Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0033 | 0.0188 | 0.013 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0048 | 0.042 | 1 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0402 | 0.5668 | 0.5657 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0402 | 0.5668 | 0.5657 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Schistosoma mansoni | hypothetical protein | 0.0493 | 0.7019 | 0.6987 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0055 | 0.0519 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0158 | 0.0132 |
Brugia malayi | hypothetical protein | 0.0181 | 0.2389 | 0.3303 |
Onchocerca volvulus | 0.0049 | 0.0422 | 0.0573 | |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0493 | 0.7019 | 0.7011 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0031 | 0.0158 | 0.3767 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0048 | 0.042 | 1 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0048 | 0.042 | 1 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0048 | 0.042 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0158 | 0.0088 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0507 | 0.7224 | 0.7217 |
Schistosoma mansoni | transcription factor btf3 | 0.0035 | 0.0224 | 0.0121 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Brugia malayi | Endoplasmin precursor | 0.0033 | 0.0188 | 0.0119 |
Echinococcus granulosus | lamin | 0.0027 | 0.0105 | 0.0079 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0035 | 0.0224 | 0.4086 |
Echinococcus multilocularis | geminin | 0.0171 | 0.2231 | 0.2211 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0158 | 0.0088 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0035 | 0.0224 | 0.0939 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.2389 | 0.3311 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0105 | 0.0079 |
Schistosoma mansoni | apoptosis regulator bax | 0.0493 | 0.7019 | 0.6987 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0138 | 0.1747 | 0.1725 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Brugia malayi | hypothetical protein | 0.0048 | 0.042 | 0.0456 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Brugia malayi | heat shock protein 90 | 0.0033 | 0.0188 | 0.0119 |
Onchocerca volvulus | Huntingtin homolog | 0.0123 | 0.1531 | 0.2574 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0035 | 0.0224 | 1 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0048 | 0.042 | 1 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0033 | 0.0188 | 1 |
Mycobacterium leprae | PROBABLE ISOCITRATE LYASE AceA (ISOCITRASE) (ISOCITRATASE) (ICL) | 0.0502 | 0.7146 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) | 0.0502 | 0.7146 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0224 | 0.5335 |
Echinococcus granulosus | geminin | 0.0171 | 0.2231 | 0.2211 |
Schistosoma mansoni | loxhd1 | 0.0181 | 0.2389 | 0.2308 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0048 | 0.042 | 1 |
Brugia malayi | Doublecortin family protein | 0.0181 | 0.2389 | 0.3303 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0031 | 0.0158 | 0.2099 |
Leishmania major | basic transcription factor 3a, putative | 0.0035 | 0.0224 | 0.4086 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Mycobacterium ulcerans | isocitrate lyase Icl | 0.0502 | 0.7146 | 1 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.005 | 0.0444 | 0.0419 |
Schistosoma mansoni | single-minded | 0.0186 | 0.2465 | 0.2385 |
Onchocerca volvulus | 0.0031 | 0.0158 | 0.0096 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0224 | 0.5335 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0048 | 0.042 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0181 | 0.2389 | 0.3311 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0035 | 0.0224 | 0.0167 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.2231 | 0.2149 |
Treponema pallidum | heat shock protein 90 | 0.0026 | 0.0089 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0158 | 0.0132 |
Loa Loa (eye worm) | ICD-1 protein | 0.0035 | 0.0224 | 0.0183 |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0493 | 0.7019 | 0.7011 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0493 | 0.7019 | 0.7011 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Brugia malayi | bHLH-PAS transcription factor | 0.0138 | 0.1747 | 0.2375 |
Loa Loa (eye worm) | hypothetical protein | 0.0352 | 0.4927 | 0.6977 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.042 | 0.0466 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0033 | 0.0188 | 0.2979 |
Mycobacterium ulcerans | isocitrate lyase AceAb | 0.0502 | 0.7146 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 0.0158 | 0.0132 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0181 | 0.2389 | 0.2369 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0158 | 0.0077 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Leishmania major | protein kinase, putative | 0.0048 | 0.042 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.0089 | 0.2111 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0158 | 0.0088 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0033 | 0.0188 | 0.4428 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0158 | 0.0077 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0033 | 0.0188 | 0.2979 |
Onchocerca volvulus | 0.0031 | 0.0158 | 0.0096 | |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0048 | 0.042 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0224 | 1 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0181 | 0.2389 | 0.2369 |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0493 | 0.7019 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0422 | 0.0459 |
