Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | glycogen phosphorylase | 0.1581 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.023 | 0.023 |
Loa Loa (eye worm) | hypothetical protein | 0.059 | 0.3606 | 0.3606 |
Echinococcus multilocularis | glycogen phosphorylase | 0.1581 | 1 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0044 | 0.0084 | 0.0084 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0031 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0429 | 0.0429 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0097 | 0.0429 | 0.0429 |
Echinococcus granulosus | glycogen phosphorylase | 0.1581 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.1581 | 1 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.1581 | 1 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0097 | 0.0429 | 0.0429 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0031 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.023 | 0.023 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0097 | 0.0429 | 0.0429 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.1581 | 1 | 1 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.1581 | 1 | 1 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0684 | 0.4211 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.1581 | 1 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.1581 | 1 | 1 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.1581 | 1 | 1 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0031 | 0 | 0.5 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0 | 0.5 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0031 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0684 | 0.4211 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0044 | 0.0084 | 0.0084 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.1581 | 1 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.1581 | 1 | 0.5 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0031 | 0 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.1581 | 1 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0031 | 0 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0066 | 0.023 | 0.023 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.1581 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.059 | 0.3606 | 0.3606 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.1581 | 1 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0031 | 0 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.1581 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0684 | 0.4211 | 0.4211 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.