Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0021 | 0.0274 | 0.0274 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0149 | 0.1732 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0029 | 0.086 | 1 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0149 | 0.0149 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0149 | 0.0149 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Brugia malayi | Melatonin receptor type 1A | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0149 | 0.0149 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0149 | 0.1732 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | Dopamine receptor protein 1 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0153 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0021 | 0.0274 | 0.0274 |
Brugia malayi | Cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | cysteine protease | 0.0029 | 0.086 | 0.0722 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Brugia malayi | ORL1-like opioid receptor | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0053 | 0.2688 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | G protein-coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Toxoplasma gondii | cathepsin B | 0.0053 | 0.2688 | 1 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0051 | 0.2513 | 1 |
Brugia malayi | sulfakinin receptor protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0029 | 0.086 | 0.0722 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cysteine protease | 0.0029 | 0.086 | 0.086 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0149 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | Dopamine receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | RNA helicase, putative | 0.0138 | 0.8886 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | sex peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Brugia malayi | Dopamine receptor protein 2 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | cathepsin b | 0.0153 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | orexin receptor type 2 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0053 | 0.2688 | 0.2688 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0053 | 0.2688 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0021 | 0.0274 | 0.3182 |
Brugia malayi | RE15519p | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 1 | 1 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0051 | 0.2513 | 0.24 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Brugia malayi | Serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | hypothetical protein | 0.0138 | 0.8886 | 0.8886 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus granulosus | allatostatin A receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0149 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0029 | 0.086 | 0.2619 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0029 | 0.086 | 1 |
Echinococcus granulosus | somatostatin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0153 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | fibroinase | 0.0029 | 0.086 | 0.0722 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Echinococcus granulosus | neuropeptide s receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin b | 0.0153 | 1 | 1 |
Brugia malayi | GnHR receptor homolog | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | neuropeptide F receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0029 | 0.086 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | myosin xvIII | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | g-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | TYRA-2 protein | 0.0051 | 0.2513 | 0.24 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Brugia malayi | G-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.086 | 0.0722 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0029 | 0.086 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | follicle stimulating hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0021 | 0.0274 | 0.1018 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | allatostatin A receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | cathepsin l1 | 0.0029 | 0.086 | 0.086 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | sex peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cysteine protease | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0149 | 0.1732 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | Cathepsin F homolog | 0.0029 | 0.086 | 0.2619 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Plasmodium vivax | vivapain-2 | 0.0029 | 0.086 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | putative neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | larval opioid receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Toxoplasma gondii | cathepsin CPL | 0.0029 | 0.086 | 0.2802 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0021 | 0.0274 | 0.1018 |
Brugia malayi | Serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | cathepsin b | 0.0153 | 1 | 1 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0149 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine protease, putative | 0.0029 | 0.086 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0029 | 0.086 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0029 | 0.086 | 0.2802 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | histamine h1 receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0149 | 0.0554 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | AKH receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | Cathepsin L homolog | 0.0029 | 0.086 | 0.2619 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0051 | 0.2513 | 1 |
Brugia malayi | neuropeptide F receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin b | 0.0153 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | cathepsin B | 0.0053 | 0.2688 | 0.2577 |
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0029 | 0.086 | 0.0722 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | cathepsin l1 | 0.0021 | 0.0274 | 0.0274 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0149 | 0.0149 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0149 | 0.5 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Plasmodium vivax | vivapain-2 | 0.0029 | 0.086 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | adenoreceptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0149 | 0.0149 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0149 | 0.0168 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | ctsf protein | 0.0029 | 0.086 | 0.0722 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0149 | 0.0149 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | somatostatin receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0053 | 0.2688 | 0.2688 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0149 | 0.0554 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0021 | 0.0274 | 0.0274 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0053 | 0.2688 | 0.3024 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0149 | 0.0149 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 12 % | The concentration to inhibit cell proliferation of PC3 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 14 % | The concentration to inhibit cell proliferation of PC3 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 18 % | The concentration to inhibit colony formation of Ishikawa human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 18 % | The concentration to inhibit colony formation of MCF-7 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 18 % | The concentration to inhibit cell proliferation of MCF-7 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 18 % | The concentration to inhibit cell proliferation of MDA-MB-231 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 19 % | The concentration to inhibit cell proliferation of MDA-MB-231 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 20 % | The concentration to inhibit cell proliferation of MCF-7 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 21 % | The concentration to inhibit colony formation of PC3 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 32 % | The concentration to inhibit cell proliferation of LNCaP human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 40 % | The concentration to inhibit cell proliferation of LNCaP human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 44 % | The concentration to inhibit colony formation of MDA-MB-231 humantumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 45 % | The concentration to inhibit colony formation of MCF-7 human tumour cell lines | ChEMBL. | 9341910 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.