Detailed information for compound 910088
Basic information
Technical information
- TDR Targets ID: 910088
- Name: 2-methoxy-N-(6-methyl-4,5,6,7-tetrahydro-1,3- benzothiazol-2-yl)benzamide
- MW: 302.391 | Formula: C16H18N2O2S
-
H donors: 1
H acceptors: 2
LogP: 3.61
Rotable bonds: 4
Rule of 5 violations (Lipinski): 1 - SMILES: COc1ccccc1C(=O)Nc1nc2c(s1)CC(CC2)C
- InChi: 1S/C16H18N2O2S/c1-10-7-8-12-14(9-10)21-16(17-12)18-15(19)11-5-3-4-6-13(11)20-2/h3-6,10H,7-9H2,1-2H3,(H,17,18,19)
- InChiKey: ZTRONNUTSZLVMA-UHFFFAOYSA-N
Network
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Synonyms
- IFLab1_000133
- Oprea1_581367
- IDI1_008352
Targets
Known targets for this compound
No curated genes were found associated with this compound
Predicted pathogen targets for this compound
By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model
Ranking Plot
Putative Targets List
| Species | Potential target | Raw | Global | Species |
|---|---|---|---|---|
| Mycobacterium ulcerans | ketoacyl reductase | 0.0056 | 1 | 1 |
| Onchocerca volvulus | 0.0056 | 1 | 0.5 | |
| Mycobacterium tuberculosis | Probable short-chain dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Echinococcus granulosus | retinol dehydrogenase 11 | 0.0056 | 1 | 0.5 |
| Leishmania major | oxidoreductase-like protein | 0.0056 | 1 | 1 |
| Leishmania major | hypothetical protein, conserved | 0.0056 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0056 | 1 | 1 |
| Onchocerca volvulus | 0.0056 | 1 | 0.5 | |
| Entamoeba histolytica | hypothetical protein | 0.0056 | 1 | 0.5 |
| Leishmania major | quinonoid dihydropteridine reductase | 0.0056 | 1 | 1 |
| Plasmodium vivax | hypothetical protein, conserved | 0.0056 | 1 | 0.5 |
| Leishmania major | dehydrogenase-like protein | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Onchocerca volvulus | 0.0056 | 1 | 0.5 | |
| Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Leishmania major | hypothetical protein, conserved | 0.0056 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | carbonyl reductase | 0.0056 | 1 | 0.5 |
| Giardia lamblia | Short-chain dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Probable oxidoreductase | 0.0056 | 1 | 0.5 |
| Loa Loa (eye worm) | oxidoreductase | 0.0056 | 1 | 1 |
| Leishmania major | short chain dehydrogenase/reductase, putative | 0.0056 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short-chain dehydrogenase | 0.0056 | 1 | 1 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Entamoeba histolytica | short chain dehydrogenase family protein | 0.0056 | 1 | 0.5 |
| Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Trypanosoma cruzi | short chain dehydrogenase/reductase, putative | 0.0056 | 1 | 1 |
| Trichomonas vaginalis | short-chain dehydrogenases/reductase, putative | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0056 | 1 | 0.5 |
| Mycobacterium tuberculosis | Probable shortchain dehydrogenase | 0.0056 | 1 | 0.5 |
| Entamoeba histolytica | oxidoreductase, short chain dehydrogenase/reductase family | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0056 | 1 | 0.5 |
| Mycobacterium tuberculosis | Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0056 | 1 | 0.5 |
| Trypanosoma cruzi | beta-ketoacyl-ACP reductase 2, putative | 0.0056 | 1 | 1 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0056 | 1 | 0.5 |
| Mycobacterium tuberculosis | Probable oxidoreductase | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Entamoeba histolytica | 3-ketodihydrosphingosine reductase protein, putative | 0.0056 | 1 | 0.5 |
| Loa Loa (eye worm) | hypothetical protein | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | ketoacyl reductase | 0.0056 | 1 | 1 |
| Trypanosoma cruzi | 3-ketoacyl-CoA reductase, putative | 0.0056 | 1 | 1 |
| Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0056 | 1 | 1 |
| Echinococcus granulosus | 3 ketodihydrosphingosine reductase | 0.0056 | 1 | 0.5 |
| Brugia malayi | dehydrogenases, short chain protein 2 | 0.0056 | 1 | 1 |
| Leishmania major | hypothetical protein, conserved | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 1 | 1 |
| Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0056 | 1 | 0.5 |
