Detailed information for compound 940530

Basic information

Technical information
  • TDR Targets ID: 940530
  • Name: (2S)-5,7-dimethoxy-2-phenylchroman-4-one
  • MW: 284.307 | Formula: C17H16O4
  • H donors: 0 H acceptors: 1 LogP: 2.85 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc2O[C@@H](CC(=O)c2c(c1)OC)c1ccccc1
  • InChi: 1S/C17H16O4/c1-19-12-8-15(20-2)17-13(18)10-14(21-16(17)9-12)11-6-4-3-5-7-11/h3-9,14H,10H2,1-2H3/t14-/m0/s1
  • InChiKey: IAFBOKYTDSDNHV-AWEZNQCLSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-5,7-dimethoxy-2-phenyl-chroman-4-one
  • (2S)-5,7-dimethoxy-2-phenyl-4-chromanone
  • ZINC00058119

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0137 0.0123
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Giardia lamblia Kinase 0.0017 0.0068 1
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0137 0.0123
Brugia malayi hypothetical protein 0.0017 0.0068 0.0022
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0931 1 1
Echinococcus multilocularis zinc finger protein Ran binding 0.0331 0.3483 0.3474
Schistosoma mansoni z-protein (S1r protein) 0.0023 0.0137 0.0123
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0137 0.0123
Giardia lamblia Ser/Thr protein kinase 0.0017 0.0068 1
Trypanosoma brucei predicted zinc finger protein 0.0017 0.0068 0.0155
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0331 0.3483 0.3474
Schistosoma mansoni hypothetical protein 0.0017 0.0068 0.0054
Leishmania major hypothetical protein, conserved 0.0331 0.3483 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0137 0.0123
Echinococcus granulosus E3 ubiquitin protein ligase MYLIP 0.0017 0.0068 0.0054
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0017 0.0068 0.0155
Echinococcus granulosus E3 ubiquitin protein ligase RNF146 0.0017 0.0068 0.0054
Chlamydia trachomatis SWIB complex protein 0.0931 1 0.5
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0137 0.0123
Chlamydia trachomatis DNA topoisomerase I 0.0931 1 0.5
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0137
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0046 0.0046
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0331 0.3483 0.3474
Giardia lamblia Hypothetical protein 0.0017 0.0068 1
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.0155
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0137
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0931 1 1
Echinococcus multilocularis ring and YY1 binding protein 0.0331 0.3483 0.3474
Echinococcus granulosus ring and YY1 binding protein 0.0331 0.3483 0.3474
Echinococcus multilocularis tumor protein p63 0.0328 0.3446 0.3437
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0331 0.3483 0.3483
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0069
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0931 1 1
Echinococcus granulosus expressed protein 0.0451 0.4783 0.4775
Plasmodium vivax DNA repair protein RAD5, putative 0.0017 0.0068 0.0054
Echinococcus multilocularis expressed protein 0.0451 0.4783 0.4775
Entamoeba histolytica hypothetical protein 0.0023 0.0137 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0068 0.0054
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.0137 0.0123
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0137 0.0123
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0931 1 1
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0017 0.0068 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.0155
Echinococcus granulosus E3 ubiquitin protein ligase Bre1 0.0017 0.0068 0.0054
Echinococcus granulosus cell growth regulator with ring finger domain 0.0017 0.0068 0.0054
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0137 0.0137
Trypanosoma cruzi hypothetical protein 0.0017 0.0068 0.0155
Brugia malayi Zinc finger, C2H2 type family protein 0.0017 0.0068 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0069
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Leishmania major hypothetical protein, conserved 0.0331 0.3483 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0069
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0137 0.0123
Trypanosoma cruzi hypothetical protein 0.0017 0.0068 0.0155
Schistosoma mansoni hypothetical protein 0.0931 1 1
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.0137 0.0123
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0137 0.0123
Entamoeba histolytica hypothetical protein 0.0023 0.0137 1
Plasmodium vivax E3 ubiquitin-protein ligase RNF5, putative 0.0017 0.0068 0.0054
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Echinococcus multilocularis ring finger protein 170 0.0017 0.0068 0.0054
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Schistosoma mansoni RNA binding protein 0.0331 0.3483 0.3474
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0137 0.0123
Giardia lamblia Hypothetical protein 0.0017 0.0068 1
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0137 0.0123
