Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1563 | 0.1797 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0042 | 0.1563 | 0.1797 |
Entamoeba histolytica | hypothetical protein | 0.0029 | 0.0841 | 1 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0019 | 0.0301 | 0.0897 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0857 | 0.0975 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0714 | 0.2893 |
Echinococcus granulosus | geminin | 0.014 | 0.6758 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0013 | 0.0018 | 0.0027 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.0714 | 0.0605 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.0714 | 0.0431 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0054 | 0.2183 | 0.323 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0841 | 0.0956 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0714 | 0.7677 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0123 | 0.5872 | 0.5824 |
Plasmodium falciparum | glutathione reductase | 0.0019 | 0.0301 | 0.0897 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0015 | 0.0116 | 0.0172 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0103 | 0.4811 | 0.5668 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0103 | 0.4811 | 0.5668 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0029 | 0.0841 | 0.1244 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.318 | 0.3678 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0296 | 0.0438 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0306 | 0.0335 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Onchocerca volvulus | 0.0175 | 0.8615 | 1 | |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0296 | 0.0871 |
Plasmodium falciparum | thioredoxin reductase | 0.0019 | 0.0301 | 0.0897 |
Echinococcus granulosus | GPCR family 2 | 0.0013 | 0.0018 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0848 | 0.1 |
Mycobacterium tuberculosis | Probable transcriptional regulatory protein | 0.0201 | 1 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0019 | 0.0301 | 0.0897 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0014 | 0.0036 | 0.0021 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0857 | 0.3583 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0296 | 0.0438 |
Plasmodium falciparum | acyl-CoA synthetase | 0.002 | 0.0357 | 0.1168 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0296 | 0.0871 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Mycobacterium ulcerans | putative regulatory protein | 0.0201 | 1 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0054 | 0.2183 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0103 | 0.4811 | 0.7119 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0296 | 0.0182 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0018 | 0.0022 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0714 | 0.0431 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0029 | 0.0841 | 0.099 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.0357 | 0.0244 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Mycobacterium tuberculosis | Probable reductase | 0.0123 | 0.5872 | 0.5824 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0857 | 0.3583 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0714 | 0.2893 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0301 | 0.0897 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0019 | 0.0301 | 0.0897 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0857 | 0.3583 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0137 | 0.6606 | 0.6566 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0296 | 0.0871 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0841 | 0.099 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0714 | 0.0809 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0019 | 0.0301 | 0.0355 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0116 | 0.0172 |
Echinococcus multilocularis | GPCR, family 2 | 0.0013 | 0.0018 | 0.0027 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0296 | 0.0323 |
Toxoplasma gondii | thioredoxin reductase | 0.0054 | 0.2183 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0103 | 0.4811 | 0.7119 |
Loa Loa (eye worm) | hypothetical protein | 0.0175 | 0.8615 | 1 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0296 | 0.0349 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0019 | 0.0301 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0029 | 0.0841 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0857 | 0.3583 |
Entamoeba histolytica | hypothetical protein | 0.0029 | 0.0841 | 1 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0019 | 0.0301 | 0.0897 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0301 | 0.0897 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0123 | 0.5872 | 0.5824 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0137 | 0.6574 | 0.7627 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0301 | 0.0897 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0054 | 0.2183 | 0.2518 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0015 | 0.0116 | 0.0137 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0019 | 0.0301 | 0.0446 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0857 | 0.0975 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0019 | 0.0301 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0116 | 0.0172 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0296 | 0.0871 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0296 | 0.0323 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0301 | 0.0897 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0123 | 0.5872 | 0.5824 |
Brugia malayi | Isocitrate dehydrogenase | 0.0015 | 0.0116 | 0.0113 |
Mycobacterium ulcerans | two component transcriptional regulator | 0.0201 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.014 | 0.6758 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0054 | 0.2183 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Mycobacterium tuberculosis | Probable transcriptional regulatory protein (probably LuxR/UhpA-family) | 0.0201 | 1 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0019 | 0.0301 | 0.0897 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0103 | 0.4811 | 0.7119 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0019 | 0.0301 | 0.0897 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.03 | 0.0186 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0054 | 0.2183 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0714 | 0.0809 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0019 | 0.0301 | 0.0188 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0296 | 0.0323 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0714 | 0.0431 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0103 | 0.4811 | 0.5575 |
Brugia malayi | isocitrate dehydrogenase | 0.0015 | 0.0116 | 0.0113 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0301 | 0.0897 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0019 | 0.0301 | 0.0897 |
