1 |
Toxoplasma gondii | cathepsin B | 0.0161 | 0.2688 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.086 | 0.086 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0086 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Echinococcus granulosus | cathepsin l1 | 0.0062 | 0.0274 | 0.0274 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Schistosoma mansoni | P2X receptor subunit | 0.0199 | 0.3609 | 0.3609 |
Loa Loa (eye worm) | ctsf protein | 0.0086 | 0.086 | 0.0603 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0086 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.086 | 0.086 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0086 | 0.086 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0086 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0086 | 0.086 | 0.086 |
Onchocerca volvulus | 0.0086 | 0.086 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0062 | 0.0274 | 0.3182 |
Loa Loa (eye worm) | cysteine protease | 0.0086 | 0.086 | 0.0603 |
Onchocerca volvulus | 0.0086 | 0.086 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0086 | 0.086 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0062 | 0.0274 | 0.0274 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0086 | 0.086 | 0.086 |
Echinococcus multilocularis | cathepsin b | 0.0462 | 1 | 1 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0161 | 0.2688 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0161 | 0.2688 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0086 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0462 | 1 | 1 |
Onchocerca volvulus | 0.0086 | 0.086 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0086 | 0.086 | 0.086 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0161 | 0.2688 | 0.2688 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0086 | 0.086 | 0.086 |
Onchocerca volvulus | 0.0086 | 0.086 | 1 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0086 | 0.086 | 0.086 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0462 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Echinococcus multilocularis | cysteine protease | 0.0086 | 0.086 | 0.086 |
Plasmodium vivax | vivapain-2 | 0.0086 | 0.086 | 1 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0199 | 0.3609 | 0.3609 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0199 | 0.3609 | 0.3609 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0161 | 0.2688 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0274 | 0.1018 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0086 | 0.086 | 0.086 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0062 | 0.0274 | 0.0274 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Giardia lamblia | Cathepsin B precursor | 0.0161 | 0.2688 | 0.5 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0199 | 0.3609 | 0.3609 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0086 | 0.086 | 0.0603 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Echinococcus multilocularis | cysteine protease | 0.0086 | 0.086 | 0.086 |
Plasmodium vivax | vivapain-2 | 0.0086 | 0.086 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0274 | 0.1018 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0161 | 0.2688 | 0.2688 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0086 | 0.086 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0086 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Echinococcus granulosus | cathepsin b | 0.0462 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.