Onchocerca volvulus | 0.0401 | 0.5644 | 1 | |
Echinococcus granulosus | endoplasmin | 0.0026 | 0.0089 | 0.0063 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0048 | 0.042 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.3231 | 0.4527 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0031 | 0.0158 | 0.0099 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0048 | 0.042 | 1 |
Loa Loa (eye worm) | endoplasmin | 0.0033 | 0.0188 | 0.013 |
Trypanosoma cruzi | aldo-keto reductase | 0.0031 | 0.0158 | 0.2099 |
Onchocerca volvulus | 0.0031 | 0.0158 | 0.0096 | |
Schistosoma mansoni | rab6-interacting | 0.0181 | 0.2389 | 0.2308 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0031 | 0.0158 | 0.2099 |
Echinococcus multilocularis | endoplasmin | 0.0026 | 0.0089 | 0.0063 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0035 | 0.0224 | 0.4086 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0181 | 0.2389 | 0.2369 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0033 | 0.0188 | 0.2979 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0224 | 0.5335 |
Schistosoma mansoni | rab6-interacting | 0.0181 | 0.2389 | 0.2308 |
Toxoplasma gondii | NAC domain-containing protein | 0.0035 | 0.0224 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.005 | 0.0444 | 0.0501 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0105 | 0.0011 |
Schistosoma mansoni | lipoxygenase | 0.0181 | 0.2389 | 0.2308 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0158 | 0.0077 |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 0.0158 | 0.0132 |
Brugia malayi | PAS domain containing protein | 0.0186 | 0.2465 | 0.3413 |
Echinococcus multilocularis | heat shock protein 90 | 0.0026 | 0.0089 | 0.0063 |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 0.0158 | 0.0132 |
Leishmania major | protein kinase, putative | 0.0048 | 0.042 | 1 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0507 | 0.7224 | 0.7217 |
Echinococcus multilocularis | RUN | 0.0181 | 0.2389 | 0.2369 |
Schistosoma mansoni | polycystin 1-related | 0.0181 | 0.2389 | 0.2308 |
Onchocerca volvulus | 0.0031 | 0.0158 | 0.0096 | |
Mycobacterium ulcerans | oxidoreductase | 0.0031 | 0.0158 | 0.0099 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0026 | 0.0089 | 0.0063 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0493 | 0.7019 | 0.7011 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0048 | 0.042 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0694 | 1 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0181 | 0.2389 | 0.2369 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Echinococcus granulosus | heat shock protein 90 | 0.0033 | 0.0188 | 0.0162 |
Echinococcus granulosus | transcription factor btf3 | 0.0035 | 0.0224 | 0.0198 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0033 | 0.0188 | 0.2979 |
Echinococcus multilocularis | transcription factor btf3 | 0.0035 | 0.0224 | 0.0198 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0105 | 0.0079 |
Loa Loa (eye worm) | doublecortin family protein | 0.0181 | 0.2389 | 0.3311 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0026 | 0.0089 | 0.0088 |
Echinococcus multilocularis | heat shock protein | 0.0033 | 0.0188 | 0.0162 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0493 | 0.7019 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.0031 | 0.0158 | 0.2099 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0158 | 0.0088 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0033 | 0.0188 | 0.4428 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0105 | 0.0079 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0033 | 0.0188 | 0.4428 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0048 | 0.042 | 1 |
Mycobacterium leprae | Possible regulatory protein | 0.0048 | 0.042 | 0.0553 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0105 | 0.0011 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0033 | 0.0188 | 0.4428 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0158 | 0.0132 |
Onchocerca volvulus | 0.0031 | 0.0158 | 0.0096 | |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0181 | 0.2389 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Mycobacterium tuberculosis | Isocitrate lyase Icl (isocitrase) (isocitratase) | 0.0502 | 0.7146 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0105 | 0.0011 |
Brugia malayi | hypothetical protein | 0.0238 | 0.3231 | 0.4522 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0031 | 0.0158 | 0.0185 |
Schistosoma mansoni | pol-related | 0.0031 | 0.0158 | 0.0054 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.0089 | 0.2111 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0048 | 0.042 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0493 | 0.7019 | 0.6987 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0238 | 0.3231 | 0.3213 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0105 | 0.0079 |
Onchocerca volvulus | Huntingtin homolog | 0.0123 | 0.1531 | 0.2574 |
Loa Loa (eye worm) | hypothetical protein | 0.0354 | 0.495 | 0.7011 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0105 | 0.0079 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0048 | 0.042 | 1 |