Echinococcus multilocularis RING finger and transmembrane domain containing protein 0.0017 0.0068 0.0054
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0931 1 1
Toxoplasma gondii hypothetical protein 0.0017 0.0068 0.0054
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Plasmodium falciparum RING zinc finger protein, putative 0.0017 0.0068 0.0054
Giardia lamblia Ribonuclease 0.0017 0.0068 1
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Giardia lamblia Zinc finger domain 0.0017 0.0068 1
Schistosoma mansoni rnf5 0.0017 0.0068 0.0054
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Giardia lamblia Hypothetical protein 0.0017 0.0068 1
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.0137 0.0091
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.0137 0.0123
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0137 0.0123
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0137 0.0123
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0331 0.3483 1
Brugia malayi hypothetical protein 0.0017 0.0068 0.0022
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0331 0.3483 0.3453
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Brugia malayi hypothetical protein 0.0023 0.0137 0.0091
Loa Loa (eye worm) RiNg Finger protein family member 0.0017 0.0068 0.0068
Brugia malayi hypothetical protein 0.0017 0.0068 0.0022
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.0155
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0015 0.0046 1
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0023 0.0137 0.0137
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Toxoplasma gondii RING zinc finger protein 0.0017 0.0068 0.0054
Toxoplasma gondii hypothetical protein 0.0017 0.0068 0.0054
Echinococcus granulosus ring finger protein 170 0.0017 0.0068 0.0054
Schistosoma mansoni ring finger protein 151 0.0017 0.0068 0.0054
Brugia malayi brahma associated protein 60 kDa 0.0931 1 1
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0331 0.3483 1
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0137 0.0123
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0137 0.0137
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.0137 0.0091
Onchocerca volvulus 0.0048 0.0406 0.034
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0331 0.3483 0.3453
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Echinococcus granulosus ring finger protein 113a 0.0017 0.0068 0.0054
Echinococcus granulosus Zinc finger RanBP2 type 0.0331 0.3483 0.3474
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Plasmodium falciparum E3 ubiquitin-protein ligase, putative 0.0017 0.0068 0.0054
Loa Loa (eye worm) hypothetical protein 0.0331 0.3483 0.3483
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Brugia malayi hypothetical protein 0.0017 0.0068 0.0022
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0137 0.0091
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0046 0.0093
Schistosoma mansoni peter pan-related 0.0017 0.0068 0.0054
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0331 0.3483 1
Onchocerca volvulus 0.0331 0.3483 0.3438
Plasmodium vivax RING zinc finger protein, putative 0.0017 0.0068 0.0054
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0931 1 1
Echinococcus granulosus RING finger and transmembrane domain containing protein 0.0017 0.0068 0.0054
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Plasmodium vivax hypothetical protein, conserved 0.0931 1 1
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0137 0.0123
Schistosoma mansoni peter pan-related 0.0017 0.0068 0.0054
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Plasmodium falciparum E3 ubiquitin-protein ligase RNF5, putative 0.0017 0.0068 0.0054
Plasmodium vivax E3 ubiquitin-protein ligase, putative 0.0017 0.0068 0.0054
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Entamoeba histolytica hypothetical protein 0.0023 0.0137 1
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0137 0.0123
Brugia malayi hypothetical protein 0.0017 0.0068 0.0022
Echinococcus multilocularis E3 ubiquitin protein ligase LRSAM1 0.0017 0.0068 0.0054
Brugia malayi regulator of G-protein signaling egl-10 0.0023 0.0137 0.0091
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0137
Plasmodium vivax trophozoite exported protein 1, putative 0.0017 0.0068 0.0054
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Entamoeba histolytica hypothetical protein 0.0017 0.0068 0.4407
Echinococcus multilocularis E3 ubiquitin protein ligase Bre1 0.0017 0.0068 0.0054
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0046 0.0046
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.0155
Leishmania major cytochrome p450-like protein 0.0015 0.0046 0.0093
Giardia lamblia Kinase, NEK 0.0017 0.0068 1
Echinococcus granulosus SWI:SNF matrix associated 0.0931 1 1
Schistosoma mansoni inhibitor of apoptosis 1 diap1 0.0017 0.0068 0.0054
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Trypanosoma brucei DNA repair protein, putative 0.0017 0.0068 0.0155
