Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | elongation of very long chain fatty acids | 0.0061 | 0.1029 | 0.1355 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0275 | 0.0351 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0012 | 0.0112 | 0.0133 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0012 | 0.0112 | 0.0133 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0012 | 0.0112 | 0.0133 |
Schistosoma mansoni | elongation of fatty acids protein 1 | 0.0061 | 0.1029 | 0.1019 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0112 | 0.01 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0462 | 0.0422 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0012 | 0.0112 | 0.01 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.1411 | 0.1375 |
Schistosoma mansoni | biogenic amine receptor | 0.0012 | 0.0112 | 0.01 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0112 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0539 | 0.0496 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0417 | 0.0375 |
Schistosoma mansoni | amine GPCR | 0.0012 | 0.0112 | 0.01 |
Brugia malayi | Melatonin receptor type 1A | 0.0012 | 0.0112 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Schistosoma mansoni | opsin-like receptor | 0.0012 | 0.0112 | 0.01 |
Schistosoma mansoni | hypothetical protein | 0.0304 | 0.5632 | 0.5627 |
Echinococcus multilocularis | allatostatin A receptor | 0.0012 | 0.0112 | 0.0133 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0462 | 0.0451 |
Loa Loa (eye worm) | ELO-9 protein | 0.0061 | 0.1029 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0012 | 0.0112 | 0.007 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0012 | 0.0112 | 0.007 |
Loa Loa (eye worm) | GNS1/SUR4 family protein | 0.0301 | 0.5578 | 0.5558 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Schistosoma mansoni | neuropeptide receptor | 0.0012 | 0.0112 | 0.01 |
Toxoplasma gondii | fatty acid elongase | 0.0061 | 0.1029 | 0.1423 |
Echinococcus multilocularis | g protein coupled receptor | 0.0012 | 0.0112 | 0.0133 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | Serotonin receptor | 0.0012 | 0.0112 | 0.007 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0539 | 0.0497 |
Schistosoma mansoni | neuropeptide receptor | 0.0012 | 0.0112 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0539 | 0.0496 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Onchocerca volvulus | 0.0035 | 0.0539 | 0.4649 | |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0275 | 0.0351 |
Schistosoma mansoni | ran | 0.0021 | 0.0275 | 0.0264 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0462 | 0.06 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0034 | 0.052 | 0.0461 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0012 | 0.0112 | 0.0133 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0012 | 0.0112 | 0.01 |
Schistosoma mansoni | amine GPCR | 0.0012 | 0.0112 | 0.01 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0044 | 0.0044 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.0895 | 0.117 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0539 | 0.0496 |
Echinococcus multilocularis | serotonin receptor | 0.0012 | 0.0112 | 0.0133 |
Echinococcus granulosus | sex peptide receptor | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | G-protein coupled receptor | 0.0012 | 0.0112 | 0.007 |
Echinococcus multilocularis | fmrfamide receptor | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0462 | 0.042 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0417 | 0.054 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0539 | 0.0496 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0112 | 0.01 |
Leishmania major | long chain polyunsaturated fatty acid elongation enzyme-like protein | 0.0061 | 0.1029 | 0.1423 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0417 | 0.0268 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | GnHR receptor homolog | 0.0012 | 0.0112 | 0.007 |
Leishmania major | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0034 | 0.052 | 0.0477 |
Brugia malayi | Serotonin receptor | 0.0012 | 0.0112 | 0.007 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0097 | 0.1724 | 0.1687 |
Brugia malayi | fatty acid elongation protein 3 | 0.0061 | 0.1029 | 0.0991 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0417 | 0.0268 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0112 | 0.007 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Echinococcus granulosus | snurportin 1 | 0.0304 | 0.5632 | 0.7482 |
Brugia malayi | fatty acid elongation protein 3 | 0.0061 | 0.1029 | 0.0991 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0539 | 0.0496 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0539 | 0.0497 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0012 | 0.0112 | 0.0133 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Loa Loa (eye worm) | glutaminase | 0.0535 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0404 | 0.7524 | 0.7521 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0462 | 0.0451 |
