Detailed view for TVAG_198550

Basic information

TDR Targets ID: 858096
Trichomonas vaginalis, calcium binding protein, putative
Source Database / ID: 

pI: 3.7981 | Length (AA): 154 | MW (Da): 17355 | Paralog Number: 3

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG2

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF13499   EF-hand domain pair
PF13833   EF-hand domain pair

Gene Ontology

Mouse over links to read term descriptions.
GO:0005509   calcium ion binding  

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

No model available for this protein in Modbase.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_142876)

Species Accession Gene Product
Dictyostelium discoideum DDB_G0279681   calcium-binding EF-hand domain-containing protein
Dictyostelium discoideum DDB_G0272827   EF-hand domain-containing protein
Dictyostelium discoideum DDB_G0267456   calcium-binding protein
Entamoeba histolytica EHI_067590   troponin-like protein, putative
Trichomonas vaginalis TVAG_521790   calmodulin, putative
Trichomonas vaginalis TVAG_254790   calmodulin, putative
Trichomonas vaginalis TVAG_367580   calmodulin, putative
Trichomonas vaginalis TVAG_198550   calcium binding protein, putative

Essentiality

No essentiality data collected for this gene and/or its orthologs.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Non orthologous druggable targets
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model
No druggable targets predicted through repurposing network model

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

No literature references available for this target.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

User comments

No user comments are available for this gene. Log in to add comments, or register.

Enter your comment

User ()
Gene identifier TVAG_198550 (Trichomonas vaginalis), calcium binding protein, putative
Title for this comment
Comment