| Mycobacterium tuberculosis | Possible short-chain dehydrogenase EphD | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0056 | 1 | 1 |
| Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 0.5 |
| Giardia lamblia | Oxidoreductase, short chain dehydrogenase/reductase family | 0.0056 | 1 | 0.5 |
| Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Plasmodium vivax | steroid dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Loa Loa (eye worm) | oxidoreductase | 0.0056 | 1 | 1 |
| Leishmania major | short chain dehydrogenase, putative | 0.0056 | 1 | 1 |
| Loa Loa (eye worm) | oxidoreductase | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | oxidoreductase short chain dehydrogenase/reductase family | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Plasmodium falciparum | oxidoreductase, short-chain dehydrogenase family, putative | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short-chain dehydrogenase | 0.0056 | 1 | 1 |
| Echinococcus multilocularis | carbonyl reductase 1 | 0.0056 | 1 | 0.5 |
| Mycobacterium tuberculosis | Probable oxidoreductase | 0.0056 | 1 | 0.5 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Entamoeba histolytica | hypothetical protein, conserved | 0.0056 | 1 | 0.5 |
| Trypanosoma cruzi | hypothetical protein, conserved | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Echinococcus multilocularis | epidermal retinal dehydrogenase 2 | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 1 | 1 |
| Trypanosoma cruzi | hypothetical protein, conserved | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Loa Loa (eye worm) | oxidoreductase | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 1 | 1 |
| Echinococcus granulosus | carbonyl reductase 1 | 0.0056 | 1 | 0.5 |
| Loa Loa (eye worm) | oxidoreductase | 0.0056 | 1 | 1 |
| Leishmania major | quinonoid dihydropteridine reductase | 0.0056 | 1 | 1 |
| Brugia malayi | Cytochrome P450 family protein | 0.0032 | 0.3185 | 0.3185 |
| Leishmania major | short chain dehydrogenase/reductase, putative | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Probable oxidoreductase | 0.0056 | 1 | 0.5 |
| Echinococcus granulosus | hypothetical protein | 0.0056 | 1 | 0.5 |
| Echinococcus multilocularis | steroid dehydrogenase | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short-chain membrane-associated dehydrogenase | 0.0056 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 1 | 1 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Echinococcus multilocularis | carbonyl reductase 1 | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | oxidoreductase | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Probable short chain alcohol dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Echinococcus granulosus | carbonyl reductase 1 | 0.0056 | 1 | 0.5 |
| Leishmania major | pteridine reductase 1 | 0.0056 | 1 | 1 |
| Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0056 | 1 | 0.5 |
| Loa Loa (eye worm) | hypothetical protein | 0.0056 | 1 | 1 |
| Echinococcus granulosus | hypothetical protein | 0.0056 | 1 | 0.5 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Trypanosoma cruzi | short chain dehydrogenase/reductase, putative | 0.0056 | 1 | 1 |
| Toxoplasma gondii | carbonyl reductase 1, putative | 0.0056 | 1 | 0.5 |
| Entamoeba histolytica | short chain dehydrogenase family protein | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | oxidoreductase | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Leishmania major | hypothetical protein, conserved | 0.0056 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0056 | 1 | 0.5 |
| Mycobacterium leprae | Probable oxidoreductase | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | ketoacyl reductase | 0.0056 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short-chain dehydrogenase | 0.0056 | 1 | 1 |
| Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 0.5 |
| Onchocerca volvulus | 0.0056 | 1 | 0.5 | |
| Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Trypanosoma cruzi | quinonoid dihydropteridine reductase, putative | 0.0056 | 1 | 1 |
| Echinococcus granulosus | Dehydrogenase:reductase SDR family | 0.0056 | 1 | 0.5 |