Schistosoma mansoni TRABID protein (C64 family) 0.0331 0.3483 0.3474
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Schistosoma mansoni brg-1 associated factor 0.0931 1 1
Brugia malayi Zinc finger protein 183 homolog 0.0017 0.0068 0.0022
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0017 0.0068 0.0054
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0137 0.0123
Onchocerca volvulus 0.0931 1 1
Trypanosoma brucei SNF2 family N-terminal domain/Ring finger domain containing protein, putative 0.0017 0.0068 0.0155
Giardia lamblia Hypothetical protein 0.0017 0.0068 1
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger) containing protein, putative 0.0017 0.0068 0.0155
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Brugia malayi Neuralized family protein 0.0017 0.0068 0.0022
Toxoplasma gondii helicase, putative 0.0017 0.0068 0.0054
Trypanosoma cruzi WLM domain containing protein, putative 0.0331 0.3483 1
Entamoeba histolytica SPRY domain protein 0.0017 0.0068 0.4407
Loa Loa (eye worm) hypothetical protein 0.0048 0.0406 0.0406
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0331 0.3483 1
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0137
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Giardia lamblia Hypothetical protein 0.0017 0.0068 1
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Toxoplasma gondii hypothetical protein 0.0017 0.0068 0.0054
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0331 0.3483 0.3453
Onchocerca volvulus 0.0331 0.3483 0.3438
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0137 0.0123
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Leishmania major hypothetical protein, conserved 0.0331 0.3483 1
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.0137 0.0123
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0137 0.0123
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Giardia lamblia Hypothetical protein 0.0017 0.0068 1
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0331 0.3483 0.3474
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Loa Loa (eye worm) hypothetical protein 0.0023 0.0137 0.0137
Echinococcus granulosus RING finger protein 185 0.0017 0.0068 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0069
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Brugia malayi PXA domain containing protein 0.0023 0.0137 0.0091
Trypanosoma brucei ring finger containing protein 0.0017 0.0068 0.0155
Echinococcus granulosus zinc finger protein Ran binding 0.0331 0.3483 0.3474
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Toxoplasma gondii SWI2/SNF2-containing protein RAD5 0.0017 0.0068 0.0054
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0023 0.0137 0.0069
Schistosoma mansoni hypothetical protein 0.0017 0.0068 0.0054
Loa Loa (eye worm) hypothetical protein 0.0331 0.3483 0.3483
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0137 0.0123
Loa Loa (eye worm) brahma associated protein 0.0931 1 1
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0331 0.3483 1
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Echinococcus granulosus E3 ubiquitin protein ligase LRSAM1 0.0017 0.0068 0.0054
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0137 0.0091
Schistosoma mansoni zinc finger protein 0.0017 0.0068 0.0054
Echinococcus multilocularis SWI:SNF matrix associated 0.0931 1 1
Trypanosoma brucei hypothetical protein, conserved 0.0331 0.3483 1
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0931 1 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0137 0.0091
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Brugia malayi RING zinc finger protein 0.0017 0.0068 0.0022
Giardia lamblia Zinc finger domain 0.0017 0.0068 1
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.0155
Schistosoma mansoni fusion 0.0331 0.3483 0.3474
Brugia malayi RING finger protein 20 0.0017 0.0068 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0137 0.0123
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0931 1 1
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Loa Loa (eye worm) hypothetical protein 0.0331 0.3483 0.3483
Echinococcus multilocularis 0.0017 0.0068 0.0054
Schistosoma mansoni hypothetical protein 0.0931 1 1
Toxoplasma gondii Bardet-Biedl syndrome 5, putative 0.0017 0.0068 0.0054
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Loa Loa (eye worm) hypothetical protein 0.0331 0.3483 0.3483
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0046 0.0046
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Brugia malayi PXA domain containing protein 0.0023 0.0137 0.0091
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0331 0.3483 1
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0406 0.0393
Leishmania major hypothetical protein, conserved 0.0331 0.3483 1
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Toxoplasma gondii ran binding protein 0.0331 0.3483 0.3474