Leishmania major | fatty acid elongase, putative | 0.0301 | 0.5578 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0539 | 0.0539 |
Leishmania major | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0012 | 0.0112 | 0.0133 |
Trypanosoma brucei | Fatty acid elongase | 0.0061 | 0.1029 | 0.1423 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0462 | 0.06 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0462 | 0.0451 |
Brugia malayi | neuropeptide F receptor | 0.0012 | 0.0112 | 0.007 |
Brugia malayi | fatty acid elongation protein 3 | 0.0061 | 0.1029 | 0.0991 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0539 | 0.0539 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0301 | 0.5578 | 1 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0417 | 0.0406 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0462 | 0.0451 |
Schistosoma mansoni | myosin xvIII | 0.0012 | 0.0112 | 0.01 |
Brugia malayi | larval opioid receptor | 0.0012 | 0.0112 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0539 | 0.0496 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0539 | 0.0701 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0097 | 0.1724 | 0.1689 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0012 | 0.0112 | 0.0133 |
Echinococcus multilocularis | neuropeptide receptor | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0012 | 0.0112 | 0.0068 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0112 | 0.01 |
Echinococcus multilocularis | snurportin 1 | 0.0304 | 0.5632 | 0.7482 |
Leishmania major | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0012 | 0.0112 | 0.007 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.114 | 0.1102 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0012 | 0.0112 | 0.01 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0112 | 0.007 |
Loa Loa (eye worm) | fatty acid elongation protein 3 | 0.0061 | 0.1029 | 0.0989 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Echinococcus granulosus | somatostatin receptor | 0.0012 | 0.0112 | 0.0133 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0417 | 0.0268 |
Plasmodium vivax | long chain polyunsaturated fatty acid elongation enzyme, putative | 0.0061 | 0.1029 | 0.1423 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0012 | 0.0112 | 0.0133 |
Echinococcus multilocularis | serotonin receptor | 0.0012 | 0.0112 | 0.0133 |
Echinococcus multilocularis | g protein coupled receptor | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0304 | 0.5632 | 0.5613 |
Echinococcus granulosus | allatostatin A receptor | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | sulfakinin receptor protein | 0.0012 | 0.0112 | 0.007 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0012 | 0.0112 | 0.0133 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0223 | 0.4096 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0112 | 0.01 |
Schistosoma mansoni | opsin-like receptor | 0.0012 | 0.0112 | 0.01 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0404 | 0.7524 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0012 | 0.0112 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0462 | 0.06 |
Brugia malayi | follicle stimulating hormone receptor | 0.0012 | 0.0112 | 0.007 |
Toxoplasma gondii | GNS1/SUR4 family protein | 0.0301 | 0.5578 | 1 |
Leishmania major | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Brugia malayi | Dopamine receptor protein 1 | 0.0012 | 0.0112 | 0.007 |
Echinococcus granulosus | fmrfamide receptor | 0.0012 | 0.0112 | 0.0133 |
Plasmodium falciparum | fatty acid elongation protein, GNS1/SUR4 family, putative | 0.0301 | 0.5578 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0012 | 0.0112 | 0.0133 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0012 | 0.0112 | 0.01 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.114 | 0.113 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0012 | 0.0112 | 0.0133 |
Echinococcus multilocularis | sex peptide receptor | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0539 | 0.0496 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0112 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Leishmania major | fatty acid elongase, putative | 0.0301 | 0.5578 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0012 | 0.0112 | 0.0133 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0539 | 0.0497 |
Echinococcus granulosus | dnaJ subfamily B | 0.0404 | 0.7524 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0539 | 0.0527 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0012 | 0.0112 | 0.0133 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0112 | 0.01 |
Schistosoma mansoni | elongation of fatty acids protein 1 | 0.0061 | 0.1029 | 0.1019 |
Onchocerca volvulus | Elongation of very long chain fatty acids protein homolog | 0.0061 | 0.1029 | 1 |