| Trypanosoma brucei | 3-keto-dihydrosphingosine reductase | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | carbonyl reductase | 0.0056 | 1 | 0.5 |
| Loa Loa (eye worm) | oxidoreductase | 0.0056 | 1 | 1 |
| Trypanosoma cruzi | NAD(P)-dependent oxidoreductase, putative | 0.0056 | 1 | 1 |
| Echinococcus granulosus | WW domain containing oxidoreductase | 0.0056 | 1 | 0.5 |
| Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Toxoplasma gondii | sterol carrier protein-2 HAD-2SCP-2 | 0.0056 | 1 | 0.5 |
| Onchocerca volvulus | Sepiapterin reductase homolog | 0.0056 | 1 | 0.5 |
| Trypanosoma brucei | beta-ketoacyl-ACP reductase 3, putative | 0.0056 | 1 | 1 |
| Echinococcus granulosus | retinol dehydrogenase 11 | 0.0056 | 1 | 0.5 |
| Onchocerca volvulus | 0.0056 | 1 | 0.5 | |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short-chain dehydrogenase | 0.0056 | 1 | 1 |
| Echinococcus granulosus | carbonyl reductase 1 | 0.0056 | 1 | 0.5 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Possible fatty acyl-CoA reductase | 0.0056 | 1 | 0.5 |
| Trypanosoma cruzi | beta-ketoacyl-ACP reductase 2, putative | 0.0056 | 1 | 1 |
| Brugia malayi | dehydrogenases, short chain protein 9 | 0.0056 | 1 | 1 |
| Trypanosoma cruzi | hypothetical protein, conserved | 0.0056 | 1 | 1 |
| Echinococcus multilocularis | conserved hypothetical protein | 0.0056 | 1 | 0.5 |
| Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Trypanosoma cruzi | 3-keto-dihydrosphingosine reductase | 0.0056 | 1 | 1 |
| Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 0.5 |
| Toxoplasma gondii | 3-ketoacyl-CoA reductase, putative | 0.0056 | 1 | 0.5 |
| Loa Loa (eye worm) | dehydrogenase | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Loa Loa (eye worm) | short chain dehydrogenase/reductase family oxidoreductase | 0.0056 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Leishmania major | quinonoid dihydropteridine reductase | 0.0056 | 1 | 1 |
| Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0056 | 1 | 1 |
| Trypanosoma cruzi | hypothetical protein, conserved | 0.0056 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Brugia malayi | hypothetical protein | 0.0056 | 1 | 1 |
| Leishmania major | 3-keto-dihydrosphingosine reductase | 0.0056 | 1 | 1 |
| Trichomonas vaginalis | estradiol 17 beta-dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Schistosoma mansoni | carbonyl reductase | 0.0056 | 1 | 0.5 |
| Toxoplasma gondii | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short-chain type oxidoreductase | 0.0056 | 1 | 1 |
| Onchocerca volvulus | 0.0056 | 1 | 0.5 | |
| Echinococcus multilocularis | carbonyl reductase 1 | 0.0056 | 1 | 0.5 |
| Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0056 | 1 | 1 |
| Leishmania major | short chain dehydrogenase-like protein | 0.0056 | 1 | 1 |
| Trypanosoma brucei | beta-ketoacyl-ACP reductase 2 | 0.0056 | 1 | 1 |
| Toxoplasma gondii | oxidoreductase, putative | 0.0056 | 1 | 0.5 |
| Brugia malayi | oxidoreductase | 0.0056 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Mycobacterium leprae | Probable short-chain type dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Leishmania major | short chain dehydrogenase, putative | 0.0056 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0056 | 1 | 1 |
| Echinococcus multilocularis | carbonyl reductase 1 | 0.0056 | 1 | 0.5 |
| Brugia malayi | D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor | 0.0056 | 1 | 1 |
| Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0056 | 1 | 1 |
| Giardia lamblia | Hypothetical protein | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0056 | 1 | 1 |
| Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0056 | 1 | 1 |
| Echinococcus multilocularis | steroid dehydrogenase | 0.0056 | 1 | 0.5 |
| Brugia malayi | hypothetical protein | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Probable oxidoreductase | 0.0056 | 1 | 0.5 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Echinococcus granulosus | carbonyl reductase 1 | 0.0056 | 1 | 0.5 |
| Trypanosoma cruzi | short-chain dehydrogenase, putative | 0.0056 | 1 | 1 |