Echinococcus multilocularis SWI:SNF matrix associated 0.0931 1 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Loa Loa (eye worm) RGS-3 protein 0.0023 0.0137 0.0137
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0137 0.0123
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0331 0.3483 0.3453
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Trypanosoma brucei cytochrome P450, putative 0.0015 0.0046 0.0093
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.0155
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0017 0.0068 0.0054
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Leishmania major DNA repair protein-like protein 0.0017 0.0068 0.0155
Brugia malayi hypothetical protein 0.0023 0.0137 0.0091
Schistosoma mansoni hypothetical protein 0.0331 0.3483 0.3474
Trichomonas vaginalis conserved hypothetical protein 0.0931 1 1
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0017 0.0068 0.0054
Leishmania major hypothetical protein 0.0017 0.0068 0.0155
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Schistosoma mansoni hypothetical protein 0.0017 0.0068 0.0054
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.0137 0.0123
Brugia malayi B-box zinc finger family protein 0.0017 0.0068 0.0022
Brugia malayi SWIB/MDM2 domain containing protein 0.0931 1 1
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0331 0.3483 0.3438
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0331 0.3483 1
Giardia lamblia Hypothetical protein 0.0017 0.0068 1
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Loa Loa (eye worm) RING finger protein 20 0.0017 0.0068 0.0068
Giardia lamblia E3 ubiquitin ligase for Rad6p required for the ubiquitination of histone H2B 0.0017 0.0068 1
Trypanosoma cruzi hypothetical protein, conserved 0.0331 0.3483 1
Schistosoma mansoni mind bomb 0.0017 0.0068 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0137 0.0069
Echinococcus multilocularis RING finger protein 185 0.0017 0.0068 0.0054
Brugia malayi hypothetical protein 0.0017 0.0068 0.0022
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0046 0.0093
Plasmodium falciparum trophozoite exported protein 1 0.0017 0.0068 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0137 0.0123
Plasmodium falciparum zinc finger protein, putative 0.0017 0.0068 0.0054
Onchocerca volvulus 0.0331 0.3483 0.3438
Trypanosoma cruzi WLM domain containing protein, putative 0.0331 0.3483 1
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0331 0.3483 1
Trypanosoma brucei hypothetical protein, conserved 0.0331 0.3483 1
Giardia lamblia Kinase, NEK 0.0017 0.0068 1
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0331 0.3483 0.3474
Echinococcus multilocularis SWI:SNF matrix associated 0.0931 1 1
Trypanosoma brucei Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Schistosoma mansoni zinc finger protein 0.0331 0.3483 0.3474
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0137 0.0123
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Leishmania major hypothetical protein, unknown function 0.0017 0.0068 0.0155
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0017 0.0068 0.0068
Schistosoma mansoni hypothetical protein 0.0931 1 1
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0137 0.0137
Plasmodium vivax zinc finger protein, putative 0.0017 0.0068 0.0054
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0331 0.3483 1
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Onchocerca volvulus 0.0331 0.3483 0.3438
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0068 0.0155
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Entamoeba histolytica zinc finger domain containing protein 0.0017 0.0068 0.4407
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0137 0.0123
Leishmania major hypothetical protein, conserved 0.0017 0.0068 0.0155
Echinococcus multilocularis ring finger protein 113a 0.0017 0.0068 0.0054
Echinococcus granulosus tumor protein p63 0.0328 0.3446 0.3437
Echinococcus multilocularis E3 ubiquitin protein ligase MYLIP 0.0017 0.0068 0.0054
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0137 0.0123
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0137 0.0123
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0017 0.0068 0.0155
Giardia lamblia Protein 21.1 0.0017 0.0068 1
Entamoeba histolytica hypothetical protein 0.0017 0.0068 0.4407
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0331 0.3483 0.3474
Brugia malayi YY1-associated factor 2 0.0331 0.3483 0.3453
Toxoplasma gondii hypothetical protein 0.0017 0.0068 0.0054
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.0137 0.0123
Leishmania major hypothetical protein, conserved 0.0331 0.3483 1
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0017 0.0068 0.0054
Brugia malayi Hypothetical RING finger protein C16C10.7 in chromosome III 0.0017 0.0068 0.0022

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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