Detailed information for compound 934437

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 163.259 | Formula: C11H17N
  • H donors: 1 H acceptors: 0 LogP: 2.56 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC[C@@H](Cc1ccccc1)N
  • InChi: 1S/C11H17N/c1-2-6-11(12)9-10-7-4-3-5-8-10/h3-5,7-8,11H,2,6,9,12H2,1H3/t11-/m0/s1
  • InChiKey: VXGQDFOHLMAZIV-NSHDSACASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0271 0.1672 1
Echinococcus multilocularis lamin 0.0028 0.0085 0.0085
Mycobacterium leprae PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE 0.0759 0.4858 1
Mycobacterium tuberculosis Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insen 0.0464 0.2932 0.3704
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0046 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0153 0.0222
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0221 0.022
Echinococcus multilocularis mitogen activated protein kinase 11 0.1388 0.8959 0.8959
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0138 0.0802 0.1305
Schistosoma mansoni serine/threonine protein kinase 0.0413 0.2599 0.2599
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0221 0.022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0221 0.022
Schistosoma mansoni inositol monophosphatase 0.0038 0.0152 0.0152
Trichomonas vaginalis penicillin-binding protein, putative 0.0187 0.1123 0.2237
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0046 0.0046
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0271 0.1672 0.1824
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0343 0.0343
Mycobacterium tuberculosis Probable hydrolase 0.0187 0.1123 0.1316
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0085 0.0085
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0066 0.0334 0.0274
Brugia malayi intermediate filament protein 0.0028 0.0085 0.0095
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0343 0.0343
Mycobacterium ulcerans lipoprotein LpqF 0.0066 0.0334 0.0365
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0153 0.0152
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.1173 0.7558 0.7558
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0085 0.0085
Mycobacterium tuberculosis Conserved protein 0.0187 0.1123 0.1316
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0046 0.0046
Schistosoma mansoni hypothetical protein 0.0386 0.2418 0.2418
Brugia malayi RNA, U transporter 1 0.0085 0.0458 0.0511
Schistosoma mansoni importin beta-1 0.003 0.0098 0.0097
Trichomonas vaginalis D-aminoacylase, putative 0.0187 0.1123 0.2237
Loa Loa (eye worm) hypothetical protein 0.0187 0.1123 0.1123
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0187 0.1123 0.1253
Brugia malayi beta-lactamase family protein 0.0187 0.1123 0.1253
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0343 0.0343
Treponema pallidum penicillin-binding protein (pbp-2) 0.0759 0.4858 1
Echinococcus multilocularis cyclin dependent kinase 1 0.0271 0.1672 0.1672
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0401 0.0401
Trypanosoma cruzi hypothetical protein, conserved 0.0187 0.1123 0.1208
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.1547 1 1
Echinococcus granulosus geminin 0.0386 0.2418 0.2418
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0153 0.012
Echinococcus multilocularis mitogen activated protein kinase 11 0.1388 0.8959 0.8959
Trypanosoma cruzi cdc2-related kinase 1 0.0271 0.1672 0.1824
Echinococcus granulosus dual specificity 0.0413 0.2599 0.2599
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0413 0.2599 0.2881
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0153 0.0222
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0153 0.0152
Loa Loa (eye worm) hypothetical protein 0.04 0.2513 0.2513
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0153 0.0419
Plasmodium vivax importin-beta 2, putative 0.003 0.0098 0.0317
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0152 0.0221
Mycobacterium ulcerans penicillin-binding protein PbpA 0.0424 0.2672 0.5061
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0221 0.022
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0098 0.0082
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0046 0.0046
Giardia lamblia Kinase, CMGC CDK 0.0271 0.1672 1
Loa Loa (eye worm) hypothetical protein 0.0187 0.1123 0.1123
Brugia malayi Protein kinase domain containing protein 0.0413 0.2599 0.2901
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0046 0.0051
