Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0597 | 0.292 | 0.292 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1043 | 0.6419 | 0.6419 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0556 | 0.2602 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Onchocerca volvulus | 0.1043 | 0.6419 | 1 | |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0332 | 0.084 | 0.084 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1043 | 0.6419 | 0.6419 |
Trypanosoma cruzi | cysteine protease, putative | 0.0556 | 0.2602 | 0.2602 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1043 | 0.6419 | 0.6419 |
Brugia malayi | Cathepsin L-like precursor | 0.0711 | 0.3817 | 0.3817 |
Leishmania major | cathepsin L-like protease | 0.1043 | 0.6419 | 1 |
Leishmania major | cathepsin L-like protease | 0.1043 | 0.6419 | 1 |
Echinococcus multilocularis | cathepsin b | 0.1499 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.1499 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0332 | 0.084 | 0.084 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0642 | 0.3278 | 0.5106 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0556 | 0.2602 | 0.2602 |
Onchocerca volvulus | Cathepsin L homolog | 0.1043 | 0.6419 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0711 | 0.3817 | 0.3817 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1043 | 0.6419 | 0.6419 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1043 | 0.6419 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0556 | 0.2602 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0556 | 0.2602 | 0.4054 |
Echinococcus granulosus | cathepsin b | 0.1499 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1043 | 0.6419 | 0.6419 |
Onchocerca volvulus | 0.1043 | 0.6419 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0556 | 0.2602 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1043 | 0.6419 | 0.6419 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0687 | 0.3633 | 0.3633 |
Echinococcus granulosus | cysteine protease | 0.0556 | 0.2602 | 0.2602 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1499 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0619 | 0.3093 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1043 | 0.6419 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1043 | 0.6419 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0556 | 0.2602 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1043 | 0.6419 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0751 | 0.4128 | 0.4128 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0687 | 0.3633 | 0.3633 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1043 | 0.6419 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1043 | 0.6419 | 0.6419 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0556 | 0.2602 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0556 | 0.2602 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1043 | 0.6419 | 0.6419 |
Leishmania major | cathepsin L-like protease | 0.1043 | 0.6419 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.1043 | 0.6419 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1043 | 0.6419 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0556 | 0.2602 | 0.4054 |
Onchocerca volvulus | 0.1043 | 0.6419 | 1 | |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0711 | 0.3817 | 0.3817 |
Entamoeba histolytica | cysteine protease, putative | 0.0556 | 0.2602 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1043 | 0.6419 | 1 |
Onchocerca volvulus | 0.0711 | 0.3817 | 0.5946 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0332 | 0.084 | 0.084 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1043 | 0.6419 | 0.6419 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0332 | 0.084 | 0.084 |
Brugia malayi | Cathepsin L-like precursor | 0.1043 | 0.6419 | 0.6419 |
Loa Loa (eye worm) | hypothetical protein | 0.0711 | 0.3817 | 0.3817 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1043 | 0.6419 | 0.6419 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1043 | 0.6419 | 0.6419 |
Entamoeba histolytica | cysteine protease, putative | 0.0556 | 0.2602 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0556 | 0.2602 | 0.4054 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1043 | 0.6419 | 0.6419 |
Plasmodium vivax | vivapain-2 | 0.1043 | 0.6419 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1499 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0556 | 0.2602 | 0.4054 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0687 | 0.3633 | 0.3633 |
Loa Loa (eye worm) | cysteine protease | 0.1043 | 0.6419 | 0.6419 |
Plasmodium vivax | unspecified product | 0.0556 | 0.2602 | 0.4054 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0556 | 0.2602 | 0.2602 |
Schistosoma mansoni | cathepsin s | 0.0332 | 0.084 | 0.084 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0687 | 0.3633 | 0.3633 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0711 | 0.3817 | 0.3817 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0332 | 0.084 | 0.084 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1043 | 0.6419 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.1043 | 0.6419 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0332 | 0.084 | 0.084 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0711 | 0.3817 | 0.5946 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0711 | 0.3817 | 0.5946 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1043 | 0.6419 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0619 | 0.3093 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0556 | 0.2602 | 0.4054 |
Brugia malayi | cathepsin L-like precursor | 0.0711 | 0.3817 | 0.3817 |