| Mycobacterium leprae | PROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE | 0.0056 | 1 | 0.5 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Echinococcus granulosus | epidermal retinal dehydrogenase 2 | 0.0056 | 1 | 0.5 |
| Onchocerca volvulus | 0.0056 | 1 | 0.5 | |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 1 | 1 |
| Echinococcus multilocularis | estradiol 17 beta dehydrogenase 12 | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0056 | 1 | 0.5 |
| Loa Loa (eye worm) | hypothetical protein | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Possible oxidoreductase | 0.0056 | 1 | 0.5 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Loa Loa (eye worm) | dehydrogenase | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Trypanosoma cruzi | hypothetical protein, conserved | 0.0056 | 1 | 1 |
| Brugia malayi | Dehydrogenases, short chain protein 2 | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Mycobacterium tuberculosis | Possible iron-regulated short-chain dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Trypanosoma brucei | short-chain dehydrogenase, putative | 0.0056 | 1 | 1 |
| Echinococcus multilocularis | 3 ketodihydrosphingosine reductase | 0.0056 | 1 | 0.5 |
| Loa Loa (eye worm) | hypothetical protein | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | dehydrogenase | 0.0056 | 1 | 1 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0056 | 1 | 0.5 |
| Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 1 | 0.5 |
| Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0056 | 1 | 1 |
| Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.0056 | 1 | 0.5 |
| Mycobacterium tuberculosis | Probable oxidoreductase | 0.0056 | 1 | 0.5 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Trypanosoma cruzi | 3-keto-dihydrosphingosine reductase | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Possible ketoacyl reductase | 0.0056 | 1 | 0.5 |
| Trypanosoma cruzi | NAD(P)-dependent oxidoreductase, putative | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Schistosoma mansoni | 3-keto-dihydrosphingosine reductase | 0.0056 | 1 | 0.5 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Probable short-chain type oxidoreductase | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | steroid dehydrogenase | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Trichomonas vaginalis | hydroxyacyl dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Echinococcus multilocularis | retinol dehydrogenase 13 | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | dehydrogenase/reductase | 0.0056 | 1 | 1 |
| Trypanosoma cruzi | short chain dehydrogenase, putative | 0.0056 | 1 | 1 |
| Onchocerca volvulus | 0.0056 | 1 | 0.5 | |
| Leishmania major | quinonoid dihydropteridine reductase | 0.0056 | 1 | 1 |
| Trypanosoma cruzi | hypothetical protein, conserved | 0.0056 | 1 | 1 |
| Toxoplasma gondii | oxidoreductase, putative | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Leishmania major | quinonoid dihydropteridine reductase | 0.0056 | 1 | 1 |
| Schistosoma mansoni | short-chain dehydrogenase/reductase | 0.0056 | 1 | 0.5 |
| Loa Loa (eye worm) | oxidoreductase | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Probable dehydrogenase | 0.0056 | 1 | 0.5 |
| Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0056 | 1 | 0.5 |
| Onchocerca volvulus | 0.0056 | 1 | 0.5 | |
| Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0056 | 1 | 1 |
| Echinococcus multilocularis | transient receptor potential cation channel | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Trypanosoma brucei | oxidoreductase-like protein | 0.0056 | 1 | 1 |
| Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 13 homolog | 0.0056 | 1 | 0.5 |
| Trypanosoma brucei | 3-ketoacyl-CoA reductase, putative | 0.0056 | 1 | 1 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Plasmodium falciparum | steroid dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 1 | 1 |
| Brugia malayi | Hypothetical oxidoreductase F56D1.5 | 0.0056 | 1 | 1 |
| Trypanosoma brucei | beta-D-hydroxybutyrate dehydrogenase | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Decaprenylphosphoryl-D-2-keto erythro pentose reductase | 0.0056 | 1 | 0.5 |