Trypanosoma brucei | Fatty acid elongase | 0.0061 | 0.1029 | 0.1423 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0012 | 0.0112 | 0.0133 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0012 | 0.0112 | 0.01 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0012 | 0.0112 | 0.0068 |
Plasmodium vivax | GNS1/SUR4 domain containing protein | 0.0301 | 0.5578 | 1 |
Echinococcus multilocularis | somatostatin receptor | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0462 | 0.042 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0462 | 0.06 |
Echinococcus granulosus | orexin receptor type 2 | 0.0012 | 0.0112 | 0.0133 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.0275 | 0.0275 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0539 | 0.0498 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0012 | 0.0112 | 0.01 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0012 | 0.0112 | 0.0068 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0112 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.1724 | 0.1687 |
Echinococcus granulosus | serotonin receptor | 0.0012 | 0.0112 | 0.0133 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0112 | 0.007 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0012 | 0.0112 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0034 | 0.052 | 0.0461 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0112 | 0.01 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0012 | 0.0112 | 0.0068 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0315 | 1 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0275 | 0.0232 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | putative neuropeptide receptor | 0.0012 | 0.0112 | 0.007 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0539 | 0.0497 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Trichomonas vaginalis | glutaminase, putative | 0.0535 | 1 | 1 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0315 | 0.0315 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0012 | 0.0112 | 0.007 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0012 | 0.0112 | 0.0133 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0112 | 0.01 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0112 | 0.01 |
Schistosoma mansoni | neuropeptide receptor | 0.0012 | 0.0112 | 0.01 |
Echinococcus granulosus | neuropeptide s receptor | 0.0012 | 0.0112 | 0.0133 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0315 | 0.0315 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0539 | 0.0497 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0012 | 0.0112 | 0.0133 |
Echinococcus multilocularis | elongation of very long chain fatty acids | 0.0061 | 0.1029 | 0.1355 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0462 | 0.06 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0539 | 0.0498 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0012 | 0.0112 | 0.01 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0539 | 0.0527 |
Plasmodium falciparum | long chain polyunsaturated fatty acid elongation enzyme, putative | 0.0061 | 0.1029 | 0.1423 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0539 | 0.5 |
Schistosoma mansoni | elongation of fatty acids protein 1 | 0.0061 | 0.1029 | 0.1019 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0539 | 0.0539 |
Brugia malayi | GNS1/SUR4 family protein | 0.0301 | 0.5578 | 0.5559 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0446 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0417 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Onchocerca volvulus | 0.0035 | 0.0539 | 0.4649 | |
Brugia malayi | hypothetical protein | 0.0012 | 0.0112 | 0.007 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0112 | 0.01 |
Leishmania major | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0539 | 0.0498 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0012 | 0.0112 | 0.007 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0539 | 0.0498 |
Loa Loa (eye worm) | GNS1/SUR4 family protein | 0.0061 | 0.1029 | 0.0989 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.1017 | 0.1006 |
Echinococcus multilocularis | fmrfamide receptor | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | Fatty acid elongation protein 3 | 0.0301 | 0.5578 | 0.5559 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0417 | 0.0268 |
Onchocerca volvulus | 0.0035 | 0.0539 | 0.4649 | |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0012 | 0.0112 | 0.007 |
Schistosoma mansoni | elongation of fatty acids protein 1 | 0.0061 | 0.1029 | 0.1019 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0012 | 0.0112 | 0.0068 |
Schistosoma mansoni | amine GPCR | 0.0012 | 0.0112 | 0.01 |
Brugia malayi | Augmenter of liver regeneration | 0.0034 | 0.052 | 0.0479 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0417 | 0.0268 |
Brugia malayi | Dopamine receptor | 0.0012 | 0.0112 | 0.007 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0012 | 0.0112 | 0.0133 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0034 | 0.052 | 0.0461 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0012 | 0.0112 | 0.0133 |