Loa Loa (eye worm) hypothetical protein 0.04 0.2513 0.2513
Onchocerca volvulus 0.0187 0.1123 1
Brugia malayi beta-lactamase family protein 0.0187 0.1123 0.1253
Trichomonas vaginalis penicillin-binding protein, putative 0.0187 0.1123 0.2237
Schistosoma mansoni hypothetical protein 0.0386 0.2418 0.2418
Loa Loa (eye worm) hypothetical protein 0.003 0.0098 0.0098
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0152 0.0152
Loa Loa (eye worm) inositol-1 0.0038 0.0152 0.0152
Mycobacterium tuberculosis Probable penicillin-binding protein PbpA 0.0424 0.2672 0.3361
Mycobacterium tuberculosis Possible penicillin-binding lipoprotein 0.0185 0.1112 0.1302
Echinococcus granulosus hypothetical protein 0.0451 0.2846 0.2846
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0221 0.0246
Loa Loa (eye worm) hypothetical protein 0.1547 1 1
Mycobacterium tuberculosis Probable lipase LipE 0.0187 0.1123 0.1316
Brugia malayi Importin beta-1 subunit 0.003 0.0098 0.0109
Toxoplasma gondii ABC1 family protein 0.0187 0.1123 0.6622
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1388 0.8959 1
Brugia malayi TAR-binding protein 0.0068 0.0343 0.0383
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.1547 1 1
Mycobacterium leprae conserved hypothetical protein 0.0187 0.1123 0.2106
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0413 0.2599 0.2864
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0271 0.1672 0.1672
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0343 0.0343
Entamoeba histolytica protein kinase domain containing protein 0.0413 0.2599 1
Echinococcus granulosus intermediate filament protein 0.0028 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.032 0.1989 0.1989
Brugia malayi Inositol-1 0.0038 0.0152 0.017
Schistosoma mansoni serine/threonine protein kinase 0.1173 0.7558 0.7558
Loa Loa (eye worm) hypothetical protein 0.0741 0.4736 0.4736
Brugia malayi cell division control protein 2 homolog 0.0271 0.1672 0.1866
Trypanosoma brucei cdc2-related kinase 1 0.0271 0.1672 0.1844
Mycobacterium tuberculosis Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) (PBP1): penicillin-insensitive transglycosylase 0.0295 0.1829 0.2248
Mycobacterium ulcerans penicillin-binding lipoprotein 0.0185 0.1112 0.1928
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0271 0.1672 0.1824
Mycobacterium ulcerans lipase LipD 0.0187 0.1123 0.1949
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0153 0.0152
Chlamydia trachomatis transglycolase/transpeptidase 0.0711 0.4543 1
Echinococcus granulosus lamin dm0 0.0028 0.0085 0.0085
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0152 0.012
Mycobacterium leprae POSSIBLE PENICILLIN-BINDING LIPOPROTEIN 0.0185 0.1112 0.2083
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0061 0.003
Echinococcus multilocularis lamin dm0 0.0028 0.0085 0.0085
Entamoeba histolytica cell division protein kinase 2, putative 0.0271 0.1672 0.6369
Echinococcus granulosus importin subunit beta 1 0.003 0.0098 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0153 0.0222
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1388 0.8959 1
Echinococcus multilocularis dual specificity 0.0413 0.2599 0.2599
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0187 0.1123 0.1122
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0153 0.0152
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0098 0.0317
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0413 0.2599 0.2864
Mycobacterium leprae PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSEN 0.0464 0.2932 0.5929
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0066 0.0334 0.0439
Brugia malayi RNA binding protein 0.0068 0.0343 0.0383
Echinococcus granulosus beta LACTamase domain containing family member 0.0187 0.1123 0.1122
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0187 0.1123 0.1123
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0343 0.0343
Mycobacterium tuberculosis Probable lipase LipD 0.0187 0.1123 0.1316
Schistosoma mansoni serine/threonine protein kinase 0.0271 0.1672 0.1672
Echinococcus granulosus tar DNA binding protein 0.0068 0.0343 0.0343
Mycobacterium leprae Probable penicillin-binding membrane protein PbpB 0.0237 0.1446 0.2789
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0187 0.1123 0.1316
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0061 0.003
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0343 0.0343
Entamoeba histolytica cell division protein kinase 2, putative 0.0271 0.1672 0.6369