Mycobacterium tuberculosis | Possible two component transcriptional regulatory protein (probably LuxR-family) | 0.0201 | 1 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0123 | 0.5872 | 0.5824 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0714 | 0.0809 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0018 | 0.0022 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0123 | 0.5872 | 0.5555 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0296 | 0.0438 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0029 | 0.0841 | 0.1244 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0116 | 0.0172 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0296 | 0.0438 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0103 | 0.4811 | 0.7119 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0013 | 0.0018 | 0.0027 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.0714 | 0.0431 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0296 | 0.0871 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0296 | 0.0182 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0394 |
Brugia malayi | glutathione reductase | 0.0054 | 0.2183 | 0.2518 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0019 | 0.0301 | 0.0005 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0018 | 0.0022 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0019 | 0.0301 | 0.5 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0296 | 0.0871 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0054 | 0.2183 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0103 | 0.4811 | 0.5668 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0296 | 0.0438 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0015 | 0.0116 | 0.0172 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.0714 | 0.0431 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0014 | 0.0036 | 0.0021 |
Brugia malayi | Thioredoxin reductase | 0.0054 | 0.2183 | 0.2518 |
Brugia malayi | MH2 domain containing protein | 0.0137 | 0.6574 | 0.7627 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.0857 | 0.3583 |
Plasmodium vivax | glutathione reductase, putative | 0.0054 | 0.2183 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0857 | 0.3583 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0019 | 0.0301 | 0.0897 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0857 | 0.3583 |
Schistosoma mansoni | hypothetical protein | 0.014 | 0.6758 | 0.7963 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0019 | 0.0301 | 0.0897 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0137 | 0.6606 | 0.6566 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0123 | 0.5872 | 0.5824 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0394 |
Schistosoma mansoni | eyes absent homolog | 0.0073 | 0.318 | 0.3747 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.0714 | 0.0431 |
Mycobacterium tuberculosis | Possible nitrate/nitrite response transcriptional regulatory protein NarL | 0.0201 | 1 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0054 | 0.2183 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0296 | 0.0323 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.0714 | 0.7677 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0137 | 0.6574 | 0.7627 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0296 | 0.0349 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0013 | 0.0018 | 0.0027 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0019 | 0.0301 | 0.0446 |
Loa Loa (eye worm) | glutathione reductase | 0.0054 | 0.2183 | 0.2518 |
Mycobacterium tuberculosis | Probable transcriptional regulatory protein (LuxR-family) | 0.0201 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0394 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.318 | 0.3678 |
Mycobacterium ulcerans | two component transcriptional regulatory protein DevR | 0.0201 | 1 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0714 | 0.2893 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0029 | 0.0848 | 0.0965 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0019 | 0.0301 | 0.0329 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0714 | 0.0431 |
Leishmania major | trypanothione reductase | 0.0054 | 0.2183 | 1 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0019 | 0.0301 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0394 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.03 | 0.0186 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0018 | 0.0022 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0019 | 0.0301 | 0.0897 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0357 | 0.0394 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0042 | 0.1563 | 0.1797 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.03 | 0.0186 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0296 | 0.0438 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0296 | 0.0871 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0019 | 0.0301 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0029 | 0.0841 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0019 | 0.0301 | 0.0897 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0013 | 0.0018 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.014 | 0.6758 | 0.7963 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0137 | 0.6606 | 0.6345 |
Treponema pallidum | NADH oxidase | 0.0019 | 0.0301 | 0.5 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0019 | 0.0301 | 0.0005 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0054 | 0.2183 | 0.2091 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.03 | 0.0186 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0019 | 0.0301 | 0.0897 |
Mycobacterium ulcerans | nitrate/nitrite response regulator protein NarL | 0.0201 | 1 | 1 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0019 | 0.0301 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0714 | 0.7677 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.002 | 0.0357 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0714 | 0.0809 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0857 | 0.3583 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0019 | 0.0301 | 0.0897 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0714 | 0.0809 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0019 | 0.0301 | 0.0897 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0296 | 0.0871 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0714 | 0.0809 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0301 | 0.0897 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0054 | 0.2183 | 0.323 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0848 | 0.0965 |
Brugia malayi | hypothetical protein | 0.0073 | 0.318 | 0.3678 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.002 | 0.0357 | 0.0063 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0015 | 0.0116 | 0.0113 |
Mycobacterium tuberculosis | Possible transcriptional regulatory protein | 0.0201 | 1 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0301 | 0.0897 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0019 | 0.0301 | 0.0897 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0137 | 0.6606 | 0.6566 |
Mycobacterium ulcerans | hypothetical protein | 0.0201 | 1 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.0714 | 0.0605 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0019 | 0.0301 | 0.0897 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.002 | 0.0357 | 0.1168 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0296 | 0.0871 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0042 | 0.1563 | 0.1797 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.0714 | 0.0431 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0296 | 0.0349 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0116 | 0.0172 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0103 | 0.4811 | 0.5575 |
Brugia malayi | hypothetical protein | 0.0175 | 0.8615 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.