Trypanosoma brucei | Long chain fatty acyl elongase | 0.0061 | 0.1029 | 0.1423 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0539 | 0.0497 |
Echinococcus granulosus | neuropeptide receptor | 0.0012 | 0.0112 | 0.0133 |
Toxoplasma gondii | integral membrane protein, GNS1/SUR4 family protein, putative | 0.0301 | 0.5578 | 1 |
Schistosoma mansoni | ran | 0.0021 | 0.0275 | 0.0264 |
Schistosoma mansoni | biogenic amine receptor | 0.0012 | 0.0112 | 0.01 |
Loa Loa (eye worm) | fatty acid elongation protein 3 | 0.0301 | 0.5578 | 0.5558 |
Echinococcus multilocularis | elongation of very long chain fatty acids | 0.0061 | 0.1029 | 0.1355 |
Brugia malayi | Dopamine receptor protein 2 | 0.0012 | 0.0112 | 0.007 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0415 | 0.0404 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.1029 | 0.0989 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Echinococcus granulosus | g protein coupled receptor | 0.0012 | 0.0112 | 0.0133 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0275 | 0.0234 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0012 | 0.0112 | 0.01 |
Leishmania major | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | G-protein coupled receptor | 0.0012 | 0.0112 | 0.007 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | glutaminase 2 | 0.0535 | 1 | 1 |
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0034 | 0.052 | 0.0676 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0112 | 0.007 |
Echinococcus granulosus | g protein coupled receptor | 0.0012 | 0.0112 | 0.0133 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0012 | 0.0112 | 0.01 |
Echinococcus granulosus | neuropeptide receptor | 0.0012 | 0.0112 | 0.0133 |
Onchocerca volvulus | 0.0061 | 0.1029 | 1 | |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0012 | 0.0112 | 0.01 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0012 | 0.0112 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0539 | 0.0496 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0012 | 0.0112 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0012 | 0.0112 | 0.0133 |
Mycobacterium ulcerans | glutaminase | 0.0535 | 1 | 1 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0012 | 0.0112 | 0.0068 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0315 | 0.0076 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0012 | 0.0112 | 0.0133 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0012 | 0.0112 | 0.0133 |
Echinococcus multilocularis | g protein coupled receptor | 0.0012 | 0.0112 | 0.0133 |
Onchocerca volvulus | Elongation of very long chain fatty acids protein homolog | 0.0061 | 0.1029 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0446 | 0.0435 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0112 | 0.01 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0012 | 0.0112 | 0.01 |
Brugia malayi | neuropeptide F receptor | 0.0012 | 0.0112 | 0.007 |
Trypanosoma brucei | elongation of very long chain fatty acids protein, putative | 0.0061 | 0.1029 | 0.1423 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0012 | 0.0112 | 0.007 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0539 | 0.0539 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0112 | 0.007 |
Schistosoma mansoni | biogenic amine receptor | 0.0012 | 0.0112 | 0.01 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0012 | 0.0112 | 0.0133 |
Onchocerca volvulus | Elongation of very long chain fatty acids protein 5 homolog | 0.0061 | 0.1029 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0012 | 0.0112 | 0.0068 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0034 | 0.052 | 0.0676 |
Brugia malayi | fatty acid elongation protein 3 | 0.0061 | 0.1029 | 0.0991 |
Echinococcus granulosus | hypothetical protein | 0.0012 | 0.0112 | 0.0133 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0034 | 0.052 | 0.0461 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.052 | 0.0461 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0415 | 0.0372 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Leishmania major | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Schistosoma mansoni | neuropeptide receptor | 0.0012 | 0.0112 | 0.01 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0446 | 0.0578 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0112 | 0.007 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | ORL1-like opioid receptor | 0.0012 | 0.0112 | 0.007 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0012 | 0.0112 | 0.0133 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | GNS1/SUR4 family protein | 0.0061 | 0.1029 | 0.0991 |
Onchocerca volvulus | 0.0028 | 0.0415 | 0.3305 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Brugia malayi | RE15519p | 0.0012 | 0.0112 | 0.007 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0012 | 0.0112 | 0.01 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0012 | 0.0112 | 0.0133 |
Onchocerca volvulus | 0.0061 | 0.1029 | 1 | |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0539 | 0.0539 |