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0153 0.0152
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0152 0.0143
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0413 0.2599 0.2599
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0138 0.0802 0.0892
Loa Loa (eye worm) RNA binding protein 0.0068 0.0343 0.0343
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0187 0.1123 0.1316
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0187 0.1123 0.1316
Trichomonas vaginalis CMGC family protein kinase 0.0271 0.1672 0.3379
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.1388 0.8959 0.8959
Loa Loa (eye worm) hypothetical protein 0.0038 0.0153 0.0153
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0061 0.003
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0271 0.1672 0.1672
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0152 0.0152
Giardia lamblia Kinase, CMGC CDK 0.0271 0.1672 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0221 0.022
Echinococcus multilocularis snurportin 1 0.032 0.1989 0.1989
Entamoeba histolytica hypothetical protein 0.0024 0.0061 0.0057
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0153 0.0152
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.1388 0.8959 1
Schistosoma mansoni intermediate filament proteins 0.0028 0.0085 0.0085
Echinococcus granulosus cyclin dependent kinase 1 0.0271 0.1672 0.1672
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0271 0.1672 0.1672
Schistosoma mansoni peptidase 0.0016 0.0008 0.0008
Echinococcus granulosus cyclin dependent kinase 0.0271 0.1672 0.1672
Wolbachia endosymbiont of Brugia malayi cell division protein FtsI 0.0711 0.4543 1
Mycobacterium tuberculosis Probable penicillin-binding membrane protein PbpB 0.0237 0.1446 0.1743
Mycobacterium ulcerans bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 0.0464 0.2932 0.5583
Loa Loa (eye worm) hypothetical protein 0.0187 0.1123 0.1123
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0401 0.0401
Brugia malayi P38 map kinase family protein 2 0.1388 0.8959 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.032 0.1989 0.1989
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0221 0.022
Schistosoma mansoni lamin 0.0028 0.0085 0.0085
Onchocerca volvulus 0.0187 0.1123 1
Plasmodium vivax protein kinase Crk2 0.0271 0.1672 1
Echinococcus multilocularis geminin 0.0386 0.2418 0.2418
Loa Loa (eye worm) beta-lactamase 0.0187 0.1123 0.1123
Echinococcus multilocularis mitogen activated protein kinase 14 0.1388 0.8959 0.8959
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0187 0.1123 0.1949
Echinococcus granulosus mitogen activated protein kinase 14 0.1388 0.8959 0.8959
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0221 0.022
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0343 0.0343
Trichomonas vaginalis CMGC family protein kinase 0.0271 0.1672 0.3379
Loa Loa (eye worm) hypothetical protein 0.0187 0.1123 0.1123
Echinococcus multilocularis cyclin dependent kinase 0.0271 0.1672 0.1672
Mycobacterium tuberculosis Conserved protein 0.0187 0.1123 0.1316
Plasmodium vivax hypothetical protein, conserved 0.0187 0.1123 0.6622
Schistosoma mansoni lamin 0.0028 0.0085 0.0085
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0271 0.1672 0.1672
Trichomonas vaginalis D-aminoacylase, putative 0.0187 0.1123 0.2237
Mycobacterium ulcerans bifunctional penicillin-binding protein 1A/1B PonA1 0.0759 0.4858 0.9454
Echinococcus multilocularis importin subunit beta 1 0.003 0.0098 0.0097
Entamoeba histolytica protein kinase, putative 0.0413 0.2599 1
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0098 0.0082
Mycobacterium ulcerans esterase/lipase LipP 0.0187 0.1123 0.1949
Mycobacterium leprae Probable lipase LipE 0.0187 0.1123 0.2106
Echinococcus multilocularis musashi 0.0028 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0187 0.1123 0.1123
Echinococcus granulosus snurportin 1 0.032 0.1989 0.1989
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0153 0.012
Leishmania major importin beta-1 subunit, putative 0.0024 0.0061 0.0016
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0343 0.0383
Schistosoma mansoni ran 0.0022 0.0046 0.0046
Schistosoma mansoni ran 0.0022 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0187 0.1123 0.1123
Echinococcus multilocularis mitogen activated protein kinase 14 0.1388 0.8959 0.8959
Mycobacterium ulcerans multidrug-transport integral membrane protein Mmr 0.0202 0.1219 0.2142
