Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | alpha-amylase | 0.0077 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Probable alpha-glucosidase AglA (maltase) (glucoinvertase) (glucosidosucrase) (maltase-glucoamylase) (lysosomal alpha-glucosidas | 0.0077 | 0.5 | 0.5 |
Schistosoma mansoni | alpha-amylase | 0.0077 | 0.5 | 0.5 |
Echinococcus granulosus | alpha glucosidase | 0.0077 | 0.5 | 0.5 |
Schistosoma mansoni | alpha-amylase | 0.0077 | 0.5 | 0.5 |
Mycobacterium leprae | Putative uncharacterized protein ML2045 | 0.0077 | 0.5 | 0.5 |
Echinococcus multilocularis | alpha glucosidase | 0.0077 | 0.5 | 0.5 |
Brugia malayi | Alpha amylase, catalytic domain containing protein | 0.0077 | 0.5 | 0.5 |
Mycobacterium ulcerans | trehalose synthase TreS | 0.0077 | 0.5 | 0.5 |
Entamoeba histolytica | oligo-1,6-glucosidase, putative | 0.0077 | 0.5 | 0.5 |
Loa Loa (eye worm) | alpha amylase | 0.0077 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Trehalose synthase TreS | 0.0077 | 0.5 | 0.5 |
Loa Loa (eye worm) | alpha amylase | 0.0077 | 0.5 | 0.5 |
Schistosoma mansoni | alpha-amylase | 0.0077 | 0.5 | 0.5 |
Schistosoma mansoni | alpha-amylase | 0.0077 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.