Echinococcus granulosus | g-protein coupled receptor | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0012 | 0.0112 | 0.0068 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0539 | 0.5 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0012 | 0.0112 | 0.0133 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0034 | 0.052 | 0.0461 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0301 | 0.5578 | 1 |
Leishmania major | fatty acid elongase, putative | 0.0301 | 0.5578 | 1 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0112 | 0.007 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0275 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Schistosoma mansoni | amine GPCR | 0.0012 | 0.0112 | 0.01 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0012 | 0.0112 | 0.01 |
Echinococcus granulosus | g protein coupled receptor | 0.0012 | 0.0112 | 0.0133 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | fatty acid elongation protein 3 | 0.0061 | 0.1029 | 0.0989 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0462 | 0.0422 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0315 | 0.0315 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Leishmania major | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0012 | 0.0112 | 0.01 |
Schistosoma mansoni | adenoreceptor | 0.0012 | 0.0112 | 0.01 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0462 | 0.06 |
Plasmodium vivax | elongation of very long chain fatty acids protein 3, putative | 0.0061 | 0.1029 | 0.1423 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0012 | 0.0112 | 0.0068 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0012 | 0.0112 | 0.01 |
Leishmania major | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0415 | 0.0374 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0034 | 0.052 | 0.0461 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0012 | 0.0112 | 0.01 |
Loa Loa (eye worm) | fatty acid elongation protein 3 | 0.0061 | 0.1029 | 0.0989 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0539 | 0.0539 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0301 | 0.5578 | 1 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0012 | 0.0112 | 0.0133 |
Plasmodium falciparum | long chain fatty acid elongation enzyme, putative | 0.0301 | 0.5578 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Brugia malayi | hypothetical protein | 0.0012 | 0.0112 | 0.007 |
Trypanosoma cruzi | fatty acid elongase, putative | 0.0301 | 0.5578 | 1 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0034 | 0.052 | 0.0461 |
Brugia malayi | AKH receptor | 0.0012 | 0.0112 | 0.007 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0012 | 0.0112 | 0.0068 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0012 | 0.0112 | 0.0068 |
Schistosoma mansoni | fatty acid acyl transferase-related | 0.0061 | 0.1029 | 0.1019 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0315 | 0.0076 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0012 | 0.0112 | 0.01 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0012 | 0.0112 | 0.0133 |
Echinococcus granulosus | elongation of very long chain fatty acids | 0.0061 | 0.1029 | 0.1355 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0097 | 0.1724 | 0.1689 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Schistosoma mansoni | opsin-like receptor | 0.0012 | 0.0112 | 0.01 |
Brugia malayi | Hypothetical 34.1 kDa protein C40H1.4 in chromosome III | 0.0061 | 0.1029 | 0.0991 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0034 | 0.052 | 0.0461 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0012 | 0.0112 | 0.0133 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0446 | 0.0435 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0012 | 0.0112 | 0.0133 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0012 | 0.0112 | 0.0133 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0539 | 0.0701 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0012 | 0.0112 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0012 | 0.0112 | 0.01 |
Leishmania major | fatty acid elongase, putative | 0.0061 | 0.1029 | 0.1423 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.114 | 0.1101 |
Schistosoma mansoni | amine GPCR | 0.0012 | 0.0112 | 0.01 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0417 | 0.0377 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0012 | 0.0112 | 0.007 |
Trypanosoma brucei | Fatty acid elongase | 0.0301 | 0.5578 | 1 |
Schistosoma mansoni | glutaminase | 0.0535 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0112 | 0.0068 |
Brugia malayi | G protein-coupled receptor | 0.0012 | 0.0112 | 0.007 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Competitive binding affinity to human full length recombinant GST-tagged eIF4E expressed in Escherichia coli BL21(DE3) assessed as inhibition of eIF4E/eIF4G interaction by fluorescence polarization assay relative to parent compound | ChEMBL. | 24675136 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.