Echinococcus multilocularis cyclin dependent kinase 1 0.0271 0.1672 0.1672
Trypanosoma brucei cdc2-related kinase 3 0.0271 0.1672 0.1844
Mycobacterium ulcerans multidrugs-transport integral membrane protein Mmr-like 0.0801 0.513 1
Brugia malayi Protein kinase domain containing protein 0.0271 0.1672 0.1866
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0061 0.0016
Trypanosoma brucei hypothetical protein, conserved 0.0187 0.1123 0.1229
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1195 0.7701 1
Echinococcus granulosus cyclin dependent kinase 5 0.0271 0.1672 0.1672
Entamoeba histolytica protein kinase, putative 0.0413 0.2599 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0153 0.0171
Echinococcus multilocularis beta LACTamase domain containing family member 0.0187 0.1123 0.1122
Brugia malayi hypothetical protein 0.0741 0.4736 0.5286
Trichomonas vaginalis conserved hypothetical protein 0.0759 0.4858 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0187 0.1123 0.1122
Mycobacterium ulcerans hypothetical protein 0.0187 0.1123 0.1949
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0152 0.0655
Brugia malayi Protein kinase domain containing protein 0.0028 0.0085 0.0095
Echinococcus granulosus lamin 0.0028 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0028 0.0082 0.0082
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0152 0.0221
Trypanosoma cruzi hypothetical protein, conserved 0.0187 0.1123 0.1208
Loa Loa (eye worm) hypothetical protein 0.0258 0.1586 0.1586
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0153 0.0657
Loa Loa (eye worm) hypothetical protein 0.0028 0.0085 0.0085
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0085 0.0095
Loa Loa (eye worm) hypothetical protein 0.0741 0.4736 0.4736
Trypanosoma cruzi cdc2-related kinase 3 0.0271 0.1672 0.1824
Mycobacterium ulcerans penicillin-binding membrane protein PbpB 0.0709 0.4528 0.879
Plasmodium falciparum protein kinase 5 0.0271 0.1672 1
Brugia malayi Protein kinase domain containing protein 0.1173 0.7558 0.8436
Brugia malayi beta-lactamase 0.0187 0.1123 0.1253
Trichomonas vaginalis esterase, putative 0.0187 0.1123 0.2237
Mycobacterium leprae Probable penicillin-binding protein PbpA 0.0424 0.2672 0.5379
Trypanosoma brucei beta lactamase 0.0066 0.0334 0.0346
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0153 0.012
Mycobacterium tuberculosis Probable esterase LipL 0.0187 0.1123 0.1316
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0152 0.0221
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0152 0.012
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0221 0.0221
Leishmania major hypothetical protein, conserved 0.0187 0.1123 0.1208
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0152 0.0417
Mycobacterium tuberculosis Conserved protein 0.0187 0.1123 0.1316
Trypanosoma cruzi cdc2-related kinase 3 0.0271 0.1672 0.1824
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0153 0.0143
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0153 0.0152
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0413 0.2599 0.2864
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0153 0.0152
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.1388 0.8959 1
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0343 0.0343
Echinococcus multilocularis cyclin dependent kinase 5 0.0271 0.1672 0.1672
Plasmodium falciparum importin beta, putative 0.003 0.0098 0.0317
Schistosoma mansoni serine/threonine protein kinase 0.0271 0.1672 0.1672
Treponema pallidum penicillin-binding protein (pbp-1) 0.0711 0.4543 0.0472
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0923 0.5923 0.5923
Echinococcus granulosus mitogen activated protein kinase 11 0.1388 0.8959 0.8959
Trichomonas vaginalis D-aminoacylase, putative 0.0187 0.1123 0.2237
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0152 0.012
Brugia malayi Serotonin receptor 0.0303 0.1883 0.2101
Mycobacterium ulcerans beta-lactamase 0.0187 0.1123 0.1949
Trypanosoma cruzi cdc2-related kinase 1 0.0271 0.1672 0.1824
Entamoeba histolytica hypothetical protein 0.0413 0.2599 1
Onchocerca volvulus 0.0187 0.1123 1
Trichomonas vaginalis CMGC family protein kinase 0.0271 0.1672 0.3379
Echinococcus multilocularis conserved hypothetical protein 0.0443 0.2793 0.2793
Schistosoma mansoni inositol monophosphatase 0.0038 0.0152 0.0152

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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