| Brugia malayi | Dehydrogenases, short chain protein 30 | 0.0056 | 1 | 1 |
| Mycobacterium leprae | ROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | 0.0056 | 1 | 0.5 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Echinococcus multilocularis | oxidoreductase | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Loa Loa (eye worm) | oxidoreductase | 0.0056 | 1 | 1 |
| Mycobacterium tuberculosis | Possible oxidoreductase | 0.0056 | 1 | 0.5 |
| Entamoeba histolytica | hypothetical protein, conserved | 0.0056 | 1 | 0.5 |
| Trypanosoma cruzi | short-chain dehydrogenase, putative | 0.0056 | 1 | 1 |
| Echinococcus granulosus | oxidoreductase | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | dehydrogenase/decarboxylase protein | 0.0056 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Onchocerca volvulus | 0.0056 | 1 | 0.5 | |
| Trichomonas vaginalis | short-chain dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Onchocerca volvulus | 0.0056 | 1 | 0.5 | |
| Loa Loa (eye worm) | hypothetical protein | 0.0056 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0056 | 1 | 1 |
| Echinococcus multilocularis | Dehydrogenase:reductase SDR family | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | carveol-like dehydrogenase | 0.0056 | 1 | 1 |
| Trichomonas vaginalis | steroid dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0056 | 1 | 0.5 |
| Leishmania major | quinonoid dihydropteridine reductase | 0.0056 | 1 | 1 |
| Onchocerca volvulus | Dehydrogenase\/reductase SDR family member 1 homolog | 0.0056 | 1 | 0.5 |
| Giardia lamblia | Reductase, putative | 0.0056 | 1 | 0.5 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 1 | 1 |
| Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0056 | 1 | 1 |
| Mycobacterium leprae | Possible short-chain dehydrogenase EphD | 0.0056 | 1 | 0.5 |
| Leishmania major | quinonoid dihydropteridine reductase | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Schistosoma mansoni | short chain dehydrogenase | 0.0056 | 1 | 0.5 |
| Echinococcus granulosus | steroid dehydrogenase | 0.0056 | 1 | 0.5 |
| Brugia malayi | Retinol dehydrogenase 12 | 0.0056 | 1 | 1 |
| Trypanosoma cruzi | 3-ketoacyl-CoA reductase, putative | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short chain dehydrogenase | 0.0056 | 1 | 1 |
| Loa Loa (eye worm) | cytochrome P450 family protein | 0.0032 | 0.3185 | 0.3185 |
| Loa Loa (eye worm) | oxidoreductase | 0.0056 | 1 | 1 |
| Entamoeba histolytica | estradiol 17-beta-dehydrogenase, putative | 0.0056 | 1 | 0.5 |
| Echinococcus multilocularis | retinol dehydrogenase 11 | 0.0056 | 1 | 0.5 |
| Onchocerca volvulus | 0.0056 | 1 | 0.5 | |
| Leishmania major | hypothetical protein, conserved | 0.0056 | 1 | 1 |
| Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 1 | 1 |
| Onchocerca volvulus | 0.0056 | 1 | 0.5 | |
| Schistosoma mansoni | retinal dehydrogenase | 0.0056 | 1 | 0.5 |
Activities
No activities found for this compound.
Phenotypes
Whole-cell/tissue/organism interactions
We have no records of whole-cell/tissue assays done with this compound
What does this mean?
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
Annotated phenotypes:
We have no manually annotated phenotypes for this drug.
What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by
drugs, or by genetic manipulation of cells (e.g. gene knockouts or
knockdowns) is manually curated from the literature. These
descriptions help to describe the potential of the target for drug
development. If no information is available for this gene or if the
information is incomplete, this may mean that i) the papers
containing this information either appeared after the curation
effort for this organism was carried out or they were inadvertently
missed by curators; or that ii) the curation effort for this
organism has not yet started.
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.
External resources for this compound
- Search by Saint Jude
Bibliographic References
No literature references available for this target.
If you have references for this compound, please enter them in a user comment (below) or Contact us.