Entamoeba histolytica | cysteine protease, putative | 0.0556 | 0.2602 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.1043 | 0.6419 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0556 | 0.2602 | 0.2602 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1043 | 0.6419 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0711 | 0.3817 | 0.3817 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0556 | 0.2602 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0619 | 0.3093 | 0.3093 |
Leishmania major | cathepsin L-like protease | 0.1043 | 0.6419 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1043 | 0.6419 | 0.6419 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0556 | 0.2602 | 0.2602 |
Echinococcus granulosus | cathepsin l1 | 0.0711 | 0.3817 | 0.3817 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0332 | 0.084 | 0.084 |
Entamoeba histolytica | cysteine protease, putative | 0.0556 | 0.2602 | 0.4054 |
Echinococcus multilocularis | cathepsin L | 0.0556 | 0.2602 | 0.2602 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1043 | 0.6419 | 0.6419 |
Loa Loa (eye worm) | hypothetical protein | 0.0711 | 0.3817 | 0.3817 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0556 | 0.2602 | 0.2602 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1043 | 0.6419 | 0.6419 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1043 | 0.6419 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0619 | 0.3093 | 0.4818 |
Plasmodium vivax | unspecified product | 0.0332 | 0.084 | 0.1309 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Leishmania major | cathepsin L-like protease | 0.1043 | 0.6419 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1043 | 0.6419 | 0.6419 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1043 | 0.6419 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0556 | 0.2602 | 0.2602 |
Entamoeba histolytica | cysteine protease, putative | 0.1043 | 0.6419 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1043 | 0.6419 | 0.6419 |
Toxoplasma gondii | cathepsin B | 0.0619 | 0.3093 | 0.4818 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0711 | 0.3817 | 0.3817 |
Onchocerca volvulus | Cathepsin F homolog | 0.1043 | 0.6419 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1043 | 0.6419 | 0.6419 |
Loa Loa (eye worm) | hypothetical protein | 0.0332 | 0.084 | 0.084 |
Plasmodium vivax | vivapain-1 | 0.0556 | 0.2602 | 0.4054 |
Onchocerca volvulus | 0.1043 | 0.6419 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0556 | 0.2602 | 0.4054 |
Giardia lamblia | Cathepsin B precursor | 0.0619 | 0.3093 | 1 |
Loa Loa (eye worm) | fibroinase | 0.1043 | 0.6419 | 0.6419 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1043 | 0.6419 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0619 | 0.3093 | 0.3093 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1499 | 1 | 1 |
Onchocerca volvulus | 0.1043 | 0.6419 | 1 | |
Leishmania major | cathepsin L-like protease | 0.1043 | 0.6419 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0556 | 0.2602 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0711 | 0.3817 | 0.5946 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0556 | 0.2602 | 0.2602 |
Echinococcus multilocularis | cathepsin b | 0.1499 | 1 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.1043 | 0.6419 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0556 | 0.2602 | 0.2602 |
Onchocerca volvulus | 0.1043 | 0.6419 | 1 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0556 | 0.2602 | 0.2602 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0619 | 0.3093 | 0.1285 |
Loa Loa (eye worm) | cathepsin B | 0.0619 | 0.3093 | 0.3093 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0556 | 0.2602 | 0.2602 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1043 | 0.6419 | 0.6419 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0642 | 0.3278 | 0.5106 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.1043 | 0.6419 | 0.6419 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1043 | 0.6419 | 0.6419 |
Loa Loa (eye worm) | hypothetical protein | 0.1499 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1043 | 0.6419 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1043 | 0.6419 | 1 |
Echinococcus granulosus | cathepsin L | 0.0556 | 0.2602 | 0.2602 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1499 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0556 | 0.2602 | 0.4054 |
Echinococcus granulosus | cathepsin l1 | 0.1043 | 0.6419 | 0.6419 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1043 | 0.6419 | 0.6419 |
Brugia malayi | Cathepsin L-like precursor | 0.0332 | 0.084 | 0.084 |
Plasmodium vivax | vivapain-3 | 0.0556 | 0.2602 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1043 | 0.6419 | 1 |
Echinococcus multilocularis | cysteine protease | 0.1043 | 0.6419 | 0.6419 |
Onchocerca volvulus | 0.1043 | 0.6419 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1043 | 0.6419 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0751 | 0.4128 | 0.4128 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0556 | 0.2602 | 0.4054 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1499 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.1043 | 0.6419 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1043 | 0.6419 | 0.6419 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0556 | 0.2602 | 0.4054 |
Echinococcus multilocularis | cysteine protease | 0.1043 | 0.6419 | 0.6419 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0556 | 0.2602 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1043 | 0.6419 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.