Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | long chain fatty acid elongation enzyme, putative | 0.0401 | 0 | 0.5 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.0442 | 1 | 0.5 |
Leishmania major | fatty acid elongase, putative | 0.0401 | 0 | 0.5 |
Leishmania major | fatty acid elongase, putative | 0.0401 | 0 | 0.5 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.0442 | 1 | 0.5 |
Trypanosoma brucei | Fatty acid elongase | 0.0401 | 0 | 0.5 |
Plasmodium vivax | GNS1/SUR4 domain containing protein | 0.0401 | 0 | 0.5 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0401 | 0 | 0.5 |
Toxoplasma gondii | GNS1/SUR4 family protein | 0.0401 | 0 | 0.5 |
Brugia malayi | Fatty acid elongation protein 3 | 0.0401 | 0 | 0.5 |
Plasmodium falciparum | fatty acid elongation protein, GNS1/SUR4 family, putative | 0.0401 | 0 | 0.5 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0401 | 0 | 0.5 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.0442 | 1 | 0.5 |
Brugia malayi | GNS1/SUR4 family protein | 0.0401 | 0 | 0.5 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0401 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0442 | 1 | 1 |
Leishmania major | fatty acid elongase, putative | 0.0401 | 0 | 0.5 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0401 | 0 | 0.5 |
Toxoplasma gondii | integral membrane protein, GNS1/SUR4 family protein, putative | 0.0401 | 0 | 0.5 |
Echinococcus multilocularis | hormone sensitive lipase | 0.0442 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.