Echinococcus granulosus | heat shock protein 90 | 0.0026 | 0.0089 | 0.0063 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Loa Loa (eye worm) | hypothetical protein | 0.0493 | 0.7019 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0048 | 0.042 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.1531 | 0.2071 |
Leishmania major | prostaglandin f synthase, putative | 0.0031 | 0.0158 | 0.2099 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.1531 | 0.2071 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0158 | 0.0132 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0181 | 0.2389 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0031 | 0.0158 | 0.3767 |
Echinococcus granulosus | single minded 2 | 0.0138 | 0.1747 | 0.1725 |
Schistosoma mansoni | aldo-keto reductase | 0.0031 | 0.0158 | 0.0054 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Onchocerca volvulus | 0.0139 | 0.1771 | 0.3007 | |
Schistosoma mansoni | lipoxygenase | 0.0507 | 0.7224 | 0.7195 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Schistosoma mansoni | endoplasmin | 0.0033 | 0.0188 | 0.0083 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Giardia lamblia | Aldose reductase | 0.0031 | 0.0158 | 0.7046 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Onchocerca volvulus | 0.0181 | 0.2389 | 0.4123 | |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Schistosoma mansoni | heat shock protein | 0.0033 | 0.0188 | 0.0083 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.005 | 0.0444 | 0.0419 |
Schistosoma mansoni | heat shock protein | 0.0033 | 0.0188 | 0.0083 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0048 | 0.042 | 1 |
Plasmodium falciparum | heat shock protein 90 | 0.0033 | 0.0188 | 0.0785 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.0089 | 0.2111 |
Echinococcus granulosus | hypothetical protein | 0.0031 | 0.0158 | 0.0132 |
Schistosoma mansoni | endoplasmin | 0.0033 | 0.0188 | 0.0083 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0035 | 0.0224 | 1 |
Brugia malayi | hypothetical protein | 0.0123 | 0.1531 | 0.2062 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0031 | 0.0158 | 0.3767 |
Echinococcus granulosus | heat shock protein | 0.0033 | 0.0188 | 0.0162 |
Schistosoma mansoni | hypothetical protein | 0.0181 | 0.2389 | 0.2308 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0238 | 0.3231 | 0.3213 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Brugia malayi | beta-NAC-like protein | 0.0035 | 0.0224 | 0.0173 |
Onchocerca volvulus | 0.0031 | 0.0158 | 0.0096 | |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0493 | 0.7019 | 0.6987 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0181 | 0.2389 | 0.2369 |
Echinococcus multilocularis | heat shock protein 90 | 0.0033 | 0.0188 | 0.0162 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0158 | 0.0088 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0158 | 0.0088 |
Mycobacterium ulcerans | putative regulatory protein | 0.0138 | 0.1747 | 0.2349 |
Giardia lamblia | Aldose reductase | 0.0031 | 0.0158 | 0.7046 |
Brugia malayi | aryl hydrocarbon receptor AHR-1 | 0.0352 | 0.4927 | 0.6974 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0031 | 0.0158 | 0.2099 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0188 | 0.4428 |
Trichomonas vaginalis | heat shock protein, putative | 0.0033 | 0.0188 | 0.4461 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0048 | 0.042 | 1 |
Brugia malayi | hypothetical protein | 0.0181 | 0.2389 | 0.3303 |
Loa Loa (eye worm) | hypothetical protein | 0.0401 | 0.5644 | 0.8014 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0158 | 0.0132 |
Schistosoma mansoni | hypothetical protein | 0.0493 | 0.7019 | 0.6987 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0422 | 0.0321 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0422 | 0.0321 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.2231 | 0.2149 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0048 | 0.042 | 1 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0033 | 0.0188 | 0.4428 |
Onchocerca volvulus | 0.0181 | 0.2389 | 0.4123 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0158 | 0.0132 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0033 | 0.0188 | 0.2979 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.054 | 0.7712 | 0.7688 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0033 | 0.0188 | 0.4428 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0181 | 0.2389 | 0.2369 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) | 0.0502 | 0.7146 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0158 | 0.3767 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0026 | 0.0089 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0031 | 0.0158 | 0.0054 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0694 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0188 | 0.2979 |
Mycobacterium leprae | Isocitrate lyase | 0.0235 | 0.3192 | 0.4446 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0033 | 0.0188 | 0.4428 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0158 | 0.0077 |
Echinococcus granulosus | RUN | 0.0181 | 0.2389 | 0.2369 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = -1.2 % | Activation of human estrogen receptor alpha expressed in HEK293 cells at 10 uM by beta-galactosidase reporter gene assay relative to 3,17 beta-estradiol | ChEMBL. | 18517258 |
Activity (binding) | = 5.8 % | Activation of human estrogen receptor beta expressed in HEK293 cells at 10 uM beta-galactosidase reporter gene assay relative to 3,17-beta-estradiol | ChEMBL. | 18517258 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.